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Articles

Genetic effects of FTO gene insertion/deletion (InDel) on fat-tail measurements and growth traits in Tong sheep

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References

  • Safdarian M, Zamiri MJ, Hashemi M, et al. Relationships of fat-tail dimensions with fat-tail weight and carcass characteristics at different slaughter weights of Torki-Ghashghaii sheep. Meat Sci. 2008;80(3):686–689.
  • China National Commission of Animal Genetic Resources (CNCAGR). Animal Genetic Resources in China ‐ Sheep and Goats. Beijing, China: China Agriculture Press; 2012.
  • Sassizaidy YB, Maretto F, Charfi-Cheikhrouha F, et al. Genetic structure and variability within and among populations of the fat-tailed Barbarine sheep breed using microsatellites markers. African Journal of Biotechnology 2014;13(1):44–54.
  • Yuan Z, Liu E, Liu Z, et al. Selection signature analysis reveals genes associated with tail type in Chinese indigenous sheep. Anim Genet. 2017;48(1):55–66.
  • Kang DJ, Zhou GX, Zhou SW, et al. Comparative transcriptome analysis reveals potentially novel roles of Homeobox genes in adipose deposition in fat-tailed sheep. Sci Rep. 2017;7(1):14491.
  • Wood JD, Enser M, Fisher AV, et al. Fat deposition, fatty acid composition and meat quality: A review. Meat Sci. 2008;78(4):343–358.
  • Nayak SN, Singh VK, Varshney RK. Marker-assisted selection. In: Thomas B, Murray BG, Murphy DJ, eds. Encyclopedia of Applied Plant Sciences. Waltham, MA: Academic Press; 2017:183–197.
  • Loos RJF, Yeo GSH. The bigger picture of FTO: the first GWAS-identified obesity gene. Nat Rev Endocrinol. 2014;10(1):51–61.
  • Loos RJ, Bouchard C. FTO: the first gene contributing to common forms of human obesity. Obesity Rev. 2008;9(3):246–250.
  • Christian D, David M, Sophie G. Variation in FTO contributes to childhood obesity and severe adult obesity. Nature Genet. 2007;39(6):724–726.
  • Frayling TM, Timpson NJ, Weedon MN, et al. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007;316(5826):889–894.
  • Grunnet LG, Nilsson E, Ling C, et al. Regulation and function of FTO mRNA expression in human skeletal muscle and subcutaneous adipose tissue. Diabetes 2009;58(10):2402–2408.
  • Janetta H, Lize VDM, Zaahl MG, et al. Fat mass and obesity-associated (FTO) gene polymorphisms are associated with physical activity, food intake, eating behaviors, psychological health, and modeled change in body mass index in overweight/obese Caucasian adults. Nutrients 2014;6(8):3130–3152.
  • Justiina R, Huusko TJ, Raija S, et al. Fat mass- and obesity-associated gene FTO affects the dietary response in mouse white adipose tissue. Sci Rep. 2015;5:9233.
  • Chen XL, Luo YL, Jia G, et al. FTO promotes adipogenesis through inhibition of the wnt/β-catenin signaling pathway in porcine intramuscular preadipocytes. Anim Biotechnol. 2017;28(4):1–7.
  • Qiong W, Saunders RA, Maria SM, et al. The obesity-associated FTO gene is a transcriptional coactivator. Biochem Biophys Res Commun. 2010;401(3):390–395.
  • Amélie B, Etienne L, Emmanuelle M, et al. FTO is increased in muscle during type 2 diabetes, and its overexpression in myotubes alters insulin signaling, enhances lipogenesis and ROS production, and induces mitochondrial dysfunction. Diabetes 2011;60(1):258–268.
  • Russell MA, Morgan NG. Conditional expression of the FTO gene product in rat INS-1 cells reveals its rapid turnover and a role in the profile of glucose-induced insulin secretion. Clin Sci. 2011;120(9):403–413.
  • Fontanesi L, Scotti E, Buttazzoni L, et al. The porcine fat mass and obesity associated (FTO) gene is associated with fat deposition in Italian Duroc pigs. Animal Genet. 2009;40(1):90–93.
  • Szydlowski M, Salamon S, Grzes M, et al. SNP in the 5′ flanking region of the pig FTO gene is associated with fatness in Polish Landrace. Livestock Sci. 2012;150(1–3):397–400.
  • Jevsinek SD, Kunej T, Kovac M, et al. FTO gene variants are associated with growth and carcass traits in cattle. Anim Genet. 2016;47(2):219–222.
  • Jia X, Nie Q, Lamont SJ, et al. Variation in sequence and expression of the avian FTO, and association with glucose metabolism, body weight, fatness and body composition in chickens. Int J Obes. 2012;36(8):1054–1061.
  • Zhang GW, Gao L, Chen SY, et al. Single nucleotide polymorphisms in the FTO gene and their association with growth and meat quality traits in rabbits. Gene 2013;527(2):553–557.
  • Stratigopoulos G, Watson E, Hattersley AT, et al. Regulation of FTO/FTM gene expression in mice and humans. Am J Physiol Regul Integr Comp Physiol. 2008;294(2):1185–1196.
  • Madsen MB, Birck MM, Fredholm M, et al. Expression studies of the obesity candidate gene FTO in pig. Anim Biotechnol. 2009;21(1):51–63.
  • Kerstin WH, Eva SL, Johan H. The common rs9939609 gene variant of the fat mass- and obesity-associated gene FTO is related to fat cell lipolysis. J Lipid Res. 2008;49(3):607–611.
  • Li J, Erdenee S, Zhang SL, et al. Genetic effects of PRNP gene insertion/deletion (indel) on phenotypic traits in sheep. Prion 2018;12(1):42–53.
  • Czarnik U, Grzybowski G, Zabolewicz T, et al. Deletion/insertion polymorphism of the prion protein gene (PRNP) in Polish red cattle, Polish White-backed cattle and European bison (Bison bonasus L., 1758). Genetika 2009;45(4):519–525.
  • Shi YY, Lin HE. SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci. Cell Res. 2005;15(2):97–98.
  • Kim SR, Ramos J, Ashikari M, et al. Development and validation of allele-specific SNP/indel markers for eight yield-enhancing genes using whole-genome sequencing strategy to increase yield potential of rice, Oryza sativa L. Rice 2016;9(1):1–17.
  • Dvořáková V, Bartenschlager H, Stratil A, et al. Association between polymorphism in the gene and growth and carcass traits in pig crosses. Genet Sel Evol. 2012;44(1):13.
  • Kandaswamy R, Venkatesan R, Saurabh G, et al. Genetic variations in the FTO gene are associated with type 2 diabetes and obesity in south Indians (CURES-79). Diabetes Technol Ther. 2011;13(1):33–42.
  • Mustafa S, Mujgan OE, Saliha HY, et al. Association of obesity with rs1421085 and rs9939609 polymorphisms of FTO gene. Mol Biol Rep. 2014;41(11):7381–7386.
  • Fan B, Du ZQ, Rothschild MF. The fat mass and obesity-associated (FTO) gene is associated with intramuscular fat content and growth rate in the pig. Anim Biotechnol. 2009;20(2):58–70.
  • Huang XY, Zhao J, Yang MY, et al. Association between FTO gene polymorphism (rs9939609 T/A) and cancer risk: a meta-analysis. Eur J Cancer Care. 2017;26(5):e12464.
  • Xu SS, Ren X, Yang GL, et al. Genome-wide association analysis identifies the genetic basis of fat deposition in the tails of sheep (Ovis aries). Anim Genet. 2017;48(5):560–569.
  • Wang XL, Zhou GX, Xu XC, et al. Transcriptome profile analysis of adipose tissues from fat and short-tailed sheep. Gene 2014;549(2):252–257.
  • Ma L, Li Z, Cai Y, Xu H, et al. Genetic variants in fat- and short-tailed sheep from high-throughput RNA-sequencing data. Anim Genet. 2018;49(5):483–487.
  • Komar AA. Genetics: SNPs, silent but not invisible. Science 2007;315(5811):466–467.
  • Bartosovic M, Molares HC, Gregorova P, et al. N6-methyladenosine demethylase FTO targets pre-mRNAs and regulates alternative splicing and 3'-end processing. Nucl Acids Res. 2017;45(19):11356–11370.
  • Farahani AHK, Shahrbabak HM, Shahrbabak MM, et al. Relationship of fat-tail and body measurements with some economic important traits in fat-tail Makoei breed of Iranian sheep. Afr J Biotechnol. 2010;9(36):5989–5992.

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