Advanced search
Publication Cover
Animal Biotechnology Volume 33, 2022 - Issue 6
Submit an article Journal homepage
273
Views
1
CrossRef citations to date
0
Altmetric
Brief Reports

Identification of a promoter polymorphism affecting GPAT3 gene expression that is likely related to intramuscular fat content in pigs

Cai Maa Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong Agricultural University, Taian, PR ChinaView further author information
,
Yi Suna Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong Agricultural University, Taian, PR ChinaView further author information
,
Jiying Wangb Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, PR ChinaView further author information
,
Li Kanga Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong Agricultural University, Taian, PR ChinaView further author information
&
Yunliang Jianga Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong Agricultural University, Taian, PR ChinaCorrespondence[email protected]
View further author information
Pages 1378-1381 | Published online: 21 Dec 2020

References

  • Hocquette JF, Gondret F, Baéza E, Médale F, Jurie C, Pethick DW. Intramuscular fat content in meat-producing animals: development, genetic and nutritional control, and identification of putative markers. Animal. 2010;4(2):303–319.
  • Yang H, Huang X, Zeng Z, et al. Genome-wide association analysis for blood lipid traits measured in three pig populations reveals a substantial level of genetic heterogeneity. PLoS One. 2015;10(6):e0131667.
  • Wang Y, Ma C, Sun Y, Li Y, Kang L, Jiang Y. Dynamic transcriptome and DNA methylome analyses on longissimus dorsi to identify genes underlying intramuscular fat content in pigs. BMC Genomics. 2017;18(1):780.
  • Ma C, Wang W, Wang Y, et al. TMT-labeled quantitative proteomic analyses on the longissimus dorsi to identify the proteins underlying intramuscular fat content in pigs. J Proteomics. 2020;213:103630.
  • Cao J, Li JL, Li D, Tobin JF, Gimeno RE. Molecular identification of microsomal acyl-CoA: glycerol-3-phosphate acyltransferase, a key enzyme in de novo triacylglycerol synthesis. Proc Natl Acad Sci USA. 2006;103(52):19695–19700.
  • Cao J, Perez S, Goodwin B, et al. Mice deleted for GPAT3 have reduced GPAT activity in white adipose tissue and altered energy and cholesterol homeostasis in diet-induced obesity. Am J Physiol Endocrinol Metab. 2014;306(10):E1176–E1187.
  • Wang K, Liu Y, Xu Q, et al. A post-GWAS confirming GPAT3 gene associated with pig growth and a significant SNP influencing its promoter activity. Anim Genet. 2017;48(4):478–482.
  • Liu G, Wang Y, Jiang S, et al. Suppression of lymphocyte apoptosis in spleen by CXCL13 after porcine circovirus type 2 infection and regulatory mechanism of CXCL13 expression in pigs. Vet Res. 2019;50(1):17.
  • Bongiorni S, Tilesi F, Bicorgna S, et al. Promoter polymorphisms in genes involved in porcine myogenesis influence their transcriptional activity. BMC Genet. 2014;15:119.
  • Shan D, Li JL, Wu L, et al. GPAT3 and GPAT4 are regulated by insulin-stimulated phosphorylation and play distinct roles in adipogenesis. J Lipid Res. 2010;51(7):1971–1198.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.