Detection of polymorphisms in six genes and their association analysis with litter size in sheep

References

• Zhang X, Yuan R, Bai Y, et al. A deletion mutation within the goat AKAP13 gene is significantly associated with litter size. Anim Biotechnol. 2023;34(2):1–11.
   PubMed Web of Science ®Google Scholar
• Abd EL-Hack ME, Abdelnour SA, Swelum AA, et al. The application of gene marker-assisted selection and proteomics for the best meat quality criteria and body measurements in Qinchuan cattle breed. Mol Biol Rep. 2018;45(5):1445–1456.
   PubMed Web of Science ®Google Scholar
• Akhatayeva Z, Bi Y, He Y, et al. Survey of the relationship between polymorphisms within the BMPR1B gene and sheep reproductive traits. Anim Biotechnol. 2023;34(3):718–727.
   PubMedGoogle Scholar
• Chu MX, Yang J, Feng T, et al. GDF9 as a candidate gene for prolificacy of Small Tail Han sheep. Mol Biol Rep. 2011;38(8):5199–5204.
   PubMed Web of Science ®Google Scholar
• Calvo JH, Chantepie L, Serrano M, et al. A new allele in the BMP15 gene (FecX(RA)) that affects prolificacy co-segregates with FecX(R) and FecX(GR) in Rasa Aragonesa sheep. Theriogenology. 2020;144:107–111.
   PubMed Web of Science ®Google Scholar
• Kaman T, Karasakal ÖF, Özkan Oktay E, et al. In silico approach to the analysis of SNPs in the human APAF1 gene. Turk J Biol. 2019;43(6):371–381.
   PubMed Web of Science ®Google Scholar
• Hussein MR. Apoptosis in the ovary: molecular mechanisms. Hum Reprod Update. 2005;11(2):162–177.
   PubMed Web of Science ®Google Scholar
• Deveraux QL, Reed JC. IAP family proteins–suppressors of apoptosis. Genes Dev. 1999;13(3):239–252.
   PubMed Web of Science ®Google Scholar
• Manabe N, Goto Y, Matsuda-Minehata F, et al. Regulation mechanism of selective atresia in porcine follicles: regulation of granulosa cell apoptosis during atresia. J Reprod Dev. 2004;50(5):493–514.
   PubMed Web of Science ®Google Scholar
• Adams HA, Sonstegard TS, Vanraden PM, et al. Identification of a nonsense mutation in APAF1 that is likely causal for a decrease in reproductive efficiency in Holstein dairy cattle. J Dairy Sci. 2016;99(8):6693–6701.
   PubMed Web of Science ®Google Scholar
• Aravind P, Bulbule SR, Hemalatha N, et al. Elevation of gene expression of calcineurin, calmodulin and calsyntenin in oxidative stress induced PC12 cells. Genes Dis. 2021;8(1):87–93.
   PubMed Web of Science ®Google Scholar
• Rindler MJ, Xu CF, Gumper I, et al. Calsyntenins are secretory granule proteins in anterior pituitary gland and pancreatic islet alpha cells. J Histochem Cytochem. 2008;56(4):381–388.
   PubMed Web of Science ®Google Scholar
• Wijayanti D, Bai Y, Hanif Q, et al. Goat CLSTN2 gene: tissue expression profile, genetic variation, and its associations with litter size. Anim Biotechnol. 2022;34(7):2674–2683.
   PubMed Web of Science ®Google Scholar
• Hong EJ, Park SH, Choi KC, et al. Identification of estrogen-regulated genes by microarray analysis of the uterus of immature rats exposed to endocrine disrupting chemicals. Reprod Biol Endocrinol. 2006;4(1):49.
   PubMedGoogle Scholar
• Hernández-Montiel W, Martínez-Núñez MA, Ramón-Ugalde JP, et al. Genome-wide association study reveals candidate genes for litter size traits in Pelibuey sheep. Animals. 2020;10(3):434.
   Web of Science ®Google Scholar
• Jurkowska H, Kaczor-Kamińska M, Bronowicka-Adamska P, et al. Cystathionine γ-lyase. Postepy Hig Med Dosw. 2014;68:1–9.
   Web of Science ®Google Scholar
• Estienne A, Portela VM, Choi Y, et al. The endogenous hydrogen sulfide generating system regulates ovulation. Free Radic Biol Med. 2019;138:43–52.
   PubMed Web of Science ®Google Scholar
• Nevoral J, Žalmanová T, Zámostná K, et al. Endogenously produced hydrogen sulfide is involved in porcine oocyte maturation in vitro. Nitric Oxide. 2015;51:24–35.
   PubMed Web of Science ®Google Scholar
• Wang K, Ahmad S, Cai M, et al. Dysregulation of hydrogen sulfide producing enzyme cystathionine γ-lyase contributes to maternal hypertension and placental abnormalities in preeclampsia. Circulation. 2013;127(25):2514–2522.
   PubMed Web of Science ®Google Scholar
• Lu L, Kingdom J, Burton GJ, et al. Placental stem villus arterial remodeling associated with reduced hydrogen sulfide synthesis contributes to human fetal growth restriction. Am J Pathol. 2017;187(4):908–920.
   PubMed Web of Science ®Google Scholar
• Filis P, Kind PC, Spears N. Implantation failure in mice with a disruption in phospholipase C beta 1 gene: lack of embryonic attachment, aberrant steroid hormone signalling and defective endocannabinoid metabolism. Mol Hum Reprod. 2013;19(5):290–301.
   PubMed Web of Science ®Google Scholar
• Zorrilla M, Yatsenko AN. The genetics of infertility: current status of the field. Curr Genet Med Rep. 2013;1(4):247–260.
   Google Scholar
• Rebecchi MJ, Pentyala SN. Structure, function, and control of phosphoinositide-specific phospholipase C. Physiol Rev. 2000;80(4):1291–1335.
   PubMed Web of Science ®Google Scholar
• Oliver KF, Wahl AM, Dick M, et al. Genomic analysis of spontaneous abortion in holstein heifers and primiparous cows. Genes (Basel). 2019;10(12):954.
   PubMed Web of Science ®Google Scholar
• Gholizadeh M, Esmaeili-Fard SM. Meta-analysis of genome-wide association studies for litter size in sheep. Theriogenology. 2022;180:103–112.
   PubMed Web of Science ®Google Scholar
• KLüPPEL M, Vallis KA, Wrana JL. A high-throughput induction gene trap approach defines C4ST as a target of BMP signaling. Mech Dev. 2002;118(1–2):77–89.
   PubMed Web of Science ®Google Scholar
• Tao L, He X, Jiang Y, et al. Genome-wide analyses reveal genetic convergence of prolificacy between goats and sheep. Genes (Basel). 2021;12(4):480.
   PubMed Web of Science ®Google Scholar
• KLüPPEL M, Wight TN, Chan C, et al. Maintenance of chondroitin sulfation balance by chondroitin-4-sulfotransferase 1 is required for chondrocyte development and growth factor signaling during cartilage morphogenesis. Development. 2005;132(17):3989–4003.
   PubMed Web of Science ®Google Scholar
• VON Mering C, Jensen LJ, Snel B, et al. STRING: known and predicted protein-protein associations, integrated and transferred across organisms. Nucleic Acids Res. 2005;33(Database issue):D433–7.
   PubMedGoogle Scholar
• Tao L, He XY, Wang FY, et al. Identification of genes associated with litter size combining genomic approaches in Luzhong mutton sheep. Anim Genet. 2021;52(4):545–549.
   PubMed Web of Science ®Google Scholar
• Cai D, Wang Z, Zhou Z, et al. Integration of transcriptome sequencing and whole genome resequencing reveal candidate genes in egg production of upright and pendulous-comb chickens. Poult Sci. 2023;102(4):102504.
   PubMed Web of Science ®Google Scholar
• Choi SG, Wang Q, Jia J, et al. Growth differentiation factor 9 (GDF9) forms an incoherent feed-forward loop modulating follicle-stimulating hormone β-subunit (FSHβ) gene expression. J Biol Chem. 2014;289(23):16164–16175.
   PubMed Web of Science ®Google Scholar
• Lyga S, Volpe S, Werthmann RC, et al. Persistent cAMP signaling by internalized LH receptors in ovarian follicles. Endocrinology. 2016;157(4):1613–1621.
   PubMed Web of Science ®Google Scholar
• Simmons HM, Ruis BL, Kapoor M, et al. Identification of NOM1, a nucleolar, eIF4A binding protein encoded within the chromosome 7q36 breakpoint region targeted in cases of pediatric acute myeloid leukemia. Gene. 2005;347(1):137–145.
   PubMed Web of Science ®Google Scholar
• Gunawardena SR, Ruis BL, Meyer JA, et al. NOM1 targets protein phosphatase I to the nucleolus. J Biol Chem. 2008;283(1):398–404.
   PubMed Web of Science ®Google Scholar
• Volodarsky M, Lichtig H, Leibson T, et al. CDC174, a novel component of the exon junction complex whose mutation underlies a syndrome of hypotonia and psychomotor developmental delay. Hum Mol Genet. 2015;24(22):6485–6491.
   PubMed Web of Science ®Google Scholar
• Selvaraju S, Swathi D, Ramya L, et al. Orchestrating the expression levels of sperm mRNAs reveals CCDC174 as an important determinant of semen quality and bull fertility. Syst Biol Reprod Med. 2021;67(1):89–101.
   PubMed Web of Science ®Google Scholar
• Middelbeek J, Clark K, Venselaar H, et al. The alpha-kinase family: an exceptional branch on the protein kinase tree. Cell Mol Life Sci. 2010;67(6):875–890.
   PubMed Web of Science ®Google Scholar
• Peleli M, Antoniadou I, Rodrigues-Junior DM, et al. Cystathionine gamma-lyase (CTH) inhibition attenuates glioblastoma formation. Redox Biol. 2023;64:102773.
   PubMed Web of Science ®Google Scholar
• Lechuga TJ, Qi QR, Magness RR, et al. Ovine uterine artery hydrogen sulfide biosynthesis in vivo: effects of ovarian cycle and pregnancy. Biol Reprod. 2019;100(6):1630–1636.
   PubMed Web of Science ®Google Scholar
• Chen DB, Feng L, Hodges JK, et al. Human trophoblast-derived hydrogen sulfide stimulates placental artery endothelial cell angiogenesis. Biol Reprod. 2017;97(3):478–489.
   PubMed Web of Science ®Google Scholar
• You X, Chen Z, Zhao H, et al. Endogenous hydrogen sulfide contributes to uterine quiescence during pregnancy. Reproduction. 2017;153(5):535–543.
   PubMed Web of Science ®Google Scholar
• Liang R, Yu WD, Du JB, et al. Localization of cystathionine beta synthase in mice ovaries and its expression profile during follicular development. Chin Med J (Engl). 2006;119(22):1877–1883.
   PubMed Web of Science ®Google Scholar
• Jeong W, Kim J, Ahn SE, et al. AHCYL1 is mediated by estrogen-induced ERK1/2 MAPK cell signaling and microRNA regulation to effect functional aspects of the avian oviduct. PLoS One. 2012;7(11):e49204.
   PubMed Web of Science ®Google Scholar
• Chmurzynska A, Seremak-Mrozikiewicz A, Malinowska AM, et al. Associations between folate and choline intake, homocysteine metabolism, and genetic polymorphism of MTHFR, BHMT and PEMT in healthy pregnant polish women. Nutr Diet. 2020;77(3):368–372.
   PubMed Web of Science ®Google Scholar
• Manabe N, Matsuda-Minehata F, Goto Y, et al. Role of cell death ligand and receptor system on regulation of follicular atresia in pig ovaries. Reprod Domest Anim. 2008;43 Suppl 2(s2):268–272.
   PubMedGoogle Scholar
• Inoue N, Matsuda F, Goto Y, et al. Role of cell-death ligand-receptor system of granulosa cells in selective follicular atresia in porcine ovary. J Reprod Dev. 2011;57(2):169–175.
   PubMed Web of Science ®Google Scholar
• Ledig S, RöPKE A, Wieacker P. Copy number variants in premature ovarian failure and ovarian dysgenesis. Sex Dev. 2010;4(4-5):225–232.
   PubMed Web of Science ®Google Scholar
• Filis P, Lannagan T, Thomson A, et al. Phospholipase C-beta1 signaling affects reproductive behavior, ovulation, and implantation. Endocrinology. 2009;150(7):3259–3266.
   PubMed Web of Science ®Google Scholar
• Böhm D, Schwegler H, Kotthaus L, et al. Disruption of PLC-beta 1-mediated signal transduction in mutant mice causes age-dependent hippocampal mossy fiber sprouting and neurodegeneration. Molecular Cellular Neurosci. 2002;21(4):584–601.
   PubMed Web of Science ®Google Scholar
• Ballester M, Molist J, Lopez-Bejar M, et al. Disruption of the mouse phospholipase C-beta1 gene in a beta-lactoglobulin transgenic line affects viability, growth, and fertility in mice. Gene. 2004;341:279–289.
   PubMed Web of Science ®Google Scholar
• Bhattacharyya S, Feferman L, Tobacman JK. Regulation of chondroitin-4-sulfotransferase (CHST11) expression by opposing effects of arylsulfatase B on BMP4 and Wnt9A. Biochim Biophys Acta. 2015;1849(3):342–352.
   PubMed Web of Science ®Google Scholar
• Oliveira-Ferrer L, Heßling A, Trillsch F, et al. Prognostic impact of chondroitin-4-sulfotransferase CHST11 in ovarian cancer. Tumour Biol. 2015;36(11):9023–9030.
   PubMedGoogle Scholar
• Farkas SA, Sorbe BG, Nilsson TK. Epigenetic changes as prognostic predictors in endometrial carcinomas. Epigenetics. 2017;12(1):19–26.
   PubMed Web of Science ®Google Scholar
• Wu P, Wang K, Zhou J, et al. GWAS on imputed whole-genome resequencing from genotyping-by-sequencing data for farrowing interval of different parities in pigs. Front Genet. 2019;10:1012.
   PubMed Web of Science ®Google Scholar