Advanced search
Publication Cover
Toxicology Methods Volume 11, 2001 - Issue 3
Journal homepage
10
Views
2
CrossRef citations to date
0
Altmetric
Research Article

DIFFERENCES IN THE DETECTION OF c-JUN/UBIQUITIN IMMUNOREACTIVE PROTEINS BY DIFFERENT c-JUN ANTIBODIES

J. Kato-Weinstein Pharmacology/Toxicology Program, College of Pharmacy, Washington State University, Pullman,Washington, USA
,
G. A. Orner Pharmacology/Toxicology Program, College of Pharmacy, Washington State University, Pullman,Washington, USA
,
B. D. Thrall Molecular Biosciences, Paci.c Northwest National Laboratory, Richland, Washington, USA
&
R. J. Bull Molecular Biosciences, Paci.c Northwest National Laboratory, Richland, Washington, USACorrespondenceE-mail: [email protected]
Pages 189-207 | Published online: 30 Sep 2008

  • Papavassiliou, A. G., Treier, M., and Bohmann, D. 1995. Intramolecular signal transduction in c-Jun. EMBO J. 14:2014-2019.
  • Richmond, R. E., DeAngelo, A. B., Potter, C. L., and Daniel, F. B. 1991. The role of hyperplastic nodules in dichloroacetic acid-induced hepatocarcinogenesis in B6C3F1 male mice. Carcinogenesis 12:1383-1387.
  • Richmond, R. E., Carter, J. H., Carter, H. W., Daniel, F. B., and DeAngelo, A. B. 1995. Immunohistochemical analysis of dichloroacetic acid (DCA)-induced hepatocarcinogenesis in male Fischer (F344) rats. Cancer Lett. 92:67-76.
  • Stauber, A. J., and Bull, R. J. 1997. Differences in phenotype and cell replicative behavior of hepatic tumors induced by dichloroacetate (DCA) and trichloroacetate (TCA). Toxicol. Appl. Pharmacol. 144:235-246.
  • Ribes, G., Valette, G., Valette, J. F., and Loubatieres-Mariani, M. M. 1981. Sodium 2-chloropropionate: its effects on experimental hyperlactatemia in the dog. J. Pharmacol. Exp. Ther. 216:172-175.
  • Angel, P., and Karin, M. 1991. The role of Jun, Fos and the AP-I complex in cell-proliferation and transformation. Biochim. Biophys. Ada 1072:129-157.
  • Karin, M., and Smeal, T. 1992. Control of transcription factors by signal transduction pathways: the beginning of the end. Trends Biochem. Sci. 17:418-422.
  • Hibi, M., Lin, A., Smeal, T., Minden, A., and Karin, M. 1993. Identification of an oncoproteinand UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev. 7:2136-2148.
  • Derjjard, B., Hibi, M., Wu, I. H., Barrett, T., Su, B., Deng, T., Karin, M., and Davis, R. J. 1994. JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76:1026-1037.
  • Fuchs, S. Y., Dolan, L., Davis, R. J., and Ronai, Z. 1996. Phosphorylation-dependent targeting of c-Jun ubiquitination by Jun N-kinase. Oncogene 13:1631-1636.
  • Musti, A. M., Treier, M., and Bohmann, D. 1997. Reduced ubiquitin-dependent degradation of c-Jun after phosphorylation by MAP kinases. Science 276:400-402.
  • Lin, A., Frost, J., Deng, T., Smeal, T., al-Alwai, N., Kikkawa, U., Hunter, T., Brenner, D., and Karin, M. 1992. Casein kinase II is a negative regulator of c-Jun DNA binding and AP-1 activity [published erratum appears in Cell 1992 71:following 886]. Cell 70:777-789.
  • Boyle, W. J., Smeal, T., Deflze, L. H., Angel, P., Woodgett, J. R., Karin, M., and Hunter, T. 1991. Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity. Cell 64:673-684.
  • Angel, P., Allegretto, E. A., Okino, S. T., Hattori, K., Boyle, W. J., Hunter, T., et al. 1988. Oncogene Jun encodes a sequence-specific trans-activator similar to AP-1. Nature 332:166-171.
  • Haas, A. L., and Bright, P. M. 1986. The immunochemical detection and quantitation of intracellular ubiquitin-protein conjugates. J. BM. Chem. 260:12464-12473.
  • Bernstein, L. R., Ben-Ari, E. T., Simek, S. L., and Colburn, N. H. 1991. Gene regulation and genetic susceptibility to neoplastic transformation: AP-1 and p80 expression in JB6 cells. Environ. Health Perspect. 93:111-119.
  • Rana, B., Mischoulon, D., Xie, Y, Bucher, N. L., and Farmer, S. R. 1994. Cell-extracellular matrix interactions can regulate the switch between growth and differentiation in rat hepatocytes : reciprocal expression of C/EBP alpha and immediate-early growth response transcription factors. MoI. Cell Biol. 14:6868-6869.
  • Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-686.
  • Towbin, H., Staehelin, T., and Gordon, J. 1979. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. NaU. Acad. Sci. USA 76:4360-4364.
  • Tanno, K., and Aoki, Y 1996. Phosphorylation of c-Jun stimulated in primary cultured rat liver parenchymal cells by a coplanar polychlorinated biphenyl. Biochem. J. 313:863-866.
  • Angel, P., Hattori, K., Smeal, T., and Karin, M. 1988. The Jun proto-oncogene is positively autoregulated by its product, Jun/AP-1. CM 66:876-886.
  • Ben-Ari, E. T., Bernstein, L. R., and Colbum, N. H. 1992. Differential c-Jun expression in response to tumor promoters in JB6 cells sensitive or resistant to neoplastic transformation. MoI. Carcinog. 6:62-74.
  • Black, E. J., Street, A. J., and Gillespie, D. A. 1991. Protein phosphatase 2A reverses phosphorylation of c-Jun specified by the delta domain in vitro: correlation with oncogenic activation and deregulated transactivation activity of v-Jun. Oncogene 6:1949-1968.
  • Hermida-Matsumoto, M. L., Chock, P. B., Curran, T, and Yang, D. C. 1996. Ubiquitinylation of transcription factors c-Jun and c-Fos using reconstituted ubiquitinylating enzymes. J. Biol. Chem. 271:4930-4936.
  • Binetruy, B., Smeal, T., and Karin, M. 1991. Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain. Nature 361:122-127.
  • Smeal, T, Binetruy, B., Mercola, D. A., Birrer, M., and Karin, M. 1991. Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73. Nature 364:494-496.
  • Schlesinger, D. H., Goldstein, G., and Niall, H. D. 1976. The complete amino acid sequence of ubiquitin, an adenylate cyclase stimulating polypeptide probably universal in living cells. Biochemistry 14:2214-2218.
  • Clerk, A., and Sugden, P. H. 1997. Cell stress-induced phosphorylation of ATF2 and c-Jun transcription factors in rat ventricular myocytes. Biochem. J. 326:801-810.
  • Mimnaugh, E. G., Bonvini, P., and Neckers, L. 1999. The measurement of ubiquitin and ubiquitinated proteins. Electrophoresis 20:418-428.
  • Adler, V., Yin, Z., Fuchs, S. Y., Benezra, M., Rosario, L., Tew, K. D., Pincus, M. R., Sardana, M., Henderson, C. J., Wolf, C. R., Davis, R. J., and Ronai, Z. 1999. Regulation of JNK signaling by GSTp. EMBO J. 18:1321-1334.
  • Woodgett, J. R. 1991. A common denominator linking glycogen metabolism, nuclear oncogenes and development. Trends Biochem. Sci. 16:177-178.
  • Cohen, P., and Hardie, D. G. 1991. The actions of cyclic AMP on biosynthetic processes are mediated indirectly by cyclic AMP-dependent protein kinase. Biochim. Biophys. Acta 1094:292299.
  • Kate-Weinstein, J., Lingohr, M. K., Orner, G. A., Thrall, B. D., and Bull, R. J. 1998. Effects of dichloroacetate on glycogen metabolism in B6C3F1 mice. Toxicology 130:141-154.
  • Ryder, K., and Nathans, D. 1988. Induction of protooncogene c-Jun by serum growth factors. Proc. Natl. Acad. Sci. USA 85:8464-8467.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.