43
Views
24
CrossRef citations to date
0
Altmetric
Research Article

CYTOTOXICITY ASSESSMENT OF WHOLE SMOKE AND VAPOR PHASE OF MAINSTREAM AND SIDESTREAM CIGARETTE SMOKE FROM THREE KENTUCKY REFERENCE CIGARETTES

Pages 177-190 | Published online: 30 Sep 2008

REFERENCES

  • Doolittle DJ, Lee CJ, Ivett J L, et al. Comparative studies on the genotoxic activity of mainstream smoke condensate from cigarettes which burn or only heat tobacco. Environ Mol Mutagen. 1990;15:93–105.
  • Doolittle DJ, Lee CK, Ivett J L, et al. Genetic toxicology studies comparing the activity of sidestream smoke from cigarettes which burn or only heat tobacco. Mutat Res. 1990;240:59–72.
  • DeMarini DM. Genotoxicity of tobacco smoke and tobacco smoke condensate. Mutat Res. 1983;114:59–89.
  • Bombick DW, Doolittle DJ. The role of chemical structure and cell type in the cytotoxicity of low molecular weight aldehydes and pyridines. In Vitro Toxicol., 1995;8:349–356.
  • Grafstrom RC, Willey JC, Sundqvist K, Harris CC. Pathobiological effects of tobacco smoke-related aldehydes in cultured human bronchial epithelial cells. In: Hoffmann D, Harris CC, eds. Banbury Report 23: Mechanism s in Tobacco Carcinogenesis. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory; 19 86:273–285.
  • Harris CC, Willey JC, Saladino AJ, Grafstrom RC. Effects of tumor promoters, aldehydes, peroxides and tobacco smoke condensate on growth and differentiation of cultured normal and transformed human bronchial cells. In: Mass M et al, eds. Cancer of the Respiratory Tract: Predisposing Factors. New York: Plenum; 1985:159.
  • Saladino AJ, Willey JC, Lechner JE, Grafstrom RC, LaVeck M, Harris CC. Effects of formaldehyde, acetaldehyde, benzoyl peroxide and hydrogen peroxide on cultured normal human bronchial epithelial cells. Cancer Res. 1985;45:2522.
  • Bombick DW, Ayres PH, Nelson PR, et al. Assessment of the biological activity of mainstream or environmental tobacco smoke (ETS) using a cellular smoke exposure technique. Environ Mol Mu tagen. 1991;17:11.
  • Bombick DW, Putnam K, Corn J, Ayres PH, Doolittle DJ. Cytotoxicity assessment of smoke from test cigarettes with a novel carbon filter. The Toxicologist. 1995;15:125 (abstract 663).
  • Bombick DW, Putnam K, Bombick BR, Morgan WT, Ayres PH, Doolittle DJ. In vitro assessment of biological activity of mainstream smoke from cigarettes which burn or primarily heat tobacco. Int Toxicol. 1995;7: abstract 73-P-19.
  • Borenfreund E, Puerner JA. Toxicity determined in vitro by morphological alterations and neutral red absorption. Toxicol Lett. 1985;24:119–124.
  • Borenfreund E, Puerner JA. A simple quantitative procedure using monolayer cultures for cytotoxicity assays (HTD/NR-90). J Tissue Culture Methods. 1984;65:5 5–63.
  • Bombick DW, Doolittle DJ. The effect of cell type on chemical toxicity in the neutral red cytotoxicity assay. The Toxicologist. 1992;12:373 (abstract 1460).
  • Tsao MS, Smith JD, Nelson KG, Grisham JW. A diploid epithelial cell line from normal adult rat liver with phenotypic properties of oval cells. Exp Cell Res. 1984;154:38–52.
  • Baumgartner H, Coggins CRE. Description of a continuous-smoking inhalation machine for exposing small animals to tobacco smoke. Beitr Tabakforsh Int. 1980;10:169–174.
  • Cannon WC, Blanton EF, McDonald KE. The flow past chamber: an improved nose-only exposure system for rodents. Am H yg Assoc J. 19893;44:923–928.
  • Ayres PH, Mosberg AT, Coggins CRE. Modernization of nose-only smoking machines for use in animal inhalation studies. J Am Coll Toxicol. 1990;9:441 –446.
  • Steel RGD, Torrie JH. Principles and Procedures of Statistics: A Biometrical Approach, 2d ed. New York: McGraw-Hill; 1980:183–185.
  • Gad S, Weil CS. Statistics and Experimental Design for Toxicologists. Caldwell, NJ: Telford; 1986:93–110.
  • Salsburg DS. Statistics for Toxicologists. New York: Dekker; 1986:3–62.
  • Finney DJ. Probit Analysis. New York: Cambridge University Press; 1971:20–49.
  • Guerin MR, Higgins CE, Griest WH. The analysis of the particulate and vapor phases of tobacco smoke. In: ONeil IK, Brunnemann KD, Dodet B, Hoffmann D, eds. Environmental Carcinogens: Methods of Analysis and Exposure Measurement, Vol. 9, Passive Smoking. IARC Sci.; 1987;No. 81:115–139.
  • Stedman RL. The chemical composition of tobacco and tobacco smoke. Chem Rev. 1968;68:1 53–207.
  • R. J. Reynolds Tobacco Company. Ch em ical and Biological S tudies on New Cigarette Prototyp es That Heat Instead of Burn Tobacco. Winston-Salem, NC: R. J. Reynolds Tobacco Company. 1988:117–180.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.