Effect of hesperetin on systemic inflammation and hepatic injury after blunt chest trauma in rats

References

• Ahmadi A, Hassandarvish P, Lani R, Yadollahi P, Jokar A, Bakar SA, Zandi K. 2016. Inhibition of chikungunya virus replication by hesperetin and naringenin. Roy Soc Chem Adv. 6:69421–69430.
   Web of Science ®Google Scholar
• Aranganathan S, Nalini N. 2013. Antiproliferative efficacy of hesperetin (citrus flavanoid) in 1, 2‐dimethylhydrazine‐induced colon cancer. Phytother Res. 27:999–1005.
   PubMed Web of Science ®Google Scholar
• Askin Esen Hasturk M, Yilmaz ER, Turkoglu E, Kertmen H, Horasanli B, Hayirli N, Erguder IB, Evirgen O. 2015. Therapeutic evaluation of interleukin 1-beta antagonist anakinra against traumatic brain injury in rats. Ulus Trav Acil Cerrahi Derg. 21:1–8.
   PubMed Web of Science ®Google Scholar
• Aswar M, Kute P, Mahajan S, Mahajan U, Nerurkar G, Aswar U. 2014. Protective effect of hesperetin in rat model of partial sciatic nerve ligation induced painful neuropathic pain: an evidence of anti-inflammatory and anti-oxidative activity. Pharmacol Biochem Behav. 124:101–107.
   PubMed Web of Science ®Google Scholar
• Bai X, Yang P, Zhou Q, Cai B, Buist‐Homan M, Cheng H, Jiang J, Shen D, Li L, Luo X. 2017. The protective effect of the natural compound hesperetin against fulminant hepatitis in vivo and in vitro. Br J Pharmacol. 174:41–56.
   PubMed Web of Science ®Google Scholar
• Bıçakçı N, Karaboğa İ, Dökmeci A, Güzel S, Fidanol Erboğa Z. 2019. Cardioprotective effect of caffeic acid phenethyl ester on cardiac contusion following blunt chest trauma in rats. Biotech Histochem. 1-7. DOI: 10.1080/10520295.2019.1586999.
   Google Scholar
• Esposito E, Cuzzocrea S. 2009. TNF-alpha as a therapeutic target in inflammatory diseases, ischemia-reperfusion injury and trauma. Curr Med Chem. 16:3152–3167.
   PubMed Web of Science ®Google Scholar
• Flierl MA, Perl M, Rittirsch D, Bartl C, Schreiber H, Fleig V, Schlaf G, Liener U, Brueckner UB, Gebhard F. 2008. The role of C5a in the innate immune response after experimental blunt chest trauma. Shock. 29:25–31.
   PubMed Web of Science ®Google Scholar
• Garg A, Garg S, Zaneveld L, Singla A. 2001. Chemistry and pharmacology of the citrus bioflavonoid hesperidin. Phytother Res. 15:655–669.
   PubMed Web of Science ®Google Scholar
• González-Gallego J, García-Mediavilla MV, Sánchez-Campos S, Tuñón MJ. 2018. Anti-inflammatory, immunomodulatory, and prebiotic properties of dietary flavonoids. polyphenols: prevention and treatment of human disease. Elsevier, Academic Press, Cambridge, MA. p. 327–345.
   Google Scholar
• Guardia T, Rotelli AE, Juarez AO, Pelzer LE. 2001.Anti-inflammatory properties of plant flavonoids. Effects of rutin, quercetin and hesperidin on adjuvant arthritis in rat. Il Farm. 56:683–687.
   Google Scholar
• Hensler T, Sauerland S, Bouillon B, Raum M, Rixen D, Helling H-J, Andermahr J, Neugebauer EA. 2002. Association between injury pattern of patients with multiple injuries and circulating levels of soluble tumor necrosis factor receptors, interleukin-6 and interleukin-10, and polymorphonuclear neutrophil elastase. J Traum Acute Care Surg. 52:962–970.
   Google Scholar
• Hietbrink F, Koenderman L, Rijkers GT, Leenen LP. 2006. Trauma: the role of the innate immune system. World J Emerg Surg 1:15.
   PubMedGoogle Scholar
• Hinz M, Scheidereit C. 2014. The IκB kinase complex in NF‐κB regulation and beyond. EMBO Rept. 15:46–61.
   PubMed Web of Science ®Google Scholar
• Hsu S-M, Raine L, Fanger H. 1981. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. J Histochem Cytochem. 29:577–580.
   PubMed Web of Science ®Google Scholar
• Kaiser K, Kovtun A, Prystaz K, Haffner-Luntzer M, Waetzig GH, Rose-John S, Ignatius A. 2018. Inhibition of interleukin-6 trans-signalling improves fracture healing after trauma. J Bone Joint Surg Br. 100: 66.
   Google Scholar
• Kara S, Gencer B, Karaca T, Tufan HA, Arikan S, Ersan I, Karaboga I, Hanci V. 2014. Protective effect of hesperetin and naringenin against apoptosis in ischemia/reperfusion-induced retinal injury in rats. Sci World J. 2014:1–8.
   Google Scholar
• Karaboga I. 2018. Caffeic acid phenethyl ester (CAPE) suppresses systemic inflammation in rat trauma model. J Apitherapy. 3:31–35.
   Google Scholar
• Karaboğa İ, Ovalı M, Yılmaz A, Alpaslan M. 2018. Gastroprotective effect of apricot kernel oil in ethanol-induced gastric mucosal injury in rats. Biotech Histochem. 93:601–607.
   PubMed Web of Science ®Google Scholar
• Knöferl MW, Liener UC, Seitz DH, Perl M, Brückner UB, Kinzl L, Gebhard F. 2003. Cardiopulmonary, histological, and inflammatory alterations after lung contusion in a novel mouse model of blunt chest trauma. Shock. 19:519–525.
   PubMed Web of Science ®Google Scholar
• Knöferl MW, Liener UC, Perl M, Brückner UB, Kinzl L, Gebhard F. 2004. Blunt chest trauma induces delayed splenic immunosuppression. Shock. 22:51–56.
   PubMed Web of Science ®Google Scholar
• Kumar B, Gupta SK, Srinivasan B, Nag TC, Srivastava S, Saxena R, Jha KA. 2013. Hesperetin rescues retinal oxidative stress, neuroinflammation and apoptosis in diabetic rats. Microvasc Res. 87:65–74.
   PubMed Web of Science ®Google Scholar
• Li R, Cai L, Xie X-f, Peng L, Wu T-n, Li J. 2013. 7, 3′-Dimethoxy hesperetin inhibits inflammation by inducing synovial apoptosis in rats with adjuvant-induced arthritis. Immunopharmacol Immunotoxicol. 35:139–146.
   PubMed Web of Science ®Google Scholar
• Miler M, Živanović J, Ajdžanović V, Oreščanin-Dušić Z, Milenković D, Konić-Ristić A, Blagojević D, Milošević V, Šošić-Jurjević B. 2016. Citrus flavanones naringenin and hesperetin improve antioxidant status and membrane lipid compositions in the liver of old-aged Wistar rats. Exp Gerontol. 84:49–60.
   PubMed Web of Science ®Google Scholar
• Mörs K, Braun O, Wagner N, Auner B, Voth M, Störmann P, Wutzler S, Marzi I, Relja B. 2016. Influence of gender on systemic IL-6 levels, complication rates and outcome after major trauma. Immunobiology. 221:904–910.
   PubMed Web of Science ®Google Scholar
• Nacar A, Karaboga I, Okuyan HM, Sefil NK, Nacar E, Motor S, Akkücük S, Ozkan OV. 2015. Investigation of the protective effect of erdosteine against cyclosporine-induced injury in rat liver with histological and biochemical methods. Turk J Med Sci. 45:1390–1395.
   PubMed Web of Science ®Google Scholar
• Pari L, Shagirtha K. 2012. Hesperetin protects against oxidative stress related hepatic dysfunction by cadmium in rats. Exp Toxicol Pathol. 64:513–520.
   PubMedGoogle Scholar
• Perl M, Gebhard F, Braumüller S, Tauchmann B, Brückner UB, Kinzl L, Knöferl MW. 2006. The pulmonary and hepatic immune microenvironment and its contribution to the early systemic inflammation following blunt chest trauma. Crit Care Med. 34:1152–1159.
   PubMed Web of Science ®Google Scholar
• Polat F, Karaboğa İ. 2018. Immunohistochemical examination of anti-inflammatory and anti-apoptotic effects of hesperetin on trinitrobenzene sulfonic acid induced colitis in rats. Biotech Histochem. 94: 151–158.
   PubMed Web of Science ®Google Scholar
• Polat FR, Karaboga I, Polat MS, Erboga Z, Yilmaz A, Güzel S. 2018. Effect of hesperetin on inflammatory and oxidative status in trinitrobenzene sulfonic acid-induced experimental colitis model. Cell Mol Biol (Noisy-le-Grand, France). 64:58–65.
   PubMed Web of Science ®Google Scholar
• Raghavendran K, Davidson BA, Helinski JD, Marschke CJ, Manderscheid P, Woytash JA, Notter RH, Knight PR. 2005. A rat model for isolated bilateral lung contusion from blunt chest trauma. Anesth Analges. 101:1482–1489.
   PubMed Web of Science ®Google Scholar
• Recknagel S, Bindl R, Kurz J, Wehner T, Ehrnthaller C, Knöferl MW, Gebhard F, Huber‐Lang M, Claes L, Ignatius A. 2011. Experimental blunt chest trauma impairs fracture healing in rats. J Orthop Res. 29:734–739.
   PubMed Web of Science ®Google Scholar
• Sakran JV, Greer SE, Werlin E, McCunn M. 2012. Care of the injured worldwide: trauma still the neglected disease of modern society. Scand Trauma Resusc Emer Med 20: 64. doi: 10.1186/1757-7241-20-64, PMID: 22980446.
   Google Scholar
• Samie A, Sedaghat R, Baluchnejadmojarad T, Roghani M. 2018. Hesperetin, a citrus flavonoid, attenuates testicular damage in diabetic rats via inhibition of oxidative stress, inflammation, and apoptosis. Life Sci. 210:132–139.
   PubMed Web of Science ®Google Scholar
• Shagirtha K, Bashir N, MiltonPrabu S. 2017. Neuroprotective efficacy of hesperetin against cadmium induced oxidative stress in the brain of rats. Toxicol Indus Health. 33:454–468.
   PubMed Web of Science ®Google Scholar
• Smina T, Mohan A, Ayyappa K, Sethuraman S, Krishnan U. 2015. Hesperetin exerts apoptotic effect on A431 skin carcinoma cells by regulating mitogen activated protein kinases and cyclins. Cell Mol Biol. 61:92–99.
   PubMed Web of Science ®Google Scholar
• Sordi R, Chiazza F, Johnson FL, Patel NS, Brohi K, Collino M, Thiemermann C. 2015. Inhibition of IκB kinase attenuates the organ injury and dysfunction associated with hemorrhagic shock. Mol Med 21:563–575.
   PubMed Web of Science ®Google Scholar
• Stalp M, Seekamp A. 1999. Ischemia-reperfusion directly increases pulmonary endothelial permeability in vitro. Shock 11:259–263.
   PubMed Web of Science ®Google Scholar
• Taniguchi T, Koido Y, Aiboshi J, Yamashita T, Suzaki S, Kurokawa A. 1999. The ratio of interleukin-6 to interleukin-10 correlates with severity in patients with chest and abdominal trauma. Am J Emer Med. 17:548–551.
   PubMed Web of Science ®Google Scholar
• Torun AÇ, Tütüncü Ş. 2019. Assessing the therapeutic effect of resveratrol in heart failure following blunt chest trauma and the potential role of endocan as a biomarker of inflammation using rats. Ulus Travma Acil Cerrahi Derg. 25:343–349.
   PubMed Web of Science ®Google Scholar
• Wagner N, Dieteren S, Franz N, Köhler K, Mörs K, Nicin L, Schmidt J, Perl M, Marzi I, Relja B. 2018. Ethyl pyruvate ameliorates hepatic injury following blunt chest trauma and hemorrhagic shock by reducing local inflammation, NF-kappaB activation and HMGB1 release. PloS One. 13(2):e0192171.
   PubMed Web of Science ®Google Scholar
• Wu X-J, Xia Z-Y, Wang L-L, Luo T, Zhan L-Y, Meng Q-T, Song X-M. 2012. Effects of penehyclidine hydrochloride on pulmonary contusion from blunt chest trauma in rats. Injury. 43:232–236.
   PubMed Web of Science ®Google Scholar
• Wu X, Song X, Li N, Zhan L, Meng Q, Xia Z. 2013. Protective effects of dexmedetomidine on blunt chest trauma-induced pulmonary contusion in rats. J Traum Acute Care Surg. 74:524–530.
   PubMed Web of Science ®Google Scholar