257
Views
0
CrossRef citations to date
0
Altmetric
Articles

Effects of noopept on ocular, pancreatic and renal histopathology in streptozotocin induced prepubertal diabetic rats

ORCID Icon, ORCID Icon, ORCID Icon &

References

  • Ali MK, Siegel KR, Chandrasekar E, Tandon N, Montoya PA, Mbanya J-C, Chan J, Zhang P, Narayan KM. 2017. Chapter 12- Diabetes: an update on the pandemic and potential solutions. In: Prabhakaran D, Anand S, Gaziano T, Mbanya J, Wu Y, and Nugent R, editors. Disease control priorities (Volume 5): Cardiovascular, respiratory, and related disorders. 3rd ed. Washington, DC: International Bank for Reconstruction and Development/World Bank. https://www.ncbi.nlm.nih.gov/books/NBK525150/.
  • Arroyo P, Ho BS, Sau L, Kelle ST, Thackray VG. 2019. Letrozole treatment of pubertal female mice results in activational effects on reproduction, metabolism and the gut microbiome. PloS One. 14:e0223274. doi:10.1371/journal.pone.0223274
  • Atkinson MA, Eisenbarth GS, Michels AW. 2014. Type 1 diabetes. Lancet. 383:69–82. doi:10.1016/S0140-6736(13)60591-7
  • Cho YH, Craig ME, Donaghue KC. 2014. Puberty as an accelerator for diabetes complications. Ped Diabetes. 15:18–26. doi:10.1111/pedi.12112
  • Chowdhury S. 2015. Puberty and type 1 diabetes. Ind J Endocrinol Metab. 19:S51–S54. doi:10.4103/2230-8210.155402
  • Coppolino G, Leporini C, Rivoli L, Ursini F, di Paola ED, Cernaro V, Arturi F, Bolignano D, Russo E, De Sarro G. 2018. Exploring the effects of DPP-4 inhibitors on the kidney from the bench to clinical trials. Pharmacol Res. 129:274–294. doi:10.1016/j.phrs.2017.12.001
  • Dabelea D, Mayer-Davis EJ, Saydah S, Imperatore G, Linder B, Divers J, Bell R, Badaru A, Talton JW, Crume T. 2014. Prevalence of type 1 and type 2 diabetes among children and adolescents from 2001 to 2009. J Am Med Assoc. 311:1778–1786. doi:10.1001/jama.2014.3201
  • Dabelea D, Stafford JM, Mayer-Davis EJ, D’Agostino R, Dolan L, Imperatore G, Linder B, Lawrence JM, Marcovina SM, Mottl AK. 2017. Association of type 1 diabetes vs. type 2 diabetes diagnosed during childhood and adolescence with complications during teenage years and young adulthood. J Am Med Assoc. 317:825–835. doi:10.1001/jama.2017.0686
  • Dehdashtian E, Mehrzadi S, Yousefi B, Hosseinzadeh A, Reiter RJ, Safa M, Ghaznavi H, Naseripour M. 2018. Diabetic retinopathy pathogenesis and the ameliorating effects of melatonin; involvement of autophagy, inflammation and oxidative stress. Life Sci. 193:20–33. doi:10.1016/j.lfs.2017.12.001
  • Dietrich N, Kolibabka M, Busch S, Bugert P, Kaiser U, Lin J, Fleming T, Morcos M, Klein T, Schlotterer A. 2016. The DPP4 inhibitor linagliptin protects from experimental diabetic retinopathy. PloS One. 11:e0167853. doi:10.1371/journal.pone.0167853
  • Dresler M, Sandberg A, Bublitz C, Ohla K, Trenado C, Mroczko-Wasowicz A, Kühn S, Repantis D. 2018. Hacking the brain: dimensions of cognitive enhancement. ACS Chem Neurosci. 10:1137–1148. doi:10.1021/acschemneuro.8b00571
  • Düzova H, Nazıroğlu M, Çiğ B, Gürbüz P, Akatlı AN. 2021. Noopept attenuates diabetes-mediated neuropathic pain and oxidative hippocampal neurotoxicity via inhibition of trpv1 channel in rats. Mol Neurobiol. 58:5031–5051. doi:10.1007/s12035-021-02478-8
  • Elks CE, Ong KK, Scott RA, Van Der Schouw YT, Brand JS, Wark PA, Amiano P, Balkau B, Barricarte A, Boeing H. 2013. Age at menarche and type 2 diabetes risk: the EPIC-Interact study. Diabetes Care. 36:3526–3534. doi:10.2337/dc13-0446
  • Fan Y-Y, Kobori H, Nakano D, Hitomi H, Mori H, Masaki T, Sun Y-X, Zhi N, Zhang L, Huang W. 2013. Aberrant activation of the intrarenal renin-angiotensin system in the developing kidneys of type 2 diabetic rats. Horm Metab Res. 45:338–343. doi:10.1055/s-0032-1331256
  • Graves LE, Donaghue KC. 2019. Management of diabetes complications in youth. Ther Adv Endocrinol Metab. 10:2042018819863226. doi:10.1177/2042018819863226
  • Gul Baykalir B, Ciftci O, Cetin A, Basak Turkmen N. 2018. The protective effect of fish oil against cisplatin induced eye damage in rats. Cutan Ocular Toxicol. 37:151–156. doi:10.1080/15569527.2017.1361438
  • Gürbüz P, Düzova H, Yildiz A, Çakan P, Kaya GB, Bağ HGG, Durhan M, Gül CC, Taşlidere AÇ. 2019. Effects of noopept on cognitive functions and pubertal period in rats with diabetes. Life Sci. 233:116698. doi:10.1016/j.lfs.2019.116698
  • Harjutsalo V, Maric-Bilkan C, Forsblom C, Groop P-H, Group FS. 2016. Age at menarche and the risk of diabetic microvascular complications in patients with type 1 diabetes. Diabetologia. 59:472–480. doi:10.1007/s00125-015-3816-0
  • Heng L, Comyn O, Peto T, Tadros C, Ng E, Sivaprasad S, Hykin P. 2013. Diabetic retinopathy: pathogenesis, clinical grading, management and future developments. Diabetic Med. 30:640–650. doi:10.1111/dme.12089
  • Hsu Y-H, Chen Y-C, Chen Y-W, Chiu T-H, Kuo Y-T, Chen C-H. 2020. Far-infrared radiation prevents decline in β-cell mass and function in diabetic mice via the mitochondria-mediated sirtuin1 pathway. Metabolism. 104:154143. doi:10.1016/j.metabol.2020.154143
  • Jenkins AJ, Joglekar MV, Hardikar AA, Keech AC, O’neal DN, Januszewski AS. 2015. Biomarkers in diabetic retinopathy. Rev Diabetic Stud. 12:159–195. doi:10.1900/RDS.2015.12.159
  • Jigheh ZA, Haghjo AG, Argani H, Roshangar L, Rashtchizadeh N, Sanajou D, Ahmad SNS, Rashedi J, Dastmalchi S, Abbasi MM. 2019. Empagliflozin alleviates renal inflammation and oxidative stress in streptozotocin-induced diabetic rats partly by repressing HMGB1-TLR4 receptor axis. Iran J Basic Med Sci. 22:384–390. doi:10.22038/ijbms.2019.31788.7651
  • Karahan F (2015). Erkek sıçanlarda poliklorlu bifenillerin (Aroklor 1254) neden olduğu reproduktif hasara karşı tetrandrinin koruyucu etkilerinin araştırılması [ Master’s thesis]. İnönü Üniversitesi Sağlık Bilimleri Enstitüsü. https://tez.yok.gov.tr/UlusalTezMerkezi/tezSorguSonucYeni.jsp.
  • Katsuda Y, Sasase T, Tadaki H, Mera Y, Motohashi Y, Kemmochi Y, Toyoda K, Kakimoto K, Kume S, Ohta T. 2015. Contribution of hyperglycemia on diabetic complications in obese type 2 diabetic SDT fatty rats: effects of SGLT inhibitor phlorizin. Exp Anim. 64:161–169. doi:10.1538/expanim.14-0084
  • Kelsey MM, Zeitler PS. 2016. Insulin resistance of puberty. Curr Diabetes Rep. 16:1–6. doi:10.1007/s11892-016-0751-5
  • Khadilkar A, Oza C. 2022. Glycaemic control in youth and young adults: challenges and solutions. Diabetes Metab Syndr Obes Targ Ther. 15:121–129. doi:10.2147/DMSO.S304347
  • Kitada M, Koya D. 2021. Autophagy in metabolic disease and ageing. Nat Rev Endocrinol. 17:647–661. doi:10.1038/s41574-021-00551-9
  • Koffi Kouame AIP, Akang EN, Moodley R, Naidu EC, Azu OO. 2019. Histological and biochemical effects of Cinnamomum cassia nanoparticles in kidneys of diabetic Sprague-Dawley rats. Bos J Basic Med Sci. 19:138–145. doi:10.17305/bjbms.2019.3481
  • Li L, Li Y-L, Zhou Y-F, Ge Z-Y, Wang L-L, Li Z-Q, Guo Y-J, Jin L, Ren Y, Liu J-X. 2017. Jiangtang Xiaozhi Recipe (降糖消脂方) prevents diabetic retinopathy in streptozotocin-induced diabetic rats. Chin J Integ Med. 23:425–432. doi:10.1007/s11655-016-2595-x
  • Lind M, Pivodic A, Svensson A-M, Ólafsdóttir AF, Wedel H, Ludvigsson J. 2019. HbA1c level as a risk factor for retinopathy and nephropathy in children and adults with type 1 diabetes: Swedish population based cohort study. Br Med J. 366:l4894. doi:10.1136/bmj.l4894
  • Lytvyn Y, Bjornstad P, Pun N, Maahs DM, Perkins B, Cherney DZ. 2016. New and old agents in the management of diabetic nephropathy. Curr Opin Nephrol Hypertens. 25:232–239. doi:10.1097/MNH.0000000000000214
  • Marcovecchio M, Tossavainen P, Dunger D. 2010. Prevention and treatment of microvascular disease in childhood type 1 diabetes. Br Med Bull. 94:145–164. doi:10.1093/bmb/ldp053
  • Matsui T, Nakashima S, Nishino Y, Ojima A, Nakamura N, Arima K, Fukami K, Okuda S, Yamagishi S-I. 2015. Dipeptidyl peptidase-4 deficiency protects against experimental diabetic nephropathy partly by blocking the advanced glycation end products-receptor axis. Lab Invest. 95:525–533. doi:10.1038/labinvest.2015.35
  • Mellado-Gil JM, Cobo-Vuilleumier N, Gauthier BR. 2012. Islet β-cell mass preservation and regeneration in diabetes mellitus: four factors with potential therapeutic interest. (Corrigendum to “Islet β-cell mass preservation and regeneration in diabetes mellitus: four factors with potential therapeutic interest.” J Transpl. 2019). J transpl. 2012. Article ID 230870. doi:10.1155/2019/3281921
  • Öberg D, Salemyr J, Örtqvist E, Juul A, Bang P. 2018. A longitudinal study of serum insulin‐like growth factor‐i levels over 6 years in a large cohort of children and adolescents with type 1 diabetes mellitus: a marker reflecting diabetic retinopathy. Ped Diabetes. 19:972–978. doi:10.1111/pedi.12681
  • Oguntibeju OO. 2019. Type 2 diabetes mellitus, oxidative stress and inflammation: examining the links. Int J Physiol Pathophysiol Pharmacol. 11:45–63.
  • Ostrovskaya R, Gudasheva T, Voronina T, Seredenin S. 2002. The original novel nootropic and neuroprotective agent Noopept. Eks Klin Farmakol. 65:66–72.
  • Ostrovskaya R, Ozerova I, Gudascheva T, Kapitsa I, Ivanova E, Voronina T, Seredenin S. 2013. Efficiency of noopept in streptozotocin-induced diabetes in rats. Bull Exp Biol Med. 154:334–338. doi:10.1007/s10517-013-1944-4
  • Ostrovskaya R, Ozerova I, Gudascheva T, Kapitsa I, Ivanova E, Voronina T, Seredenin S. 2014a. Comparative activity of proline-containing dipeptide noopept and inhibitor of dipeptidyl peptidase-4 sitagliptin in a rat model of developing diabetes. Bull Exp Biol Med. 156:342–346. doi:10.1007/s10517-014-2345-z
  • Ostrovskaya R, Vakhitova YV, Kuzmina US, Salimgareeva MK, Zainullina LF, Gudasheva TA, Vakhitov VA, Seredenin SB. 2014b. Neuroprotective effect of novel cognitive enhancer noopept on AD-related cellular model involves the attenuation of apoptosis and tau hyperphosphorylation. J Biomed Sci. 21:1–9. doi:10.1186/s12929-014-0074-2
  • Ostrovskaya R, Zolotov N, Ozerova I, Ivanova E, Kapitsa I, Taraban K, Michunskaya A, Voronina T, Gudasheva T, Seredenin S. 2014c. Noopept normalizes parameters of the incretin system in rats with experimental diabetes. Bull Exp Biol Med. 157:344–349. doi:10.1007/s10517-014-2562-5
  • Pulgaron ER, Delamater AM. 2014. Obesity and type 2 diabetes in children: epidemiology and treatment. Curr Diabetes Rep. 14:508–520. doi:10.1007/s11892-014-0508-y
  • Roglic G. 2016. WHO Global report on diabetes: a summary. Int J Noncommun Dis. 1:3–8. doi:10.4103/2468-8827.184853
  • Sifuentes-Franco S, Pacheco-Moisés FP, Rodríguez-Carrizalez AD, Miranda-Díaz AG. 2017. The role of oxidative stress, mitochondrial function, and autophagy in diabetic polyneuropathy. J Diabetes Res. 2017:1–15. Article 1673081. doi:10.1155/2017/1673081
  • Silvares RR, Pereira ENGS, Flores EEI, Estato V, Reis PA, Silva I, Machado MP, Neto HCdCF, Tibiriça E, Daliry A. 2016. Combined therapy with metformin and insulin attenuates systemic and hepatic alterations in a model of high‐fat diet‐streptozotocin‐induced diabetes. Int J Exp Pathol. 97:266–277. doi:10.1111/iep.12184
  • Sumi A, Iwase M, Nakamura U, Fujii H, Ohkuma T, Ide H, Jodai‐kitamura T, Komorita Y, Yoshinari M, Kitazono T. 2018. Impact of age at menarche on obesity and glycemic control in Japanese patients with type 2 diabetes: fukuoka Diabetes Registry. J Diabetes Invest. 9:1216–1223. doi:10.1111/jdi.12839
  • Sun J, Devish K, Langer WJ, Carmines PK, Lane PH. 2007. Testosterone treatment promotes tubular damage in experimental diabetes in prepubertal rats. Am J Physiol Ren Physiol. 292:F1681–1690. doi:10.1152/ajprenal.00482.2006
  • Ulas M, Orhan C, Tuzcu M, Ozercan IH, Sahin N, Gencoglu H, Komorowski JR, Sahin K. 2015. Anti-diabetic potential of chromium histidinate in diabetic retinopathy rats. BMC Compl Alt Med. 15:1–8. doi:10.1186/s12906-015-0537-3
  • Vardi N, Parlakpinar H, Ates B, Cetin A, Otlu A. 2013. The protective effects of Prunus armeniaca L (apricot) against methotrexate-induced oxidative damage and apoptosis in rat kidney. J Physiol Biochem. 69:371–381. doi:10.1007/s13105-012-0219-2
  • Vardi N, Parlakpinar H, Ozturk F, Ates B, Gul M, Cetin A, Erdogan A, Otlu A. 2008. Potent protective effect of apricot and β-carotene on methotrexate-induced intestinal oxidative damage in rats. Food Chem Toxicol. 46:3015–3022. doi:10.1016/j.fct.2008.05.039
  • Wajchenberg BL. 2007. β-cell failure in diabetes and preservation by clinical treatment. Endocr Rev. 28:187–218. doi:10.1210/10.1210/er.2006-0038
  • Yin J, Huang J, Chen C, Gao N, Wang F, Fu-Shin XY. 2011. Corneal complications in streptozocin-induced type I diabetic rats. Invest Ophthal Vis Sci. 52:6589–6596. doi:10.1167/iovs.11-7709

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.