1,104
Views
31
CrossRef citations to date
0
Altmetric
Original Articles

A Bayesian Case Study in Oncology Phase I Combination Dose-Finding Using Logistic Regression with Covariates

, , &
Pages 469-484 | Published online: 21 Apr 2009

REFERENCES

  • Babb , J. , Rogatko , A. , Zacks , S. ( 1998 ). Cancer Phase I clinical trials: Efficient dose escalation with overdose control . Statist. Med. 17 ( 10 ): 1103 – 1120 .
  • Eisenhauer , E. A. , Twelves , C. , Buyse , M. ( 2006 ). Phase I Cancer Clinical Trials . London, UK .: Oxford University Press .
  • Joffe , S. , Miller , F. G. ( 2006 ). Rethinking risk-benefit assessment for Phase I cancer trials . J. Clin. Oncol. 24 : 2987 – 2990 .
  • Neuenschwander , B. , Branson , M. , Gsponer , G. (2008). Critical aspects of the Bayesian approach to Phase I cancer trials. Statist. Med. 27(13):2420–2439.
  • Simon , R. , Freidlin , B. , Rubinstein , L. , Arbuck , S. , Collins , J. , Cristian , M. ( 1997 ). Accelerated titration designs for Phase I clinical trials in oncology . J. Natl. Cancer Inst. 89 : 1138 – 1147 .
  • Spiegelhalter , D. J. , Abrams , K. R. , Myles , J. P. ( 2004 ). Bayesian Approaches to Clinical Trials and Healthcare Evaluation . Chichester, UK : John Wiley and Sons .
  • Storer , B. ( 1989 ). Design and analysis of Phase I clinical trials . Biometrics 45 : 925 – 937 .
  • Thall , P. F. , Millikan , R. E. , Mueller , P. , Lee , S. J. ( 2003 ). Dose-finding with two agents in Phase I oncology trials . Biometrics 59 : 487 – 496 .
  • The Committee for Medicinal Products for Human Use (CHMP) . ( 2006 ). Guideline on clinical trials in small populations . CHMP/EWP/83561/2005 .
  • Therasse , P. , Arbuch , S. G. , Eisenhower , E. A. , Wanders , J. , Kaplan , R. S. , Rubinstein , L. , Verweij , J. , Van Glabbeke , M. , van Oosterom , A. T. , Christian , M. C. , Gwyther , S. G. ( 2000 ). New guidelines to evaluate the response to treatment in solid tumors . J. Natl. Cancer Inst. 92 : 205 – 216 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.