134
Views
7
CrossRef citations to date
0
Altmetric
Original Articles

Optimal Two-Stage Randomized Multinomial Designs for Phase II Oncology Trials

, &
Pages 485-493 | Published online: 21 Apr 2009

REFERENCES

  • Fleming , T. R. ( 1982 ). One sample multiple testing procedure for phase II clinical trials . Biometrics 38 : 143 – 151 .
  • et al. . ( 2002 ). Correspondence—multinomial Phase II trial designs . J. Clin. Oncol. 20 : 599 – 599 .
  • Gehan , E. A. ( 1961 ). The determination of the number of patients required in a follow-up trial of a new chemotherapeutic agent . J. Chronic Disease 13 : 346 – 353 .
  • Goffin , J. , Tu , D. ( 2007 ). Phase II stopping rules employing response rates and early progression . American Society of Clinical Oncology Annual Meeting . Poster .
  • Jennison , C. , Turnbull , B. ( 1993 ). Group Sequential Methods with Applications to Clinical Trials . Chapman & Hall .
  • Simon , R. ( 1989 ). Optimal two-stage designs for Phase II clinical trials . Contr. Clin. Trials 10 : 1 – 10 .
  • Simon , R. , Wittes , R. E. , Ellenberg , S. S. ( 1985 ). Randomized Phase II clinical trials . Cancer Treatment Reports 69 : 1375 – 1381 .
  • Simon , R. , Thall , P. F. , Ellenberg , S. S. ( 1994 ). New designs for the selection of treatments to be tested in randomized clinical trials . Stat. Med. 13 : 417 – 429 .
  • Stallard , N. , Thall , P. F. , Whitehead , J. ( 1999 ). Decision theoretic designs for Phase II clinical trials with multiple outcomes . Biometrics 55 : 971 – 977 .
  • Thall , P. F. , Sung , H. ( 1998 ). Some extensions and applications of a Bayesian strategy for monitoring multiple outcomes in clinical trials . Stat. Med. 17 : 1563 – 1580 .
  • Thall , P. F. , Cheng , S. ( 1999 ). Treatment comparisons based on two-dimensional safety and efficacy alternatives in oncology trials . Biometrics 55 : 746 – 753 .
  • Thall , P. F. , Simon , R. , Ellenberg , S. S. ( 1989 ). A two-stage design for choosing among several experimental treatments and a control in clinical trials . Biometrics 45 : 537 – 547 .
  • Thall , P. F. , Simon , R. M. , Estey , E. H. ( 1995 ). Bayesian sequential monitoring designs for single-arm clinical trials with multiple outcomes . Stat. Med. 14 : 357 – 379 .
  • Zee , B. , Melnychuk , D. , Dancey , J. , Eisenhaver , E. ( 1999 ). Multinomial Phase II cancer trials incorporating response and early progression . J. Biopharm. Stat. 9 ( 2 ): 351 – 363 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.