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Original Articles

An Efficient Algorithm to Determine the Optimal Two-Stage Randomized Multinomial Designs in Oncology Clinical Trials

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Pages 56-65 | Received 14 Jul 2009, Accepted 08 Dec 2009, Published online: 29 Dec 2010

REFERENCES

  • Dent , S. , Zee , B. , Dancey , J. , Hanauske , A. , Wanders , J. , Eisenhauer , E. ( 2001 ). Application of a new multinomial phase II stopping rule using response and early progression . Journal of Clinical Oncology 19 : 785 – 791 .
  • Rubinstein , L. V. , Korn , E. L. , Freidlin , B. , Hunsberger , S. , Ivy , S. P. , Smith , M. A. ( 2005 ). Design issues of randomized phase II trials and a proposal for phase II screening trials . Journal of Clinical Oncology 23 : 7199 – 7206 .
  • Sun , L. Z. , Chen , C. , Patel , K. ( 2009 ). Optimal two-stage randomized multinomial designs for phase II oncology trials . Journal of Biopharmaceutical Statistics 19 : 485 – 493 .
  • This paper is a follow-up communication to Sun et al. (2009).

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