137
Views
0
CrossRef citations to date
0
Altmetric
Original Articles

A Bayesian Measurement Error Approach to QT Interval Correction and Prolongation

&
Pages 523-542 | Received 12 Jun 2009, Accepted 13 Oct 2009, Published online: 21 Apr 2010

REFERENCES

  • Bazett , H. C. ( 1920 ). An analysis of time relations of the electrocardiograms . Heart 7 : 353 – 367 .
  • Benjamini , Y. , Hochberg , Y. (1995). Controlling the false discovery rate: a practical and powerful approach to multiple testing. J. R. Stat. Society Ser. B 57:289–300.
  • Benjamini , Y. , Liu , W. ( 1999 ). A step-down multiple hypothesis testing procedure that controls the false discovery rate under independence . J. Stat. Plan. Inference 82 : 163 – 170 .
  • Berger , R. L. ( 1982 ). Multiparameter hypothesis testing and acceptance sampling . Technometrics 24 : 295 – 300 .
  • Carroll , R. J. , Ruppert , D. , Stefanski , L. A. ( 1995 ). Measurement Error in Nonlinear Models . Boca Raton , FL : Chapman & Hall/CRC .
  • Casella , G. , Berger , R. L. ( 1987 ). Reconciling Bayesian and frequentist evidence in the one-wised testing problem . J. Am. Stat. Assoc. 82 : 106 – 111 .
  • Chan , S. F. , Macaskilla , P. , Irwiga , L. , Walter , S. D. ( 2004 ). Adjustment for baseline measurement error in randomized controlled trials induces bias . Controlled Clin. Trials 25 : 408 – 416 .
  • Desai , M. , Li , L. , Desta , Z. , Malik , M. , Flockhart , D. ( 2002 ). Variability of heart rate correction methods for the QT interval . Br. J. Clin. Pharmacol. 55 : 511 – 517 .
  • Dmitrienko , A. , Smith , B. P. ( 2002 ). Analysis of the QT interval in clinical trials . Drug Information J. 36 : 269 – 279 .
  • Efron , B. , Tibshirani , R. , Storey , J. D. , Tusher , V. ( 2001 ). Empirical Bayes analysis of a microarray experiment . J. Am. Stat. Assoc. 96 : 1151 – 1160 .
  • Food and Drug Administration . ( 2006 ). Critical path opportunities list. Technical Report, U.S. Food and Drug Administration. March. Available at: http://www.fda/gov/oc/initiatives/criticalpath/
  • Fridericia , L. S. ( 1920 ). The duration of systole in the electrocardiogram of normal subjects and of patients with heart disease . Acta Med. Scand. 53 : 469 – 486 .
  • Genz , A. , Bretz , F. , Hothorn , T. ( 2005 ). Multivariate normal and t-distribution mvtnorm. R Foundation for Statistical Computing. R package version 0.7-2 .
  • Hochberg , Y. , Tamhane , A. C. ( 1987 ). Multiple Comparison Procedures . New York : John Wiley & Sons .
  • Hsu , J. C. ( 1996 ). Multiple Comparisons: Theory and Methods . Washington , DC : Chapman & Hall/CRC .
  • International Conference on Harmonization . ( 2002 ). The clinical evaluation of QT/QTc interval prolongation and proarrhythmic potential for non-antiarrhythmic drugs. October. European Medicines Agency, Canary Wharf, London, UK .
  • Jeffreys , H. ( 1961 ). Theory of Probability . New York , NY, USA : Oxford University Press .
  • Li , L. , Desai , M. , Desta , Z. , Flockhart , D. ( 2004 ). QT Interval: A complex answer to a “simple problem.” Stat. Med. 23 : 2625 – 2643 .
  • Malik , M. ( 2001 ). Problems of heart rate correction in assessment of drug-induced QT interval prolongation . J. Cardiovasc. Electrophysiol. 12 : 411 – 420 .
  • McNames , J. , Thong , T. , Goldstein , B. ( 2003 ). Reliability and accuracy of heart rate variability matrics versus ECG segment duration . IEEE EMBC 1 : 212 – 215 . DOI: 10.1109/IEMBS.2003.1279574
  • Moss , A. J. ( 1999 ). The QT interval and torsade de pointes . Drug Safety 21 ( suppl. 1 ): 5 – 10 .
  • Newton , M. A. , Noueiry , A. , Sarkar , D. , Ahlquist , P. ( 2004 ). Detecting differential gene expression with a semiparametric hierarchical mixture method . Biostatistics 5 : 155 – 176 .
  • Patterson , S. D. , Jones , B. , Zariffa , N. ( 2005 ). Modeling and interpreting QTc prolongation in clinical pharmacology studies . Drug Information J. 39 : 437 – 445 .
  • PhRMA QT Statistics Expert Working Team . ( 2005 ). Investigating drug-induced QT and QTc prolongation in the clinic: A review of statistical design and analysis consideration: Report from the pharmaceutical research and manufacturers of America QT statistics expert team . Drug Information J. 39 : 243 – 266 .
  • Piccirillo , G. , Cacciafesta , M. , Lionetti , M. , Nocco , M. , Giuseppe , V. D. , Moisè , A. , Naso , C. , Marigliano , V. (2001). Influence of age, the autonomic nervous system and anxiety on QT-interval variability. Clin. Sci. 101:429–438.
  • Pueyo , E. , Smetana , P. , Caminal , P. , de Luna , A. B. , Malik , M. , Laguna , P. ( 2004 ). Characterization of QT interval adaptation to RR interval changes and its use as a risk-stratifier of arrhythmic mortality in amiodarone-treated survivors of acute myocardial infarction . IEEE Trans. Biomed. Eng. 51 : 1511 – 1520 .
  • Richards , A. F. , Norman , J. ( 1981 ). Relation between QT interval and heart rate: new design of physiologically adaptive cardiac pacemaker . Br. Heart J. 45 : 56 – 61 .
  • Roden , D. M. ( 2004 ). Drug-induced prolongation of the QT interval . N. Engl. J. Med. 350 : 1013 – 1022 .
  • Sagie , A. , Larson , M. G. , Goldberg , R. J. , Bengtson , J. R. , Levy , D. ( 1992 ). An improved method for adjusting the QT interval for heart rate—the Framingham study . Am. J. Cardiol. 70 : 797 – 801 .
  • Shaffer , J. P. ( 1999 ). A semi-Bayesian study of Duncan's Bayesian multiple comparison procedures . J. Stat. Plann. Inference 82 : 197 – 213 .
  • Storey , J. D. ( 2002 ). A direct approach to false discovery rates . J. R. Stat. Society Ser. B 64 : 479 – 498 .
  • Sugar , E. , Wang , C.-Y. , Prentice , R. ( 2007 ). Logistic regression with exposure biomarkers and flexible measurement error . Biometrics 63 : 143 – 151 .
  • Wei , G. C. G. , Chen , J. Y. H. ( 2005 ). Model-based correction to the QT interval for heart rate for assessing mean QT interval change due to drug effect . Drug Information J. 39 : 139 – 148 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.