REFERENCES
- Boos , D. D. , Hoffman , D. , Kringle , R. , Zhang , J. ( 2007 ). New confidence bounds for QT studies . Stat. Med. 26 : 3801 – 3817 .
- Cheng , B. , Chow , S.-C. , Burt , D. , Cosmatos , D. ( 2008 ). Statistical assessment of QT/QTc prolongation based on maximum of correlated normal random variables . J. Biopharm. Stat. 18 ( 3 ): 494 – 510 .
- Eaton , M. L. , Muirhead , R. J. , Mancuso , J. Y. , Kolluri , S. ( 2006 ). A confidence interval for the maximal mean QT interval change due drug effect . Drug Information J. 40 : 267 – 271 .
- Efron , B. ( 1997 ). The length heuristic for simultaneous hypothesis tests . Biometrika 84 ( 1 ): 143 – 157 .
- Hochberg , Y. ( 1988 ). A sharper Bonferroni procedure for multiple tests of significance . Biometrika 75 : 800 – 802 .
- Holm , S. ( 1979 ). A simple sequentially rejective multiple test procedure . Scand. J. Stat. 6 : 65 – 70 .
- Hommel , G. ( 1988 ). A stagewise rejective multiple test procedure based on a modified Bonferroni test . Biometrika 75 : 383 – 386 .
- International Conference on Harmonisation . ( 2005 ). ICH (E14) Guidance. The Clinical Evaluation of QT/QTc Interval Prolongation and Proarrhythmic Potential for Non-Antiarrhythmic Drugs . Geneva , Switzerland : International Conference on Harmonisation, May .
- Knowles , M. , Siegmund , D. ( 1988 ). On Hotelling's geometric approach to testing for a nonlinear parameter in regression . Int. Statist. Rev. 57 : 205 – 220 .
- Simes , R. J. ( 1986 ). An improved Bonferroni procedure for multiple tests of significance . Biometrika 73 : 751 – 754 .
- Tsong , Y. , Zhong , J. , Chen , W. J. ( 2008 ). Validation testing in thorough QT/QTc clinical trials . J. Biopharm. Stat. 18 ( 3 ): 529 – 541 .
- Westfall , P. H. , Young , S. S. ( 1993 ). Resampling-Based Multiple Testing: Examples and Methods for p-Value Adjustment . New York : Wiley .
- Westfall , P. H. , Tobias , R. D. , Rom , D. , Wolfinger , R. D. , Hochberg , Y. ( 1999 ). Multiple Comparisons and Multiple Tests Using the SAS System . Cary , NC : SAS Institute, Inc .
- Yan , K. L. , Zhang , J. , Ng , M. J. , Dang , Q. ( 2010 ). Statistical summary of moxifloxacin-induced QTc effect . J. Biopharm. Stat. 20 ( 3 ): 497 – 507 .
- Zhang , J. ( 2008 ). Testing for positive control activity in a thorough QTc study . J. Biopharm. Stat. 18 ( 3 ): 517 – 528 .