REFERENCES
- Uhl GR, Liu QR, Naiman D. Substance abuse vulnerability loci: converging genome scanning data. Trends Genet. 2002;18:420–425. [INFOTRIEVE], [CSA]
- Crabbe JC, Jarvik LF, Liston EH, Jenden DJ. Behavioral responses to amphetamines in identical twins. Acta Genet Med Gemellol (Roma). 1983;32:139–149. [CSA]
- Nurnberger JI Jr, Gershon ES, Simmons S, , et al. Behavioral, biochemical and neuroendocrine responses to amphetamine in normal twins and “well-state” bipolar patients. Psychoneuroendocrinology. 1982;7:163–176. [INFOTRIEVE], [CSA]
- De Wit H, Uhlenhuth EH, Johanson CE. Individual differences in the reinforcing and subjective effects of amphetamine and diazepam. Drug Alcohol Depend. 1986;16:341–360. [INFOTRIEVE], [CSA]
- Gabbay FH. Variations in affect following amphetamine and placebo: markers of stimulant drug preference. Exp Clin Psychopharmacol. 2003;11:91–101. [INFOTRIEVE], [CSA]
- Brauer LH, de Wit H. Subjective responses to d-amphetamine alone and after pimozide pretreatment in normal, healthy volunteers. Biol Psychiatry. 1996;39:26–32. [INFOTRIEVE], [CSA]
- Gainetdinov RR, Wetsel WC, Jones SR, Levin ED, Jaber M, Caron MG. Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity. Science. 1999;283:397–401. [INFOTRIEVE], [CSA]
- Lucki I. The spectrum of behaviors influenced by serotonin. Biol Psychiatry. 1998;44:151–162. [INFOTRIEVE], [CSA]
- Hyman SE. Addiction to cocaine and amphetamine. Neuron. 1996;16:901–904. [INFOTRIEVE], [CSA]
- Brauer LH, De Wit H. High dose pimozide does not block amphetamine-induced euphoria in normal volunteers. Pharmacol Biochem Behav. 1997;56:265–272. [INFOTRIEVE], [CSA]
- Rothman RB, Baumann MH, Dersch CM, , et al. Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin. Synapse. 2001;39:32–41. [INFOTRIEVE], [CSA]
- Budygin EA, Brodie MS, Sotnikova TD, , et al. Dissociation of rewarding and dopamine transporter-mediated properties of amphetamine. Proc Natl Acad Sci USA. 2004;101:7781–7786. [INFOTRIEVE], [CSA]
- Lott DC, Kim SJ, Cook EHJ, De Wit H. Dopamine transporter gene associated with diminished subjective response to amphetamine. Neuropsychopharmacology. 2005;30:602–609. [INFOTRIEVE], [CSA]
- Gelernter J, Cubells JF, Kidd JR, Pakstis AJ, Kidd KK. Population studies of polymorphisms of the serotonin transporter protein gene. Am J Med Genet. 1999;88:61–66. [INFOTRIEVE], [CSA]
- Hranilovic D, Stefulj J, Schwab S, , et al. Serotonin transporter promoter and Intron 2 polymorphisms: relationship between allelic variants and gene expression. Biol Psychiatry. 2004;55:1090–1094. [INFOTRIEVE], [CSA]
- Heils A, Teufel A, Petri S, , et al. Allelic variation of human serotonin transporter gene expression. J Neurochem. 1996;66:2621–2624. [INFOTRIEVE], [CSA]
- Hanna GL, Himle JA, Curtis GC, , et al. Serotonin transporter and seasonal variation in blood serotonin in families with obsessive-compulsive disorder. Neuropsychopharmacology. 1998;18:102–111. [INFOTRIEVE], [CSA]
- Lesch KP, Bengel D, Heils A, , et al. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science. 1996;274:1527–1531. [INFOTRIEVE], [CSA]
- Greenberg BD, Tolliver TJ, Huang SJ, Li Q, Bengel D, Murphy DL. Genetic variation in the serotonin transporter promoter region affects serotonin uptake in human blood platelets. Am J Med Genet. 1999;88:83–87. [INFOTRIEVE], [CSA]
- Nobile M, Begni B, Giorda R, , et al. Effects of serotonin transporter promoter genotype on platelet serotonin transporter functionality in depressed children and adolescents. J Am Acad Child Adolesc Psychiatry. 1999;38:1396–1402. [INFOTRIEVE], [CSA]
- Stoltenberg SF, Twitchell GR, Hanna GL, , et al. Serotonin transporter promoter polymorphism, peripheral indexes of serotonin function, and personality measures in families with alcoholism. Am J Med Genet. 2002;114:230–234. [INFOTRIEVE], [CSA]
- Mortensen OV, Thomassen M, Larsen MB, Whittemore SR, Wiborg O. Functional analysis of a novel human serotonin transporter gene promoter in immortalized raphe cells. Brain Res Mol Brain Res. 1999;68:141–148. [INFOTRIEVE], [CSA]
- Little KY, McLaughlin DP, Zhang L, , et al. Cocaine, ethanol, and genotype effects on human midbrain serotonin transporter binding sites and mRNA levels. Am J Psychiatry. 1998;155:207–213. [INFOTRIEVE], [CSA]
- Heinz A, Jones DW, Mazzanti C, , et al. A relationship between serotonin transporter genotype and in vivo protein expression and alcohol neurotoxicity. Biol Psychiatry. 2000;47:643–649. [INFOTRIEVE], [CSA]
- Sakai K, Nakamura M, Ueno S, , et al. The silencer activity of the novel human serotonin transporter linked polymorphic regions. Neurosci Lett. 2002;327:13–16. [INFOTRIEVE], [CSA]
- Naylor L, Dean B, Pereira A, Mackinnon A, Kouzmenko A, Copolov D. No association between the serotonin transporter-linked promoter region polymorphism and either schizophrenia or density of the serotonin transporter in human hippocampus. Mol Med. 1998;4:671–674. [INFOTRIEVE], [CSA]
- Willeit M, Stastny J, Pirker W, , et al. No evidence for in vivo regulation of midbrain serotonin transporter availability by serotonin transporter promoter gene polymorphism. Biol Psychiatry. 2001;50:8–12. [INFOTRIEVE], [CSA]
- Shioe K, Nakamura M, Ueno S, , et al. No association between genotype of the promoter region of serotonin transporter gene and serotonin transporter binding in human brain measured by PET. Synapse. 2003;48:184–188. [INFOTRIEVE], [CSA]
- Hariri AR, Mattay VS, Tessitore A, , et al. Serotonin transporter genetic variation and the response of the human amygdala. Science. 2002;297:400–403. [INFOTRIEVE], [CSA]
- Konishi T, Luo HR, Calvillo M, Mayo MS, Lin KM, Wan YJ. ADH1B*1, ADH1C*2, DRD2 (-141C Ins), and 5-HTTLPR are associated with alcoholism in Mexican American men living in Los Angeles. Alcohol Clin Exp Res. 2004;28:1145–1152. [INFOTRIEVE], [CSA]
- Sen S, Burmeister M, Ghosh D. Meta-analysis of the association between a serotonin transporter promoter polymorphism (5-HTTLPR) and anxiety-related personality traits. Am J Med Genet. 2004;127B:85–89. [CSA]
- MacKenzie A, Quinn J. A serotonin transporter gene Intron 2 polymorphic region, correlated with affective disorders, has allele-dependent differential enhancer-like properties in the mouse embryo. Proc Natl Acad Sci USA. 1999;96:15251–15255. [INFOTRIEVE], [CSA]
- Lovejoy EA, Scott AC, Fiskerstrand CE, Bubb VJ, Quinn JP. The serotonin transporter intronic VNTR enhancer correlated with a predisposition to affective disorders has distinct regulatory elements within the domain based on the primary DNA sequence of the repeat unit. Eur J Neurosci. 2003;17:417–420. [INFOTRIEVE], [CSA]
- Fiskerstrand CE, Lovejoy EA, Quinn JP. An intronic polymorphic domain often associated with susceptibility to affective disorders has allele-dependent differential enhancer activity in embryonic stem cells. FEBS Lett. 1999;458:171–174. [INFOTRIEVE], [CSA]
- Jonsson EG, Nothen MM, Gustavsson JP, , et al. Polymorphisms in the dopamine, serotonin, and norepinephrine transporter genes and their relationships to monoamine metabolite concentrations in CSF of healthy volunteers. Psychiatry Res. 1998;79:1–9. [INFOTRIEVE], [CSA]
- Kaiser R, Muller-Oerlinghausen B, Filler D, , et al. Correlation between serotonin uptake in human blood platelets with the 44-bp polymorphism and the 17-bp variable number of tandem repeat of the serotonin transporter. Am J Med Genet. 2002;114:323–328. [INFOTRIEVE], [CSA]
- Fan JB, Sklar P. Meta-analysis shows association between serotonin tranporter gene ST in 2 VNTR Polymorphism and schizophrenia. Mol Psychiatry. 2005;10:928–38, 891. [INFOTRIEVE], [CSA]
- Veenstra-Vander Weele J, Anderson GM, Cook EH, Jr. Pharmacogenetics and the serotonin system: initial studies and future directions. Eur J Pharmacol. 2000;410:165–181. [CSA]
- Kim SJ, Cox N, Courchesne R, , et al. Transmission disequilibrium mapping at the serotonin transporter gene (SLC6A4) region in autistic disorder. Mol Psychiatry. 2002;7:278–288. [INFOTRIEVE], [CSA]
- Mattay VS, Goldberg TE, Fera F, , et al. Catechol O-methyltransferase val158-met genotype and individual variation in the brain response to amphetamine. Proc Natl Acad Sci USA. 2003;100:6186–6191. [INFOTRIEVE], [CSA]
- Alsene K, Deckert J, Sand P, de Wit H. Association between A2a receptor gene polymorphisms and caffeine-induced anxiety. Neuropsychopharmacology. 2003;28:1694–1702. [INFOTRIEVE], [CSA]
- Derogatis L. SCL-90-R Manual II. Towson, MD: Clinical Psychometric Research; 1983.
- Selzer ML. The Michigan alcoholism screening test: the quest for a new diagnostic instrument. Am J Psychiatry. 1971;127:1653–1658. [INFOTRIEVE], [CSA]
- American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. Fourth edition. Washington, DC: American Psychiatric Association; 1994.
- White TL, Justice AJ, de Wit H. Differential subjective effects of d-amphetamine by gender, hormone levels and menstrual cycle phase. Pharmacol Biochem Behav. 2002;73:729–741. [INFOTRIEVE], [CSA]
- Johanson CE, Uhlenhuth EH. Drug preference and mood in humans: diazepam. Psychopharmacology (Berl). 1980;71:269–273. [CSA]
- McNair D,, Lorr M,, Droppleman DL.. Profile of Mood States. San Diego: Educational and Industrial Testing Service; 1971.
- Martin WR, Sloan JW, Sapira JD, Jasinski DR. Physiologic, subjective, and behavioral effects of amphetamine, methamphetamine, ephedrine, phenmetrazine, and methylphenidate in man. Clin Pharmacol Ther. 1971;12:245–258. [INFOTRIEVE], [CSA]
- Foltin RW, Fischman MW. Assessment of abuse liability of stimulant drugs in humans: a methodological survey. Drug Alcohol Depend. 1991;28:3–48. [INFOTRIEVE], [CSA]
- Pritchard JK, Stephens M, Rosenberg NA, Donnelly P. Association mapping in structured populations. Am J Hum Genet. 2000;67:170–181. [INFOTRIEVE], [CSA]
- Kroeze WK, Kristiansen K, Roth BL. Molecular biology of serotonin receptors—structure and function at the molecular level. Curr Top Med Chem. 2002;2:507–528. [INFOTRIEVE], [CSA]
- Becker KG. The common variants/multiple disease hypothesis of common complex genetic disorders. Med Hypotheses. 2004;62:309–317. [INFOTRIEVE], [CSA]
- White FJ. Drug addiction: cocaine and the serotonin saga. Nature. 1998;393:118–119. [INFOTRIEVE], [CSA]
- Geyer MA. Serotonergic functions in arousal and motor activity. Behav Brain Res. 1996;73:31–35. [INFOTRIEVE], [CSA]
- DiFranza JR, Savageau JA, Fletcher K, , et al. Recollections and repercussions of the first inhaled cigarette. Addict Behav. 2004;29:261–272. [INFOTRIEVE], [CSA]
- Fergusson DM, Horwood LJ, Lynskey MT, Madden PAF. Early reactions to cannabis predict later dependence. Arch Gen Psychiatry. 2003;60:1033–1039. [INFOTRIEVE], [CSA]
- Haertzen CA, Kocher TR, Miyasato K. Reinforcements from the first drug experience can predict later drug habits and/or addiction: results with coffee, cigarettes, alcohol, barbiturates, minor and major tranquilizers, stimulants, marijuana, hallucinogens, heroin, opiates and cocaine. Drug Alcohol Depend. 1983;11:147–165. [INFOTRIEVE], [CSA]
- Schuckit MA, Smith TL. The relationships of a family history of alcohol dependence, a low level of response to alcohol and six domains of life functioning to the development of alcohol use disorders. J Stud Alcohol. 2000;61:827–835. [INFOTRIEVE], [CSA]