Effects of Naltrexone During the Descending Limb of the Blood Alcohol Curve

REFERENCES

• Grobin A C, Matthews D B, Devaud L L, Morrow A L. The role of GABA(A) receptors in the acute and chronic effects of ethanol. Psychopharmacology (Berl) 1998; 139: 2–19
   PubMed Web of Science ®Google Scholar
• Herz A. Endogenous opioid systems and alcohol addiction. Psychopharmacology (Berl) 1997; 129: 99–111
   PubMed Web of Science ®Google Scholar
• Earleywine M. Confirming the factor structure of the anticipated biphasic alcohol effects scale. Alcohol Clin Exp Res 1994; 18: 861–866
   PubMedGoogle Scholar
• Earleywine M. Anticipated biphasic effects of alcohol vary with risk for alcoholism: A preliminary report. Alcohol Clin Exp Res 1994; 18: 711–714
   PubMed Web of Science ®Google Scholar
• Earleywine M, Martin C. Anticipated stimulant and sedative effects of alcohol vary with dosage and limb of the blood alcohol curve. Alcohol Clin Exp Res 1993; 17: 135–139
   PubMed Web of Science ®Google Scholar
• Erblich J, Earleywine M, Erblich B, Bovbjerg D H. Biphasic stimulant and sedative effects of ethanol: Are children of alcoholics really different?. Addict Behav 2003; 28: 1129–1139
   PubMed Web of Science ®Google Scholar
• Martin C S, Earleywine M, Musty R E, Perrine M W, Swift R M. Development and validation of the Biphasic Alcohol Effects Scale. Alcohol Clin Exp Res 1993; 17: 140–146
   PubMed Web of Science ®Google Scholar
• Lewis M J, June H L. Neurobehavioral studies of ethanol reward and activation. Alcohol 1990; 7: 213–219
   PubMedGoogle Scholar
• Wise R A, Bozarth M A. A psychomotor stimulant theory of addiction. Psychol Rev 1987; 94: 469–492
   PubMed Web of Science ®Google Scholar
• Leigh B C. Beliefs about the effects of alcohol on self and others. J Stud Alcohol 1987; 48: 467–475
   PubMed Web of Science ®Google Scholar
• O'Malley S, Maisto S. Factors affecting the perception of intoxication: Dose, tolerance, and setting. Addict Behav 1984; 9: 111–120
   PubMed Web of Science ®Google Scholar
• Balldin J, Berglund M, Borg S, et al. A six-month controlled naltrexone study: Combined effect with cognitive behavioral therapy in outpatient treatment of alcohol dependence. Alcohol Clin Exp Res 2003; 27: 1142–1149
   PubMed Web of Science ®Google Scholar
• Monti P M, Rohsenow D J, Swift R M, et al. Naltrexone and cue exposure with coping and communication skills training for alcoholics: Treatment process and one-year outcomes. Alcohol Clin Exp Res 2001; 25: 1634–1647
   PubMed Web of Science ®Google Scholar
• Rubio G, Manzanares J, Lopez-Munoz F, et al. Naltrexone improves outcome of a controlled drinking program. J Subst Abuse Treat 2002; 23: 361–366
   PubMed Web of Science ®Google Scholar
• Anton R F, Moak D H, Waid L R, Latham P K, Malcolm R J, Dias J K. Naltrexone and cognitive behavioral therapy for the treatment of outpatient alcoholics: Results of a placebo-controlled trial. Am J Psychiatry 1999; 156: 1758–1764
   PubMed Web of Science ®Google Scholar
• Guardia J, Caso C, Arias F, et al. A double-blind, placebo-controlled study of naltrexone in the treatment of alcohol-dependence disorder: Results from a multicenter clinical trial. Alcohol Clin Exp Res 2002; 26: 1381–1387
   PubMed Web of Science ®Google Scholar
• Kiefer F, Jahn H, Tarnaske T, et al. Comparing and combining naltrexone and acamprosate in relapse prevention of alcoholism: A double-blind, placebo-controlled study. Arch Gen Psychiatry 2003; 60: 92–99
   PubMed Web of Science ®Google Scholar
• Heinala P, Alho H, Kiianmaa K, Lonnqvist J, Kouppasalmi K, Sinclair J D. Targeted use of naltrexone without prior detoxification in the treatment of alcohol dependence: A factorial double-blind, placebo-controlled trial. J Clin Psychopharmacol 2001; 21: 287–292
   PubMed Web of Science ®Google Scholar
• Latt N C, Jurd S, Houseman J, Wultzke S E. Naltrexone in alcohol dependence: A randomized controlled trial of effectiveness in a standard clinical setting. Med J Aust 2002; 176: 530–534
   PubMed Web of Science ®Google Scholar
• Volpicelli J R, Alterman A I, Hayashida M, O'Brien C P. Naltrexone in the treatment of alcohol dependence. Arch Gen Psychiatry 1992; 49: 876–880
   PubMed Web of Science ®Google Scholar
• O'Malley S S, Jaffe A J, Change G, Schottenfeld R S, Meyer R E, Rounsaville B. Naltrexone and coping skills therapy for alcohol dependence: A controlled study. Arch Gen Psychiatry 1992; 49: 881–887
   PubMed Web of Science ®Google Scholar
• Chick J, Anton R, Checinski K, et al. A multicentre, randomized, double-blind, placebo-controlled trial of naltrexone in the treatment of alcohol dependence or abuse. Alcohol Alcohol 2000; 35: 587–593
   PubMed Web of Science ®Google Scholar
• Morris P L, Hopwood M, Whelan G, Gardiner J, Drummond E. Naltrexone for alcohol dependence: A randomized controlled trial. Addiction 2001; 96: 1565–1573
   PubMed Web of Science ®Google Scholar
• Anton R F, O'Malley S S, Ciraulo D A, et al. Combined pharmacotherapies and behavioral interventions for alcohol dependence, the COMBINE study: A randomized controlled trial. JAMA 2006; 295: 2003–2017
   PubMed Web of Science ®Google Scholar
• Kranzler H R, Modesto-Lowe V, Van Kirk J. Naltrexone vs. nefazedone for treatment of alcohol dependence: A placebo-controlled trial. Neuropsychopharmacology 2000; 22: 493–503
   PubMed Web of Science ®Google Scholar
• Killeen T K, Brady K T, Gold P B, et al. Effectiveness of naltrexone in a community treatment program. Alcohol Clin Exp Res 2004; 28: 1710–1717
   PubMed Web of Science ®Google Scholar
• Krystal J H, Cramer J A, Krol W F, Kirk G F, Rosenheck R A. Naltrexone in the treatment of alcohol dependence. N Engl J Med 2001; 345: 1734–1739
   PubMed Web of Science ®Google Scholar
• Anton R F, Drobes D J, Voronin K, Durazo-Avizu R, Moak D. Naltrexone effects on alcohol consumption in a clinical laboratory paradigm: Temporal effects of drinking. Psychopharmacology (Berl) 2004; 173: 32–40
   PubMed Web of Science ®Google Scholar
• Drobes D J, Anton R F, Thomas S E, Vornin K. Effects of naltrexone and namefene on subjective response to alcohol among non-treatment seeking alcoholics and social drinkers. Alcohol Clin Exp Res 2004; 28: 1362–1370
   PubMed Web of Science ®Google Scholar
• King A C, Volpicelli J R, Frazer A, O'Brien C P. Effects of naltrexone on subjective alcohol response in subjects at high and low risk for future alcohol dependence. Psychopharmacology (Berl) 1997; 129: 15–22
   PubMed Web of Science ®Google Scholar
• McCaul M E, Wand G S, Stauffer R, Lee S M, Rohde C A. Naltrexone dampens ethanol-induced cardiovascular and hypothalamic-pituitary-adrenal axis activation. Neuropsychopharmacology 2001; 25: 537–547
   PubMed Web of Science ®Google Scholar
• Ray L A, Hutchison K E. A double-blind placebo-controlled study of the effects of naltrexone on alcohol sensitivity and genetic moderators of medication response. Arch Gen Psychiatry 2007; 64: 1069–1077
   PubMed Web of Science ®Google Scholar
• Swift R M, Whelihan W, Kusnetsov O, Buongiorno G, Hsuing H. Naltrexone-induced alterations in human ethanol intoxication. Am J Psychiatry 1994; 151: 1463–1467
   PubMed Web of Science ®Google Scholar
• Volpicelli J R, Watson N T, King A C, Sherman C E, O'Brien C P. Effects of naltrexone on alcohol “high” in alcoholics. Am J Psychiatry 1995; 152: 613–615
   PubMed Web of Science ®Google Scholar
• Davidson D, Palfai T, Bird C, Swift R. Effects of naltrexone on alcohol self-administration in heavy drinkers. Alcohol Clin Exp Res 1999; 23: 195–203
   PubMed Web of Science ®Google Scholar
• O'Malley S S, Krishnan-Sarin S, Farren C, Sinha R, Kreek M J. Naltrexone decreases craving and alcohol self-administration in alcohol-dependent subjects and activates the hypothalamo-pituitary-adrenocortical axis. Psychopharmacology (Berl) 2002; 160: 19–29
   PubMed Web of Science ®Google Scholar
• McCaul M E, Wand G S, Eissenberg T, Thode C A, Cheskin L J. Naltrexone alters subjective and psychomotor responses to alcohol in heavy drinking subjects. Neuropsychopharmacology 2000; 22: 480–492
   PubMed Web of Science ®Google Scholar
• de Wit H, Svenson J, York A. Non-specific effect of naltrexone on ethanol consumption in social drinkers. Psychopharmacology (Berl) 1999; 146: 33–41
   Google Scholar
• Doty P, de Wit H. Effects of naltrexone pretreatment on the subjective and performance effects of ethanol in social drinkers. Behav Pharmacol 1995; 6: 386–394
   Google Scholar
• Doty P, Kirk J M, Cramblett M J, de Wit H. Behavioral responses to ethanol in light and moderate social drinkers following naltrexone pre-treatment. Drug Alcohol Depend 1997; 47: 109–116
   Google Scholar
• Peterson J B, Conrod P, Vassileva J, Gianoulakis C, Pihl R O. Differential effects of naltrexone on cardiac, subjective and behavioural reactions to acute ethanol intoxication. Review of Psychiatric Neuroscience 2006; 31: 386–393
   PubMed Web of Science ®Google Scholar
• Brick J. Standardization of alcohol calculations in research. Alcohol Clin Exp Res 2006; 30: 1276–1287
   PubMed Web of Science ®Google Scholar
• Dunn M E, Earleywine M. Activation of alcohol expectations in memory in relation to limb of the blood alcohol curve. Psychol Addict Behav 2002; 15: 18–24
   Google Scholar
• Soderlund H, Parker E S, Schwartz B L, Tulving E. Memory encoding and retrieval on the ascending and descending limbs of the blood alcohol concentration curve. Psychopharmacology (Berl) 2005; 182: 305–317
   PubMed Web of Science ®Google Scholar
• Pihl R O, Paylan S S, Gentes-Hawn A, Hoaken P NS. Alcohol affects executive cognitive functioning differentially on the ascending versus descending limb of the blood alcohol concentration curve. Alcohol Clin Exp Res 2003; 27: 773–779
   PubMed Web of Science ®Google Scholar
• Evans S M, Levin F R. Differential response to alcohol in light and moderate female social drinkers. Behav Pharmacol 2004; 15: 167–181
   PubMedGoogle Scholar
• Monterosso J R, Flannery B A, Pettinati H M, et al. Predicting treatment response to naltrexone: The influence of craving and family history. Am J Addict 2001; 10: 258–268
   PubMed Web of Science ®Google Scholar
• Rubio G, Ponce G, Rodriguez-Jimenez R, Jimenez-Arriero M A, Hoenicka J, Palomo T. Clinical predictors of response to naltrexone in alcoholic patients: Who benefits most from treatment with naltrexone?. Alcohol Alcohol 2005; 40: 227–233
   PubMed Web of Science ®Google Scholar
• Rohsenow D J, Miranda R, Mcgeary J, Monti P M. Family history and antisocial traits moderate naltrexone's effects on heavy drinking in alcoholics. Exp Clin Psychopharmacol 2007; 15: 272–281
   PubMed Web of Science ®Google Scholar
• Allen J P, Litten R Z, Fertig J B, Babor T. A review of research on the Alcohol Use Disorders Identification Test (AUDIT). Alcohol Clin Exp Res 1997; 21: 613–619
   PubMed Web of Science ®Google Scholar
• Li T, Yin S, Crabb D W, O'Connor S, Ramchandani V A. Genetic and environmental influences on alcohol metabolism in humans. Alcohol Clin Exp Res 2001; 25: 136–144
   PubMed Web of Science ®Google Scholar
• O'Connor S, Morzorati S, Christian J, Li T. Clamping breath alcohol concentration reduces experimental variance: Application to the study of acute tolerance to alcohol and alcohol elimination rate. Alcohol Clin Exp Res 1998; 22: 202–210
   Google Scholar
• Ramchandani V A, Bolane J, Li T K, O'Connor S. A physiologically-based pharmacokinetic (PBPK) model for alcohol facilitates rapid BrAC clamping. Alcohol Clin Exp Res 1999; 23: 617–623
   Google Scholar
• Ray L A, Hutchison K E. A polymorphism of the mu-opioid receptor gene and sensitivity to the effects of alcohol in humans. Alcohol Clin Exp Res 2004; 28: 1789–1795
   PubMed Web of Science ®Google Scholar
• Ray L A, Meskew-Stacer S, Hutchison K E. The relationship between prospective self-rating of alcohol sensitivity and craving and experimental results from two alcohol challenge studies. J Stud Alcohol Drugs 2007; 68: 379–384
   PubMedGoogle Scholar
• Ray L A, McGeary J, Marshall E, Hutchison K E. Risk factors for alcohol misuse: Integrating heart rate response to alcohol, alcohol sensitivity, and personality factors. Addict Behav 2006; 31: 1959–1973
   PubMed Web of Science ®Google Scholar
• Del Boca F K, Kranzler H R, Brown J, Korner P F. Assessment of medication compliance in alcoholics through UV light detection of a riboflavin tracer. Alcohol Clin Exp Res 1996; 20: 1412–1417
   PubMedGoogle Scholar
• Bohn M J, Krahn D D, Staehler B A. Development and initial validation of a measure of drinking urges in abstinent alcoholics. Alcohol Clin Exp Res 1995; 19: 600–606
   PubMed Web of Science ®Google Scholar
• MacKillop J. Factor structure of the alcohol urge questionnaire under neutral conditions and during a cue-elicited urge state. Alcohol Clin Exp Res 2006; 30: 1315–1321
   PubMed Web of Science ®Google Scholar
• Schuckit M A. Subjective responses to alcohol in sons of alcoholics and control subjects. Arch Gen Psychiatry 1984; 41: 879–884
   PubMed Web of Science ®Google Scholar
• McNair D M, Lorr M, Droppleman L F. Manual for the Profile of Mood States. Educational & Industrial Testing Service, San Diego 1971
   Google Scholar
• Jacobson A F, Goldstein B J, Dominguez R A, Steinbook R M. Interrater agreement and interclass reliability measure of SAFTEE in psychopharmacologic clinical trials. Psychopharmacol Bull 1986; 22: 382–388
   Google Scholar
• Levine J, Schooler N. SAFTEE: A technique for systematic assessment of side effects in clinical trials. Psychopharmacol Bull 1986; 22: 343–381
   PubMed Web of Science ®Google Scholar
• Kaplan R, Hesslebrock V, O'Conner S, DePalma N. Behavioral and EEG responses to alcohol in nonalcoholic men with a family history of alcoholism. Prog Neuropsychopharmacol Biol Psychiatry 1988; 12: 873–885
   PubMed Web of Science ®Google Scholar
• Conrod P, Peterson J, Pihl R, Mankowski S. Biphasic effects of alcohol on heart rate are influenced by alcoholic family history and rate of alcohol ingestion. Alcohol Clin Exp Res 1997; 21: 140–149
   PubMedGoogle Scholar
• Garbutt J C, Kranzler H R, O'Malley S S, et al. Efficacy and tolerability of long-acting injectable naltrexone for alcohol dependence: A randomized controlled trial. JAMA 2005; 293: 1617–1625
   PubMed Web of Science ®Google Scholar
• Hernandez-Avila C A, Song C, Kuo L, Tennen H, Armeli S, Kranzler H R. Targeted versus daily naltrexone: Secondary analysis of effects on average daily drinking. Alcohol Clin Exp Res 2006; 30: 860–865
   PubMed Web of Science ®Google Scholar
• Pettinati H M, Kampman K M, Lynch K G, et al. Gender differences with high-dose naltrexone in the patients with co-occurring cocaine and alcohol dependence. J Subst Abuse Treat 2008; 34: 378–390
   PubMed Web of Science ®Google Scholar
• Bond C, LaForge K S, Tian M, et al. Single-nucleotide polymorphism in the human μ-opioid receptor gene alters β-endorphin binding and activity: Possible implications for opiate addiction. Neurobiology. 1998; 95: 9608–9613
   Google Scholar
• Herz A. Endogenous opioid systems and alcohol addiction. Psychopharmacology 1997; 129: 99–111
   PubMed Web of Science ®Google Scholar
• Kreek M J. Opioid receptors: Some perspectives from early studies of their role in normal physiology, stress responsivity, and in specific addictive diseases. Neurochem Res 1996; 21: 1469–1488
   PubMed Web of Science ®Google Scholar
• Krystal J H, Petrakis I L, Webb E, et al. Dose-related ethanol-like effects of the NMDA antagonist, ketamine, in recently detoxified alcoholics. Arch Gen Psychiatry. 1998; 55: 354–360
   PubMed Web of Science ®Google Scholar
• Grobin A C, Matthews D B, Devaud L L, Morrow A L. The role of GABA(A) receptors in the acute and chronic effects of ethanol. Psychopharmacology 1998; 139: 2–19
   PubMed Web of Science ®Google Scholar
• Buck K J. Molecular genetic analysis of the role of GABAergic systems in the behavioral and cellular actions of alcohol. Behav Genet 1996; 26: 313–323
   PubMedGoogle Scholar