Advanced search
Publication Cover
Natural Product Letters Volume 8, 1996 - Issue 1
Journal homepage
33
Views
31
CrossRef citations to date
0
Altmetric
Original Articles

Cordifoliosides A and B, two New Phenylpropene Disaccharides from Tinospora cordifolia possessing Immunostimulant Activity

Rakesh Maurya Regional Research Laboratory, Jammu, 180 001, India
,
Versha Wazir Regional Research Laboratory, Jammu, 180 001, India
,
Aruna Kapil Regional Research Laboratory, Jammu, 180 001, India
&
Randhir S. Kapil Regional Research Laboratory, Jammu, 180 001, India
Pages 7-10 | Published online: 04 Oct 2006

References

  • Indian Patent application Nos. . 558, 559/DEL/93 . 01.06.1993 . These products are covered by
  • Chadha , Y. R. 1976 . The Wealth of India , Vol 10 , 251 New Delhi : Publication and Information Directorate, CSIR .
  • Atta-ur-Rahman , Ali , S. S. , Ahmad , S. and Choudhary , M. I. 1992 . Phytochemistry , 31 : 3155 R. K. Bhat and B. K. Sabata, (1989) Phytochemistry, 28, 2419 and references cited therein
  • Cordifolioside A heptaacetate (1a): 1H NMR (300 MHz, CDCl3): δ 2.00–2.10 (21H, s, 7x OCOMe), 3.59 (1H, m, H-5″), 3.75 (1H, t, J=7.8 Hz, H-3″), 3.82 (6H, s, 2x OMe), 4.04 (1H, dd, J=12.2, 1.2 Hz, H-6b″), 4.04 (1H, d, J=9.8 Hz, H-5b″′), 4.18 (1H, dd, J=12.2, 4.3 Hz, H-6a″), 4.19 (1H, d, J=9.8 Hz, H-5a″′), 4.53 (1H, d, J=13.0 Hz, H-4b″′), 4.64 (1H, d, J=13.0 Hz, H-4a″′), 4.71 (2H, d, J=6.5 Hz, H-1), 4.97 (1H, d, J=7.8 Hz, H-1″), 5.07 (1H, br s, H-1″′), 5.19 (1H, br s, H-2″′), 5.26 (2H, m, H-2″, 4″), 6.21 (1H, dt, J=16.5, 6.5 Hz, H-2), 6.56 (1H, d, J=16.5 Hz, H-3), 6.59 (2H, s, H-2′, 6′); 13C NMR (75 MHz, CDCl3, carbon assignment in parenthesis): δ 20.50 (7x OCOMe), 56.41 (2x OMe), 62.54 (6″), 62.84 (5″′), 64.90(1), 69.08 (4″), 72.01(2″), 72.74 (3″), 72.76 (5″), 76.59 (4″′), 81.88 (2″′), 83.53 (3″′), 101.19 (1″), 104.29 (2′, 6′), 107.53 (1″′), 123.17(2), 132.97 (1′), 133.00 (4′), 134.01(3), 153.00(3′, 5′), 169.72 and 172.00 (7x OCOMe)
  • Mastaka , S. , Eiko , N. and Masaq , K. 1993 . Phytochemistry , 33 : 1215
  • Wagner , H. , Feil , B. , Seligmann , O. , Petricic , J. and Kalogjera , Z. 1986 . Planta Medica , 52 : 102 M. Yonemitsu, N. Fukuda and T. Kimura, (1993) Planta Medica, 59, 552
  • Cordifolioside B heptaacetate (2a): 1H NMR (300 MHz, CDCl3): δ 2.00–2.10 (21H, s, 7× OCOMe), 3.59 (1H, m, H-5″′), 3.78 (1H, d, J=9.8 Hz, H-5b″), 3.83 (6H, s, 2× OMe), 3.87 (1H, d, J=9.8 Hz, H-5a″), 4.17 (1H, dd, J=12.2, 1.2 Hz, H-6b″′), 4.21 (1H, d, J=13.0 Hz, H-4b″), 4.22 (1H, dd, J=12.2, 4.3 Hz, H-6a″′), 4.30 (1H, d, J=13.0 Hz, H-4a″), 4.71 (2H, d, J=6.5 Hz, H-1), 4.87 (1H, s, H-1″), 4.97 (1H, d, J=6.5 Hz, H-1″′), 5.12 (1H, br s, H-2″), 5.27 (3H, m, H-2″′, 3″′, 4″′), 6.21 (1H, dt, J=16.5, 6.5 Hz, H-2), 6.56 (1H, d, J=16.5 Hz, H-3), 6.58 (2H, s, H-2′, 6′); 13C NMR (75 MHz, CDCl3, carbon assignment in parenthesis): δ 20.65 and 20.99 (7× OCOMe), 56.40 (2× OMe), 62.61 (6″′), 64.90(1), 67.02 (5″), 69.08 (4″′), 72.04 (2″′, 3″′), 73.11 (5″′), 74.34 (4″), 78.78 (3″), 81.88 (2″), 101.14 (1″′), 104.20 (2′, 6′), 107.63 (1″), 123.19(2), 132.02 (1′), 133.08 (4′), 134.01(3), 153.19 (3′, 5′), 169.01 and 170.68 (7× OCOMe)
  • Ram , V. J. , Kapil , A. and Guru , P. Y. 1990 . Indian J. Chemistry , 29B : 1129
  • Williams , W. V. , Kyriakos , M. , Sharp , G. C. and Mullen , H. B. 1987 . Cell Immunology , 104 : 296

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.