The Assessment and Significance of the Sleep/Waking Brain in Patients with Chronic Widespread Musculoskeletal Pain and Fatigue Syndromes

REFERENCES

• Moldofsky H, Scarisbrick P, England R, Smythe H. Musculoskeletal symptoms and NonREM sleep disturbance in patients with fibrositis syndrome and healthy subjects. Psychosom Med 1975; 34: 341–351
   Google Scholar
• Wolfe F, Smythe H A, Yunus M B, Bennett R M, Bombardier C, Goldenberg D L, Tugwell P, Campbell S M, Abeles M, Clark P, Fam A G, Farber S J, Fiechtner J J, Franklin C M, Gatter R A, Hamaty D, Lessard J, Lichtbroun A S, Masi A T, McCain G A, Reynolds W J, Romano T J, Russell I J, Sheon R P. The American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia. Arthritis Rheum 1990; 33: 160–172
   PubMed Web of Science ®Google Scholar
• Croft P, Rigby A S, Boswell, Schollum, Silman A. The prevalence of chronic widespread pain in the general population. J Rheumatol 1993; 20: 710–713
   PubMed Web of Science ®Google Scholar
• Croft P, Schollum J, Silman A. Population study of tender point counts and pain as evidence of fibromyalgia. BMJ 1994; 309: 696–699
   PubMed Web of Science ®Google Scholar
• Katz R S, Wolfe F, Michaud K. Fibromyalgia diagnosis: A comparison of clinical, survey, and American College of Rheumatology criteria. Arthritis & Rheum 2006; 54: 169–176
   PubMedGoogle Scholar
• Schochat T, Raspe H. Elements of fibromyalgia in an open population. Rheumatology 2003; 42: 829–835
   PubMed Web of Science ®Google Scholar
• Cohen M L, Quintner J L. Fibromyalgia syndrome: A problem of tautology. Lancet 1993; 342: 906–909
   PubMed Web of Science ®Google Scholar
• Vargas A, Vargas A, Hernandez-Paz R, Sanchez-Huerta J M, Romero-Ramirez R, Amezcua-Guerra L, Kooh M, Nava A, Pineda C, Rodriguez-Leal G, Martinez-Lavin M. Sphygmomanometry-evoked allodynia—a simple bedside test indicative of fibromyalgia: A multicenter developmental study. J Clin Rheumatology 2006; 12(6)272–274
   PubMedGoogle Scholar
• Jason L A, Richman J A, Rademaker A W, Jordan K M, Plioplys A V, Taylor R R, McCready W, Huang C F, Plioplys S. A community-based study of chronic fatigue syndrome. Arch Int Med 1999; 18: 2129–2137
   Google Scholar
• Reyes M, Nisenbaum R, Hoaglin D C, Unger E R, Emmons C, Randall B, Stewart J A, Abbey S, Jones J F, Gantz N, Minden S, Reeves W C. Prevalence and incidence of chronic fatigue syndrome in Wichita, Kansas. Arch Intern Med 2003; 163: 1530–1536
   PubMed Web of Science ®Google Scholar
• Yunus M B, Ahles T A, Aldag J C, Masi A T. The relationship of the clinical features with psychological status in primary fibromyalgia. Arth Rheum 1991; 34: 15–21
   PubMed Web of Science ®Google Scholar
• Ostuni P, Botsios C, Sfriso P, Bertagnin A, Cozzi F, Doria A, Todesco S. Prevalence and clinical features of fibromyalgia in systemic lupus erythematosus, systemic sclerosis and Sjogren's syndrome. Minerva Medica 2002; 93(3)203–209
   PubMedGoogle Scholar
• Tishler M, Barak Y, Paran D, Yaron M. Sleep disturbances, fibromyalgia and primary Sjorgren's syndrome. Clinical and Experimental Rheumatol 1997; 15: 71–74
   PubMed Web of Science ®Google Scholar
• Iaboni A, Ibanez D, Gladman D D, Urowitz M B, Moldofsky H. Fatigue in SLE: Contributions of disordered sleep, sleepiness and depression. J Rheum 2006; 33: 2458–2463
   PubMedGoogle Scholar
• Hoddes E, Zarcone V, Smythe H, Phillips R, Dement W C. Quantification of sleepiness: A new approach. Psychophysiology 1973; 10: 431–436
   PubMed Web of Science ®Google Scholar
• Johns M W. New method for measuring daytime sleepiness: The Epworth sleepiness scale. Sleep 1991; 14: 540–545
   PubMed Web of Science ®Google Scholar
• Abetz L, Arbuckle R, Allen R P, Garcia-Borreguero D, Hening W, Walters A S, Mavraki E, Kirsch J M. The reliability, validity and responsiveness of the International Restless Legs Syndrome Study Group rating scale and subscales in a clinical-trial setting. Sleep Med 2006; 7: 340–349
   PubMed Web of Science ®Google Scholar
• Kump K, Whalen C, Tishler P, Browner I, Ferrette V, Strohl K P, Rosenberg C, Redline S, et al. Assessment of the validity and utility of a sleep-symptom questionnaire. Am J Respir Crit Care Med 1994; 150(3)735–741
   PubMedGoogle Scholar
• Hayes R D, Stewart A L. Sleep measures. Measuring functioning and well-being. The Medical Outcomes Study Approach, A L Stewart, J E Ware, Jr. Duke University Press, Durham, North Carolina 1992; 235–259
   Google Scholar
• Lau D T, Morlock R J, Hill C D. Psychometric evaluation of the medical outcomes study-sleep scale in persons with overactive bladder. Clin Therapeutics 2006; 28: 2119–2132
   PubMedGoogle Scholar
• Buysse D J, Reynolds C F, Monk T H, Berman S R, Kupfer D J. The Pittsburgh Sleep Quality Index: A new instrument for psychiatric practice and research. Psychiatry Res 1989; 28: 193–213
   PubMed Web of Science ®Google Scholar
• Crofford L J, Rowbotham M C, Mease P J, Russell I J, Dworkin R H, Corbin A E, Young J P, Jr, La Moreaux L K, Martin S A, Sharma U. Pregabalin 1009-105 Study Group. Pregabalin for the treatment of fibromyalgia syndrome: Results of a randomized, double-blind, placebo-controlled trial. Arthritis Rheum 2005; 52: 1264–1273
   PubMed Web of Science ®Google Scholar
• Aargun M Y, Tekeolu I, Gune A, Adak B, Kara H, Ercan M. Sleep quality and pain threshold in patients with fibromyalgia. Comprehensive Psychiatry 1999; 40(3)226–228
   PubMedGoogle Scholar
• Osorio C D, Gallinaro A L, Lorenzi-Filho G, Lage L V. Sleep quality in patients with fibromyalgia using the Pittsburgh Sleep Quality Index. J Rheum 2006; 33: 1863–1865
   PubMed Web of Science ®Google Scholar
• Burckhardt C S, Clark S R, Bennett R M. The fibromyalgia impact questionnaire: Development and validation. J Rheum 1991; 18(5)728–733
   PubMed Web of Science ®Google Scholar
• Unger E R, Nisenbaum R, Moldofsky H, Cesta A, Sammut C, Reyes M, Reeves W C. Sleep assessment in a population-based study of chronic fatigue syndrome. BMC Neurol 2004; 4(1)6
   PubMedGoogle Scholar
• Cesta A, Moldofsky H, Sammut C. The sensitivity and specificity of the Sleep Assessment Questionnaire© (SAQ©) as a measure of non-restorative sleep. Sleep 1999; 22(Suppl 1)14
   Google Scholar
• Korszun A, Young E A, Englebert C, Brucksch C B, Greden J F, Crofford L A. Use of actigraphy for monitoring sleep and activity in patients with fibromyalgia and depression. J Psychosom Res 2002; 52: 439–443
   PubMed Web of Science ®Google Scholar
• Hauri P, Hawkins D R. Alpha-delta sleep. Electroencephalogr Clin Neurophysiol 1973; 34: 233–237
   PubMedGoogle Scholar
• Connemann B J, Mann K, Pascual-Marqui R D, Roschke J. Limbic activity in slow wave sleep in a healthy subject with alpha-delta sleep. Psychiatry Research. 2001; 107: 165–71
   PubMedGoogle Scholar
• MacLean A W, Lue F A, Moldofsky H. The reliability of visual scoring of alpha EEG sleep. Sleep 1995; 18: 565–569
   PubMedGoogle Scholar
• Branco J, Atalaia A, Paiva T. Sleep cycles and alpha-delta sleep in fibromyalgia syndrome. J Rheum 1994; 21: 1113–1117
   PubMed Web of Science ®Google Scholar
• Drewes A M, Gade J, Nielsen K D, Bjerregård K, Taagholt S J, Svendsen L. Clustering of sleep encephalographic patterns in patients with the fibromyalgia syndrome. Br J Rheumatol 1995; 34: 1151–1156
   PubMedGoogle Scholar
• Older S A, Battafarano D F, Danning C L, Ward J A, Grady E P, Derman S, Russell I J. The effects of delta wave sleep interruption on pain thresholds and fibromyalgia-like symptoms in healthy subjects; correlations with insulin-like growth factor I. J Rheum 1998; 25: 1180–1186
   PubMed Web of Science ®Google Scholar
• Lentz M J, Landis C A, Rothermel J, Shaver J L. Effects of selective slow wave sleep disruption on musculoskeletal pain and fatigue in middle aged women. J Rheum 1999; 26: 1586–1592
   PubMed Web of Science ®Google Scholar
• Roizenblatt S, Moldofsky H, Benedito A A, Tufik S. Alpha sleep characteristics in fibromyalgia. Arthritis Rheum 2001; 44: 222–230
   PubMed Web of Science ®Google Scholar
• Roizenblatt S, Tufik S, Goldenberg J, Pinto L R, Hilario M O, Feldman D. Juvenile fibromyalgia. Clinical and polysomnographic aspects. J Rheumatol 1997; 24: 579–585
   PubMed Web of Science ®Google Scholar
• MacFarlane J G, Shahal B, Moldofsky H. Periodic K-alpha sleep EEG activity and periodic leg movements during sleep: Comparisons of clinical features and sleep parameters. Sleep 1996; 19: 200–204
   PubMed Web of Science ®Google Scholar
• Rizzi M, Sarzi-Puttini P, Atzeni F, Capsoni F, Andreoli A, Pecis M, Colombo S, Carrabba M, Sergi M. Cyclic alternating pattern: A new marker of sleep alteration in patients with fibromyalgia?. J Rheum 2004; 31: 1193–1199
   PubMed Web of Science ®Google Scholar
• Hamm C, Derman S, Russell J. Sleep parameters in fibrositis/fibromyalgia syndrome (FS). Arthritis Rheum 1989; 32(Suppl 4)S70
   Google Scholar
• Chen L, Baqir M, Schumacher H R, Kuna S T. Increased incidence of sleep apnea in fibromyalgia patients. Arthritis Rheum 2004; 50: S494
   Google Scholar
• May K P, West S G, Baker M R, Everett D W. Sleep apnea in male patients with fibromyalgia syndrome. Am J Med 1993; 94: 505–508
   PubMed Web of Science ®Google Scholar
• Alvarez Lario B, Alonso Valdivielso J L, Alegre Lopez J, Martel Soteres C, Viejo Banuelos J L, Maranon Cabello A. Fibromyalgia syndrome: Overnight falls in arterial oxygen saturation. Am J Med 1996; 101: 54–60
   PubMed Web of Science ®Google Scholar
• Sergi M, Rizzi M, Braghiroli A, Sarzi Puttini P, Greco M, Cazzola M, Andreoli A. Periodic breathing during sleep in patients affected by fibromyalgia syndrome. Eur Respir J 1999; 14: 203–208
   PubMed Web of Science ®Google Scholar
• Gold A R, Dipalo F, Gold M S, Broderick J. Inspiratory airflow dynamics during sleep in women with fibromyalgia. Sleep 2004; 27: 459–466
   PubMed Web of Science ®Google Scholar
• Shah M A, Feinberg S, Krishnan E. Sleep-disordered breathing among women with fibromyalgia syndrome. J Clin Rheumatol 2006; 12: 277–281
   PubMed Web of Science ®Google Scholar
• Ball N, Buchwald D S, Schmidt D, Goldberg J, Ashton S, Armitage R. Monozygotic twins discordant for chronic fatigue syndrome: Objective measures of sleep. J Psychosomatic Research 2004; 56: 207–212
   PubMed Web of Science ®Google Scholar
• Reeves W C, Heim C, Maloney E M, Youngblood L S, Unger E R, Decker M J, Jones J F, Rye D B. Sleep characteristics of persons with chronic fatigue syndrome and non-fatigued controls: results from a population-based study. BMC Neurology 2006; 6: 41
   PubMed Web of Science ®Google Scholar
• Landis C A, Lentz M J, Rothermel J, Buchwald D, Shaver J L. Decreased sleep spindles and spindle activity in midlife women with fibromyalgia and pain. Sleep 2004; 27: 741–750
   PubMed Web of Science ®Google Scholar
• Guilleminault C, Poyares D, Rosa A, Kirisoglu C, Almeida T, Lopes M C. Chronic fatigue, unrefreshing sleep and nocturnal polysomnography. Sleep Medicine 2006; 7: 513–520
   PubMed Web of Science ®Google Scholar
• MacFarlane J G, Doidge M, Twinning I, Krausz S, Mously C, Moldofsky H. Source localization at abnormal cyclical alternating pattern in fibromyalgia patients with nonrestorative sleep. Sleep 2004; 27: A283
   Google Scholar
• Mountz J M, Bradley L A, Alarcon G S. Abnormal functional activity of the central nervous system in fibromyalgia syndrome. Am J Med Sci 1998; 315(6)385–396
   PubMedGoogle Scholar
• Carli G, Montesano A, Rapezzi S, Paluffi G. Differential effects of persistent nociceptive stimulation on sleep stages. Behav Brain Res 1987; 26: 89–98
   PubMed Web of Science ®Google Scholar
• Soja P J, Pang W, Taepavarapruk N, McErlane S A. Spontaneous spike activity of spinalreticular tract during sleep and wakefulness. Sleep 2001; 24: 18–25
   PubMedGoogle Scholar
• Sandrini G, Milanov I, Muri L, Murri L, Alfonsi E, Moglia A, Nappi G. Effects of sleep on spinal nociceptive reflexes in humans. Sleep 2001; 24: 13–17
   PubMedGoogle Scholar
• Hicks R A, Moore J D, Findley P, Hirshfield C, Humphrey V. REM sleep deprivation and pain thresholds in rats. Perceptual & Motor Skills 1978; 47: 848–50, (3 Pt 1)
   PubMed Web of Science ®Google Scholar
• Hicks R A, Coleman D D, Ferrante F, Sahatjian M, Hawkins J. Pain thresholds in rats during recovery from REM sleep deprivation. Percept Mot Skills 1979; 48: 687–690, (3 Pt 1)
   PubMed Web of Science ®Google Scholar
• Hakki Onen S, Alloui A, Jourdan D, Eschalier A, Dubray C. Effects of rapid eye movement (REM) sleep deprivation on pain sensitivity in the rat. Brain Res 2001; 900: 261–267
   PubMed Web of Science ®Google Scholar
• Onen S H, Alloui A, Gross A, Eschallier A, Dubray C. The effects of total sleep deprivation, selective sleep interruption and sleep recovery on pain tolerance thresholds in healthy subjects. J Sleep Research. 2001; 10: 35–42
   PubMed Web of Science ®Google Scholar
• Moldofsky H. Rheumatic pain modulation syndrome: The inter-relationships between sleep, central nervous system serotonin, and pain. Advances in Neurology. Vol 33, M Critchley, A P Freedman, F Sicuteri, S Gorini. Raven Press, New York 1982; 51–57
   Google Scholar
• Russell I J. The promise of substance P inhibitors in fibromyalgia. Rheum Dis Clin North Am 2002; 28(2)329–3242
   PubMed Web of Science ®Google Scholar
• Andersen M L, Nascimento D L, Machado R B, Roizenblatt S, Moldofsky H, Tufik S. Sleep disturbance induced by Substance P in mice. Behav Brain Res 2006; 167: 212–218
   PubMed Web of Science ®Google Scholar
• Drewes A M, Nielson K D, Arendt-Nielson L, Birket-Smith L, Hansen L M. The effect of cutaneous and deep pain on the electroencephalogram during sleep B an experimental study. Sleep 1997; 20: 632–640
   PubMed Web of Science ®Google Scholar
• Lavigne G, Brousseau M, Kato T, Mayer P, Manzini C, Guitard F, Monplaisir J. Experimental pain perception remains equally active over all sleep stages. Pain 2004; 110: 646–655
   PubMed Web of Science ®Google Scholar
• Moldofsky H, Scarisbrick P. Induction of neurasthenic musculoskeletal pain syndrome by selective sleep stage deprivation. Psychosom Med 1976; 38: 35–44
   PubMed Web of Science ®Google Scholar
• Older S A, Battafarano D F, Danning C L, Ward J A, Grady E P, Derman S, Russell I J. The effects of delta wave sleep interruption on pain thresholds and fibromyalgia-like symptoms in healthy subjects; correlations with insulin-like growth factor I. J Rheumatol 1998; 25: 1180–1186
   PubMed Web of Science ®Google Scholar
• Lentz M J, Landis C A, Rothermel J, Shaver J L. Effects of selective slow wave sleep disruption on musculoskeletal pain and fatigue in middle aged women. J Rheumatol 1999; 26: 1586–1592
   PubMed Web of Science ®Google Scholar
• Arima T, Svensson P, Rasmussen C, Nielsen K D, Drewes A M, Arendt-Nielsen L. The relationship between selective sleep deprivation, nocturnal jaw-muscle activity and pain in healthy men. J Oral Rehab 2001; 28: 140–148
   PubMed Web of Science ®Google Scholar
• Kundermann B, Spernal J, Huber M T, Krieg J C, Lautenbacher S. Sleep deprivation affects thermal pain thresholds but not somatosensory thresholds in healthy volunteers. Psychosom Med 2004; 66: 932–937
   PubMed Web of Science ®Google Scholar
• Roehrs T, Hyde M, Blaisdell B, Greenwald M, Roth T. Sleep loss and REM sleep loss are hyperalgesic. Sleep 2006; 29: 145–151
   PubMed Web of Science ®Google Scholar
• Haack M, Mullington J M. Sustained sleep restriction reduces emotional and physical well-being. Pain 2005; 119: 56–64
   PubMed Web of Science ®Google Scholar
• Smith M T, Edwards R R, McCann U D, Haythornthwaite J A. The effects of sleep deprivation on pain inhibition and spontaneous pain in women. Sleep 2007; 30: 494–505
   PubMed Web of Science ®Google Scholar
• Saskin P, Moldofsky H, Lue F A. Sleep and post-traumatic rheumatic pain modulation disorder (Fibrositis Syndrome). Psychosomatic Med 1986; 48(5)319–323
   PubMed Web of Science ®Google Scholar
• Moldofsky H, Saskin P, Lue F A. Sleep and symptoms following a febrile illness in fibrositis syndrome. J Rheumatol 1988; 15: 1701–1704
   PubMedGoogle Scholar
• Scheuler W, Kubicki S, Marquardt J, Scholz G, Weiss K H. The alpha-sleep pattern-quantitative analysis and functional aspects. Sleep 1986, W P Koella, F Obál, H Schulz, P Visser. Gustav Fischer Verlag, New York 1988; 284–286
   Google Scholar
• Frank B, Niesler B, Bondy B, Spath M, Pongratz D E, Ackenheil M, Fischer C, Rappold G. Mutational analysis of serotonin receptor genes: HTR3A and HTR3B in fibromyalgia patients. Clin Rheumatol 2004; 23: 338–344
   PubMedGoogle Scholar
• Gurbaxani B M, Jones J F, Goertzel B N, Maloney E M. Linear data mining the Wichita clinical matrix suggests sleep and allostatic load involvement in chronic fatigue syndrome. Pharmacogenomics 2006; 7: 455–465
   PubMedGoogle Scholar
• Kato K, Sullivan P F, Evengard B, Pedersen N L. Importance of genetic influences on chronic widespread pain. Arthritis Rheum 2006; 54: 1682–1686
   PubMedGoogle Scholar
• Russell I J. The promise of substance P inhibitors in fibromyalgia. Rheum Dis Clin North Am 2002; 28: 329–342
   PubMed Web of Science ®Google Scholar
• Bennett R M. Adult growth hormone deficiency in patients with fibromyalgia. Curr Rheumatol Rep 2002; 4: 306–312
   PubMedGoogle Scholar
• McLean S A, Williams D A, Harris R E. Momentary relationship between cortisol secretion and symptoms in patients with fibromyalgia. Arthritis Rheum 2005; 52: 3660–3669
   PubMed Web of Science ®Google Scholar
• Sarzi-Puttini P, Artzeni F, Diana A, Doria A, Furlan R. Increased neural sympathetic activation in fibromyalgia syndrome. Ann N Y Acad Sci 2006; 1069: 109–117
   PubMed Web of Science ®Google Scholar
• Reynolds W J, Moldofsky H, Saskin P, Lue F A. The effects of cyclobenzaprine on sleep physiology and symptoms in patients with fibromyalgia. J Rheumatol 1991; 18: 452–454
   PubMed Web of Science ®Google Scholar
• Carette S, Oakson G, Guimont C, Steriade M. Sleep electroencephalography and the clinical response to amitriptyline in patients with fibromyalgia. Arthritis Rheum 1995; 38: 1211–1217
   PubMed Web of Science ®Google Scholar
• Moldofsky H, Lue F A. The relationship of alpha and delta EEG frequencies to pain and mood in ‘fibrositis’ patients treated with chlorpromazine and L-tryptophan. Electroencephalogr Clin Neurophysiol 1980; 50: 71–80
   PubMedGoogle Scholar
• Caruso I, Sarzi Puttini P, Cazzola M, Azzolini V. Double-blind study of 5-hydroxytryptophan versus placebo in the treatment of primary fibromyalgia syndrome. Journal of International Medical Research 1990; 18: 201–209
   PubMed Web of Science ®Google Scholar
• Suarez-Roca H, Quintero L, Arcaya J L, Maixner W, Rao S G. Stress-induced muscle and cutaneous hyperalgesia: differential effect of milnacipran. Physio Behav 2006; 88: 82–87
   PubMedGoogle Scholar
• Lemoine P, Faivre T. Subjective and polysomnographic effects of milnacipran on sleep in depressed patients. Human Psychopharmacology 2004; 19: 299–303
   PubMedGoogle Scholar
• Holman A J, Myers R R. A randomized, double blind, placebo controlled trial of pramipexole, a dopamine agonist, in patients with fibromyalgia receiving concomitant medications. Arthritis Rheum 2005; 52: 2495–2505
   PubMed Web of Science ®Google Scholar
• Ryan M, Slevin J T. Restless legs syndrome. Am J Health-System Phar 2006; 63: 1599–1612
   PubMed Web of Science ®Google Scholar
• Scharf M B, Baumann M, Berkowitz D V. The effect of sodium oxybate on clinical symptoms and sleep patterns in patients with fibromyalgia. J Rheum 2003; 30: 1070–1074
   PubMed Web of Science ®Google Scholar