76
Views
7
CrossRef citations to date
0
Altmetric
ARTICLES

Differences in Pressure-Pain Threshold Between Healthy Women and Patients with Fibromyalgia Syndrome, Systemic Lupus Erythematosus, and Rheumatoid Arthritis

, MA, , PhD, , PhD, , PhD, , MA & , PhD
Pages 139-154 | Received 02 Apr 2007, Accepted 08 Jun 2007, Published online: 10 Jul 2009

REFERENCES

  • Croft P, Burt J, Schollum J, Thomas E, Macfarlane G, Silman A. More pain, more tender points: Is fibromyalgia just one end of a continuous spectrum. Ann Rheum Dis 1996; 55: 482–485
  • Keating L, Lubke C, Powell V, Young T, Souvlis T, Jull G. Mid-thoracic tenderness: A comparison of pressure-pain threshold between spinal regions in asymptomatic subjects. Man Ther 2001; 6: 34–39
  • McCarberg B, Barkin R L, Wright J A, Cronan T A, Groessl E, Schmidt S M. Tender points as predictors of distress and the pharmacologic management of fibromyalgia syndrome. J Am Ther 2003; 10: 176–192
  • Lautenbacher S, Rollman G B, McCain G A. Multi-method assessment of experimental and clinical pain in patients with fibromyalgia. Pain 1994; 59: 45–53
  • Wolfe F. The relation between tender points and fibromyalgia symptom variables: Evidence that fibromyalgia is not a discrete disorder in the clinic. Ann Rheum Dis 1997; 56: 268–271
  • Croft P, Schollum J, Silman A. Population study of tender point counts and pain as evidence of fibromyalgia. BMJ 1994; 309: 696–699
  • Burckhardt C S, Clark S R, Bennett R M. The fibromyalgia impact questionnaire: Development and validation. J Rheumatol 1991; 18: 728–733
  • Wolfe F, Smythe H A, Yunus M B, Bennett R M, Bombardier C, Goldenberg D L, et al. The American College of Rheumatology 1990 criteria for the classification of fibromyalgia: Report of multicenter criteria committee. Arthritis Rheum 1990; 33: 160–172
  • Incel N A, Erden H R, Ozgocmen S, Catal S A, Yorgancioglu R. Pain pressure threshold values in ankylosing spondylitis. Rheumatol Int 2002; 22: 148–150
  • Catal S A, Erdem H R, Okumus M, Ozgocmen S, Yorgancioglu Z R. The measurement of pain-pressure threshold in patients with rheumatoid arthritis. The Pain Clinic 2000; 12: 187–191
  • Geisser M E, Gracely R H, Giesecke T, Petzke F W, Williams D A, Clauw D J. The association between experimental and clinical pain measures among persons with fibromyalgia and chronic fatigue syndrome. J Eur Pain 2007; 11: 202–207
  • Naliboff B D, Cohen M J. Psychophysical laboratory methods applied to clinical pain patients. Issues in pain measurement, C R Chapman, J D Loeser. Raven Press, New York 1989; 365–386
  • Petzke F, Clauw D J, Ambrose K, Khine A, Gracely R H. Increased pain sensitivity in fibromyalgia: Effects of stimulus type and mode of presentation. Pain 2003; 105: 403–413
  • Petzke F, Gracely R H, Park K M, Ambrose K, Clauw D J. What do tender points measure? Influence of distress on 4 measures of tenderness. J Rheumatol 2003; 30: 657–574
  • Maquet D, Croisier J L, Demoulin C, Crielaard J M. Pressure-pain thresholds of tender point sites in patients with fibromyalgia and in healthy controls. J Eur Pain 2004; 8: 111–117
  • Bendtsen L, Norregaard J, Jensen R, Olesen J. Evidence of qualitatively altered nociception in patients with fibromyalgia. Arthritis Rheum 1997; 40: 98–102
  • Gracely R H, Lota L, Walter D J, Dubner R. A multiple random staircase method of psychophysical pain assessment. Pain 1988; 32: 55–63
  • Granges G, Littlejohn G. Pressure-pain threshold in pain-free subjects, in patients with chronic regional pain syndromes, and in patients with fibromyalgia syndrome. Arthritis Rheum 1993; 36: 642–646
  • Kosek E, Ekholm J, Hansson P. Sensory dysfunction in fibromyalgia patients with implications for pathogenic mechanisms. Pain 1996; 68: 375–383
  • Lautenbacher S, Rollman G B. Possible deficiencies of pain modulation in fibromyalgia. J Clin Pain 1997; 13: 189–196
  • McDermid A J, Rollman G B, McCain G A. Generalized hypervigilance in fibromyalgia: Evidence of perceptual amplification. Pain 1996; 66: 133–144
  • Mikkelson M, Latikka P, Kautianen H, Isomeri R, Isomaki H. Muscle and bone pressure-pain threshold and pain tolerance in fibromyalgia patients and controls. Arch Phys Med Rehabil 1992; 73: 814–818
  • Petzke F, Khine A, Williams D, Groner K, Clauw D J, Gracely R H. Dolorimetry performed at 3 paired tender points highly predicts overall tenderness. J Rheumatol 2001; 28: 2568–2569
  • Quimby L G, Block S R, Gratwick G M. Fibromyalgia: generalized pain intolerance and manifold symptom reporting. J Rheumatol 1988; 15: 1264–1270
  • Scudds R A, Rollman G B, Harth M, McCain G A. Pain perception and personality measures as discriminators in the classification of fibrositis. J Rheumatol 1987; 14: 563–569
  • Sorensen J, Graven-Nielsen T, Henriksson K G, Bengtsson M, Arendt-Nielsen L. Hiperexcitability in fibromyalgia. J Rheumatol 1998; 25: 152–155
  • Wolfe F, Ross K, Anderson J, Russell I J, Herbert L. The prevalence and characteristics of fibromyalgia in the general population. Arthritis Rheum 1995; 38: 19–28
  • Petzke F, Harris R E, Williams D A, Clauw D J, Gracely R H. Differences in unpleasantness induced by experimental pressure pain between patients with fibromyalgia and healthy controls. J Eur Pain 2005; 9: 325–335
  • Campbell S M, Clark S, Tindall E A, Forehand M E, Bennett R M. Clinical characteristics of fibrositis I. A “blinded” controlled study of symptoms and tender points. Arthritis Rheum 1983; 26: 817–824
  • Carli G, Suman A L, Biasi G, Marcolongo R. Reactivity to superficial and deep stimuli in patients with chronic musculoskeletal pain. Pain 2002; 100: 259–269
  • Montoya P, Pauli P, Batra A, Wiedemann G. Altered processing of pain-related information in patients with fibromyalgia. J Eur Pain 2005; 9: 293–303
  • Simms R W, Goldenberg D L, Felson D T, Mason J H. Tenderness in 75 anatomic sites: Distinguishing fibromyalgia patients from controls. Arthritis Rheum 1988; 31: 182–187
  • Tunks E, Crook J, Norman G, Kalaher S. Tender points in fibromyalgia. Pain 1988; 34: 11–19
  • Huskisson E C, Hart F D. Pain threshold and arthritis. BMJ 1972; 4: 193–195
  • Gerecz-Simon E M, Tunks E R, Heale J A, Kean W F, Buchanan W W. Measurement of pain threshold in patients with rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and healthy controls. Clin Rheumatol 1989; 8: 467–474
  • Dhondt W, Willaeys T, Verbruggen L A, Oostendorp R A, Duquet W. Pain threshold in patients with rheumatoid arthritis and effect of manual oscillations. J Scand Rheumatol 1999; 28: 88–93
  • Song J, Noh S, Harth M, Merskey H. Relationship between pressure-pain threshold and coping strategies in patients with fibromyalgia. Pain Res Manag 1998; 3: 23–32
  • Greco C M, Rudy T H, Manzi S. Effects of a stress-reduction program on psychological function, pain and physical function of systemic lupus erythematosus patients: A randomized controlled trial. Arthritis Rheum 2004; 51: 625–634
  • Pérez M, López de la Osa A, Ballesteros F, Jiménez J, Godoy J. Dolorímetro Electrónico Portátil. Universidad de Granada. 2000, Patente. No. de solicitud: P200002517
  • García-Fernández E, Godoy-García J F, Jiménez-Alonso J, Godoy-Izquierdo D, Pérez-García M, López-Chicheri I. Reliability and validity of the pain threshold measurement with the Dolorímetro Electrónico Portátil® [Portable Electronic Dolorimeter] in healthy individuals and patients with musculoskeletal pain. The Pain Clinic 2006; 18: 377–386
  • Chesterton L S, Barlas P, Foster N E, Baxter G D, Wright C C. Gender differences in pressure-pain threshold in healthy humans. Pain 2003; 101: 259–266
  • Kosek E, Ekholm J, Nordemar R. A comparison of pressure-pain thresholds in different tissues and body regions. J Scand Rehabil Med 1993; 25: 117–124
  • Fillingim R B, Maixner W. Gender differences in the responses to noxious stimuli. Pain Forum 1995; 4: 209–221
  • Klonoff E A, Landrine H, Brown M. Appraisal and response to pain may be a function of its bodily location. J Psychosom Res 1993; 37: 661–670
  • Velle W. Sex differences in sensory functions. Perspect Biol Med 1987; 30: 491–522
  • Farrella M, Michelotti A, Cimino R, Martina R. An investigation of central and peripheral factors affecting pressure-pain thresholds on the human jaw muscles. J Musculoskelet Pain 1999; 7: 253–259
  • Isselee H, De Laat A, Bogaerts K, Lysens R. Short-term reproducibility of pressure-pain thresholds in masticatory muscles measured with a new algometer. J Orofac Pain 1998; 12: 203–209
  • Jensen K, Anderden H O, Olesen J, Lindblom U. Pressure-pain threshold in human temporal region. Evaluation of a new pressure algometer. Pain 1986; 25: 313–323
  • Ohrbach R, Gale E N. Pressure-pain thresholds, clinical assessment, and differential diagnosis: Reliability and validity in patients with myogenic pain. Pain 1989; 39: 157–169
  • Incel N A, Erdem H R, Acikgoz G, Ozgocmen S, Yorgancioglu Z R. Analysis of pain. Pressure threshold values in healthy subjects with repeated manual and algometric measures. Magy Rheumatol 1999; 40: 139–142
  • Fisher A A. Pressure algometry over normal muscles. Standard values, validity and reproducibility of pressure threshold. Pain 1987; 30: 115–126
  • Hogeweg J A, Langereis M J, Bernards A TM, Faber J AJ, Helders P JM. Algometry. Measuring pain threshold, method and characteristics in healthy subjects. J Scand Rehabil Med 1992; 24: 99–103
  • Torgen M, Swerup C. Individual factors and physical workload in relation to sensory thresholds in a middle-aged population sample. J Eur Appl Physiol 2002; 86: 418–427
  • López de la Osa A, Jiménez-Alonso J, García-Pérez M, Peralta-Ramírez M I, Gutiérrez-Cabello F. Grupo “Lupus Virgen de las Nieves”: Fibromyalgia in Spanish patients with systemic lupus erithomatosus. Lupus 1999; 8: 332–333
  • Grafe A, Wollina U, Tebbe B, Sprott H, Uhlemann C, Hein G. Fibromyalgia in lupus erythematosus. Acta Derm Venereol 1999; 79: 62–64
  • Forseth K O, Forre O, Gran J T. A 5.5 year prospective study of self-reported musculoskeletal pain and of fibromyalgia in a female population: Significance and natural history. Clin Rheumatol 1999; 18: 114–121
  • Pauli P, Wiedermann G, Nickola M. Pain sensitivity, cerebral laterality, and negative affect. Pain 1999; 80: 359–364
  • Arendt-Nielsen L, Graven-Nielsen T. Central sensitization in fibromyalgia and other musculoskeletal disorders. Curr Pain Headache Rep 2003; 7: 355–361
  • Coderre T J, Katz J, Vaccarino A L, Melzack R. Contribution of central neuroplasticity to pathological pain: Review of clinical and experimental evidence. Pain 1993; 52: 259–285
  • Desmeules J A, Cedraschi C, Rapiti E, Baumgartner E, Finckh A, Cohen P, et al. Neurophysiologic evidence for a central sensitisation in patients with fibromyalgia. Arthritis Rheum 2003; 48: 1420–1429
  • Diatchenko L, Slade G D, Nackely A G, Bhalang K, Sigurdsson A, Belfer I, et al. Genetic basis for individual variations in pain perception and the development of a chronic pain condition. Hum Mol Genet 2005; 14: 135–143
  • Dougherty P M, Palecek J, Paleckova V, Sorkin L S, Willis W D. The role of NMDA and non-NMDA excitatory amino acid receptors in the excitation of primate spinothalamic tract neurons by mechanical, chemical, thermal, and electrical stimuli. J Neurosci 1992; 12: 3025–3041
  • Geisser M E, Cassey K L, Brucksch C B, Ribbens C M, Appleton B B, Crofford L J. Perception of noxious and innocuous heat stimulation among healthy women and women with fibromyalgia: Association with mood, somatic focus, and catastrophizing. Pain 2003; 102: 243–250
  • Gracely R H, Petzke F, Wolf J M, Clauw D J. Functional magnetic resonance imaging evidence of augmented pain processing in fibromyalgia. Arthritis Rheum 2002; 46: 1333–1343
  • Graven-Nielsen L, Arendt-Nielsen T. Peripheral and central sensitization in musculoskeletal pain disorders: An experimental approach. Curr Rheumatol Rep 2002; 4: 313–321
  • Graven-Nielsen L, Arendt-Nielsen T. Central sensitization in fibromyalgia and other musculoskeletal disorders. Curr Pain Headache Rep 2003; 7: 355–361
  • Kosek E, Hansson P. Modulatory influence on somatosensory perception from vibration and heterotopic noxious conditioning stimulation [HNCS] in fibromyalgia patients and healthy subjects. Pain 1997; 70: 41–51
  • Mountz J M, Bradley L A, Alarcon G S. Abnormal functional activity of the central nervous system in fibromyalgia syndrome. J Am Med Sci 1998; 315: 385–396
  • Price D D, Mao J, Mayer D J. Central consequences of persistent pain states. Proceedings of the 8th World Congress on Pain. Progress in pain research and management, 8, T S Jensen, J A Turner, Z Wiesenfeld-Hallin. IASP Press, Seattle, WA 1997; 155–184
  • Staud R, Vierck C J, Cannon R L, Mauderli A P, Price D D. Abnormal sensitization and temporal summation of second pain [wind-up] in patients with fibromyalgia syndrome. Pain 2001; 91: 167–175
  • Kidd B L, Mapp P I, Blake D R, Gibson S J, Polak J M. Neurogenic influences in arthritis. Ann Rheum Dis 1990; 49: 649–652
  • Morris V H, Cruwys S C, Kidd B L. Characterisation of capsaicin-induced mechanical hyperalgesia as a marker for altered nociceptive processing in patients with rheumatoid arthritis. Pain 1997; 71: 223–227
  • Schaible H G, Ebersberger A, Von Banchet G S. Mechanism of pain in arthritis. NY Ann Acad Sci 2002; 966: 343–354
  • Kontinnen Y T, Kemppinen P, Segerberg M, Hukkanen M, Rees R, Santavirta S, et al. Peripheral and spinal neural mechanisms in arthritis, with particular reference to treatment of inflammation and pain. Arthritis Rheum 1994; 37: 965–982
  • Pillemer S R, Bradley L A, Crofford L J, Moldofsky H, Chrousos G P. The neuroscience and endocrinology of fibromyalgia. Arthritis Rheum 1997; 40: 1928–1939
  • Schaible H G, Grubb B D. Afferent and spinal mechanisms of joint pain. Pain 1993; 55: 5–54
  • Slosberg M. Spinal learning: Central modulation of pain processing and long-term alteration of interneuronal excitability as a result of nociceptive peripheral input. J Manipulative Physiol Ther 1990; 13: 326–335
  • Weigent D A, Bradley L A, Blalock J E, Alarcon G S. Current concepts in the pathophysiology of abnormal pain perception in fibromyalgia. J Am Med Sci 1998; 315: 405–412
  • Defrin R, Ronat A, Ravid A, Peretz C. Spatial summation of pressure pain: Effect of body region. Pain 2003; 106: 471–480
  • Nie H, Arendt-Nielsen L, Andersen H, Graven-Nielsen T. Temporal summation of pain evoked by mechanical stimulation in deep and superficial tissue. J Pain 2005; 6: 348–355
  • Sarlani E, Grace E G, Reynolds M A, Greenspan J D. Sex differences in temporal summation of pain and after sensations following repetitive noxious mechanical stimulation. Pain 2004; 109: 115–123
  • Price D D, Staud R, Robinson M E, Mauderli A P, Cannon R, Vierek C J. Enhanced temporal summation of second pain and its central modulation in fibromyalgia patients. Pain 2002; 99: 49–59
  • Staud R, Cannon R C, Mauderli A P, Robinson M E, Price D D, Vierck J C. Temporal summation of pain from mechanical stimulation of muscle tissue in normal controls and subjects with fibromyalgia syndrome. Pain 2003; 102: 87–95
  • Gracely R H, Grant M A, Giesecke T. Evoked pain measures in fibromyalgia. Best Pract Res Clin Rheumatol 2003; 17: 593–609
  • Staud R, Robinson M E, Vierck J C, Price D D. Diffuse noxious inhibitory controls [DNIC] attenuate temporal summation of second pain in normal males but not in normal females or fibromyalgia patients. Pain 2003; 101: 167–174

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.