Publication Cover
Journal of Environmental Science and Health, Part C
Environmental Carcinogenesis and Ecotoxicology Reviews
Volume 27, 2009 - Issue 4
426
Views
38
CrossRef citations to date
0
Altmetric
Original Articles

An Overview of Dioxin-Like Compounds, PCB, and Pesticide Exposures Associated with Sexual Differentiation of Neuroendocrine Systems, Fluctuating Asymmetry, and Behavioral Effects in Birds

, , , , &
Pages 286-300 | Received 22 Aug 2009, Accepted 21 Sep 2009, Published online: 30 Nov 2009

REFERENCES

  • Ottinger , M A and vom Saal , F S . 2002 . “ Impact of environmental endocrine disruptors on sexual differentiation in birds and mammals ” . In Hormones and Behavior in Higher Vertebrates , Edited by: Pfaff , D , Arnold , A , Etgen , A and Rubin , R . Vol. 4 , 325 – 383 . New York, NY : Academic Press .
  • Fox , G A . 1976 . Eggshell quality: Its ecological and physiological significance in a DDE-contaminated common tern population . The Wilson Bull , 88 ( 3 ) : 459
  • Rattner , B A , Clarke , R N and Ottinger , M A . 1986 . Depression of plasma luteinizing hormone concentration in quail by the anticholinesterase insecticide parathion . Comparative Biochemistry and Physiology , 83C : 451 – 453 .
  • Colborn , T , vom Saal , F S and Soto , A M . 1993 . Developmental effects of endocrine disrupting chemicals in wildlife and humans . Environmental Health Perspectives , 101 ( 5 ) : 378 – 384 .
  • Gray , L E Jr. , Ostby , J , Wolf , C , Lambright , C and Kelce , W . 1998 . The value of mechanistic studies in laboratory animals for the prediction of reproductive effects in wildlife: Endocrine effects on mammalian sexual differentiation . Environ Toxicol Chem , 17 : 109 – 118 .
  • Custer , T W , Custer , C M , Hines , R K , Gutreuter , S , Stromborg , K L , Allen , P D and Melancon , M J . 1999 . Organochlorine contaminants and reproductive success of double-crested cormorants from Green Bay, Wisconsin, USA . Environ Toxicol Chem , 18 ( 6 ) : 1209 – 1217 .
  • Custer , T W , Custer , C M and Hines , R K . 2002 . Dixoins and congener-specific polychlorinated biphenyls in three avian species from the Wisconsin River, Wisconsin . Environmental Pollution , 119 : 1 – 11 .
  • Kubiak , T J , Harris , H J Smith , L M . 1983 . Microcontaminants and reproductive impairment of the Forster's tern on Green Bay, Lake Michigan . Arch Environ Comtam Toxicol , 18 : 706 – 727 .
  • DeWitt , J C , Millsap , D S , Yeager , R L , Heise , S S , Sparks , D W and Henshel , D S . 2006 . External heart deformities in passerine birds exposed to environmental mixtures of polychlorinated biphenyls during development . Environ Toxicol Chem , 25 ( 2 ) : 541 – 551 .
  • Henshel , D S , Martin , J W , Norstrom , R , Whitehead , P , Steeves , J D and Cheng , K M . 1995 . Morphometric abnormalities in brains of Great Blue Heron hatchlings exposed in the wild to PCDDs . Environ Health Perspect , 103 ( 4 ) : 61 – 66 .
  • Martincovic , B , Bishop , C , Birmingham , E , Secord , A and Jock , K . 2003 . Health of tree swallow (Tachycineta bicolor) nestlings exposed to chlorinated hydrocarbons in the St. Lawrence River Basin. Part II. Basal and stress plasma corticosterone concentrations . J Toxicol Environ Health A , 66 : 2015 – 2029 .
  • Mayne , G J , Martin , P A , Bishop , C A and Boermans , H J . 2004 . Stress and immune response of nestling tree swallows (Tachycinete bicolor) and eastern bluebirds (Sialia sialis) exposed to non-persistent pesticides and p,p'-dichlorodiphyenydichloroethylene in apple orchards of southern Ontario, Canada . Environ Toxicol Chem , 23 : 2930 – 2940 .
  • Quinn , M , French , J B , McNabb , A F and Ottinger , M A . 2002 . The effects of polychorinated biphenyls (Aroclor 1242) on thyroxine, estradiol, molt, and plumage characteristics in the American Kestral (Falco sparverious) . Environmental Toxicology Chemistry , 21 ( 7 ) : 1417 – 1422 .
  • Quinn , M J Jr. , Sumitt , C L , Burrell , K and Ottinger , M A . 2005 . Fluctuating asymmetry and growth as biomarkers for exposure to androgen disrupting chemicals in Japanese quail . Ecotoxicology , 14 ( 6 ) : 637 – 643 .
  • Panzica , G C , Viglietti-Panzica , C , Mura , E , Quinn , M Jr. , Palanza , P and Ottinger , M A . 2007 . Effects of xenoestrogens and xenoandrogens on the differentiation of behaviorally relevant neural cicuits . Frontiers in Neuroendocrinology , 28 ( 4 ) : 179 – 200 .
  • Markman , S , Leitner , S Catchpole , C . 2008 . Pollutants increase song complexity and the volume of the brain area HVC in a songbird . PloS ONE , 3 ( 20 ) : e167
  • Hoogesteijn , A L , Kollias , G V , Quimby , F W , De Caprio Winkler , D W and De Voogd , T J . 2008 . Development of a brain nucleus involved in song production in zebra finches (Taeniopygia guttata) is disrupted by Aroclor 1248 . Environ Toxicol Chem , 27 ( 10 ) : 2071 – 2075 .
  • Boss , W R . 1943 . Hormonal determination of adult characters and sex behavior in herring gulls (Larus argentatus) . J Exp Zool , 94 : 181 – 209 .
  • Fry , D M and Toone , C K . 1981 . DDT-induced feminization of gull embryos . Science , 213 ( 4510 ) : 922 – 924 .
  • Fry , D M , Toone , C K , Speich , S M and Peard , R J . 1987 . Sex ratio skew and breeding patterns of gulls: demographic and toxicological considerations . Studies in Avian Biology , 10 : 26 – 43 .
  • Sanderson , T J . 2006 . The steroid hormone biosynthesis pathway as a target for endocrine-disrupting chemicals . Toxicolog Sci , 94 ( 1 ) : 3 – 21 .
  • Anway , M D and Skinner , M K . 2008 . Epigenetic programming of the germ line: effects of endocrine disruptors on the development of transgenerational disease . Reprod Biomed Online , 16 ( 1 ) : 23 – 25 .
  • Berg , C , Halldin , K , Fridolfson , A K , Brandt , I and Brunstrom , B . 1999 . The avian egg as a test system for endocrine disruptors: effects of diethylstilbestrol and ethynylestradiol on sex organ development . The Science of the Total Environment , 233 : 57 – 66 .
  • Tori , G M and Mayer , L P . 1981 . Effects of polychlorinated biphenyl on the metabolic rates of mourning doves exposed to low ambient temperatures . Bull Environ Contam Toxicol , 27 : 678 – 682 .
  • Fox , G A . 1992 . “ Epidemiological and pathobiological evidence of contaminant-induced alterations in sexual development in free-living wildlife ” . In Chemicallynduced Alterations in Sexual and Functional Development: The Wildlife/Human Connection , Edited by: Colborn , T and Clement , C . 147 – 158 . Princeton : Princeton Scientific Publishing .
  • Bishop , C A , Mahony , N A , Trudeau , S and Pettit , K E . 1999 . Reproductive success and biochemical effects in tree swallows (tachycineta bicolor) exposed to chlorinated hydrocarbon contaminants in wetlands of the great lakes and St. Lawrence River Basin, USA and Canada . Environ Toxicol Chem , 18 : 263 – 271 .
  • Grasman , K A and Fox , G A . 2001 . Associations between altered immune function and organochlorine contamination in young Caspian terns (Sterna caspia) from Lake Huron, 1997–1999 . Ecotoxicology , 10 : 101 – 114 .
  • Fox , G A , Jeffrey , D A , Williams , K S , Kennedy , S W and Grasman , K A . 2007 . Health of herring gulls (Larus argentatus) in relation to breeding location in the early 1990s. I. Biochemical measures . J Toxicol Environ Health Part A , 70 : 1443 – 1470 .
  • Fox , G A , Grasman , K A and Campbell , G D . 2007 . Health of herring gulls (Larus argentatus) in relation to breeding location in the early 1990s. II. Cellular and histopathological measures . J Toxicol Environ Health Part A , 70 : 1471 – 1491 .
  • Fox , G A , Gilman , A P , Peakall , D B and Anderka , F W . 1978 . Behavioral abnormalities of nesting Lake Ontario herring gulls . J Wildl Manage , 42 ( 3 ) : 477 – 483 .
  • Anway , M D and Skinner , M K . 2008 . Transgenerational effects of the endocrine disruptor vinclozolin on the prostate transcriptorme and adult onset disease . Prostate , 68 : 517 – 29 .
  • Anway , M D , Rekow , S S and Skinner , M K . 2008 . Transgenerational epigenetic programming of the embryonic estis transcriptome . Genomics , 91 : 30 – 40 .
  • Anway , M D and Skinner , M K . 2006 . Epigenetic transgenerational action of endocrine disruptors . Endocrinol , 147 ( Suppl. ) : S43 – 49 .
  • Crews , D , Willingham , E and Skipper , J K . 2000 . Endocrine disruptors: present issues, future directions . Quarterly Rev Biol , 75 ( 3 ) : 243 – 260 .
  • Eroschenko , V P , Amstislavsky , S Y Schwabel , H . 2002 . Altered behaviors in male mice, male quail, and salamander larvae following early exposures to the estrogenic pesticide methoxychlor . Neurotox Teratol , 24 ( 1 ) : 29 – 36 .
  • Iwaniuk , A N , Koperski , D T , Cheng , K M , Elliott , J E , Smith , L K , Wilson , L K and Wylie , D R . 2006 . The effects of environmental exposure to DDT on the brain of a songbird: changes in structures associated with mating and song . Behav Brain Res , 173 ( 1 ) : 1 – 10 .
  • Gill , H , Wilson , L K , Cheng , K M and Elliott , J E . 2003 . An assessment of DDT and other chlorinated compounds and the reproductive success of American robins (Turdus migratonrius) breeding in fruit orchards . Ecotoxicol , 12 : 113 – 23 .
  • Ottinger , M A , Abdelnabi , M A , Henry , P FP , McGary , S , Thompson , N and Wu , J . 2001 . Neuroendocrine and behavioral implications of endocrine disrupting chemicals in quail . Horm Behav , 40 : 234 – 247 .
  • Ottinger , M A , Wu , J M , Hazelton , J L , Abdelnabi , M A , Thompson , N , Quinn , M J Jr. , Donoghue , D , Schenk , F , Ruscio , M , Beavers , J and Jaber , M . 2005 . Assessing the consequences of the pesticide methoxychlor: Neuroendocrine and behavioral measures as indicators of biological impact of an estrogenic environmental chemical . Brain Research Bulletin , 65 ( 3 ) : 199 – 209 .
  • Halldin , K , Axelsson , J and Brunstrom , B . 2005 . Effects of endocrine modulators on sexual differentiation and reproductive function in male Japanese quail . Brain Res Bull , 65 ( 3 ) : 211 – 218 .
  • Quinn , M J Jr. , Summitt , C L and Ottinger , M A . 2006 . The effects of androgen disruption by DDE on the development and function of the immune system in Japanese quail . Immunopharm Immunotox , 28 : 535 – 544 .
  • Quinn , M J Jr. , McKernan , M , Lavoie , E and Ottinger , M A . 2007 . Immunotoxicity of trenbolone acetate in Japanese quail . J Toxicol Environ Health, Part A , 70 ( 1 ) : 88 – 93 .
  • Wade , J and Arnold , A P . 2004 . Sexual differentiation of the zebra finch song system . Ann NY Acad Sci , 1016 : 540 – 559 .
  • Breton , A R , Fox , G A and Chardine , J W . 2008 . Survival of adult herring gulls (Larus argentatus) from a Lake Ontario colony over two decades of environmental change . Waterbirds , 31 ( 1 ) : 15 – 23 .
  • Arnold , A P , Wade , J , Grisham , W , Jacobs , E C and Campagnoni , A T . 1996 . Sexual differentiation of the brain in songbirds . Dev Neurosci , 18 : 124 – 136 .
  • Adkins-Regan , E , Abdelnabi , M Mobarak , M . 1990 . Sex steroid levels in developing and adult male and female zebra finches (Poephila guttata) . Gen Comp Endocrinol , 78 : 93 – 109 .
  • Balthazart , J and Adkins-Regan , E . 2002 . “ Sexual differentiation of brain and behavior in birds ” . In Hormones and Behavior in Higher Vertebrates , Edited by: Pfaff , D , Arnold , A , Etgen , A and Rubin , R . Vol. 4 , 223 – 302 . New York, NY : Academic Press .
  • Gee , J M , Craig-Veit , C B and Millam , J R . 2004 . Posthatch methoxychlor exposure adversely affects reproduction of adult zebra finches, Taeniopygia guttata . Bull Environ Contam Toxicol , 73 ( 4 ) : 607 – 612 .
  • Satre , D , Reichert , M and Corbitt , C . 2009 . Effects of vinclozolin, an anti-androgen, on affiliative behavior in the dark-eyed junco, Junco hyemalis . Environ Res , 109 ( 4 ) : 400 – 404 .
  • Fry , M . 1995 . Reproductive effects in birds exposed to pesticides and industrial chemicals . Environ Health Perspect , 103 ( Suppl. 7 ) : 165 – 171 .
  • Grasman , K A , Scanlon , P F and Fox , G A . 1998 . Reproductive and physiological effects of environmental contaminants in fish-eating birds of the Great Lakes: A review of historical trends . Environ Monitoring Assessment , 53 ( 1 ) : 117 – 145 .
  • Golden , N H , Rattner , B A McGowan , P C . 2003 . Concentrations of metals in feathers and blood of nestling black-crowned night-herons (Nycticorax nycticorax) in Chesapeake and Delaware Bays . Bull Environ Contam Toxicol , 70 ( 2 ) : 385 – 393 .
  • McCarty , J P and Secord , A L . 1999 . Reproductive ecology of tree swallows (Tachycineta bicolor) with high levels of polychlorinated biphenyl contamination . Environ Toxicol Chem , 18 ( 7 ) : 1433 – 1439 .
  • Rattner , B A , Golden , N H and Ottinger , M A . 2000 . Contaminant exposure and effects in a terrestrial vertebrates database: Trends and data gaps for Atlantic coast estuaries . Environ Monitoring Assessment , 63 : 131 – 142 .
  • Abdelnabi , M A , Bakst , M R , Woods , J R and Ottinger , M A . 2000 . Plasma 17-β estradiol levels and ovarian interstitial cell structure in embryonic Japanese quail . Poultry Science , 79 : 564 – 567 .
  • Ottinger , M A and Bakst , M R . 1981 . Peripheral androgen concentrations and testicular morphology in embryonic and young male Japanese quail . Gen Comp Endocrinol , 43 : 170 – 177 .
  • Ottinger , M A , Pitts , S and Abdelnabi , M A . 2001 . Steroid hormones during embryonic development in Japanese quail: plasma, gonadal, and adrenal levels . Poultry Sci , 80 : 795 – 799 .
  • Adkins-Regan , E K , Ottinger , M A and Park , J . 1995 . Maternal transfer of estradiol to egg yolks alters sexual differentiation of avian offspring . J Exp Zool , 271 : 466 – 470 .
  • Lin , F , Wu , J , Abdelnabi , M A , Ottinger , M A and Guisti , M M . 2004 . Effects of dose and glycosylation on the transfer of genistein into the eggs of Japanese quail (Coturnix japonica) . J Agric Food Chem , 52 : 2397 – 2403 .
  • Ottinger , M A and Abdelnabi , M A . 1997 . Neuroendocrine systems and avian sexual differentiation . Amer Zool , 37 : 514 – 523 .
  • Ottinger , M A and Brinkley , H J . 1978 . The relationship of testosterone and sexual behavior during maturation of the male Japanese quail . Hormones and Behavior , 11 : 174 – 182 .
  • Igushi , T , Watanabe , H and Katsu , Y . 2007 . Toxicogenomics and ecotoxicogenomics for studying endocrine disruption and basic biology . Gen Comp Endocrinol , 153 ( 1–3 ) : 25 – 29 .
  • McKernan , M A , Rattner , B A , Hale , R C and Ottinger , M A . 2007 . Egg incubation position affects toxicity of air cell administered polychlorinated biphenyl 126 (3,3′,4,4′,5-pentachlorobiphenyl) in chicken (gallus gallus) embryos . Environ Toxicology Chemistry , 26 ( 12 ) : 2724 – 2727 .
  • McKernan , M A , Rattner , B A , Hale , R C and Ottinger , M A . 2008 . Toxicity of polybrominated diphenyl ethers (DE-71) in chicken (Gallus gallus), mallard (Anas platyrhynchos), and American kestrel (Falco sparverius) embryos and hatchlings . Environmental Toxicology Chem , 1 December 1 (Epub ahead of print)
  • Elliott , J E , Kennedy , S W and Lorenzen , A . 1997 . Comparative toxicity of polychlorinated biphenyls to Japanese quail (Coturnix c. japonica) and American kestrels . J Tox Environ Health , 51 : 57 – 75 .
  • Head , J A , Hahn , M E and Kennedy , S W . 2008 . Key amino acids in the aryl hydrocarbon receptor predict dioxin sensitivity in avian species . Environ Sci Technol , 1 ( 42 ) : 7535 – 7541 .
  • Perrin , F MR , Stacey , S , Burgess , A MC and Mittwoch , U . 1995 . A quantitative investigation of gonadal feminization by diethylstilboestrol of genetically male embryos of the quail Coturnix coturnix japonica . J Reprod Fertility , 103 : 223 – 226 .
  • McGary , S , Henry , P FP and Ottinger , M A . 2001 . Impact of vinclozolin exposure on Japanese quail reproduction . Environmental Toxicology Chemistry , 20 ( 11 ) : 2487 – 2493 .
  • Lien , R J , Cain , J R and Beasom , S L . 1987 . Effects of dietary and parenteral estrogens on bobwhite reproduction . Poultry Sci , 66 : 154 – 161 .
  • Barron , M G , Galbraith , H and Beltman , D . 1995 . Comparative reproductive and developmental toxicology of PCBs in birds . Comp Biochem Physiol , 112C : 1 – 14 .
  • Fox , L I and Grasman , K A . 1999 . Effects of PCB 126 on primary immune organ development in chicken embryos . Journal Toxicol Environ Health, Part A , 58 : 233 – 244 .
  • Karchner , S I , Franks , D G , Kennedy , S W and Hahn , M E . 2006 . The molecular basis for differential dioxin sensitivity in birds: role of the aryl hydrocarbon receptor . Proc Natl Acad Sci USA , 103 ( 16 ) : 6252 – 6257 .
  • Abdelnabi , M A and Ottinger , M A . 2003 . Hypothalamic indolamines during embryonic development and effects of steroid exposure . Gen Comp Endocrinol , 130 ( 1 ) : 13 – 19 .
  • Li , Q , Tamarkin , L , Levantine , P and Ottinger , M A . 1994 . Estradiol and androgen modulate chicken luteinizing hormone-releasing hormone-I release in vitro . Biol Reprod , 51 : 896 – 903 .
  • Ottinger , M A , Lavoie , E T , Thompson , N , Bohannon , M , Dean , K and Quinn , M J Jr. 2009 . Is the gonadotropin releasing hormone system vulnerable to endocrine disruption in birds? . Gen Comp Endocrinol , 163 : 104 – 108 .
  • Zoeller , R T . 2008 . Environmental neuroendocrine and thyroid disruption: relevance for reproductive medicine? . Fertil Steril , 89 ( 2 Suppl. ) : e99 – e100 .
  • NRC . 1999 . Hormonally Active Agents in the Environment , Washington, DC : National Academy Press .
  • Ottinger , M A , Abdelnabi , M , Li , Q , Chen , K , Tompson , N , Harada , N and Viglietti-Panzica , G C . 2004 . The Japanese quail: A model for studying reproductive aging of hypothalamic systems . Experimental Gerontology , 39 : 1679 – 1693 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.