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Research Article

Poly (propyleneimine) dendrimer based nanocontainers for targeting of efavirenz to human monocytes/macrophages in vitro

Research Paper

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Pages 89-98 | Received 12 May 2006, Accepted 21 Aug 2006, Published online: 08 Oct 2008

References

  • Andressen R, Picht J, Lohr GW. Primary cultures of human blood borne macrophages grown on hydrophobic teflon membranes. J Immunol Methods 1983; 56: 295–304
  • Ashton PR, Boyd SE, Brown CL, Nepogodier SA, Meijer EW, Peerlings HWI, Stoddart JF. Synthesis of glycodendrimers by modification of poly(propylene) imine dendrimers. Chem Eur J 1997; 3(6)974–984
  • Auger MJ, Ross JA. The natural immune system: The macrophage, CE Lewis, JOD Mcgee. Oxford University Press, New York 1992; 2–74
  • Bender AR, Von Briesen H, Kreuter J, Duncan IB, Rubsamen-Waigmann H. Efficiency of nanoparticles as carrier systems for antiviral agents in human immunodeficiency virus infected human monocytes/macrophages in vitro. Antimicrob Agents Chemother 1996; 40(6)1467–1471
  • Betageri GV, Black CDV, Szenbeni J, Wahl LM, Weinstein JN. Fc receptor mediated targeting of antibody bearing liposomes containing dideoxycytidine triphosphate to human monocyte/macrophages. J Pharm Pharmacol 1993; 45: 48–53
  • Bhadra D, Yadav AK, Bhadra S, Jain NK. Glycodendrimeric nanoparticulate carriers of primaquine phosphate for liver targeting. Int J Pharm 2005; 295: 221–233
  • De Brabender Van Den Berg EMM, Meijer EW. Poly (propylene) imine dendrimers. Large scale synthesis by heterogeneously catalyzed hydrogenation. Angew Chem Int Ed Eng 1993; 32(a)1308–1311
  • Fischer D, Li Y, Ahlemeyer B, Krieglstein J, Kissel T. In vitro cytotoxicity testing of polycations: Influence of polymer structure on cell viability and hemolysis. Biomaterials 2003; 24: 114–1131
  • Fridkin M, Tsubery H, Tzehoval E, Vonsover A, Biondi L, Filira, Rocchi R. Tuftsin AZT conjugate: Potential macrophage targeting for AIDS therapy. J Pept Sci 2005; 11: 37–44
  • Gartner S, Markovits P, Markovitz DM, Kaplan MH, Gallo RC, Popovic M. The role of mononuclear phagocytes in HTLV–III/LAV infection. Science 1986; 233: 215–219
  • Gordon S. Mononuclear phagocytes in immune defence. Immunology6th ed., I Roitt, J Brostoff, D Male. Mosby, Edinberg 2001; 153–157
  • Jansen JPGA, Brabender-Van Den Berg EMM, Meijer EW. Encapsulation of guest molecules into a dendritic box. Science 1994; 226: 1226–1229
  • Jevprasesphant R, Penny J, Jalal R, Attwood D, Mc Keown NB, D'Emanuel A. The influence of surface modification on the cytotoxicity of PAMAM dendrimers. Int J Pharm 2003; 252(1–2)263–266
  • Lee YC, Townsend RR, Harley MR, Lonngren J, Arnaep J, Haraldson M, Lonn H. Binding of synthetic oligosaccharide of hepatic Gal/GalNac lectin. Dependence on fine structure feature. J Biol Chem 1983; 258: 199–202
  • Levy JA. Pathogenesis of human immunodeficiency virus infection. Microbiol Rev 1993; 57: 183–289
  • Liu MJ, Frechet JMJ. Designing dendrimers for drug delivery. Pharm Sci Technol Today 1999; 2: 393–401
  • Malik N, Wiwattanapatapee R, Klopsch R, Lovenz K, Frey H, Weener JW, Meijer EW, Paulus W, Duncan R. Dendrimers relationship between structure and biocompatibility in vitro and preliminary studies on biodistribution of 125I labeled polyamidoamine dendrimers in vivo. J Control Release 2000; 65: 133–148
  • Marzolini C, Telenti A, Decosterd LA. Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1 infected patients. AIDS 2001; 15: 71–75
  • Mc Gann KA, Collman R, Kolson DL, Gonzalez-Scarano F, Coukos G, Coutifaris C, Strauss JF, Nathanson N. Human immunodeficiency virus type I causes productive infection of macrophages in primary placental cell cultures. J Infect Dis 1994; 169: 746–753
  • Miklis P, Cogin T, Goddard WA. Dynamics of Bengal rose encapsulated in Meijer's dendrimer box. J Am Chem Soc 1997; 119: 7458–7462
  • Milman G, Sharma O. Mechanism of HIV/SIV mucosal transmission. AIDS Res Hum Retroviruses 1994; 10: 1305–1312
  • Muller CD, Schuber F. Neomannosylated liposomes: Synthesis and interaction with mouse kuffer cells and resident peritoneal macrophages. Biochim Biophys Acta ser Biomembr 1989; 986: 97–105
  • Nicholson JK, Cross GD, Callaway CS, Mc Dougal JS. In vitro infection of human monocytes with human T-lymphotropic virus type III/lymphadenopathy associated virus (HTLV–III/LAV). J Immunol 1986; 137: 323–329
  • Nunez M, Gonzalez de Requena D, Gallego L. Higher efavirenz plasma levels correlate with development of insomonia. J Acquir Immuno Defic syndr 2001; 4(28)399–400
  • Sarasa-Nacenta M, Lupez-Pua Y, Lopez-Cortes LF, Mallolas J, Gatell JM, Carne X. Determination of efavirenz in human plasma by high performance liquid chromatography with ultraviolet detection. J Chromatogr B 2001; 763: 53–59
  • Schafer V, Von Briesen H, Andreesen R, Steffan AM, Royer C, Troster S, Kreuter J, Rubsamen-Waigmann H. Phagocytosis of nanoparticles by human immunodeficiency virus (HIV) infected macrophages: A possibility for antiviral drug targeting. Pharm Res 1992; 9(4)541–546
  • Shakthivel T, Florence AT. Dendrimers and dendrons: Facets of pharmaceutical nanotechnology. Drug Delivery Technol 2003; 3: 73–78
  • Staszewski S, Morates- Ramirez J, Tashima KT, Rachilis A, Skiest D, Stanford J, Stryker R, Johnson P, Labriola DF, Farinal D, Minion DJ, Ruiz NM. Efavirenz plus zidovudine and lamivudine, efavirenz plus indinavir and indinavir plus zidovudine and lamivudine in the treatment of HIV 1 infection in adults. N Engl J Med 1999; 341: 1865–1873
  • Tomalia DA. Birth of a new macromolecular architecture: Dendrimers as quantized building blocks for nanoscale synthetic organic chemistry. Aldrichimica ACTA 2004; 37(2)39–57
  • Von Briesen H, Andreesen R, Esser R, Brugger W, Meichisner C, Becker K, Rubsamen-Waigmann H. Infection of monocytes–marophages by HIV in vitro. Res Virol 1990; 141: 225–231
  • Weiss RA. How does HIV cause AIDS. Science 1993; 260: 1273–1279

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