Stimulation of human macrophages (THP-1) using Toll-like receptor-2 (TLR-2) agonist decorated nanocarriers

References

• Baggiolini M. (2001). Chemokines in pathology and medicine. J Intern Med, 250, 91–104.
   PubMed Web of Science ®Google Scholar
• Baudner CB, Morandi M, Giuliani MM, Verhoef JC, Junginger HE, Costantino P, Rappuoli R, Giudice GD. (2004). Modulation of immune response to group C meningococcal conjugate vaccine given intranasally to mice together with the LTK63 mucosal adjuvant and the trimethyl chitosan delivery system. J Infect Dis, 189, 828–832.
   PubMed Web of Science ®Google Scholar
• Bennett JV, De Castro FJ, Valdespino-Gomez JL, De Lourdes Garcia-Garcia M, Islas-Romero R, Echaniz-Aviles G, Jimenez-Corona A, Sepulveda-Amor J. (2002). Aerosolized measles and measles-rubella vaccines induce better measles antibody booster responses than injected vaccines: randomized trials in Mexican schoolchildren. Bull World Health Organ, 80, 806–812.
   PubMed Web of Science ®Google Scholar
• Bivas-Benita M, van Meijgaarden KE, Franken KLMC, Junginger HE, Borchard G, Ottenhoff THM, Geluk A. (2004). Pulmonary delivery of chitosan-DNA nanoparticles enhances the immunogenicity of a DNA vaccine encoding HLA-A*0201-restricted T-cell epitopes of Mycobacterium tuberculosis. Vaccine, 22, 1609–1615.
   PubMed Web of Science ®Google Scholar
• Bivas-Benita M, Ottenhoff TH, Junginger HE, Borchard G. (2005). Pulmonary DNA vaccination: concepts, possibilities and perspectives. J Control Release, 107, 1–29.
   PubMed Web of Science ®Google Scholar
• Bivas-Benita M, Lin M-Y, Bal SM, van Meijgaarden KE, Franken KL, Friggen AH, Junginger HE, Borchard G, Klein MR, Ottenhoff TH. (2009). Pulmonary delivery of DNA encoding Mycobacterium tuberculosis latency antigen Rv1733c associated to PLGA-PEI nanoparticles enhances T cell responses in a DNA prime/protein boost vaccination regimen in mice. Vaccine, 27, 4010–4017.
   PubMed Web of Science ®Google Scholar
• Blank F, Rothen-Rutishauser B, Gehr P. (2007). Dendritic cells and macrophages form a transepithelial network against foreign particulate antigens. Am J Respir Cell Mol Biol, 36, 669–677.
   PubMed Web of Science ®Google Scholar
• Dilraj A, Cutts FT, De Castro JF, Wheeler JG, Brown D, Roth C, Coovadia HM, Bennett JV. (2000). Response to different measles vaccine strains given by aerosol and subcutaneous routes to schoolchildren: a randomised trial. Lancet, 355, 798–803.
   PubMed Web of Science ®Google Scholar
• Forbes B, Ehrhardt C. (2005). Human respiratory epithelial cell culture for drug delivery applications. Eur J Pharm Biopharm, 60, 193–205.
   PubMed Web of Science ®Google Scholar
• Germershaus O, Mao S, Sitterberg J, Bakowsky U, Kissel T. (2008). Gene delivery using chitosan, trimethyl chitosan or polyethylenglycol-graft-trimethyl chitosan block copolymers: establishment of structure-activity relationships in vitro. J Control Release, 125, 145–154.
   PubMed Web of Science ®Google Scholar
• Hamman JH, Schultz CM, Kotzé AF. (2003). N-trimethyl chitosan chloride: optimum degree of quaternization for drug absorption enhancement across epithelial cells. Drug Dev Ind Pharm, 29, 161–172.
   PubMed Web of Science ®Google Scholar
• O’Hagan DT, Singh M, Ulmer JB. (2006) Microparticle-based technology for vaccines. Methods, 40, 10–19.
   PubMed Web of Science ®Google Scholar
• Heuking S, Iannitelli A, Di Stefano A, Borchard G. (2009). Toll-like receptor-2 agonist functionalized biopolymer for mucosal vaccination. Int J Pharm, doi: 10.1016/j.jim.2009.03.239. In press.
   PubMedGoogle Scholar
• Hu F-Q, Zhao MD, Yuan H, You J, Du Y-Z, Zeng S. (2006). A novel chitosan oligosaccharide-stearic acid micelles for gene delivery: properties and in vitro transfection studies. Int J Pharm, 315, 158–166.
   PubMed Web of Science ®Google Scholar
• Huang M, Fong CW, Khor E, Lim LY. (2005). Transfection efficiency of chitosan vectors: effect of polymer molecular weight and degree of deacetylation. J Control Release, 106, 391–406.
   PubMed Web of Science ®Google Scholar
• Iwasaki A, Medzhitov R. (2004). Toll-like receptor control of the adaptive immune responses. Nat Immunol, 5, 987–995.
   PubMed Web of Science ®Google Scholar
• Jintapattanakit A, Mao S, Kissel T, Junyaprasert VB. (2008). Physicochemical properties and biocompatibility of N-trimethyl chitosan: effect of quaternization and dimethylation. Eur J Pharm Biopharm, 70, 563–571.
   PubMed Web of Science ®Google Scholar
• Kleine B, Rapp W, Wiesmüller KH, Edinger M, Beck W, Metzger J, Ataulakhanov R, Jung G, Bessler WG. (1994). Lipopeptide-polyoxyethylene conjugates as mitogens and adjuvants. Immunobiology, 190, 53–66.
   PubMed Web of Science ®Google Scholar
• Lee CG, Da Silva CA, Lee JY, Hartl D, Elias JA. (2008). Chitin regulation of immune responses: an old molecule with new roles. Curr Opin Immunol, 20, 684–689.
   PubMed Web of Science ®Google Scholar
• van der Lubben IM, Verhoef JC, Borchard G, Junginger HE. (2001). Chitosan and its derivatives in mucosal drug and vaccine delivery. Eur J Pharm Sci, 14, 201–207.
   PubMed Web of Science ®Google Scholar
• Mansouri S, Cuie Y, Winnik F, Shi Q, Lavigne P, Benderdour M, Beaumont E, Fernandes JC. (2006). Characterization of folate-chitosan-DNA nanoparticles for gene therapy. Biomaterials, 27, 2060–2065.
   PubMed Web of Science ®Google Scholar
• Di Mario F, Rapanà P, Tomati U, Galli E. (2008). Chitin and chitosan from basidomycetes. Int J Biol Macromol, 43, 8–12.
   PubMed Web of Science ®Google Scholar
• Muzio M, Polentarutti N, Bosisio D, Prahladan MK, Mantovani A. (2000). Toll-like receptors: a growing family of immune receptors that are differentially expressed and regulated by different leukocytes. J Leukoc Biol, 67, 450–456.
   PubMed Web of Science ®Google Scholar
• Nishimura M, Naito S. (2005). Tissue-specific mRNA expression profiles of human toll-like receptors and related genes. Biol Pharm Bull, 28, 886–892.
   PubMed Web of Science ®Google Scholar
• Park CJ, Gabrielson NP, Pack DW, Jamison RD, Johnson AJW. (2009). The effect of chitosan on the migration of neutrophil-like HL60 cells mediated by IL-8. Biomaterials, 30, 436–444.
   PubMed Web of Science ®Google Scholar
• Sadik CD, Hunfeld K-P, Bachmann M, Kraiczy P, Eberhardt W, Brade V, Pfeilschifter J, Mühl H. (2008). Systematic analysis highlights the key role of TLR2/NF-κB/MAP kinase signaling for IL-8 induction by macrophage-like THP-1 cells under influence of Borrelia burgdorferi lysates. Int J Biochem Cell Biol, 40, 2508–2521.
   PubMed Web of Science ®Google Scholar
• Schnoor M, Buers I, Sietmann A, Brodde MF, Hofnagel O, Robenek H, Lorkowski S. (2009). Efficient non-viral transfection of THP-1 cells. J Immunol Methods, 344, 109–115.
   PubMed Web of Science ®Google Scholar
• Verheul RJ, Amidi M, van der Wal S, van Riet E, Jiskoot W, Hennink WE. (2008). Synthesis, characterization and in vitro biological properties of O-methyl free N,N,N-trimethylated chitosan. Biomaterials, 29, 3642–3649.
   PubMed Web of Science ®Google Scholar
• Wetzler LM. (2003). The role of Toll-like receptor 2 in microbial disease and immunity. Vaccine, 21, 55–60.
   Web of Science ®Google Scholar
• Zeng W, Jackson DC, Murray J, Rose K, Brown LE. (2000). Totally synthetic lipid-containing polyoxime peptide constructs are potent immunogens. Vaccine, 18, 1031–1039.
   PubMed Web of Science ®Google Scholar
• Zhang X, Chentoufi AA, Dasgupta G, Nesburn AB, Wu M, Zhu X, Carpenter D, Wechsler SL, You S, BenMohamed L. (2009). A genital tract peptide epitope vaccine targeting TLR-2 efficiently induces local and systemic CD8+ T cells and protects against herpes simplex virus type 2 challenge. Mucosal Immunol, 2, 129–143.
   PubMed Web of Science ®Google Scholar