The microRNA expression profiles in extracellular vesicles from HeLa cancer cells in response to cationic lipid- or polyethylenimine-mediated gene delivery

References

• Vader P, Mol EA, Pasterkamp G, et al. Extracellular vesicles for drug delivery. Adv Drug Deliv Rev. 2016;106:148–156.
   PubMed Web of Science ®Google Scholar
• Gopal SK, Greening DW, Rai A, et al. Extracellular vesicles: their role in cancer biology and epithelial-mesenchymal transition. Biochem J. 2017;474:21–45.
   PubMed Web of Science ®Google Scholar
• Maas SL, Breakefield XO, Weaver AM. Extracellular vesicles: unique intercellular delivery vehicles. Trends Cell Biol. 2017;27:172–188.
   PubMed Web of Science ®Google Scholar
• Pitt JM, Kroemer G, Zitvogel L. Extracellular vesicles: masters of intercellular communication and potential clinical interventions. J Clin Investig. 2016;126:1139–1143.
   PubMed Web of Science ®Google Scholar
• Shahabipour F, Barati N, Johnston TP, et al. Exosomes: nanoparticulate tools for RNA interference and drug delivery. J Cell Physiol. 2017;232:1660–1668.
   PubMed Web of Science ®Google Scholar
• Ha D, Yang N, Nadithe V. Exosomes as therapeutic drug carriers and delivery vehicles across biological membranes: current perspectives and future challenges. Acta Pharm Sin B. 2016;6:287–296.
   PubMed Web of Science ®Google Scholar
• Wu CY, Du SL, Zhang J, et al. Exosomes and breast cancer: a comprehensive review of novel therapeutic strategies from diagnosis to treatment. Cancer Gene Ther. 2017;24:6–12.
   PubMed Web of Science ®Google Scholar
• Tomasetti M, Lee W, Santarelli L, et al. Exosome-derived microRNAs in cancer metabolism: possible implications in cancer diagnostics and therapy. Exp Mol Med. 2017;49:e285.
   PubMed Web of Science ®Google Scholar
• Zhou Y, Zhou G, Tian C, et al. Exosome-mediated small RNA delivery for gene therapy. Wiley Interdiscip Rev RNA. 2016;7:758–771.
   PubMed Web of Science ®Google Scholar
• Guan S, Rosenecker J. Nanotechnologies in delivery of mRNA therapeutics using nonviral vector-based delivery systems. Gene Ther. 2017;24:133–143.
   PubMed Web of Science ®Google Scholar
• Hill AB, Chen M, Chen CK, et al. Overcoming gene-delivery hurdles: physiological considerations for nonviral vectors. Trends Biotechnol. 2016;34:91–105.
   PubMed Web of Science ®Google Scholar
• Pahle J, Walther W. Vectors and strategies for nonviral cancer gene therapy. Expert Opin Biol Ther. 2016;16:443–461.
   PubMed Web of Science ®Google Scholar
• Del Pozo-Rodríguez A, Solinís MÁ, Rodríguez-Gascón A. Applications of lipid nanoparticles in gene therapy. Eur J Pharm Biopharm. 2016;109:184–193.
   PubMed Web of Science ®Google Scholar
• Falagan-Lotsch P, Grzincic EM, Murphy CJ. New advances in nanotechnology-based diagnosis and therapeutics for breast cancer: An assessment of active-targeting inorganic nanoplatforms. Bioconjug Chem. 2017;28:135–152.
   PubMed Web of Science ®Google Scholar
• Wagner E. Polymers for nucleic acid transfer-an overview. Adv Genet. 2014;88:231–261.
   PubMed Web of Science ®Google Scholar
• Akhtar S. Cationic nanosystems for the delivery of small interfering ribonucleic acid therapeutics: a focus on toxicogenomics. Expert Opin Drug Metab Toxicol. 2010;6:1347–1362.
   PubMed Web of Science ®Google Scholar
• Beyerle A, Irmler M, Beckers J, et al. Toxicity pathway focused gene expression profiling of PEI-based polymers for pulmonary applications. Mol Pharm. 2010;7:727–737.
   PubMed Web of Science ®Google Scholar
• Lin CW, Jan MS, Kuo JH. Autophagy-related gene expression analysis of wild-type and Atg 5 gene knockout mouse embryonic fibroblast cells treated with polyethylenimine. Mol Pharmaceutics. 2014;11:3002–3008.
   PubMed Web of Science ®Google Scholar
• Lin CW, Jan MS, Kuo JH. Exploring microRNA expression profiles related to the mTOR signaling pathway in mouse embryonic fibroblast cells treated with polyethylenimine. Mol Pharm. 2015;12:2858–2868.
   PubMedGoogle Scholar
• Lin CW, Jan MS, Kuo JH. The vector-related influences of autophagic microRNA delivery by Lipofectamine 2000 and polyethylenimine 25K on mouse embryonic fibroblast cells. Eur J Pharm. Sci 2017;101:11–21.
   PubMed Web of Science ®Google Scholar
• Bolger AM, Lohse M, Usadel B. Trimmomatic: a flexible trimmer for Illumina sequence data. Bioinformatics. 2014;30:2114–2120.
   PubMed Web of Science ®Google Scholar
• Friedländer MR, MacKowiak SD, Li N, et al. MiRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. Nucleic Acids Res. 2012;40:37–52.
   PubMed Web of Science ®Google Scholar
• Langmead B, Trapnell C, Pop M, et al. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol. 2009;10:R25.
   PubMed Web of Science ®Google Scholar
• Love MI, Huber W, Anders S. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol. 2014;15:550.
   PubMed Web of Science ®Google Scholar
• Karagkouni D, Paraskevopoulou MD, Chatzopoulos S, et al. DIANA-TarBase v8: a decade-long collection of experimentally supported miRNA-gene interactions. Nucleic Acids Res. 2018;46:D239–D245.
   PubMed Web of Science ®Google Scholar
• Liu FL, Mo EP, Yang L, et al. Autophagy is involved in TGF-β1-induced protective mechanisms and formation of cancer-associated fibroblasts phenotype in tumor microenvironment. Oncotarget. 2016;7:4122–4141.
   PubMedGoogle Scholar
• Kosaka N, Yoshioka Y, Fujita Y, et al. Versatile roles of extracellular vesicles in cancer. J Clin Investig. 2016;126:1163–1172.
   PubMed Web of Science ®Google Scholar
• Kozielski KL, Rui Y, Green JJ. Non-viral nucleic acid containing nanoparticles as cancer therapeutics. Expert Opin Drug Deliv. 2016;13:1475–1487.
   PubMed Web of Science ®Google Scholar
• Omidi Y, Barar J, Akhtar S. Toxicogenomics of cationic lipid-based vectors for gene therapy: impact of microarray technology. Curr Drug Deliv. 2005;2:429–441.
   PubMedGoogle Scholar
• Lawson J, Dickman C, MacLellan S, et al. Selective secretion of microRNAs from lung cancer cells via extracellular vesicles promotes CAMK1D-mediated tube formation in endothelial cells. Oncotarget. 2017;8:83913–83924.
   PubMedGoogle Scholar
• Rodriguez M, Bajo-Santos C, Hessvik NP, et al. Identification of non-invasive miRNAs biomarkers for prostate cancer by deep sequencing analysis of urinary exosomes. Mol Cancer. 2017;16:156.
   PubMed Web of Science ®Google Scholar
• Su J, Liang H, Yao W, et al. MiR-143 and MiR-145 regulate IGF1R to suppress cell proliferation in colorectal cancer. PloS One. 2014;9:e114420.
   PubMed Web of Science ®Google Scholar
• Hummel R, Sie C, Watson D, et al. MicroRNA signatures in chemotherapy resistant esophageal cancer cell lines. World J Gastroenterol. 2014;20:14904–14912.
   PubMed Web of Science ®Google Scholar
• Mets E, Van der Meulen J, Van Peer G, et al. MicroRNA-193b-3p acts as a tumor suppressor by targeting the MYB oncogene in T-cell acute lymphoblastic leukemia. Leukemia. 2015;29:798–806.
   PubMed Web of Science ®Google Scholar
• Ganini D, Leinisch F, Kumar A, et al. Fluorescent proteins such as eGFP lead to catalytic oxidative stress in cells. Redox Biol. 2017;12:462–468.
   PubMed Web of Science ®Google Scholar