Transdermal delivery of celecoxib and α-linolenic acid from microemulsion-incorporated dissolving microneedles for enhanced osteoarthritis therapy

References

• Dolan AL, Hart DJ, Doyle DV, et al. The relationship of joint hypermobility, bone mineral density, and osteoarthritis in the general population: the Chingford Study. J Rheumatol. 2003;30(4):799–803.
   PubMed Web of Science ®Google Scholar
• Latourte A, Kloppenburg M, Richette P. Emerging pharmaceutical therapies for osteoarthritis. Nat Rev Rheumatol. 2020;16(12):673–688.
   PubMed Web of Science ®Google Scholar
• Mandl LA. Osteoarthritis year in review 2018: clinical. Osteoarthritis Cartilage. 2019;27(3):359–364.
   PubMed Web of Science ®Google Scholar
• Sacitharan PK. Ageing and osteoarthritis. Subcell Biochem. 2019;91:123–159.
   PubMedGoogle Scholar
• Taghizadeh Y, Chitsazan A, Pezeshki S, et al. Total ankle replacement along with subtalar joint arthrodesis: in-vitro and in-silico biomechanical investigations. Int J Numer Methods Biomed Eng. 2021;37(9):e3514.
   PubMed Web of Science ®Google Scholar
• Challoumas D, Biddle M, McLean M, et al. Comparison of treatments for frozen shoulder: a systematic review and meta-analysis. JAMA Netw Open. 2020;3(12):e2029581.
   PubMed Web of Science ®Google Scholar
• Krasselt M, Baerwald C. Celecoxib for the treatment of musculoskeletal arthritis. Expert Opin Pharmacother. 2019;20(14):1689–1702.
   PubMed Web of Science ®Google Scholar
• Sanghi S, MacLaughlin EJ, Jewell CW, et al. Cyclooxygenase-2 inhibitors: a painful lesson. Cardiovasc Hematol Disord Drug Targets. 2006;6(2):85–100.
   PubMedGoogle Scholar
• Puljak L, Marin A, Vrdoljak D, et al. Celecoxib for osteoarthritis. Cochrane Database Syst Rev. 2017;5(5):Cd009865.
   PubMedGoogle Scholar
• Yang D, Chen M, Sun Y, et al. Microneedle-mediated transdermal drug delivery for treating diverse skin diseases. Acta Biomater. 2021;121:119–133.
   PubMed Web of Science ®Google Scholar
• Prausnitz MR, Langer R. Transdermal drug delivery. Nat Biotechnol. 2008;26(11):1261–1268.
   PubMed Web of Science ®Google Scholar
• Vora LK, Moffatt K, Tekko IA, et al. Microneedle array systems for long-acting drug delivery. Eur J Pharm Biopharm. 2021;159:44–76.
   PubMed Web of Science ®Google Scholar
• McAlister E, Kirkby M, Domínguez-Robles J, et al. The role of microneedle arrays in drug delivery and patient monitoring to prevent diabetes induced fibrosis. Adv Drug Deliv Rev. 2021;175:113825.
   PubMed Web of Science ®Google Scholar
• Du H, Liu P, Zhu J, et al. Hyaluronic acid-based dissolving microneedle patch loaded with methotrexate for improved treatment of psoriasis. ACS Appl Mater Interfaces. 2019;11(46):43588–43598.
   PubMed Web of Science ®Google Scholar
• Zhou P, Chen C, Yue X, et al. Strategy for osteoarthritis therapy: Improved the delivery of triptolide using liposome-loaded dissolving microneedle arrays. Int J Pharm. 2021;609:121211.
   PubMedGoogle Scholar
• Zuo Z, Li M, Han T, et al. A platelet-cloaking tetramethylprazine-loaded microemulsion for improved therapy of myocardial ischaemia/reperfusion injury. J Drug Target. 2022;30(6):646–656.
   PubMed Web of Science ®Google Scholar
• Li Q, Liu X. Antiproliferative ability and fluorescence tracking of α-linolenic acid-loaded microemulsion as label-free delivery carriers in MDA-MB-231 cells. J Agric Food Chem. 2019;67(41):11518–11526.
   PubMed Web of Science ®Google Scholar
• Anand R, Kaithwas G. Anti-inflammatory potential of alpha-linolenic acid mediated through selective COX inhibition: computational and experimental data. Inflammation. 2014;37(4):1297–1306.
   PubMed Web of Science ®Google Scholar
• Lundin M, Elofsson UM, Blomberg E, et al. Adsorption of lysozyme, beta-casein and their layer-by-layer formation on hydrophilic surfaces: effect of ionic strength. Colloids Surf B Biointerfaces. 2010;77(1):1–11.
   PubMed Web of Science ®Google Scholar
• Mojeiko G, de Brito M, Salata GC, et al. Combination of microneedles and microemulsions to increase celecoxib topical delivery for potential application in chemoprevention of breast cancer. Int J Pharm. 2019;560:365–376.
   PubMedGoogle Scholar
• Qu D, Ma Y, Sun W, et al. Microemulsion-based synergistic dual-drug codelivery system for enhanced apoptosis of tumor cells. Int J Nanomedicine. 2015;10:1173–1187.
   PubMed Web of Science ®Google Scholar
• Guo M, Qu D, Qin Y, et al. Transferrin-functionalized microemulsions coloaded with coix seed oil and tripterine deeply penetrate to improve cervical cancer therapy. Mol Pharmaceutics. 2019;16(12):4826–4835.
   PubMed Web of Science ®Google Scholar
• Chen Y, Qu D, Fu R, et al. A Tf-modified tripterine-loaded coix seed oil microemulsion enhances anti-cervical cancer treatment. Int J Nanomedicine. 2018;13:7275–7287.
   PubMed Web of Science ®Google Scholar
• Qu D, He J, Liu C, et al. Triterpene-loaded microemulsion using coix lacryma-jobi seed extract as oil phase for enhanced antitumor efficacy: preparation and in vivo evaluation. Int J Nanomedicine. 2014;9:109–119.
   PubMed Web of Science ®Google Scholar
• Arshad MS, Zafar S, Zahra AT, et al. Fabrication and characterisation of self-applicating heparin sodium microneedle patches. J Drug Target. 2021;29(1):60–68.
   PubMed Web of Science ®Google Scholar
• Rabiei M, Kashanian S, Bahrami G, et al. Dissolving microneedle-assisted long-acting liraglutide delivery to control type 2 diabetes and obesity. Eur J Pharm Sci. 2021;167:106040.
   PubMed Web of Science ®Google Scholar
• Ziaei E, Emami J, Kazemi M, et al. Simultaneous determination of docetaxel and celecoxib in porous microparticles and rat plasma by liquid-liquid extraction and HPLC with UV detection: in vitro and in vivo validation and application. J Pharm Pharm Sci. 2020;23:289–303.
   PubMed Web of Science ®Google Scholar
• Liu B, Yan W. Quantitative polyunsaturated fatty acid analysis of chia seed oil by high-performance liquid chromatography. J Chromatogr Sci. 2021;59(2):120–127.
   PubMed Web of Science ®Google Scholar
• Wu T, Hou X, Li J, et al. Microneedle-mediated biomimetic cyclodextrin metal organic frameworks for active targeting and treatment of hypertrophic scars. ACS Nano. 2021;15(12):20087–20104.
   PubMed Web of Science ®Google Scholar
• Zhou F, Mei J, Han X, et al. Kinsenoside attenuates osteoarthritis by repolarizing macrophages through inactivating NF-κB/MAPK signaling and protecting chondrocytes. Acta Pharm Sin B. 2019;9(5):973–985.
   PubMed Web of Science ®Google Scholar
• Alkrad JA, Assaf SM, Hussein-Al-Ali SH, et al. Microemulsions as nanocarriers for oral and transdermal administration of enoxaparin. J Drug Delivery Sci Technol. 2022;70:103248.
   Web of Science ®Google Scholar
• Shin JA, Lee MY, Lee KT. Oxidation stability of O/W emulsion prepared with linolenic acid enriched diacylglycerol. J Food Sci. 2016;81(10):C2373–c2380.
   PubMed Web of Science ®Google Scholar
• Rabiei M, Kashanian S, Samavati SS, et al. Nanomaterial and advanced technologies in transdermal drug delivery. J Drug Target. 2020;28(4):356–367.
   PubMed Web of Science ®Google Scholar
• Nakanishi Y, Nakatsuji M, Seno H, et al. COX-2 inhibition alters the phenotype of tumor-associated macrophages from M2 to M1 in ApcMin/+ mouse polyps. Carcinogenesis. 2011;32(9):1333–1339.
   PubMed Web of Science ®Google Scholar