Association between the OXTR rs53576 genotype and latent profiles of post-traumatic stress disorder and depression symptoms in a representative sample of earthquake survivors

References

• Arletti, R., & Bertolini, A. (1987). Oxytocin acts as an antidepressant in two animal models of depression. Life Sciences, 41(14), 1725–1730. doi: 10.1016/0024-3205(87)90600-X
   PubMed Web of Science ®Google Scholar
• Blevins, C. A., Weathers, F. W., Davis, M. T., Witte, T. K., & Domino, J. L. (2015). The posttraumatic stress disorder checklist for DSM-5 (PCL-5): development and initial psychometric evaluation. Journal of Traumatic Stress, 28, 489–498. doi: 10.1002/jts.22059
   PubMed Web of Science ®Google Scholar
• Bradley, B., Westen, D., Mercer, K. B., Binder, E. B., Jovanovic, T., Crain, D., … Heim, C. (2011). Association between childhood maltreatment and adult emotional dysregulation in a low-income, urban, African American sample: Moderation by oxytocin receptor gene. Development and Psychopathology, 23(2), 439–452. doi:10.1017/S0954579411000162
   PubMed Web of Science ®Google Scholar
• Cao, X., Wang, L., Cao, C., Zhang, J., Liu, P., Zhang, B., … Elhai, J. D. (2015). Patterns of DSM-5 posttraumatic stress disorder and depression symptoms in an epidemiological sample of Chinese earthquake survivors: A latent profile analysis. Journal of Affective Disorders, 186( … ), 58–65. doi: 10.1016/j.jad.2015.06.058
   PubMed Web of Science ®Google Scholar
• Chen, F. S., Kumsta, R., von Dawans, B., Monakhov, M., Ebstein, R. P., & Heinrichs, M. (2011). Common oxytocin receptor gene (OXTR) polymorphism and social support interact to reduce stress in humans. Proceedings of the National Academy of Sciences, 108(50), 19937–19942. doi:10.1073/pnas.1113079108
   PubMed Web of Science ®Google Scholar
• Cohen, H., Kaplan, Z., Kozlovsky, N., Gidron, Y., Matar, M. A., & Zohar, J. (2010). Hippocampal microinfusion of oxytocin attenuates the behavioural response to stress by means of dynamic interplay with the glucocorticoid-catecholamine responses. Journal of Neuroendocrinology, 22(8), 889–904. doi: 10.1111/j.1365-2826.2010.02003.x
   PubMed Web of Science ®Google Scholar
• Contractor, A. A., Elhai, J. D., Fine, T. H., Tamburrino, M. B., Cohen, G., Shirley, E., … Calabrese, J. R. (2015). Latent profile analyses of posttraumatic stress disorder, depression and generalized anxiety disorder symptoms in trauma-exposed soldiers. Journal of Psychiatric Research, 68, 19–26. doi: 10.1016/j.jpsychires.2015.05.014
   PubMed Web of Science ®Google Scholar
• Dannlowski, U., Kugel, H., Grotegerd, D., Redlich, R., Opel, N., Dohm, K., … Ohrmann, P. (2016). Disadvantage of social sensitivity: Interaction of oxytocin receptor genotype and child maltreatment on brain structure. Biological Psychiatry, 80(5), 398–405. doi: 10.1016/j.biopsych.2015.12.010
   PubMed Web of Science ®Google Scholar
• Feldman, R., Monakhov, M., Pratt, M., & Ebstein, R. P. (2016). Oxytocin pathway genes: Evolutionary ancient system impacting on human affiliation, sociality, and psychopathology. Biological Psychiatry, 79(3), 174–184. doi: 10.1016/j.biopsych.2015.08.008
   PubMed Web of Science ®Google Scholar
• Frijling, J. L. (2017). Preventing PTSD with oxytocin: Effects of oxytocin administration on fear neurocircuitry and PTSD symptom development in recently trauma-exposed individuals. European Journal of Psychotraumatology, 8(1), 1302652. doi: 10.1080/20008198.2017.1302652
   PubMedGoogle Scholar
• Haagsma, J. A., Scholten, A. C., Andriessen, T. M., Vos, P. E., Van Beeck, E. F., & Polinder, S. (2015). Impact of depression and post-traumatic stress disorder on functional outcome and health-related quality of life of patients with mild traumatic brain injury. Journal of Neurotrauma, 32(11), 853–862. doi: 10.1089/neu.2013.3283
   PubMed Web of Science ®Google Scholar
• Koenen, K. C., Fu, Q. J., Ertel, K., Lyons, M. J., Eisen, S. A., True, W. R., … Tsuang, M. T. (2008). Common genetic liability to major depression and posttraumatic stress disorder in men. Journal of Affective Disorders, 105(1-3), 109–115. doi: 10.1016/j.jad.2007.04.021
   PubMed Web of Science ®Google Scholar
• Krueger, F., Parasuraman, R., Iyengar, V., Thornburg, M., Weel, J., Lin, M., … Lipsky, R. (2012). Oxytocin receptor genetic variation promotes human trust behavior. Frontiers in Human Neuroscience, 6, 4. doi: 10.3389/fnhum.2012.00004
   PubMed Web of Science ®Google Scholar
• Li, J., Zhao, Y., Li, R., Broster, L. S., Zhou, C., & Yang, S. (2015). Association of oxytocin receptor gene (OXTR) rs53576 polymorphism with sociality: A meta-analysis. Plos One, 10(6), e0131820. doi: 10.1371/journal.pone.0131820
   Web of Science ®Google Scholar
• Logue, M. W., Amstadter, A. B., Baker, D. G., Duncan, L., Koenen, K. C., Liberzon, I., … Smith, A. K. (2015). The psychiatric Genomics Consortium posttraumatic stress disorder Workgroup: Posttraumatic stress disorder enters the age of large-scale genomic collaboration. Neuropsychopharmacology, 40(10), 2287–2297. `. doi: 10.1038/npp.2015.118
   PubMed Web of Science ®Google Scholar
• Lucas-Thompson, R. G., & Holman, E. A. (2013). Environmental stress, oxytocin receptor gene (OXTR) polymorphism, and mental health following collective stress. Hormones & Behavior, 63(4), 615–624. doi: 10.1016/j.yhbeh.2013.02.015
   PubMed Web of Science ®Google Scholar
• McQuaid, R. J., McInnis, O. A., Matheson, K., & Anisman, H. (2015). Distress of ostracism: Oxytocin receptor gene polymorphism confers sensitivity to social exclusion. Social Cognitive and Affective Neuroscience, 10(8), 1153–1159. doi: 10.1093/scan/nsu166
   PubMed Web of Science ®Google Scholar
• Mcquaid, R. J., Mcinnis, O. A., Stead, J. D., Matheson, K., & Anisman, H. (2013). A paradoxical association of an oxytocin receptor gene polymorphism: Early-life adversity and vulnerability to depression. Frontiers in Neuroscience, 7(128), 128. doi: 10.3389/fnins.2013.00128
   PubMedGoogle Scholar
• Olff, M., Frijling, J. L., Kubzansky, L. D., Bradley, B., Ellenbogen, M. A., Cardoso, C., … van Zuiden, M. (2013). The role of oxytocin in social bonding, stress regulation and mental health: An update on the moderating effects of context and interindividual differences. Psychoneuroendocrinology, 38(9), 1883–1894. doi: 10.1016/j.psyneuen.2013.06.019
   PubMed Web of Science ®Google Scholar
• Radloff, L. S. (1977). The CES-D scale: A self-report depression scale for research in the general population. Applied Psychological Measurement, 1, 385–401. doi: 10.1177/014662167700100306
   Web of Science ®Google Scholar
• Rytwinski, N. K., Scur, M. D., Feeny, N. C., & Youngstrom, E. A. (2013). The co-occurrence of major depressive disorder among individuals with posttraumatic stress disorder: A meta-analysis. Journal of Traumatic Stress, 26, 299–309. doi: 10.1002/jts.21814
   PubMed Web of Science ®Google Scholar
• Saphirebernstein, S., Way, B. M., Kim, H. S., Sherman, D. K., & Taylor, S. E. (2011). Oxytocin receptor gene (OXTR) is related to psychological resources. Proceedings of the National Academy of Sciences of the United States of America, 108(37), 15118. doi: 10.1073/pnas.1113137108
   PubMed Web of Science ®Google Scholar
• Sartor, C. E., Grant, J. D., Lynskey, M. T., McCutcheon, V. V., Waldron, M., Statham, D. J., … Nelson, E. C. (2012). Common heritable contributions to low-risk trauma, high-risk trauma, posttraumatic stress disorder, and major depression. Archives of General Psychiatry, 69(3), 293–299. doi: 10.1001/archgenpsychiatry.2011.1385
   PubMed Web of Science ®Google Scholar
• Sasaki, J. Y., & Kim, H. S. (2017). Nature, nurture, and their interplay: A review of cultural neuroscience. Journal of Cross-Cultural Psychology, 48(1), 4–22. doi: 10.1177/0022022116680481
   Web of Science ®Google Scholar
• Sasaki, J. Y., Kim, H. S., Mojaverian, T., Kelley, L. D., Park, I. Y., & Janušonis, S. (2013). Religion priming differentially increases prosocial behavior among variants of the dopamine D4 receptor (DRD4) gene. Social Cognitive and Affective Neuroscience, 8(2), 209–215. doi: 10.1093/scan/nsr089
   PubMed Web of Science ®Google Scholar
• Sippel, L. M., Han, S., Watkins, L. E., Harpaz-Rotem, I., Southwick, S. M., Krystal, J. H., … Gelernter, J. (2017). Oxytocin receptor gene polymorphisms, attachment, and PTSD: Results from the National Health and Resilience in Veterans study. Journal of Psychiatric Research, 94, 139–147. doi: 10.1016/j.jpsychires.2017.07.008
   PubMed Web of Science ®Google Scholar
• Stein, M. B. (2018). Genomics of posttraumatic stress disorder: Sequencing stress and modeling misfortune. Biological Psychiatry, 83, 795–796. doi: 10.1016/j.biopsych.2017.05.001
   PubMed Web of Science ®Google Scholar
• Thompson, S. M., Hammen, C., Starr, L. R., & Najman, J. M. (2014). Oxytocin receptor gene polymorphism (rs53576) moderates the intergenerational transmission of depression. Psychoneuroendocrinology, 43, 11–19. doi: 10.1016/j.psyneuen.2014.01.012
   PubMed Web of Science ®Google Scholar
• Wang, Q., Shelton, R. C., & Dwivedi, Y. (2018). Interaction between early-life stress and FKBP5 gene variants in major depressive disorder and post-traumatic stress disorder: A systematic review and meta-analysis. Journal of Affective Disorders, 225, 422–428. doi: 10.1016/j.jad.2017.08.066
   PubMed Web of Science ®Google Scholar