Extracellular Angiogenic Growth Factor Interactions: An Angiogenesis Interactome Survey

REFERENCES

• Alon R., Cahalon L., Hershkoviz R., Elbaz D., Reizis B., Wallach D., Akiyama S. K., Yamada K. M., Lider O. TNF-alpha binds to the N-terminal domain of fibronectin and augments the beta 1-integrin-mediated adhesion of CD4+ T lymphocytes to the glycoprotein. Journal of Immunology 1994; 152: 1304–1313, [CSA]
   PubMed Web of Science ®Google Scholar
• Asplin I. R., Wu S. M., Mathew S., Bhattacharjee G., Pizzo S. V. Differential regulation of the fibroblast growth factor (FGF) family by alpha(2)-macroglobulin: Evidence for selective modulation of FGF-2-induced angiogenesis. Blood 2001; 97: 3450–3457, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Aviezer D., Cotton S., David M., Segev A., Khaselev N., Galili N., Gross Z., Yayon A. Porphyrin analogues as novel antagonists of fibroblast growth factor and vascular endothelial growth factor receptor binding that inhibit endothelial cell proliferation, tumor progression, and metastasis. Cancer Research 2000; 60: 2973–2980, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Barillari G., Gendelman R., Gallo R. C., Ensoli B. The Tat protein of human immunodeficiency virus type 1, a growth factor for AIDS Kaposi sarcoma and cytokine-activated vascular cells, induces adhesion of the same cell types by using integrin receptors recognizing the RGD amino acid sequence. Proceedings of the National Academy of Sciences of the United States of America 1993; 90: 7941–7945, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Barillari G., Sgadari C., Fiorelli V., Samaniego F., Colombini S., Manzari V., Modesti A., Nair B. C., Cafaro A., Sturzl M., et al. The Tat protein of human immunodeficiency virus type-1 promotes vascular cell growth and locomotion by engaging the alpha5beta1 and alphavbeta3 integrins and by mobilizing sequestered basic fibroblast growth factor. Blood 1999a; 94: 663–672, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Barillari G., Sgadari C., Palladino C., Gendelman R., Caputo A., Morris C. B., Nair B. C., Markham P., Nel A., Sturzl M., et al. Inflammatory cytokines synergize with the HIV-1 Tat protein to promote angiogenesis and Kaposi's sarcoma via induction of basic fibroblast growth factor and the alpha v beta 3 integrin. Journal of Immunology 1999b; 163: 1929–1935, [CSA]
   PubMed Web of Science ®Google Scholar
• Barleon B., Siemeister G., Martiny-Baron G., Weindel K., Herzog C., Marme D. Vascular endothelial growth factor up-regulates its receptor fms-like tyrosine kinase 1 (FLT-1) and a soluble variant of FLT-1 in human vascular endothelial cells. Cancer Research 1997; 57: 5421–5425, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Belotti D., Paganoni P., Manenti L., Garofalo A., Marchini S., Taraboletti G., Giavazzi R. Matrix metalloproteinases (MMP9 and MMP2) induce the release of vascular endothelial growth factor (VEGF) by ovarian carcinoma cells: Implications for ascites formation. Cancer Research 2003; 63: 5224–5229, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Bemelmans M. H., Gouma D. J., Buurman W. A. LPS-induced sTNF-receptor release in vivo in a murine model. Investigation of the role of tumor necrosis factor, IL-1, leukemia inhibiting factor, and IFN-gamma. Journal of Immunology 1993; 151: 5554–5562, [CSA]
   PubMed Web of Science ®Google Scholar
• Bergonzoni L., Caccia P., Cletini O., Sarmientos P., Isacchi A. Characterization of a biologically active extracellular domain of fibroblast growth factor receptor 1 expressed in Escherichia coli. European Journal of Biochemistry 1992; 210: 823–829, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Bhattacharjee G., Asplin I. R., Wu S. M., Gawdi G., Pizzo S. V. The conformation-dependent interaction of alpha 2-macroglobulin with vascular endothelial growth factor. A novel mechanism of alpha 2-macroglobulin/growth factor binding. Journal of Biological Chemistry 2000; 275: 26806–26811, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Bikfalvi A. Platelet factor 4: An inhibitor of angiogenesis. Seminars in Thrombosis and Hemostasis 2004; 30: 379–385, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Birkle S., Zeng G., Gao L., Yu R. K., Aubry J. Role of tumor-associated gangliosides in cancer progression. Biochimie 2003; 85: 455–463, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Bolser D., Dafas P., Harrington R., Park J., Schroeder M. Visualisation and graph-theoretic analysis of a large-scale protein structural interactome. BMC Bioinformatics 2003; 4: 45, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Bonner J. C., Badgett A., Hoffman M., Lindroos P. M. Inhibition of platelet-derived growth factor-BB-induced fibroblast proliferation by plasmin-activated alpha 2-macroglobulin is mediated via an alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein-dependent mechanism. Journal of Biological Chemistry 1995; 270: 6389–6395, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Bonnet H., Filhol O., Truchet I., Brethenou P., Cochet C., Amalric F., Bouche G. Fibroblast growth factor-2 binds to the regulatory beta subunit of CK2 and directly stimulates CK2 activity toward nucleolin. Journal of Biological Chemistry 1996; 271: 24781–24787, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Borges E., Jan Y., Ruoslahti E. Platelet-derived growth factor receptor beta and vascular endothelial growth factor receptor 2 bind to the beta 3 integrin through its extracellular domain. Journal of Biological Chemistry 2000; 275: 39867–39873, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Bornstein P., Armstrong L. C., Hankenson K. D., Kyriakides T. R., Yang Z. Thrombospondin 2, a matricellular protein with diverse functions. Matrix Biology 2000; 19: 557–568, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Bossard C., Van den Berghe L., Laurell H., Castano C., Cerutti M., Prats A. C., Prats H. Antiangiogenic properties of fibstatin, an extracellular FGF-2-binding polypeptide. Cancer Research 2004; 64: 7507–7512, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Bouvard D., Brakebusch C., Gustafsson E., Aszodi A., Bengtsson T., Berna A., Fassler R. Functional consequences of integrin gene mutations in mice. Circulation Research 2001; 89: 211–223, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Brat D. J., Bellail A. C., Van Meir E. G. The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis. Neuro-Oncology 2005; 7: 122–133, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Brooks P. C., Silletti S., von Schalscha T. L., Friedlander M., Cheresh D. A. Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity. Cell 1998; 92: 391–400, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Brown K. J., Parish C. R. Histidine-rich glycoprotein and platelet factor 4 mask heparan sulfate proteoglycans recognized by acidic and basic fibroblast growth factor. Biochemistry 1994; 33: 13918–13927, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Calabro L., Fonsatti E., Bellomo G., Alonci A., Colizzi F., Sigalotti L., Altomonte M., Musolino C., Maio M. Differential levels of soluble endoglin (CD105) in myeloid malignancies. Journal of Cellular Physiology 2003; 194: 171–175, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Camenisch G., Pisabarro M. T., Sherman D., Kowalski J., Nagel M., Hass P., Xie M. H., Gurney A., Bodary S., Liang X. H., et al. ANGPTL3 stimulates endothelial cell adhesion and migration via integrin alpha vbeta 3 and induces blood vessel formation in vivo. Journal of Biological Chemistry 2002; 277: 17281–17290, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Carlson T. R., Feng Y., Maisonpierre P. C., Mrksich M., Morla A. O. Direct cell adhesion to the angiopoietins mediated by integrins. Journal of Biological Chemistry 2001; 276: 26516–26525, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Carmeliet P., Jain R. K. Angiogenesis in cancer and other diseases. Nature 2000; 407: 249–257, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Casu B., Guerrini M., Guglieri S., Naggi A., Perez M., Torri G., Cassinelli G., Ribatti D., Carminati P., Giannini G., et al. Undersulfated and glycol-split heparins endowed with antiangiogenic activity. Journal of Medicinal Chemistry 2004; 47: 838–848, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Catlow K., Deakin J. A., Delehedde M., Fernig D. G., Gallagher J. T., Pavao M. S., Lyon M. Hepatocyte growth factor/scatter factor and its interaction with heparan sulphate and dermatan sulphate. Biochemical Society Transactions 2003; 31: 352–353, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Cavallaro U., Mariotti M., Wu Z. H., Soria M. R., Maier J. A. Fibronectin modulates endothelial response to HIV type 1 Tat. AIDS Research and Human Retroviruses 1997; 13: 1341–1348, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Chadderton N. S., Stringer S. E. Interaction of platelet factor 4 with fibroblast growth factor 2 is stabilised by heparan sulphate. International Journal of Biochemistry and Cell Biology 2003; 35: 1052–1055, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Chang F., Li R., Ladisch S. Shedding of gangliosides by human medulloblastoma cells. Experimental Cell Research 1997a; 234: 341–346, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Chang H. C., Samaniego F., Nair B. C., Buonaguro L., Ensoli B. HIV-1 Tat protein exits from cells via a leaderless secretory pathway and binds to extracellular matrix-associated heparan sulfate proteoglycans through its basic region. AIDS 1997b; 11: 1421–1431, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Christian S., Pilch J., Akerman M. E., Porkka K., Laakkonen P., Ruoslahti E. Nucleolin expressed at the cell surface is a marker of endothelial cells in angiogenic blood vessels. Journal of Cell Biology 2003; 163: 871–878, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Coltrini D., Rusnati M., Zoppetti G., Oreste P., Grazioli G., Naggi A., Presta M. Different effects of mucosal, bovine lung and chemically modified heparin on selected biological properties of basic fibroblast growth factor. Biochemical Journal 1994; 303(Pt 2)583–590, [INFOTRIEVE], [CSA]
   PubMedGoogle Scholar
• Comoglio P. M., Boccaccio C., Trusolino L. Interactions between growth factor receptors and adhesion molecules: Breaking the rules. Current Opinion in Cell Biology 2003; 15: 565–571, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Conforti G., Dominguez-Jimenez C., Zanetti A., Gimbrone M. A., Jr., Cremona O., Marchisio P. C., Dejana E. Human endothelial cells express integrin receptors on the luminal aspect of their membrane. Blood 1992; 80: 437–446, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Corso S., Comoglio P. M., Giordano S. Cancer therapy: Can the challenge be MET?. Trends in Molecular Medicine 2005; 11: 284–292, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Davis G. E., Senger D. R. Endothelial extracellular matrix: Biosynthesis, remodeling, and functions during vascular morphogenesis and neovessel stabilization. Circulation Research 2005; 97: 1093–1107, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• De Marchis F., Ribatti D., Giampietri C., Lentini A., Faraone D., Scoccianti M., Capogrossi M. C., Facchiano A. Platelet-derived growth factor inhibits basic fibroblast growth factor angiogenic properties in vitro and in vivo through its alpha receptor. Blood 2002; 99: 2045–2053, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Dennis P. A., Saksela O., Harpel P., Rifkin D. B. Alpha 2-macroglobulin is a binding protein for basic fibroblast growth factor. Journal of Biological Chemistry 1989; 264: 7210–7216, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Eliceiri B. P. Integrin and growth factor receptor crosstalk. Circulation Research 2001; 89: 1104–1110, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Eriksson A. E., Cousens L. S., Weaver L. H., Matthews B. W. Three-dimensional structure of human basic fibroblast growth factor. Proceedings of the National Academy of Sciences of the United States of America 1991; 88: 3441–3445, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Feige J. J., Negoescu A., Keramidas M., Souchelnitskiy S., Chambaz E. M. Alpha 2-macroglobulin: A binding protein for transforming growth factor-beta and various cytokines. Hormone Research 1996; 45: 227–232, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Fiorelli V., Barillari G., Toschi E., Sgadari C., Monini P., Sturzl M., Ensoli B. IFN-gamma induces endothelial cells to proliferate and to invade the extracellular matrix in response to the HIV-1 Tat protein: Implications for AIDS-Kaposi's sarcoma pathogenesis. Journal of Immunology 1999; 162: 1165–1170, [CSA]
   PubMed Web of Science ®Google Scholar
• Flaumenhaft R., Moscatelli D., Rifkin D. B. Heparin and heparan sulfate increase the radius of diffusion and action of basic fibroblast growth factor. Journal of Cell Biology 1990; 111: 1651–1659, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nature Medicine 1995; 1: 27–31, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Friedlander M., Brooks P. C., Shaffer R. W., Kincaid C. M., Varner J. A., Cheresh D. A. Definition of two angiogenic pathways by distinct alpha v integrins. Science 1995; 270: 1500–1502, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Fuh G., Garcia K. C., de Vos A. M. The interaction of neuropilin-1 with vascular endothelial growth factor and its receptor flt-1. Journal of Biological Chemistry 2000; 275: 26690–26695, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Gagnon M. L., Bielenberg D. R., Gechtman Z., Miao H. Q., Takashima S., Soker S., Klagsbrun M. Identification of a natural soluble neuropilin-1 that binds vascular endothelial growth factor: In vivo expression and antitumor activity. Proceedings of the National Academy of Sciences of the United States of America 2000; 97: 2573–2578, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Gao C. F., Vande Woude G. F. HGF/SF-Met signaling in tumor progression. Cell Research 2005; 15: 49–51, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Gengrinovitch S., Berman B., David G., Witte L., Neufeld G., Ron D. Glypican-1 is a VEGF165 binding proteoglycan that acts as an extracellular chaperone for VEGF165. Journal of Biological Chemistry 1999; 274: 10816–10822, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Gengrinovitch S., Greenberg S. M., Cohen T., Gitay-Goren H., Rockwell P., Maione T. E., Levi B. Z., Neufeld G. Platelet factor-4 inhibits the mitogenic activity of VEGF121 and VEGF165 using several concurrent mechanisms. Journal of Biological Chemistry 1995; 270: 15059–15065, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Goerges A. L., Nugent M. A. Regulation of vascular endothelial growth factor binding and activity by extracellular pH. Journal of Biological Chemistry 2003; 278: 19518–19525, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Goerges A. L., Nugent M. A. pH regulates vascular endothelial growth factor binding to fibronectin: A mechanism for control of extracellular matrix storage and release. Journal of Biological Chemistry 2004; 279: 2307–2315, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Gohring W., Sasaki T., Heldin C. H., Timpl R. Mapping of the binding of platelet-derived growth factor to distinct domains of the basement membrane proteins BM-40 and perlecan and distinction from the BM-40 collagen-binding epitope. European Journal of Biochemistry 1998; 255: 60–66, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Gospodarowicz D., Cheng J. Heparin protects basic and acidic FGF from inactivation. Journal of Cellular Physiology 1986; 128: 475–484, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Gupta K., Gupta P., Wild R., Ramakrishnan S., Hebbel R. P. Binding and displacement of vascular endothelial growth factor (VEGF) by thrombospondin: Effect on human microvascular endothelial cell proliferation and angiogenesis. Angiogenesis 1999; 3: 147–158, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Halden Y., Rek A., Atzenhofer W., Szilak L., Wabnig A., Kungl A. J. Interleukin-8 binds to syndecan-2 on human endothelial cells. Biochemical Journal 2004; 377: 533–538, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Hanahan D., Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 1996; 86: 353–364, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Handsley M. M., Edwards D. R. Metalloproteinases and their inhibitors in tumor angiogenesis. International Journal of Cancer 2005; 115: 849–860, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Hanneken A., Baird A. Soluble forms of the high-affinity fibroblast growth factor receptor in human vitreous fluid. Investigative Ophthalmology and Visual Science 1995; 36: 1192–1196, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Hanneken A., Maher P. A., Baird A. High affinity immunoreactive FGF receptors in the extracellular matrix of vascular endothelial cells–implications for the modulation of FGF-2. Journal of Cell Biology 1995; 128: 1221–1228, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Hayashi K., Madri J. A., Yurchenco P. D. Endothelial cells interact with the core protein of basement membrane perlecan through beta 1 and beta 3 integrins: An adhesion modulated by glycosaminoglycan. Journal of Cell Biology 1992; 119: 945–959, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Hendriks J., Planelles L., de Jong-Odding J., Hardenberg G., Pals S. T., Hahne M., Spaargaren M., Medema J. P. Heparan sulfate proteoglycan binding promotes APRIL-induced tumor cell proliferation. Cell Death and Differentiation 2005; 12: 637–648, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Heroult M., Bernard-Pierrot I., Delbe J., Hamma-Kourbali Y., Katsoris P., Barritault D., Papadimitriou E., Plouet J., Courty J. Heparin affin regulatory peptide binds to vascular endothelial growth factor (VEGF) and inhibits VEGF-induced angiogenesis. Oncogene 2004; 23: 1745–1753, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Hogg P. J., Hotchkiss K. A., Jimenez B. M., Stathakis P., Chesterman C. N. Interaction of platelet-derived growth factor with thrombospondin 1. Biochemical Journal 1997; 326(Pt 3)709–716, [INFOTRIEVE], [CSA]
   PubMedGoogle Scholar
• Hornig C., Barleon B., Ahmad S., Vuorela P., Ahmed A., Weich H. A. Release and complex formation of soluble VEGFR-1 from endothelial cells and biological fluids. Laboratory Investigation 2000; 80: 443–454, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Hsia E., Richardson T. P., Nugent M. A. Nuclear localization of basic fibroblast growth factor is mediated by heparan sulfate proteoglycans through protein kinase C signaling. Journal of Cellular Biochemistry 2003; 88: 1214–1225, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Hutchings H., Ortega N., Plouet J. Extracellular matrix-bound vascular endothelial growth factor promotes endothelial cell adhesion, migration, and survival through integrin ligation. Faseb Journal 2003; 17: 1520–1522, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Inoki I., Shiomi T., Hashimoto G., Enomoto H., Nakamura H., Makino K., Ikeda E., Takata S., Kobayashi K., Okada Y. Connective tissue growth factor binds vascular endothelial growth factor (VEGF) and inhibits VEGF-induced angiogenesis. Faseb Journal 2002; 16: 219–221, [INFOTRIEVE], [CSA]
   PubMedGoogle Scholar
• Iozzo R. V., San Antonio J. D. Heparan sulfate proteoglycans: Heavy hitters in the angiogenesis arena. Journal of Clinical Investigation 2001; 108: 349–355, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Iruela-Arispe M. L., Lombardo M., Krutzsch H. C., Lawler J., Roberts D. D. Inhibition of angiogenesis by thrombospondin-1 is mediated by 2 independent regions within the type 1 repeats. Circulation 1999; 100: 1423–1431, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Jia H., Lohr M., Jezequel S., Davis D., Shaikh S., Selwood D., Zachary I. Cysteine-rich and basic domain HIV-1 Tat peptides inhibit angiogenesis and induce endothelial cell apoptosis. Biochemical and Biophysical Research Communications 2001; 283: 469–479, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Jouan V., Canron X., Alemany M., Caen J. P., Quentin G., Plouet J., Bikfalvi A. Inhibition of in vitro angiogenesis by platelet factor-4-derived peptides and mechanism of action. Blood 1999; 94: 984–993, [INFOTRIEVE], [CSA]
   Google Scholar
• Ju B. H., Park B., Park J. H., Han K. Visualization and analysis of protein interactions. Bioinformatics 2003; 19: 317–318, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Kanematsu A., Marui A., Yamamoto S., Ozeki M., Hirano Y., Yamamoto M., Ogawa O., Komeda M., Tabata Y. Type I collagen can function as a reservoir of basic fibroblast growth factor. Journal of Control Release 2004; 99: 281–292, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Kato S., Ishii T., Hara H., Sugiura N., Kimata K., Akamatsu N. Hepatocyte growth factor immobilized onto culture substrates through heparin and matrigel enhances DNA synthesis in primary rat hepatocytes. Experimental Cell Research 1994; 211: 53–58, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Kemeny L., Szolnoky G., Kenderessy A. S., Gyulai R., Kiss M., Michel G., Nagy K., Ruzicka T., Dobozy A. Identification of a soluble interleukin-8 inhibitor in the supernatant of polymorphonuclear leukocytes. Immunology Letters 1998; 64: 23–29, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Kendall R. L., Wang G., Thomas K. A. Identification of a natural soluble form of the vascular endothelial growth factor receptor, FLT-1, and its heterodimerization with KDR. Biochemical and Biophysical Research Communications 1996; 226: 324–328, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Kessler O., Shraga-Heled N., Lange T., Gutmann-Raviv N., Sabo E., Baruch L., Machluf M., Neufeld G. Semaphorin-3F is an inhibitor of tumor angiogenesis. Cancer Research 2004; 64: 1008–1015, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Kim Y. M., Hwang S., Pyun B. J., Kim T. Y., Lee S. T., Gho Y. S., Kwon Y. G. Endostatin blocks vascular endothelial growth factor-mediated signaling via direct interaction with KDR/Flk-1. Journal of Biological Chemistry 2002; 277: 27872–27879, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Kobayashi T., Honke K., Miyazaki T., Matsumoto K., Nakamura T., Ishizuka I., Makita A. Hepatocyte growth factor specifically binds to sulfoglycolipids. Journal of Biological Chemistry 1994; 269: 9817–9821, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Kojima T., Katsumi A., Yamazaki T., Muramatsu T., Nagasaka T., Ohsumi K., Saito H. Human ryudocan from endothelium-like cells binds basic fibroblast growth factor, midkine, and tissue factor pathway inhibitor. Journal of Biological Chemistry 1996; 271: 5914–5920, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Koochekpour S., Merzak A., Pilkington G. J. Vascular endothelial growth factor production is stimulated by gangliosides and TGF-beta isoforms in human glioma cells in vitro. Cancer Letters 1996; 102: 209–215, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Kumar C. C. Integrin alpha v beta 3 as a therapeutic target for blocking tumor-induced angiogenesis. Current Drug Targets 2003; 4: 123–131, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Kumar C. C., Malkowski M., Yin Z., Tanghetti E., Yaremko B., Nechuta T., Varner J., Liu M., Smith E. M., Neustadt B., et al. Inhibition of angiogenesis and tumor growth by SCH221153, a dual alpha(v)beta3 and alpha(v)beta5 integrin receptor antagonist. Cancer Research 2001; 61: 2232–2238, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Kupprion C., Motamed K., Sage E. H. SPARC (BM-40, osteonectin) inhibits the mitogenic effect of vascular endothelial growth factor on microvascular endothelial cells. Journal of Biological Chemistry 1998; 273: 29635–29640, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Kurdowska A., Alden S. M., Noble J. M., Stevens M. D., Carr F. K. Involvement of alpha-2-macroglobulin receptor in clearance of interleukin 8-alpha-2-macroglobulin complexes by human alveolar macrophages. Cytokine 2000; 12: 1046–1053, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Kurosawa N., Kadomatsu K., Ikematsu S., Sakuma S., Kimura T., Muramatsu T. Midkine binds specifically to sulfatide the role of sulfatide in cell attachment to midkine-coated surfaces. European Journal of Biochemistry 2000; 267: 344–351, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMedGoogle Scholar
• LaMarre J., Wollenberg G. K., Gonias S. L., Hayes M. A. Cytokine binding and clearance properties of proteinase-activated alpha 2-macroglobulins. Laboratory Investigation 1991; 65: 3–14, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Lamszus K., Joseph A., Jin L., Yao Y., Chowdhury S., Fuchs A., Polverini P. J., Goldberg I. D., Rosen E. M. Scatter factor binds to thrombospondin and other extracellular matrix components. American Journal of Pathology 1996; 149: 805–819, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Lang Z., Guerrera M., Li R., Ladisch S. Ganglioside GD1a enhances VEGF-induced endothelial cell proliferation and migration. Biochemical and Biophysical Research Communication 2001; 282: 1031–1037, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Lantz M., Thysell H., Nilsson E., Olsson I. On the binding of tumor necrosis factor (TNF) to heparin and the release in vivo of the TNF-binding protein I by heparin. Journal of Clinical Investigation 1991; 88: 2026–2031, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Leali D., Belleri M., Urbinati C., Coltrini D., Oreste P., Zoppetti G., Ribatti D., Rusnati M., Presta M. Fibroblast growth factor-2 antagonist activity and angiostatic capacity of sulfated Escherichia coli K5 polysaccharide derivatives. Journal of Biological Chemistry 2001; 276: 37900–37908, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Lebrin F., Deckers M., Bertolino P., Ten Dijke P. TGF-beta receptor function in the endothelium. Cardiovascular Research 2005; 65: 599–608, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Li Z., Shimada Y., Uchida S., Maeda M., Kawabe A., Mori A., Itami A., Kano M., Watanabe G., Imamura M. TGF-alpha as well as VEGF, PD-ECGF and bFGF contribute to angiogenesis of esophageal squamous cell carcinoma. International Journal of Oncology 2000; 17: 453–460, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Lietha D., Chirgadze D. Y., Mulloy B., Blundell T. L., Gherardi E. Crystal structures of NK1-heparin complexes reveal the basis for NK1 activity and enable engineering of potent agonists of the MET receptor. EMBO Journal 2001; 20: 5543–5555, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Lin P., Buxton J. A., Acheson A., Radziejewski C., Maisonpierre P. C., Yancopoulos G. D., Channon K. M., Hale L. P., Dewhirst M. W., George S. E., et al. Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2. Proceedings of the National Academy of Sciences of the United States of America 1998; 95: 8829–8834, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Lindahl U., Lidholt K., Spillmann D., Kjellen L. More to “heparin” than anticoagulation. Thrombosis Research 1994; 75: 1–32, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Liu Y., Jones M., Hingtgen C. M., Bu G., Laribee N., Tanzi R. E., Moir R. D., Nath A., He J. J. Uptake of HIV-1 tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands. Nature Medicine 2000; 6: 1380–1387, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Lopez-Casillas F., Cheifetz S., Doody J., Andres J. L., Lane W. S., Massague J. Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-beta receptor system. Cell 1991; 67: 785–795, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Lowe-Krentz L. J., Thompson K., Patton W. A., 2nd. Heparin releasable and nonreleasable forms of heparan sulfate proteoglycan are found on the surfaces of cultured porcine aortic endothelial cells. Molecular and Celluar Biochemistry 1992; 109: 51–60, [CSA]
   PubMed Web of Science ®Google Scholar
• Lozano R. M., Redondo-Horcajo M., Jimenez M. A., Zilberberg L., Cuevas P., Bikfalvi A., Rico M., Gimenez-Gallego G. Solution structure and interaction with basic and acidic fibroblast growth factor of a 3-kDa human platelet factor-4 fragment with antiangiogenic activity. Journal of Biological Chemistry 2001; 276: 35723–35734, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Luque A., Carpizo D. R., Iruela-Arispe M. L. ADAMTS1/METH1 inhibits endothelial cell proliferation by direct binding and sequestration of VEGF165. Journal of Biological Chemistry 2003; 278: 23656–23665, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Lyon M., Deakin J. A., Mizuno K., Nakamura T., Gallagher J. T. Interaction of hepatocyte growth factor with heparan sulfate. Elucidation of the major heparan sulfate structural determinants. Journal of Biological Chemistry 1994; 269: 11216–11223, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Lyon M., Deakin J. A., Rahmoune H., Fernig D. G., Nakamura T., Gallagher J. T. Hepatocyte growth factor/scatter factor binds with high affinity to dermatan sulfate. Journal of Biological Chemistry 1998; 273: 271–278, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Lyon M., Rushton G., Gallagher J. T. The interaction of the transforming growth factor-betas with heparin/heparan sulfate is isoform-specific. Journal of Biological Chemistry 1997; 272: 18000–18006, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Marchio S., Alfano M., Primo L., Gramaglia D., Butini L., Gennero L., De Vivo E., Arap W., Giacca M., Pasqualini R., et al. Cell surface-associated Tat modulates HIV-1 infection and spreading through a specific interaction with gp120 viral envelope protein. Blood 2005; 105: 2802–2811, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Margosio B., Marchetti D., Vergani V., Giavazzi R., Rusnati M., Presta M., Taraboletti G. Thrombospondin 1 as a scavenger for matrix-associated fibroblast growth factor 2. Blood 2003; 102: 4399–4406, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Maroder M., Scarpa S., Screpanti I., Stigliano A., Meco D., Vacca A., Stuppia L., Frati L., Modesti A., Gulino A. Human immunodeficiency virus type 1 tat protein modulates fibronectin expression in thymic epithelial cells and impairs in vitro thymocyte development. Cellular Immunology 1996; 168: 49–58, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Marshall L. J., Perks B., Ferkol T., Shute J. K. IL-8 released constitutively by primary bronchial epithelial cells in culture forms an inactive complex with secretory component. Journal of Immunology 2001; 167: 2816–2823, [CSA]
   PubMed Web of Science ®Google Scholar
• Mawatari K., Liu B., Kent K. C. Activation of integrin receptors is required for growth factor-induced smooth muscle cell dysfunction. Journal of Vascular Surgery 2000; 31: 375–381, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• McArthur C. P., Wang Y., Heruth D., Gustafson S. Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53. Archives of Oral Biol 2001; 46: 545–555, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Caffrey T. A., Falcone D. J., Vicente D., Du B., Consigli S., Borth W. Protection of transforming growth factor-beta 1 activity by heparin and fucoidan. Journal of Cellular Physiology 1994; 159: 51–59, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Michieli P., Mazzone M., Basilico C., Cavassa S., Sottile A., Naldini L., Comoglio P. M. Targeting the tumor and its microenvironment by a dual-function decoy Met receptor. Cancer Cell 2004; 6: 61–73, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Migdal M., Huppertz B., Tessler S., Comforti A., Shibuya M., Reich R., Baumann H., Neufeld G. Neuropilin-1 is a placenta growth factor-2 receptor. Journal of Biological Chemistry 1998; 273: 22272–22278, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Mignatti P., Rifkin D. B. Plasminogen activators and matrix metalloproteinases in angiogenesis. Enzyme Protein 1996; 49: 117–137, [INFOTRIEVE], [CSA]
   PubMedGoogle Scholar
• Miralem T., Steinberg R., Price D., Avraham H. VEGF(165) requires extracellular matrix components to induce mitogenic effects and migratory response in breast cancer cells. Oncogene 2001; 20: 5511–5524, [INFOTRIEVE], [CSA], [CROSSREF]
   Google Scholar
• Mitola S., Soldi R., Zanon I., Barra L., Gutierrez M. I., Berkhout B., Giacca M., Bussolino F. Identification of specific molecular structures of human immunodeficiency virus type 1 Tat relevant for its biological effects on vascular endothelial cells. Journal of Virology 2000; 74: 344–353, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Mooradian D. L., Lucas R. C., Weatherbee J. A., Furcht L. T. Transforming growth factor-beta 1 binds to immobilized fibronectin. Journal of Cellular Biochemistry 1989; 41: 189–200, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Moroianu J., Riordan J. F. Nuclear translocation of angiogenin in proliferating endothelial cells is essential to its angiogenic activity. Proceedings of the National Academy of Sciences of the United States of America 1994; 91: 1677–1681, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Munger J. S., Harpel J. G., Giancotti F. G., Rifkin D. B. Interactions between growth factors and integrins: Latent forms of transforming growth factor-beta are ligands for the integrin alphavbeta1. Molecular Biology of the Cell 1998; 9: 2627–2638, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Munger J. S., Huang X., Kawakatsu H., Griffiths M. J., Dalton S. L., Wu J., Pittet J. F., Kaminski N., Garat C., Matthay M. A., et al. The integrin alpha v beta 6 binds and activates latent TGF beta 1: A mechanism for regulating pulmonary inflammation and fibrosis. Cell 1999; 96: 319–328, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Muramatsu H., Zou K., Sakaguchi N., Ikematsu S., Sakuma S., Muramatsu T. LDL receptor-related protein as a component of the midkine receptor. Biochemical and Biophysical Research Communications 2000; 270: 936–941, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Muramatsu H., Zou P., Suzuki H., Oda Y., Chen G. Y., Sakaguchi N., Sakuma S., Maeda N., Noda M., Takada Y., et al. alpha4beta1- and alpha6beta1-integrins are functional receptors for midkine, a heparin-binding growth factor. Journal of Cell Science 2004; 117: 5405–5415, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Murphy-Ullrich J. E., Schultz-Cherry S., Hook M. Transforming growth factor-beta complexes with thrombospondin. Molecular Biology of the Cell 1992; 3: 181–188, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Naldini A., Carraro F. Role of inflammatory mediators in angiogenesis. Current Drug Targets in Inflammation and Allergy 2005; 4: 3–8, [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Nesmelova I. V., Sham Y., Dudek A. Z., van Eijk L. I., Wu G., Slungaard A., Mortari F., Griffioen A. W., Mayo K. H. Platelet factor 4 and interleukin-8 CXC chemokine heterodimer formation modulates function at the quaternary structural level. Journal of Biological Chemistry 2005; 280: 4948–4958, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Neufeld G., Cohen T., Shraga N., Lange T., Kessler O., Herzog Y. The neuropilins: Multifunctional semaphorin and VEGF receptors that modulate axon guidance and angiogenesis. Trends in Cardiovascular Medicine 2002a; 12: 13–19, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Neufeld G., Kessler O., Herzog Y. The interaction of neuropilin-1 and neuropilin-2 with tyrosine-kinase receptors for VEGF. Advances in Experimental Medicine and Biology 2002b; 515: 81–90, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Norrby K. 2.5 kDa and 5.0 kDa heparin fragments specifically inhibit microvessel sprouting and network formation in VEGF165-mediated mammalian angiogenesis. International Journal of Experimental Pathology 2000; 81: 191–198, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Nyberg P., Xie L., Kalluri R. Endogenous inhibitors of angiogenesis. Cancer Research 2005; 65: 3967–3979, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• O'Connor-McCourt M. D., Wakefield L. M. Latent transforming growth factor-beta in serum. A specific complex with alpha 2-macroglobulin. Journal of Biological Chemisty 1987; 262: 14090–14099, [CSA]
   PubMed Web of Science ®Google Scholar
• Ogawa T., Takayama K., Takakura N., Kitano S., Ueno H. Anti-tumor angiogenesis therapy using soluble receptors: Enhanced inhibition of tumor growth when soluble fibroblast growth factor receptor-1 is used with soluble vascular endothelial growth factor receptor. Cancer and Gene Therapy 2002; 9: 633–640, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Orlev N., Shamir R., Shiloh Y. PIVOT: Protein interacions visualization tool. Bioinformatics 2004; 20: 424–425, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Ostman A. PDGF receptors-mediators of autocrine tumor growth and regulators of tumor vasculature and stroma. Cytokine and Growth Factor Reviews 2004; 15: 275–286, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Papaconstantinou M. E., Carrell C. J., Pineda A. O., Bobofchak K. M., Mathews F. S., Flordellis C. S., Maragoudakis M. E., Tsopanoglou N. E., Di Cera E. Thrombin functions through its RGD sequence in a non-canonical conformation. Journal of Biological Chemistry 2005; 280: 29393–29396, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Park D., Lee S., Bolser D., Schroeder M., Lappe M., Oh D., Bhak J. Comparative interactomics analysis of protein family interaction networks using PSIMAP (protein structural interactome map). Bioinformatics 2005; 21: 3234–3240, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Park J. E., Keller G. A., Ferrara N. The vascular endothelial growth factor (VEGF) isoforms: Differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF. Molecular Biology of the Cell 1993; 4: 1317–1326, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Patterson A. M., Gardner L., Shaw J., David G., Loreau E., Aguilar L., Ashton B. A., Middleton J. Induction of a CXCL8 binding site on endothelial syndecan-3 in rheumatoid synovium. Arthritis and Rheumatism 2005; 52: 2331–2342, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Pellegrini L. Role of heparan sulfate in fibroblast growth factor signalling: A structural view. Current Opinion in Structural Biology 2001; 11: 629–634, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Perollet C., Han Z. C., Savona C., Caen J. P., Bikfalvi A. Platelet factor 4 modulates fibroblast growth factor 2 (FGF-2) activity and inhibits FGF-2 dimerization. Blood 1998; 91: 3289–3299, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Pisano C., Aulicino C., Vesci L., Casu B., Naggi A., Torri G., Ribatti D., Belleri M., Rusnati M., Presta M. Undersulfated, low-molecular-weight glycol-split heparin as an antiangiogenic VEGF antagonist. Glycobiology 2005; 15: 1C–6C, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Plank M. J., Sleeman B. D., Jones P. F. The role of the angiopoietins in tumour angiogenesis. Growth Factors 2004; 22: 1–11, [INFOTRIEVE], [CSA], [CROSSREF]
   Google Scholar
• Polykratis A., Delbe J., Courty J., Papadimitriou E., Katsoris P. Identification of heparin affin regulatory peptide domains with potential role on angiogenesis. International Journal of Biochemistry and Cell Biology 2004; 36: 1954–1966, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Presta M., Dell'Era P., Mitola S., Moroni E., Ronca R., Rusnati M. Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis. Cytokine and Growth Factor Reviews 2005a; 16: 159–178, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Presta M., Leali D., Stabile H., Ronca R., Camozzi M., Coco L., Moroni E., Liekens S., Rusnati M. Heparin derivatives as angiogenesis inhibitors. Current Pharmaceutical Design 2003; 9: 553–566, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Presta M., Maier J. A., Rusnati M., Ragnotti G. Basic fibroblast growth factor is released from endothelial extracellular matrix in a biologically active form. Journal of Cell Physiology 1989; 140: 68–74, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Presta M., Oreste P., Zoppetti G., Belleri M., Tanghetti E., Leali D., Urbinati C., Bugatti A., Ronca R., Nicoli S., et al. Antiangiogenic activity of semisynthetic biotechnological heparins. Low-molecular-weight-sulfated Escherichia coli K5 polysaccharide derivatives as fibroblast growth factor antagonists. Arteriosclerosis, Thrombosis, and Vascular Biology 2005b; 25: 71–76, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Presta M., Rusnati M., Urbinati C., Sommer A., Ragnotti G. Biologically active synthetic fragments of human basic fibroblast growth factor (bFGF): Identification of two Asp-Gly-Arg-containing domains involved in the mitogenic activity of bFGF in endothelial cells. Journal of Cell Physiology 1991a; 149: 512–524, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Presta M., Rusnati M., Urbinati C., Statuto M., Ragnotti G. Functional domains of basic fibroblast growth factor. Possible role of Asp-Gly-Arg sequences in the mitogenic activity of bFGF. Annals of the New York Academy of Sciences 1991b; 638: 361–368, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Presta M., Rusnati M., Urbinati C., Tanghetti E., Statuto M., Pozzi A., Gualandris A., Ragnotti G. Basic fibroblast growth factor bound to cell substrate promotes cell adhesion, proliferation, and protease production in cultured endothelial cells. EXS 1992; 61: 205–209, [INFOTRIEVE], [CSA]
   PubMedGoogle Scholar
• Rahman S., Patel Y., Murray J., Patel K. V., Sumathipala R., Sobel M., Wijelath E. S. Novel hepatocyte growth factor (HGF) binding domains on fibronectin and vitronectin coordinate a distinct and amplified Met-integrin induced signalling pathway in endothelial cells. BMC Cell Biology 2005; 6: 8, [INFOTRIEVE], [CSA]
   PubMedGoogle Scholar
• Raines E. W., Lane T. F., Iruela-Arispe M. L., Ross R., Sage E. H. The extracellular glycoprotein SPARC interacts with platelet-derived growth factor (PDGF)-AB and -BB and inhibits the binding of PDGF to its receptors. Proceedings of the National Academy of Sciences of the United States of America 1992; 89: 1281–1285, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Raines E. W., Ross R. Compartmentalization of PDGF on extracellular binding sites dependent on exon-6-encoded sequences. Journal of Cell Biology 1992; 116: 533–543, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Reis R. C., Schuppan D., Barreto A. C., Bauer M., Bork J. P., Hassler G., Coelho-Sampaio T. Endostatin competes with bFGF for binding to heparin-like glycosaminoglycans. Biochemical and Biophysical Research Communications 2005; 333: 976–983, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Ribatti D. The crucial role of vascular permeability factor/vascular endothelial growth factor in angiogenesis: A historical review. British Journal of Haematology 2005; 128: 303–309, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Ribatti D., Leali D., Vacca A., Giuliani R., Gualandris A., Roncali L., Nolli M. L., Presta M. In vivo angiogenic activity of urokinase: Role of endogenous fibroblast growth factor-2. Journal of Cell Science 1999; 112(Pt 23)4213–4221, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Robinson C. J., Stringer S. E. The splice variants of vascular endothelial growth factor (VEGF) and their receptors. Journal of Cell Science 2001; 114: 853–865, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Roeckl W., Hecht D., Sztajer H., Waltenberger J., Yayon A., Weich H. A. Differential binding characteristics and cellular inhibition by soluble VEGF receptors 1 and 2. Experimental Cell Research 1998; 241: 161–170, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Ruegg C., Mariotti A. Vascular integrins: Pleiotropic adhesion and signaling molecules in vascular homeostasis and angiogenesis. Cellular and Molecular Life Sciences 2003; 60: 1135–1157, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Rusnati M., Camozzi M., Moroni E., Bottazzi B., Peri G., Indraccolo S., Amadori A., Mantovani A., Presta M. Selective recognition of fibroblast growth factor-2 by the long pentraxin PTX3 inhibits angiogenesis. Blood 2004; 104: 92–99, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Rusnati M., Coltrini D., Oreste P., Zoppetti G., Albini A., Noonan D., d'Adda di Fagagna F., Giacca M., Presta M. Interaction of HIV-1 Tat protein with heparin. Role of the backbone structure, sulfation, and size. Journal of Biological Chemistry 1997a; 272: 11313–11320, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Rusnati M., Oreste P., Zoppetti G., Presta M. Biotechnological engineering of heparin/heparan sulphate: A novel area of multi-target drug discovery. Current Pharmaceutical Design 2005; 11: 2489–2499, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Rusnati M., Presta M. Interaction of angiogenic basic fibroblast growth factor with endothelial cell heparan sulfate proteoglycans. Biological implications in neovascularization. International Journal of Clinical Laboratory Research 1996; 26: 15–23, [INFOTRIEVE], [CSA]
   PubMedGoogle Scholar
• Rusnati M., Tanghetti E., Dell'Era P., Gualandris A., Presta M. alphavbeta3 integrin mediates the cell-adhesive capacity and biological activity of basic fibroblast growth factor (FGF-2) in cultured endothelial cells. Molecular Biology of the Cell 1997b; 8: 2449–2461, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Rusnati M., Tanghetti E., Urbinati C., Tulipano G., Marchesini S., Ziche M., Presta M. Interaction of fibroblast growth factor-2 (FGF-2) with free gangliosides: Biochemical characterization and biological consequences in endothelial cell cultures. Molecular Biology of the Cell 1999a; 10: 313–327, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Rusnati M., Taraboletti G., Urbinati C., Tulipano G., Giuliani R., Molinari-Tossatti M. P., Sennino B., Giacca M., Tyagi M., Albini A., et al. Thrombospondin-1/HIV-1 tat protein interaction: Modulation of the biological activity of extracellular Tat. FASEB Journal 2000; 14: 1917–1930, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Rusnati M., Tulipano G., Spillmann D., Tanghetti E., Oreste P., Zoppetti G., Giacca M., Presta M. Multiple interactions of HIV-I Tat protein with size-defined heparin oligosaccharides. Journal of Biological Chemistry 1999b; 274: 28198–28205, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Rusnati M., Tulipano G., Urbinati C., Tanghetti E., Giuliani R., Giacca M., Ciomei M., Corallini A., Presta M. The basic domain in HIV-1 Tat protein as a target for polysulfonated heparin-mimicking extracellular Tat antagonists. Journal of Biological Chemistry 1998; 273: 16027–16037, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Rusnati M., Urbinati C., Caputo A., Possati L., Lortat-Jacob H., Giacca M., Ribatti D., Presta M. Pentosan polysulfate as an inhibitor of extracellular HIV-1 Tat. Journal of Biological Chemistry 2001; 276: 22420–22425, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Rusnati M., Urbinati C., Presta M. Internalization of basic fibroblast growth factor (bFGF) in cultured endothelial cells: Role of the low affinity heparin-like bFGF receptors. Journal of Cellular Physiology 1993; 154: 152–161, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Rusnati M., Urbinati C., Tanghetti E., Dell'Era P., Lortat-Jacob H., Presta M. Cell membrane GM1 ganglioside is a functional coreceptor for fibroblast growth factor 2. Proceedings of the National Academy of Sciences of the United States of America 2002; 99: 4367–4372, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Russo K., Ragone R., Facchiano A. M., Capogrossi M. C., Facchiano A. Platelet-derived growth factor-BB and basic fibroblast growth factor directly interact in vitro with high affinity. Journal of Biological Chemistry 2002; 277: 1284–1291, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Sachinidis A., Kraus R., Seul C., Meyer zu Brickwedde M. K., Schulte K., Ko Y., Hoppe J., Vetter H. Gangliosides GM1, GM2 and GM3 inhibit the platelet-derived growth factor-induced signalling transduction pathway in vascular smooth muscle cells by different mechanisms. European Journal of Cell Biology 1996; 71: 79–88, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Sahni A., Altland O. D., Francis C. W. FGF-2 but not FGF-1 binds fibrin and supports prolonged endothelial cell growth. Journal of Thrombosis and Haemostasis 2003; 1: 1304–1310, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Sahni A., Francis C. W. Vascular endothelial growth factor binds to fibrinogen and fibrin and stimulates endothelial cell proliferation. Blood 2000; 96: 3772–3778, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Sahni A., Francis C. W. Stimulation of endothelial cell proliferation by FGF-2 in the presence of fibrinogen requires alpha v beta3. Blood 2004; 104: 3635–3641, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Sahni A., Sahni S. K., Simpson-Haidaris P. J., Francis C. W. Fibrinogen binding potentiates FGF-2 but not VEGF induced expression of u-PA, u-PAR, and PAI-1 in endothelial cells. Journal of Thrombosis and Haemostasis 2004; 2: 1629–1636, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Said E. A., Courty J., Svab J., Delbe J., Krust B., Hovanessian A. G. Pleiotrophin inhibits HIV infection by binding the cell surface-expressed nucleolin. FEBS Journal 2005; 272: 4646–4659, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Sakata H., Stahl S. J., Taylor W. G., Rosenberg J. M., Sakaguchi K., Wingfield P. T., Rubin J. S. Heparin binding and oligomerization of hepatocyte growth factor/scatter factor isoforms. Heparan sulfate glycosaminoglycan requirement for Met binding and signaling. Journal of Biological Chemistry 1997; 272: 9457–9463, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Salmivirta M., Heino J., Jalkanen M. Basic fibroblast growth factor-syndecan complex at cell surface or immobilized to matrix promotes cell growth. Journal of Biological Chemistry 1992; 267: 17606–17610, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Sandhoff R., Grieshaber H., Djafarzadeh R., Sijmonsma T. P., Proudfoot A. E., Handel T. M., Wiegandt H., Nelson P. J., Grone H. J. Chemokines bind to sulfatides as revealed by surface plasmon resonance. Biochimica et Biophysica Acta 2005; 1687: 52–63, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Schoppet M., Chavakis T., Al-Fakhri N., Kanse S. M., Preissner K. T. Molecular interactions and functional interference between vitronectin and transforming growth factor-beta. Laboratory Investigation 2002; 82: 37–46, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Schuch G., Machluf M., Bartsch G., Jr., Nomi M., Richard H., Atala A., Soker S. In vivo administration of vascular endothelial growth factor (VEGF) and its antagonist, soluble neuropilin-1, predicts a role of VEGF in the progression of acute myeloid leukemia in vivo. Blood 2002; 100: 4622–4628, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Schuppan D., Schmid M., Somasundaram R., Ackermann R., Ruehl M., Nakamura T., Riecken E. O. Collagens in the liver extracellular matrix bind hepatocyte growth factor. Gastroenterology 1998; 114: 139–152, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Serini G., Valdembri D., Zanivan S., Morterra G., Burkhardt C., Caccavari F., Zammataro L., Primo L., Tamagnone L., Logan M., et al. Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function. Nature 2003; 424: 391–397, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Shoyab M., McDonald V. L., Byles C., Todaro G. J., Plowman G. D. Epithelins 1 and 2: Isolation and characterization of two cysteine-rich growth-modulating proteins. Proceedings of the National Academy of Sciences of the United States of America 1990; 87: 7912–7916, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Simons M., Horowitz A. Syndecan-4-mediated signalling. Cell Signaling 2001; 13: 855–862, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Soker S., Goldstaub D., Svahn C. M., Vlodavsky I., Levi B. Z., Neufeld G. Variations in the size and sulfation of heparin modulate the effect of heparin on the binding of VEGF165 to its receptors. Biochemistry and Biophysics Research Communication 1994; 203: 1339–1347, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Soker S., Miao H. Q., Nomi M., Takashima S., Klagsbrun M. VEGF165 mediates formation of complexes containing VEGFR-2 and neuropilin-1 that enhance VEGF165-receptor binding. Journal of Cellular Biochemistry 2002; 85: 357–368, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Soker S., Takashima S., Miao H. Q., Neufeld G., Klagsbrun M. Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 1998; 92: 735–745, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Soncin F. Angiogenin supports endothelial and fibroblast cell adhesion. Proceedings of the National Academy of Sciences of the United States of America 1992; 89: 2232–2236, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Soncin F., Strydom D. J., Shapiro R. Interaction of heparin with human angiogenin. Journal of Biological Chemistry 1997; 272: 9818–9824, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Spillmann D., Witt D., Lindahl U. Defining the interleukin-8-binding domain of heparan sulfate. Journal of Biological Chemistry 1998; 273: 15487–15493, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Sudhakar A., Sugimoto H., Yang C., Lively J., Zeisberg M., Kalluri R. Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by alpha v beta 3 and alpha 5 beta 1 integrins. Proceedings of the National Academy of Sciences of the United States of America 2003; 100: 4766–4771, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Sun J., Wang D. A., Jain R. K., Carie A., Paquette S., Ennis E., Blaskovich M. A., Baldini L., Coppola D., Hamilton A. D., et al. Inhibiting angiogenesis and tumorigenesis by a synthetic molecule that blocks binding of both VEGF and PDGF to their receptors. Oncogene 2005; 24: 4701–4709, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Takayama Y., May P., Anderson R. G., Herz J. Low density lipoprotein receptor-related protein 1 (LRP1) controls endocytosis and c-CBL-mediated ubiquitination of the platelet-derived growth factor receptor beta (PDGFR beta). Journal of Biological Chemistry 2005; 280: 18504–18510, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Take M., Tsutsui J., Obama H., Ozawa M., Nakayama T., Maruyama I., Arima T., Muramatsu T. Identification of nucleolin as a binding protein for midkine (MK) and heparin-binding growth associated molecule (HB-GAM). Journal of Biochemistry (Tokyo) 1994; 116: 1063–1068, [CSA]
   PubMed Web of Science ®Google Scholar
• Tanghetti E., Ria R., Dell'Era P., Urbinati C., Rusnati M., Ennas M. G., Presta M. Biological activity of substrate-bound basic fibroblast growth factor (FGF2): Recruitment of FGF receptor-1 in endothelial cell adhesion contacts. Oncogene 2002; 21: 3889–3897, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Taraboletti G., Belotti D., Borsotti P., Vergani V., Rusnati M., Presta M., Giavazzi R. The 140-kilodalton antiangiogenic fragment of thrombospondin-1 binds to basic fibroblast growth factor. Cell Growth and Differentiation 1997; 8: 471–479, [INFOTRIEVE], [CSA]
   PubMedGoogle Scholar
• Taraboletti G., Benelli R., Borsotti P., Rusnati M., Presta M., Giavazzi R., Ruco L., Albini A. Thrombospondin-1 inhibits Kaposi's sarcoma (KS) cell and HIV-1 Tat-induced angiogenesis and is poorly expressed in KS lesions. Journal of Pathology 1999; 188: 76–81, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Tarui T., Miles L. A., Takada Y. Specific interaction of angiostatin with integrin alpha(v)beta(3) in endothelial cells. Journal of Biological Chemistry 2001; 276: 39562–39568, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Taylor J. P., Cupp C., Diaz A., Chowdhury M., Khalili K., Jimenez S. A., Amini S. Activation of expression of genes coding for extracellular matrix proteins in Tat-producing glioblastoma cells. Proceedings of the National Academy of Sciences of the United States of America 1992; 89: 9617–9621, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Tessler S., Rockwell P., Hicklin D., Cohen T., Levi B. Z., Witte L., Lemischka I. R., Neufeld G. Heparin modulates the interaction of VEGF165 with soluble and cell associated flk-1 receptors. Journal of Biological Chemistry 1994; 269: 12456–12461, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Tezono K., Sarker K. P., Kikuchi H., Nasu M., Kitajima I., Maruyama I. Bioactivity of the vascular endothelial growth factor trapped in fibrin clots: Production of IL-6 and IL-8 in monocytes by fibrin clots. Haemostasis 2001; 31: 71–79, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Tiesman J., Hart C. E. Identification of a soluble receptor for platelet-derived growth factor in cell-conditioned medium and human plasma. Journal of Biological Chemistry 1993; 268: 9621–9628, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Tseng W. F., Huang S. S., Huang J. S. LRP-1/TbetaR-V mediates TGF-beta1-induced growth inhibition in CHO cells. FEBS Letters 2004; 562: 71–78, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Tufvesson E., Westergren-Thorsson G. Tumour necrosis factor-alpha interacts with biglycan and decorin. FEBS Letters 2002; 530: 124–128, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Turnbull J., Powell A., Guimond S. Heparan sulfate: Decoding a dynamic multifunctional cell regulator. Trends in Cell Biology 2001; 11: 75–82, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Tyagi M., Rusnati M., Presta M., Giacca M. Internalization of HIV-1 tat requires cell surface heparan sulfate proteoglycans. Journal of Biological Chemistry 2001; 276: 3254–3261, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Ueno H., Gunn M., Dell K., Tseng A., Jr., Williams L. A truncated form of fibroblast growth factor receptor 1 inhibits signal transduction by multiple types of fibroblast growth factor receptor. Journal of Biological Chemistry 1992; 267: 1470–1476, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Uetz P., Giot L., Cagney G., Mansfield T. A., Judson R. S., Knight J. R., Lockshon D., Narayan V., Srinivasan M., Pochart P., et al. A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature 2000; 403: 623–627, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Urbinati C., Bugatti A., Giacca M., Schlaepfer D., Presta M., Rusnati M. alpha v beta3-integrin-dependent activation of focal adhesion kinase mediates NF-kappa B activation and motogenic activity by HIV-1 Tat in endothelial cells. Journal of Cell Science 2005a; 118: 3949–3958, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Urbinati C., Mitola S., Tanghetti E., Kumar C., Waltenberger J., Ribatti D., Presta M., Rusnati M. Integrin alphavbeta3 as a target for blocking HIV-1 Tat-induced endothelial cell activation in vitro and angiogenesis in vivo. Arteriosclerosis Thrombosis and Vascular Biology 2005b; 25: 2315–2320, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Urbinati C., Bugatti A., Oreste P., Zoppetti G., Waltenberger J., Mitola S., Ribatti D., Presta M., Rusnati M. Chemically sulfated Escherichia coli K5 polysaccharide derivatives as extracellular HIV-1 Tat protein antagonists. FEBS Letters 2004; 568: 171–177, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Urbinati C., Mitola S., Tanghetti E., Kumar C., Waltenberger J., Ribatti D., Presta M., Rusnati M. Integrin aVb3 as a target for blocking HIV-1 Tat induced endothelial cell activation in vitro and angiogenesis in vivo. Arteriosclerosis, Thrombosis, and Vascular Biology 2005c, in press[CSA]
   Google Scholar
• Vilchis-Landeros M. M., Montiel J. L., Mendoza V., Mendoza-Hernandez G., Lopez-Casillas F. Recombinant soluble betaglycan is a potent and isoform-selective transforming growth factor-beta neutralizing agent. Biochemical Journal 2001; 355: 215–222, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Vlahakis N. E., Young B. A., Atakilit A., Sheppard D. The lymphangiogenic vascular endothelial growth factors VEGF-C and -D are ligands for the integrin alpha9beta1. Journal of Biological Chemistry 2005; 280: 4544–4552, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Vlodavsky I., Friedmann Y. Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis. Journal of Clinical Investigation 2001; 108: 341–347, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Vlodavsky I., Korner G., Ishai-Michaeli R., Bashkin P., Bar-Shavit R., Fuks Z. Extracellular matrix-resident growth factors and enzymes: Possible involvement in tumor metastasis and angiogenesis. Cancer and Metastasis Reviews 1990; 9: 203–226, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Vogel B. E., Lee S. J., Hildebrand A., Craig W., Pierschbacher M. D., Wong-Staal F., Ruoslahti E. A novel integrin specificity exemplified by binding of the alpha v beta 5 integrin to the basic domain of the HIV Tat protein and vitronectin. Journal of Cell Biology 1993; 121: 461–468, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Wajih N., Walter J., Sane D. C. Vascular origin of a soluble truncated form of the hepatocyte growth factor receptor (c-met). Circulation Research 2002; 90: 46–52, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Webb D. J., Atkins T. L., Crookston K. P., Burmester J. K., Qian S. W., Gonias S. L. Transforming growth factor beta isoform 2-specific high affinity binding to native alpha 2-macroglobulin. Chimeras identify a sequence that determines affinity for native but not activated alpha 2-macroglobulin. Journal of Biological Chemistry 1994; 269: 30402–30406, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• West D. C., Rees C. G., Duchesne L., Patey S. J., Terry C. J., Turnbull J. E., Delehedde M., Heegaard C. W., Allain F., Vanpouille C., et al. Interactions of multiple heparin binding growth factors with neuropilin-1 and potentiation of the activity of fibroblast growth factor-2. Journal of Biological Chemistry 2005; 280: 13457–13464, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Whitelock J. M., Murdoch A. D., Iozzo R. V., Underwood P. A. The degradation of human endothelial cell-derived perlecan and release of bound basic fibroblast growth factor by stromelysin, collagenase, plasmin, and heparanases. Journal of Biological Chemistry 1996; 271: 10079–10086, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Xu Y., Liu Y. J., Yu Q. Angiopoietin-3 is tethered on the cell surface via heparan sulfate proteoglycans. Journal of Biological Chemistry 2004; 279: 41179–41188, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Yamazaki Y., Matsunaga Y., Nakano Y., Morita T. Identification of VEGF receptor-binding protein in the venom of eastern cottonmouth: A new role of snake venom myotoxic Lys49-phospholipase A2. Journal of Biological Chemistry 2005; 280: 29989–29992, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Yang S. P., Kwon B. O., Gho Y. S., Chae C. B. Specific interaction of VEGF165 with beta-amyloid, and its protective effect on beta-amyloid-induced neurotoxicity. Journal of Neurochemistry 2005; 93: 118–127, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Zhang N., Deuel T. F. Pleiotrophin and midkine, a family of mitogenic and angiogenic heparin-binding growth and differentiation factors. Current Opinion in Hematology 1999; 6: 44–50, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Zioncheck T. F., Richardson L., Liu J., Chang L., King K. L., Bennett G. L., Fugedi P., Chamow S. M., Schwall R. H., Stack R. J. Sulfated oligosaccharides promote hepatocyte growth factor association and govern its mitogenic activity. Journal of Biological Chemistry 1995; 270: 16871–16878, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar