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Original Articles

An Approach for Visualization of the Active Site of Enzymes with Unknown Three-Dimensional Structures

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Pages 345-358 | Received 30 Jun 2000, Accepted 26 Dec 2000, Published online: 24 Sep 2006

References

  • Norinder , U. 1995 . “ The advantages of using rational drug design in modern drug discovery: How to integrate computer-aided drug design and modern biotechnology. In ” . In Computer-Aided Drug Design Industrial Research , Edited by: Herrmann , E. C. and Franke , R. 99 – 109 . Berlin : Springer Verlag .
  • Martin , Y. C. 1998 . “ current state, scope, and limitation. ” . In 3D QSAR in drug design: recent advances. , Edited by: Kubinyi , H. , Folkers , G. and Martin , Y. C. Vol. 12/13/14 , 3 – 23 . Kluwer/ Escom . 3D QSAR
  • Kim , K. H. 1995 . “ Comparative molecular field analysis (CoMFA). ” . In Molecular similarity in drug design. , Edited by: Dean , P. M. 291 – 331 . London : Blackie Academic & Professional .
  • Berry , M. D. , Juorio , A. V. and Paterson , I. A. 1994 . The functional role of monoamine oxidases A and B in the mammalian central nervous system . Progress in Neurobiology , 42 : 375 – 391 .
  • Laux , G. , Volz , H.-P. and Moller , H.-J. 1995 . Newer and older monoamine oxidase inhibitors. A comparative profile . CNS Drugs , 3 : 145 – 158 .
  • 1699 . Tripos Inc , Missuori, 63144, , USA : South Haniey Road, St. Louis . Sybyl 6.5
  • Ivanov , A. S. , Skvortsov , V. S. , Tikhonova , O. V. , Veselovsky , A. V. and Archakov , A. I. 20–24 July 1998 1998 . “ Database mining for ligands of drug oxidizing enzymes: The ways in binding site description. ” . In 12 Internat. Symp. on Micorosomes and Drug Oxidations 20–24 July , 259 Montpellier, , France
  • Tipton , K. F. and Youdim , M. B. H. 1976 . “ Assay of monoamine oxidase. ” . In Monoamine oxidase and its inhibition. , Edited by: Wolstenholm , G. E. W. and Knight , J. 393 – 403 . Amsterdam : Elsevier .
  • Medvedev , A. E. , Kirkel , A. Z. , Kamyshanskaya , N. S. , Moskvitina , T. A. , Axenova , L. N. , Gorkin , V. Z. , Andreeva , N. I. , Golovina , S. M. and Mashkovsky , M. D. 1994 . Monoamine oxidase inhibition by novel antidepressant tetrindole . Biochem. Pharmacol. , 47 : 303 – 308 .
  • Da Prada , M. , Kettler , R. , Keller , H. H. , Burkland , W. P. and Haefely , W. E. 1989 . Preclinical profiles of the novel reversible MAO-A inhibitors, moclobemide and brofaromine, in comparison with irreversible MAO inhibitors. . J Neural Transm. , 28 : 5 – 20 . (Suppl)
  • http://lmgdd.ibmh.msk.su/KeyLock
  • Wlodawer , A. and Vondrasek , J. 1998 . Inhibitors of HIV-1 protease: a major success of structure-assisted drug design . Annu. Rev. Biophys. Biomol. Struct. , 27 : 249 – 284 .
  • Medvedev , A. E. , Ivanov , A. S. , Veselovsky , A. V. , Skvortsov , V. S. and Archakov , A. I. 1996 . QSAR analysis of indole analogues as monoamine oxidase inhibitors . J. Chem. Inf. Comput. Sci. , 36 : 664 – 671 .
  • Harfenist , M. , Joyner , C. T. , Mize , P. D. and White , H. L. 1994 . Selective inhibitors of monoamine oxidase. Arylamide SAR . J. Med. Chem. , 37 : 2085 – 2089 .
  • Medvedev , A. E. , Veselovsky , A. V. , Shvedov , V. I. , Tikhonova , O. V. , Moskvitina , T. A. , Fedotova , O. A. , Axenova , L. N. , Kamyshanskaya , N. S. , Kirkel , A. Z. and Ivanov , A. S. 1998 . Inhibition of monoamine oxidase by pirlindole analogues: 3D QSAR and CoMFA analysis . J. Chem. Inf. Comput. Sci. , 38 : 1137 – 1144 .
  • Mashkovsky , M. D. 1997 . Drug Reference . Book. Toring, Harkov , 1 : 543 in Russian.
  • Hahn , M. 1995 . Receptor surface models. 1. Definition and construction . J. Med. Chem. , 38 : 2080 – 2090 .
  • Hahn , M. and Rogers , D. 1995 . Receptor surface models. 2. Application to quantitative structure-activity studies . J. Med. Chem. , 38 : 2091 – 2102 .
  • Zbinden , P. , Dobler , M. , Folkers , G. and Vedani , A. 1998 . PrGen: Pseudoreceptor modeling using receptor-mediated ligand alignment and pharmacophore equilibration . Quant. Struct.-Act. Relat. , 17 : 122 – 129 .
  • Kettmann , V. and Holtje , H.-D. 1998 . Mapping of the benzothiazepine binding site on the calcium channel . Quant. Struct.-Act. Relat. , 17 : 91 – 101 .
  • Medvedev , A. E. , Ivanov , A. S. , Kamyshanskaya , N. S. , Kirkel , A. Z. , Moskvitina , T. A. , Gorkin , V. Z. , Li , H. Y. and Marshakov , Yu. V. 1995 . Interaction of indole derivatives with monoamine oxidase A and B. Studies on the structure-inhibitory activity relationship . Biochem. Mol. Biol. Intern. , 36 : 113 – 122 .
  • Cesura , A. M. and Pletscher , A. 1992 . The new generation of monoamine oxidase inhibitors . Progr. Drug. Res. , 38 : 171 – 297 .

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