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Original Articles

QSAR and pharmacophore analysis on amides against drug-resistant S. aureusFootnote1

, , , , &
Pages 101-113 | Received 01 Sep 2007, Accepted 11 Nov 2007, Published online: 04 Dec 2010

References

  • Dalhoff , A . 1994 . Quinolone resistance in Pseudomonas aeruginosa and Staphylococcus aureus, Development during therapy and clinical significance . Infection , 22 : 111 – 121 .
  • Lee , V and Hecker , S . 1999 . Antibiotic resistance versus small molecules, the chemical evolution . J. Med. Chem. , 19 : 521 – 542 .
  • Livermore , D . 2000 . Antibiotic resistance in staphylococci . Int. J. Antimicrob. Agents , 16 : S3 – S10 .
  • Poole , K . 2001 . Multidrug resistance in gram-negative bacteria . Curr. Opin. Microbiol. , 4 : 500 – 508 .
  • Abbanat , D , Macielag , M and Bush , K . 2003 . Novel antibacterial agents for the treatment of serious Gram-positive infections . Expert Opin. Investig. Drugs , 12 : 379 – 399 .
  • Mrozik , H . 1969 . A new agent for the treatment of liver fluke infection (fascioliasis) . Experientia , 25 : 883
  • Japan Patent, 73, 37, 819, Chem. Abst. 81 (1974) 73387 (1973)
  • Braz Pedido PI N80 04, 641, Chem. Abst. 95 (1981) 61812z (1981)
  • White , GA . 1989 . Substituted 2-methylbenzanilides and structurally related carboxamides: Inhibition of complex II activity in mitochondria from a wild-type strain and a carboxin-resistant mutant strain of Ustilago maydis . Pest. Biochem. Physiol. , 34 : 255 – 276 .
  • Yalcin , I . 1997 . Synthesis and microbiological activity of some novel N-(2-Hydroxyl-5-substitutedphenyl)benzacetamides, phenoxyacetamides and thiophenoxyacetamides as the possible metabolites of antimicrobial active benzoxazoles . Il Farmaco , 52 : 685 – 689 .
  • Pradhan , KJ , Variyar , PS and Bandekar , JR . 1999 . Antimicrobial activity of novel phenolic compounds from green pepper (Piper nigrum L.) . Lebensm.-Wiss. U.-Technol. , 32 : 121 – 123 .
  • Aki Sener , E . 2000 . Synthesis and microbiological activity of some N-(o-hydroxyphenyl)benzamides and phenylacetamides as the possible metabolites of antimicrobial active benzoxazoles, Part II . Il Farmaco , 55 : 469 – 476 .
  • Aki-Sener , E . 2002 . Synthesis and microbiological activity of some N-(2-hydroxy-4-substitutedphenyl)benzamides, phenylacetamides and furamides as the possible metabolites of antimicrobial active benzoxazoles . Il Farmaco , 57 : 451 – 456 .
  • Yildiz-Oren , I . 2004 . Synthesis and microbiological activity of some substituted N-(2-hydroxy-4-nitrophenyl)benzamides and phenylacetamides as possible metabolites of antimicrobial active benzoxazoles . Turk J. Chem. , 28 : 441 – 449 .
  • Kobayashi , I . 2002 . In vitro anti-Helicobacter pylori activity of BAS-118, a new benzamide derivative . J. Antimicrob. Chemoth. , 50 : 129 – 132 .
  • Hansch , C and Leo , A . 1995 . Exploring QSAR: Fundamentals and applications in chemistry and biochemistry , Washington, DC : American Chemical Society .
  • Hansch , C and Fujita , T . 1964 . p–σ-π Analysis. A method for the correlation of biological activity and chemical structure . J. Am. Chem. Soc. , 86 : 1616 – 1626 .
  • Golender , VE and Vorpagel , ER . 1993 . 3D-QSAR in Drug design: Theory, methods, and applications , Edited by: Kubinyi , H . 137 The Netherlands : ESCOM Science Publishers .
  • Tekiner-Gulbas , B . 2007 . QSAR of genotoxic active benzazoles . SAR QSAR Environ. Res. , 18 : 251 – 263 .
  • Krovat , EM , Fruhwirth , KH and Langer , T . 2005 . Pharmacophore Identification, in silico screening, and virtual library design for inhibitors of the human factor Xa . J. Chem. Inf. Model. , 45 : 146 – 159 .
  • Ertan , T . 2007 . Synthesis and biological evaluation of new N-(2-hydroxy-4(or 5)-nitro/aminophenyl)benzamides and phenylacetamides as antimicrobial agents . Bioorg. & Med. Chem. , 15 : 2032 – 2044 .
  • 2004 . Accelrys Inc. Catalyst 4.9
  • Hansch , C , Leo , A and Hoekman , D . 1995 . Exploring QSAR: Hydrophobic, Electronic, and Steric Constants , Washington, DC : American Chemical Society .
  • 2004 . Accelrys Inc. Cerius2
  • The Regression Analysis Program BILIN . http://www.kubinyi.de/bilin-program.html
  • MINITAB Release 13.1 . http://www.minitab.com
  • Draper , N and Smith , H . 1966 . Applied Regression Analysis , New York : John Wiley & Sons .
  • Rawlings , JO . 1988 . Applied Regression Analysis , 186 – 189 . Pacific Grove, CA : Wadsworth & Brooks/Cole .
  • Wold , S . 1991 . Validation of QSAR's . Quant. Struct.-Act. Relat. , 10 : 191 – 193 .
  • Smellie , A , Kahn , SD and Teig , SL . 1995 . Analysis of conformational coverage. 1. Validation and estimation of coverage . J. Chem. Inf. Comput. Sci. , 35 : 285 – 294 .
  • Smellie , A , Kahn , SD and Teig , SL . 1995 . Analysis of conformational coverage. 2. Applications of conformational models . J. Chem. Inf. Comput. Sci. , 35 : 295 – 304 .
  • Smellie , A , Teig , SL and Towbin , P . 1994 . Poling: Promoting conformational variation . J. Comp. Chem. , 16 : 171 – 187 .
  • Greene , J . 1994 . Chemical function queries for 3D database search . J. Chem. Inf. Comput. Sci. , 34 : 1297 – 1308 .
  • Barnum , D . 1996 . Identification of common functional configurations among molecules . J. Chem. Inf. Comput. Sci. , 36 : 563 – 571 .
  • Kubinyi , H . 1993 . QSAR: Hansch Analysis and Related Approaches , Edited by: Mannhold , R , Krogsgaard-Larsen , P and Timmerman , H . 91 – 95 . Weinheim : Wiley-VCH .
  • Kubinyi , H . 1993 . QSAR: Hansch Analysis and Related Approaches , Edited by: Mannhold , R , Krogsgaard-Larsen , P and Timmerman , H . 59 Weinheim : Wiley-VCH .
  • Kubinyi , H . 1993 . QSAR: Hansch Analysis and Related Approaches , Edited by: Mannhold , R , Krogsgaard-Larsen , P and Timmerman , H . 63 Weinheim : Wiley-VCH .

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