362
Views
5
CrossRef citations to date
0
Altmetric
Original Articles

Using molecular docking to investigate the anti-breast cancer activity of low molecular weight compounds present on wild mushrooms

, &
Pages 315-328 | Received 02 Jul 2010, Accepted 02 Oct 2010, Published online: 18 May 2011

References

  • Wasser , SP . 2002 . Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides . Appl. Microbiol. Biotechnol. , 60 : 258 – 274 .
  • Zjawiony , JK . 2004 . Biologically active compounds from aphyllophorales (polypore) fungi . J. Nat. Prod. , 67 : 300 – 310 .
  • Zaidman , B , Yassin , M , Mahajana , J and Wasser , SP . 2005 . Medicinal mushrooms modulators of molecular targets as cancer therapeutics . Appl. Microbiol. Biotechnol. , 67 : 453 – 468 .
  • Mattila , P , Suonpaa , K and Piironen , V . 2000 . Functional properties of edible mushrooms . Nutrition , 16 : 694 – 696 .
  • Borchers , AT , Keen , CL and Gershwin , ME . 2004 . Mushrooms, tumors, and immunity: An update . Exp. Biol. Med. , 229 : 393 – 406 .
  • Zhang , M , Cui , SW , Cheung , PCK and Wang , Q . 2006 . Polysaccharides from mushrooms: A review on their isolation process, structural characteristics and antitumor activity . Trends Food Sci. Technol. , 18 : 4 – 19 .
  • Mizuno , T . 1993 . Food function and medicinal effect of mushroom fungi . Foods Food Ingred. J. , 158 : 55 – 70 .
  • Larone , DH . 2002 . Medically Important Fungi, A Guide to Identification , USA : American Society for Microbiology .
  • Zhang , M , Huang , J , Xie , X and Holman , CDJ . 2009 . Dietary intakes of mushrooms and green tea combine to reduce the risk of breast cancer in Chinese women . Int. J. Cancer , 124 : 1404 – 1408 .
  • Grube , BJ , Eng , ET , Kao , Y-C , Kwon , A and Chen , S . 2001 . White button mushroom phytochemicals inhibit aromatase activity and breast cancer cell proliferation . J. Nutr. , 131 : 3288 – 3293 .
  • Ferreira , ICFR , Barros , L and Abreu , RMV . 2009 . Antioxidants in wild mushrooms . Curr. Med. Chem. , 16 : 1543 – 1560 .
  • Barros , L , Ferreira , MJ , Queiros , B , Ferreira , ICFR and Baptista , P . 2007 . Total phenols, ascorbic acid, beta-carotene and lycopene in Portuguese wild edible mushrooms and their antioxidant activities . Food Chem. , 103 : 413 – 419 .
  • Barros , L , Correia , DM , Ferreira , ICFR , Baptista , P and Santos-Buelga , C . 2008 . Optimization of the determination of tocopherols in Agaricus sp. edible mushrooms by a normal phase liquid chromatographic method . Food Chem. , 110 : 1046 – 1050 .
  • Barros , L , Cruz , T , Baptista , P , Estevinho , LM and Ferreira , ICFR . 2008 . Wild and commercial mushrooms as source of nutrients and nutraceuticals . Food Chem. Toxicol. , 46 : 2742 – 2747 .
  • Barros , L , Falcao , S , Baptista , P , Freire , C , Vilas-Boas , M and Ferreira , ICFR . 2008 . Antioxidant activity of Agaricus sp mushrooms by chemical, biochemical and electrochemical assays . Food Chem. , 111 : 61 – 66 .
  • Barros , L , Ventuizini , BA , Baptista , P , Estevinho , LM and Ferreira , ICFR . 2008 . Chemical composition and biological properties of Portuguese wild mushrooms: A comprehensive study . J. Agric. Food Chem. , 56 : 3856 – 3862 .
  • Barros , L , Duenas , M , Ferreira , ICFR , Baptista , P and Santos-Buelga , C . 2009 . Phenolic acids determination by HPLC-DAD-ESI/MS in sixteen different Portuguese wild mushrooms species . Food Chem. Toxicol. , 47 : 1076 – 1079 .
  • Heleno , SA , Barros , L , Sousa , MJ , Martins , A and Ferreira , ICFR . 2009 . Tocopherols composition of Portuguese wild mushrooms with antioxidant capacity . Food Chem. , 119 : 1443 – 1450 .
  • Pasqualini , JR and Chetrite , GS . 2005 . Recent insight on the control of enzymes involved in estrogen formation and transformation in human breast cancer . J. Steroid Biochem. Mol. Biol. , 93 : 221 – 236 .
  • Pujadas , G , Vaque , M , Ardrevol , A , Blade , C , Salvado , MJ , Blay , M , Fernandez-Larrea , J and Arola , L . 2008 . Protein-ligand docking: A review of recent advances and future perspectives . Curr. Pharmaceut. Anal. , 1 : 1 – 19 .
  • Ghosh , S , Nie , AH , An , J and Huang , ZW . 2006 . Structure-based virtual screening of chemical libraries for drug discovery . Curr. Opin. Chem. Biol. , 10 : 194 – 202 .
  • Morris , GM , Goodsell , DS , Halliday , RS , Huey , R , Hart , WE , Belew , RK and Olson , AJ . 1998 . Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function . J. Comp. Chem. , 19 : 1639 – 1662 .
  • Sousa , SF , Fernandes , PA and Ramos , MJ . 2006 . Protein-ligand docking: Current status and future challenges . Proteins , 65 : 15 – 26 .
  • Li , CL , Xu , L , Wolan , DW , Wilson , IA and Olson , AJ . 2004 . Virtual screening of human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase against the NCI diversity set by use of AutoDock to identify novel nonfolate inhibitors . J. Med. Chem. , 47 : 6681 – 6690 .
  • Chen , K , Al Aowad , AF , Adelstein , SJ and Kassis , AI . 2007 . Molecular-docking-guided design, synthesis, and biologic evaluation of radioiodinated quinazolinone prodrugs . J. Med. Chem. , 50 : 663 – 673 .
  • Yan , KH , Wang , ZY , Liu , HL and Yu , HX . 2010 . Exploring the binding features of polybrominated diphenyl ethers as estrogen antagonists: Docking studies . SAR QSAR Environ. Res. , 21 : 351 – 367 .
  • Pedretti , A , Villa , L and Vistoli , G . 2004 . VEGA – An open platform to develop chemo-bio-informatics applications, using plug-in architecture and script programming . J. Comput. Aided Mol. Des. , 18 : 167 – 173 .
  • Sanner , MF . 2005 . A component-based software environment for visualizing large macromolecular assemblies . Structure , 13 : 447 – 462 .
  • Gasteiger , J and Marsili , M . 1980 . Iterative partial equalization of orbital electronegativity – a rapid access to atomic charges . Tetrahedron , 36 : 3219 – 3228 .
  • Abreu , RMV , Froufe , H , Queiroz , MJRP and Ferreira , ICFR . MOLA: a method for automation of parallel virtual screening using AutoDock 4/Vina in multiplatform non-dedicated computer clusters, J. Cheminformatics (2010), pp. 1–6
  • Numazawa , M , Oshibe , M , Yamaguchi , S and Tachibana , M . 1996 . Time-dependent inactivation of aromatase by 6 alkylandrosta-1,4-diene-3,17-diones, Effects of length and configuration of 6-alkyl group . J. Med. Chem. , 39 : 1033 – 1038 .
  • Ishida , H , Sato , N , Hosogi , J , Tanaka , H and Kuwarabara , T . 2008 . Inactivation of recombinant human steroid sulfatase by KW-2581 . J. Steroid Biochem. Mol. Biol. , 108 : 17 – 22 .
  • Mendoza-Hernandez , G , Calcagno , M , Sanchez-Nuncio , HR and Diaz-Zagoya , JC . 1984 . Dehydroepiandrosterone is a substrate for estradiol 17beta-dehydrogenase from human placenta . Biochem. Biophys. Res. Commun. , 119 : 83 – 87 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.