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Original

Protective Action of a Hydroalcoholic Extract of a Vinifera Grape Skin on Experimental Preeclampsia in Rats

, M.D., , Ph.D., , Ph.D. &
Pages 89-100 | Published online: 07 Jul 2009

REFERENCES

  • National High Blood Pressure Education Program Working Group: Report on high blood pressure in pregnancy. Am J Obstet Gynecol 1990; 163: 1689–1712
  • Rodie VA, Freeman DJ, Sattar N, Greer IA. Pre-eclampsia and cardiovascular disease: metabolic syndrome of pregnancy?. Atherosclerosis 2004; 175: 189–202
  • Roberts JM, Hubel CA. Oxidative stress in preeclampsia. Am J Obstet Gynecol 2004; 190: 1177–1178
  • Schobel HP, Fisher T, Heuszer K, Geiger H, Schmieder RE. Preeclampsia: a state of sympathetic overactivity. N Engl J Med 1996; 335: 1480–1485
  • Gant NF, Daley GL, Chand S, Whalley PJ. A study of angiotensin II pressor response throughout primigravid pregnancy. J Clin Invest 1973; 52: 2682–2689
  • Roberts JM, Taylor RN, Musci TJ, Rodgers GM, Hubel CA, McLaughlin MK. Preeclampsia: An endothelial cell disorder. Am J Obstet Gynecol 1990; 163: 1365–1366
  • Baylis C, Engels K. Adverse interactions between pregnancy and a new model of systemic hypertension produced by chronic blockade of endothelial derived relaxing factor (EDRF) in the rat. Clin Exp Hypertens Pregnancy 1992; B11: 117–129
  • Yallampalli C, Garfield RE. Inhibition of nitric oxide synthesis in rats during pregnancy produces signs similar to those of preeclampsia. Am J Obstet Gynecol 1993; 169: 1316–1320
  • Fickling SA, Willian D, Vallance P, Nussey SS, Whitley GS. Plasma concentration of endogenous inhibitor of nitric oxide synthesis in normal pregnancy and pre-eclampsia. Lancet 1993; 342: 242–243
  • Holden DP, Fickling SA, Whitley GS, Nussey SS. Plasma concentrations of asymmetric dimethylarginine, a natural inhibitor of nitric oxide synthase, in normal pregnancy and preeclampsia. Am J Obstet Gynecol 1998; 178: 551–556
  • Pettersson A, Hedner T, Milsom I. Increased circulating concentrations of assymmetric dimethyl arginine (ADMA), an endogenous inhibitor of nitric oxide dynthesis, in preeclampsia. Acta Obstet Gynecol Scand 1998; 77: 808–813
  • Soares de Moura R, Costa Vieira FS, Souza MAV, Kovary K, Guedes DC, Oliveira EPB, et al. Antihypertensive, vasodilator and antioxidant effects of vinifera grape-skin extract. J Pharm Pharmacol 2002; 54: 1515–1520
  • Frota Madeira SV, Castro Resende A, Ognibene DT, Sousa MAV, Soares de Moura. Mechanism of the endothelium-dependent vasodilator effect of na alcohol free extract obtained from a vinifera grape skin. Pharmacol Res 2005; 2: 321–327
  • Moura AS, Franco de Sa CC, Lopez da Costa C, Vicente LL, Guerreiro SM, Pinto AM. Association between nutrition and gender during lactation influencing glucose homeostasis and blood pressure of the adult offspring. Biol Neonate 2002; 82(4)263–270
  • Molnar M, Suto T, Tóth T, Hertelendy F. Prolonged blockade of nitric oxide synthesis in gravid rats produces sustained hypertension, proteinuria, thrombocytopenia, and intrauterine growth retardation. Am J Obstet Gynecol 1994; 170: 1458–1466
  • Umans JG, Liendheimer MD, Barron WM. Pressor effect of endothelium-derived relaxing factor inhibition in conscious virgin and gravid rats. Am J Physiol 1990; 259: F293–296
  • Magness RR, Rosenfeld CR. Calcium modulation of endothelium-derived prostacyclin production in ovide pregnancy. Endocrinology 1991; 132: 113–121
  • Walsh SW. Preeclampsia: an imbalance in placental prostacyclin and thromboxane production. Am J Obstet Gynecol 1985; 152: 335–340
  • Buhimschi IA, Saade GR, Chwalisz K, Garfield RE. The nitric oxide pathway in pre-eclampsia: patophysiological implications. Hum Reprod update 1998; 4: 25–42
  • Conrad KF, Joffe GM, Kruszyna H, Kruszyna R, Rochelle LG, Smith RP, et al. Identification of increased nitric oxide biosynthesis during pregnancy in rats. FASEB J 1993; 7: 566–571
  • Molnár M, Hertelendy F. Nω-Nitro-L-arginine, an inhibitor of nitric oxide synthesis, increases blood pressure in rats and reverses the pregnancy-induced refractoriness to vasopressor agents. Am J Obstet Gynecol 1992; 165: 1560–1967
  • Podjarny E, Benchetrit S, Katz B, Green J, Bernhein J. Effect of methyldopa on renal function in rats with L-name-induced hypertension in pregnancy. Nephron 2001; 88: 354–359
  • Wight E, Küng CF, Moreau P, Takase H, Lüscher TF. Chronic blockade of nitric oxide-synthase and andothelin receptors during pregnancy in the rat: effect of pregnancy outcome. J Soc Gynecol Invest 1998; 5: 132–139
  • Gairard A, Lopez-Miranda V, Pernot F, Beck JF, Coumaros G, Overloop BV, La Roche B, Koehl C, Christien MO. Effect of I1 imidazoline receptor agonist, moxonidine, in nitric oxide-deficient hypertension in pregnant rats. J Cardiovasc Pharmacol 2004; 43: 731–736
  • Walsh SC. Lipid peroxidation in pregnancy. Hypertension Preg 1994; 13: 1–25
  • Loverro G, Greco P, Capuano F, Carone D, Cormio G, Selvaggi L. Lipoperoxidation and antioxidant enzymes activity in pregnancy complicated with hypertension. Eur J Obstet Gynecol Reprod Biol. 1996; 27; 70(2)123–127
  • Edwards DL, Arora CP, Bui DT, Castro LC. Long-term nitric oxide blockade in the pregnant rat: effects on blood pressure and plasma levels of endothelin-1. Am J Obstet Gynecol 1996; 175: 484–488
  • Witlin AG, Gangula PRR, Thmpson ML, Yallamall C. Growth and fertility rates in the offspring of pregnant rats treated with L ω nitro L arginine methyl ester (L NAME), a nitric oxide inhibitor. Am J Obstet Gynecol 2002; 186(1)89–93
  • Tanir HM, Sener T, Inal M, Akyuz F, Uzuner K, Sivri E. Effect of quercetine and glutathione on the level of superoxide dismutase, catalase, malonyldialdehyde, blood pressure and neonatal outcome in a rat model of pre-eclampsia induced by NG-nitro-L-arginine-methyl ester. Eur J Obstet Gynecol 2005; 118: 190–195
  • Harrington K, Cooper D, Lees C, Hecher K, Campbell S. Doppler ultrasound of the uterine arteries: the importance of bilateral notching in the prediction of pre-eclampsia, placental abruption or delivery of a small-for-gestational-age baby. Ultrasound Obstet Gynecol 1996; 7: 182–188
  • Papaccio G, Esposito V, Latronico MV, Pisanti FA. Administration of a nitric oxide synthase inhibitor does not suppress low-dose streptozotocin-induced diabetes in mice. Int J Pancreatol 1995; 17: 63–68
  • Gonzales E, Rosello-Catafau J, Xaus J, Jawerbaum A, Novaro V, Gomes G, Gelpi Gimeno MA. Influence of nitric oxide synthase and kinin antagonists on metabolic parameters in chronic streptozotocin-induced diabetes mellitus. Prostaglandins 1997; 53: 321–336
  • Kaaja R, Laivuori H, Laakso M, Tikkanen MJ, Ylikorkala O. Evidence of a state of increased insulin resistance in preeclampsia. Metabolism 1999; 48: 892–896
  • Solomon CG, Seely EW. Brief review: Hypertension in pregnancy: a manifestation of the insulin resistance syndrome?. Hypertension 2001; 37: 232–239
  • Baron AD, Zhu J-S, Marshal S, Irsula O, Brechtel G, Keech C. Insulin resistance after hypertension induced by the nitric oxide synthesis inhibitor L-NMMA in rats. Am J Physiol 1995; 269: E709–715
  • Erlich Y, Rosenthal T. Chronic hypertension leads to hyperinsulinemia in Sprague-Dawley rats treated with nitric oxide synthase inhibitor. Am J Hypertens 1998; 11: 1129–1133
  • Roberts CK, Barnard RJ, Scheck SH, Balon TW. Exercise-stimulated glucose transport in skeletal muscle is nitric oxide dependent. Am J Physiol 1997; 273: E220–225
  • Balon TW, Nadler JL. Evidence that nitric oxide increases glucose transport in skeletal muscle. J Appl Physiol 1997; 82: 359–363
  • Napoli R, Cozzolino D, Guardasole V, Angelini V, Zarra E, Matarazzo M, et al. Red wine consumption improves insulin resistance but not endothelial function in type 2 diabetic patients. Metabolism Clinical and Experimental 2005; 54: 306–313
  • Al-Awwadi N, Araiz C, Bornet A, Delbosc S, Cristol JP, Linck N, et al. Extracts enriched in different polyphenolic families normalize increased cardiac NAPHD oxidase expression while having differential effects on insulin resistance, hypertension, and cardiac hypertrophy in high-fructose-fed rats. J Agric Food Chem 2005; 53(1)151–157

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