Açaí (Euterpe oleracea Mart) seed extract protects against maternal vascular dysfunction, hypertension, and fetal growth restriction in experimental preeclampsia

References

• Abalos E, Cuesta C, Grosso AL, et al. Global and regional estimates of preeclampsia and eclampsia: a systematic review. Eur J Obstet Gynecol Reprod Biol. 2013;170:1–7.
   PubMed Web of Science ®Google Scholar
• American College of Obstetricians and Gynecologists, Task Force on Hypertension in Pregnancy. Hypertension in pregnancy. Report of the American college of obstetricians and gynecologists’ task force on hypertension in pregnancy. Obstet Gynecol. 2013;122:1122–1131.
   PubMed Web of Science ®Google Scholar
• Phipps EA, Thadhani R, Benzing T, et al. Pre-eclampsia: pathogenesis, novel diagnostics and therapies. Nat Rev Nephrol. 2019;15:275–289.
   PubMed Web of Science ®Google Scholar
• Redman CW, Sargent IL. Latest advances in understanding preeclampsia. Science. 2005;308:1592–1594.
   PubMed Web of Science ®Google Scholar
• Granger JP, Alexander BT, Llinas MT, et al. Pathophysiology of hypertension during preeclampsia linking placental ischemia with endothelial dysfunction. Hypertens Dallas Tex. 1979;2001(38):718–722.
   Google Scholar
• Chesley LC, Talledo E, Bohler CS, et al. Vascular reactivity to angiotensin II and norepinephrine in pregnant women. Am J Obstet Gynecol. 1965;91:837–842.
   PubMed Web of Science ®Google Scholar
• Gant NF, Chand S, Whalley PJ, et al. The nature of pressor responsiveness to angiotensin II in human pregnancy. Obstet Gynecol. 1974;43:854.
   PubMed Web of Science ®Google Scholar
• Amaral TAS, Ognibene DT, Carvalho LCRM, et al. Differential responses of mesenteric arterial bed to vasoactive substances in L-NAME-induced preeclampsia: role of oxidative stress and endothelial dysfunction. Clin Exp Hypertens N Y N. 1993;2018(40):126–135.
   Google Scholar
• de Moura RS, Resende AC, Moura AS, et al. Protective action of a hydroalcoholic extract of a vinifera grape skin on experimental preeclampsia in rats. Hypertens Pregnancy. 2007;26:89–100.
   PubMed Web of Science ®Google Scholar
• Poniedziałek-Czajkowska E, Marciniak B, Kimber-Trojnar Z, et al. Nitric oxide in normal and preeclamptic pregnancy. Curr Pharm Biotechnol. 2011;12:743–749.
   PubMed Web of Science ®Google Scholar
• de Moura RS, Resende ÂC. Cardiovascular and metabolic effects of açaí, an Amazon plant. J Cardiovasc Pharmacol. 2016;68:19–26.
   PubMed Web of Science ®Google Scholar
• de Oliveira PRB, da Costa CA, de Bem GF, et al. Euterpe oleracea Mart.-derived polyphenols protect mice from diet-induced obesity and fatty liver by regulating hepatic lipogenesis and cholesterol excretion. PloS One. 2015;10:e0143721.
   PubMed Web of Science ®Google Scholar
• Rocha APM, Carvalho LCRM, Sousa MAV, et al. Endothelium-dependent vasodilator effect of Euterpe oleracea Mart. (açaí) extracts in mesenteric vascular bed of the rat. Vasc Pharmacol. 2007;46:97–104.
   PubMed Web of Science ®Google Scholar
• da Costa CA, de Oliveira PRB, de Bem GF, et al. Euterpe oleracea Mart.-derived polyphenols prevent endothelial dysfunction and vascular structural changes in renovascular hypertensive rats: role of oxidative stress. Naunyn Schmiedebergs Arch Pharmacol. 2012;385:1199–1209.
   PubMed Web of Science ®Google Scholar
• da Silva Cristino Cordeiro V, de Bem GF, da Costa CA, et al. Euterpe oleracea Mart. seed extract protects against renal injury in diabetic and spontaneously hypertensive rats: role of inflammation and oxidative stress. Eur J Nutr. 2018;57:817–832.
   PubMed Web of Science ®Google Scholar
• Rocha APM, Resende AC, Souza MAV, et al. antihypertensive effects and antioxidant action of a hydro-alcoholic extract obtained from fruits of Euterpe oleracea Mart. (acai). J Pharmacol Toxicol. 2008;3:435–448.
   Google Scholar
• de Moura RS, Ferreira TS, Lopes AA, et al. Effects of Euterpe oleracea Mart. (AÇAÍ) extract in acute lung inflammation induced by cigarette smoke in the mouse. Phytomed Int J Phytother Phytopharm. 2012;19:262–269.
   PubMed Web of Science ®Google Scholar
• Mcgregor DD. The effect of sympathetic nerve stimulation of vasoconstrictor responses in perfused mesenteric blood vessels of the rat. J Physiol. 1965;177:21–30.
   PubMed Web of Science ®Google Scholar
• Draper HH, Hadley M. Malondialdehyde determination as index of lipid peroxidation. Methods Enzymol. 1990;186:421–431.
   PubMed Web of Science ®Google Scholar
• Bannister JV, Calabrese L. Assays for superoxide dismutase. Methods Biochem Anal. 1987;32:279–312.
   PubMedGoogle Scholar
• Aebi H. Catalase in vitro. Methods Enzymol. 1984;105:121–126.
   PubMed Web of Science ®Google Scholar
• Flohé L, Günzler WA. Assays of glutathione peroxidase. Methods Enzymol. 1984;105:114–121.
   PubMed Web of Science ®Google Scholar
• Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72:248–254.
   PubMed Web of Science ®Google Scholar
• Sun J, Zhang X, Broderick M, et al. Measurement of nitric oxide production in biological systems by using griess reaction assay. Sensors. 2003;3:276–284.
   Web of Science ®Google Scholar
• McCarthy FP, Kingdom JC, Kenny LC, et al. Animal models of preeclampsia; uses and limitations. Placenta. 2011;32:413–419.
   PubMed Web of Science ®Google Scholar
• Brown C, McFarlane-Anderson N, Alexander-Lindo R, et al. The effects of S-nitrosoglutathione and S-nitroso-N-acetyl-D, L-penicillamine in a rat model of pre-eclampsia. J Nat Sci Biol Med. 2013;4:330–335.
   PubMedGoogle Scholar
• Valdes G, Kaufmann P, Corthorn J, et al. Vasodilator factors in the systemic and local adaptations to pregnancy. Reprod Biol Endocrinol. 2009;7:79.
   PubMed Web of Science ®Google Scholar
• Gillham JC, Kenny LC, Baker PN. An overview of endothelium-derived hyperpolarising factor (EDHF) in normal and compromised pregnancies. Eur J Obstet Gynecol Reprod Biol. 2003;109:2–7.
   PubMed Web of Science ®Google Scholar
• Hermsteiner M, Zoltan DR, Künzel W. The vasoconstrictor response of uterine and mesenteric resistance arteries is differentially altered in the course of pregnancy. Eur J Obstet Gynecol Reprod Biol. 2001;100:29–35.
   PubMed Web of Science ®Google Scholar
• Khalil RA, Crews JK, Novak J, et al. Enhanced vascular reactivity during inhibition of nitric oxide synthesis in pregnant rats. Hypertens Dallas Tex. 1979;1998(31):1065–1069.
   Google Scholar
• Stennett AK, Qiao X, Falone AE, et al. Increased vascular angiotensin type 2 receptor expression and NOS-mediated mechanisms of vascular relaxation in pregnant rats. Am J Physiol Heart Circ Physiol. 2009;296:H745–755.
   PubMed Web of Science ®Google Scholar
• Talebianpoor MS, Mirkhani H. The effect of tempol administration on the aortic contractile responses in rat preeclampsia model. ISRN Pharmacol. 2012;2012:187208.
   PubMedGoogle Scholar
• Takiuti NH, Carvalho MH, Kahhale S, et al. The effect of chronic nitric oxide inhibition on vascular reactivity and blood pressure in pregnant rats. Sao Paulo Med J Rev Paul Med. 1999;117:197–204.
   PubMedGoogle Scholar
• Crews JK, Herrington JN, Granger JP, et al. Decreased endothelium-dependent vascular relaxation during reduction of uterine perfusion pressure in pregnant rat. Hypertens Dallas Tex. 1979;2000(35):367–372.
   Google Scholar
• Anderson CM, Lopez F, Zhang H-Y, et al. Mesenteric vascular responsiveness in a rat model of pregnancy-induced hypertension. Exp Biol Med (Maywood, NJ). 2006;231:1398–1402.
   PubMed Web of Science ®Google Scholar
• Reid MB. Of balance and unbalance. J Appl Physiol Bethesda Md. 1985;2006(101):1011–1012.
   Google Scholar
• Barreiros ALBS, David JM, David JP. Estresse oxidativo: relação entre geração de espécies reativas e defesa do organismo. Quím Nova. 2006;29:113–123.
   Web of Science ®Google Scholar
• Dong X, Shi D. Simvastatin alleviates pathology in a rat model of preeclampsia involving ERK/MAPK pathway. Reprod Sci. 2017;24:1053–1061.
   PubMed Web of Science ®Google Scholar
• Kemse NG, Kale AA, Joshi SR. A combined supplementation of omega-3 fatty acids and micronutrients (folic acid, vitamin B12) reduces oxidative stress markers in a rat model of pregnancy induced hypertension. PloS One. 2014;9:e111902.
   PubMed Web of Science ®Google Scholar
• da Costa CA, Ognibene DT, Cordeiro VSC, et al. Effect of Euterpe oleracea Mart. seeds extract on chronic ischemic renal injury in renovascular hypertensive rats. J Med Food. 2017;20:1002–1010.
   PubMed Web of Science ®Google Scholar
• Williamson G, Clifford MN. Role of the small intestine, colon and microbiota in determining the metabolic fate of polyphenols. Biochem Pharmacol. 2017;139:24–39.
   PubMed Web of Science ®Google Scholar
• Márquez Campos E, Stehle P, Simon MC. Microbial metabolites of flavan-3-ols and their biological activity. Nutrients. 2019;11(10):2260.
   Web of Science ®Google Scholar
• Monagas M, Urpi-Sarda M, Sánchez-Patán F, et al. Insights into the metabolism and microbial biotransformation of dietaryflavan-3-ols and the bioactivity of their metabolites. Food Funct. 2010;1:233–253.
   PubMed Web of Science ®Google Scholar
• Yang K, Chan CB. Proposed mechanism of the effects of proanthocyanidins on glucose homeostasis. Nutr Rev. 2019;75(8):642–657.
   Web of Science ®Google Scholar
• Lei L, Yang Y, He H, et al. Flavan-3-ols consumption and cancer risk: A meta-analysis of epidemiologic studies. Oncotarget. 2016;7(45):73573–73592.
   PubMedGoogle Scholar
• Raman G, Shams-White M, Avendano EE, et al. Dietary intakes of flavan-3-ols and cardiovascular health: a field synopsis using evidence mapping of randomized trials and prospective cohort studies. Syst Rev. 2018;7(1):100.
   PubMedGoogle Scholar