Down-regulated placental miR-21 contributes to preeclampsia through targeting RASA1

References

• Duley L. The global impact of pre-eclampsia and eclampsia. Semin Perinatol. 2009 Jun;33(3):130–137.
   PubMed Web of Science ®Google Scholar
• von Dadelszen P, Magee LA, Roberts JM. Subclassification of preeclampsia. Hypertens Pregnancy. 2003;22(2):143–148.
   PubMed Web of Science ®Google Scholar
• Walker JJ. Pre-eclampsia. Lancet. 2000 Oct 7;356(9237):1260–1265.
   PubMed Web of Science ®Google Scholar
• Meekins JW, Pijnenborg R, Hanssens M, et al. A study of placental bed spiral arteries and trophoblast invasion in normal and severe pre-eclamptic pregnancies. Br J Obstet Gynaecol. 1994 Aug;101(8):669–674.
   PubMedGoogle Scholar
• Morales-Prieto DM, Ospina-Prieto S, Chaiwangyen W, et al. Pregnancy-associated miRNA-clusters. J Reprod Immunol. 2013 Mar;97(1):51–61.
   PubMed Web of Science ®Google Scholar
• Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell. 2009 Jan 23;136(2):215–233.
   PubMed Web of Science ®Google Scholar
• Javanmardi S, Aghamaali MR, Abolmaali SS, et al. miR-21, an oncogenic target miRNA for cancer therapy: Molecular mechanisms and recent advancements in chemo and radio-resistance. Curr Gene Ther. 2017;16(6):375–389.
   PubMed Web of Science ®Google Scholar
• Li S, Liang Z, Xu L, et al. MicroRNA-21: a ubiquitously expressed pro-survival factor in cancer and other diseases. Mol Cell Biochem. 2012 Jan;360(1–2):147–158.
   PubMed Web of Science ®Google Scholar
• Jazbutyte V, Thum T. MicroRNA-21: from cancer to cardiovascular disease. Curr Drug Targets. 2010 Aug;11(8):926–935.
   PubMed Web of Science ®Google Scholar
• Selcuklu SD, Donoghue MT, Spillane C. miR-21 as a key regulator of oncogenic processes. Biochem Soc Trans. 2009 Aug;37(Pt 4):918–925.
   PubMedGoogle Scholar
• Maccani MA, Padbury JF, Marsit CJ. miR-16 and miR-21 expression in the placenta is associated with fetal growth. PLoS One. 2011;6(6):e21210.
   PubMed Web of Science ®Google Scholar
• Choi SY, Yun J, Lee OJ, et al. MicroRNA expression profiles in placenta with severe preeclampsia using a PNA-based microarray. Placenta. 2013 Sep;34(9):799–804.
   PubMed Web of Science ®Google Scholar
• Boon LM, Mulliken JB, Vikkula M. RASA1: variable phenotype with capillary and arteriovenous malformations. Curr Opin Genet Dev. 2005 Jun;15(3):265–269.
   PubMed Web of Science ®Google Scholar
• Wittinghofer A. Signal transduction via Ras. Biol Chem. 1998 Aug-Sep;379(8–9):933–937.
   PubMed Web of Science ®Google Scholar
• Roberts JM, Pearson G, Cutler J, et al. Summary of the NHLBI working group on research on hypertension during pregnancy. Hypertension. 2003 Mar;41(3):437–445.
   PubMed Web of Science ®Google Scholar
• Dong K, Zhang MX, Liu Y, et al. Peroxisome proliferator-activated receptor alpha expression changes in human pregnant myometrium. Reprod Sci. 2013 Jun;20(6):654–660.
   PubMed Web of Science ®Google Scholar
• Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method. Methods. 2001 Dec;25(4):402–408.
   PubMed Web of Science ®Google Scholar
• Graham CH, Hawley TS, Hawley RG, et al. Establishment and characterization of first trimester human trophoblast cells with extended lifespan. Exp Cell Res. 1993 Jun;206(2):204–211.
   PubMed Web of Science ®Google Scholar
• Liu M, Wang Y, Lu H, et al. miR-518b enhances human trophoblast cell proliferation through targeting rap1b and activating ras-MAPK signal. Front Endocrinol (Lausanne). 2018;9:100.
   PubMed Web of Science ®Google Scholar
• Liu F, Wu K, Wu W, et al. miR203 contributes to preeclampsia via inhibition of VEGFA expression. Mol Med Rep. 2018 Apr;17(4):5627–5634.
   PubMed Web of Science ®Google Scholar
• Chi Z, Zhang M. Exploration of the regulation and control mechanisms of miR-145 in trophoblast cell proliferation and invasion. Exp Ther Med. 2018 Dec;16(6):5298–5304.
   PubMed Web of Science ®Google Scholar
• Knofler M. Critical growth factors and signalling pathways controlling human trophoblast invasion. Int J Dev Biol. 2010;54(2–3):269–280.
   PubMed Web of Science ®Google Scholar
• Moslehi R, Mills JL, Signore C, et al. Integrative transcriptome analysis reveals dysregulation of canonical cancer molecular pathways in placenta leading to preeclampsia. Sci Rep. 2013;3(1):2407.
   PubMedGoogle Scholar
• Lala PK, Lee BP, Xu G, et al. Human placental trophoblast as an in vitro model for tumor progression. Can J Physiol Pharmacol. 2002 Feb;80(2):142–149.
   PubMed Web of Science ®Google Scholar
• Zhou Y, Damsky CH, Fisher SJ. Preeclampsia is associated with failure of human cytotrophoblasts to mimic a vascular adhesion phenotype. One cause of defective endovascular invasion in this syndrome? J Clin Invest. 1997 May 1;99(9):2152–2164.
   PubMed Web of Science ®Google Scholar
• Taki K, Fukushima T, Ise R, et al. Microarray analysis of 6-mercaptopurine-induced-toxicity-related genes and microRNAs in the rat placenta. J Toxicol Sci. 2013 Feb;38(1):159–167.
   PubMed Web of Science ®Google Scholar
• Chaiwangyen W, Ospina-Prieto S, Photini SM, et al. Dissimilar microRNA-21 functions and targets in trophoblastic cell lines of different origin. Int J Biochem Cell Biol. 2015 Nov;68:187–196.
   PubMed Web of Science ®Google Scholar
• Chan JK, Blansit K, Kiet T, et al. The inhibition of miR-21 promotes apoptosis and chemosensitivity in ovarian cancer. Gynecol Oncol. 2014 Mar;132(3):739–744.
   PubMed Web of Science ®Google Scholar
• Liu ZL, Wang H, Liu J, et al. MicroRNA-21 (miR-21) expression promotes growth, metastasis, and chemo- or radioresistance in non-small cell lung cancer cells by targeting PTEN. Mol Cell Biochem. 2013 Jan;372(1–2):35–45.
   PubMed Web of Science ®Google Scholar
• Jin C, Zhao Y, Yu L, et al. MicroRNA-21 mediates the rapamycin-induced suppression of endothelial proliferation and migration. FEBS Lett. 2013 Feb 14;587(4):378–385.
   PubMed Web of Science ®Google Scholar
• Gong B, Liu WW, Nie WJ, et al. MiR-21/RASA1 axis affects malignancy of colon cancer cells via RAS pathways. World J Gastroenterol. 2015 Feb 7;21(5):1488–1497.
   PubMed Web of Science ®Google Scholar
• Sharma SB, Lin CC, Farrugia MK, et al. MicroRNAs 206 and 21 cooperate to promote RAS-extracellular signal-regulated kinase signaling by suppressing the translation of RASA1 and SPRED1. Mol Cell Biol. 2014 Nov 15;34(22):4143–4164.
   PubMed Web of Science ®Google Scholar
• Lapinski PE, Qiao Y, Chang CH, et al. A role for p120 RasGAP in thymocyte positive selection and survival of naive T cells. J Immunol. 2011 Jul 1;187(1):151–163.
   PubMed Web of Science ®Google Scholar
• Kern HB, Niemeyer BF, Parrish JK, et al. Control of MicroRNA-21 expression in colorectal cancer cells by oncogenic epidermal growth factor/Ras signaling and Ets transcription factors. DNA Cell Biol. 2012 Aug;31(8):1403–1411.
   PubMed Web of Science ®Google Scholar