Different dosage regimens of nifedipine, labetalol, and hydralazine for the treatment of severe hypertension during pregnancy: a network meta-analysis of randomized controlled trials

References

• Wertaschnigg D, Wang R, Reddy M, et al. Treatment of severe hypertension during pregnancy: we still do not know what the best option is. Hypertens Pregnancy. 2020;39(1):25–32.
   PubMed Web of Science ®Google Scholar
• Sahai R, Nidhi A, Ranjan R, et al. Comparative study of oral nifedipine versus intravenous labetalol in severe hypertension in pregnancy: a randomized controlled study. Int J Obstet Gynecol Res. 2020;7(1):75–80.
   Google Scholar
• Easterling T, Mundle S, Bracken H, et al. Oral antihypertensive regimens (nifedipine retard, labetalol, and methyldopa) for management of severe hypertension in pregnancy: an open-label, randomised controlled trial. Lancet. 2019;394(10203):1011–1021.
   PubMed Web of Science ®Google Scholar
• Webster K, Fishburn S, Maresh M, et al. Diagnosis and management of hypertension in pregnancy: summary of updated NICE guidance. Bmj. 2019;366:l5119.
   PubMed Web of Science ®Google Scholar
• WHO recommendations drug treatment for severe hypertension in pregnancy. 2018.
   Google Scholar
• Brown MA, Magee LA, Kenny LC, et al. International society for the study of hypertension in P. hypertensive disorders of pregnancy: ISSHP classification. Diagnosis, and Management Recommendations for International Practice. Hypertension. 2018;72(1):24–43.
   Google Scholar
• ACOG committee opinion no. 767 summary: emergent therapy for acute-onset, severe hypertension during pregnancy and the postpartum period. Obstet Gynecol. 2019;133(2):409–412.
   PubMed Web of Science ®Google Scholar
• Lopes RD, Hong H, Harskamp RE, et al. Safety and efficacy of antithrombotic strategies in patients with atrial fibrillation undergoing percutaneous coronary intervention: a network meta-analysis of randomized controlled trials. JAMA Cardiol. 2019;4(8):747–755.
   PubMed Web of Science ®Google Scholar
• Mavranezouli I, Megnin-Viggars O, Daly C, et al. Psychological and psychosocial treatments for children and young people with post-traumatic stress disorder: a network meta-analysis. J Child Psychol Psychiatry. 2020;6(1):18–29.
   Google Scholar
• Duley L, Meher S, Jones L. Drugs for treatment of very high blood pressure during pregnancy. Cochrane Database Syst Rev. 2013;31(7):CD001449.
   Google Scholar
• Holbrook B, Nirgudkar P, Mozurkewich E. 574: efficacy of hydralazine, labetalol, and nifedipine for the acute reduction of severe hypertension in pregnancy: a systematic review. Am J Obstet Gynecol. 2015;212(1):S286–S7.
   Web of Science ®Google Scholar
• Shi Q, Leng W, Yao Q, et al. Oral nifedipine versus intravenous labetalol for the treatment of severe hypertension in pregnancy. Int J Cardiol. 2015;178:162–164.
   PubMed Web of Science ®Google Scholar
• Shekhar S, Gupta N, Kirubakaran R, et al. Oral nifedipine versus intravenous labetalol for severe hypertension during pregnancy: a systematic review and meta-analysis. BJOG. 2016 Jan;123(1):40–47.
   PubMed Web of Science ®Google Scholar
• Sridharan K, Sequeira RP. Drugs for treating severe hypertension in pregnancy: a network meta-analysis and trial sequential analysis of randomized clinical trials. Br J Clin Pharmacol. 2018;84(9):1906–1916.
   PubMed Web of Science ®Google Scholar
• Alavifard S, Chase R, Janoudi G, et al. First-line antihypertensive treatment for severe hypertension in pregnancy: a systematic review and network meta-analysis. Pregnancy Hypertens. 2019;18179–187.
   PubMed Web of Science ®Google Scholar
• Wasim T, Agha S, Saeed K, et al. Oral Nifidepine versus IV labetalol in severe preeclampsia: a randomized control trial. Pak J Med Sci. 2020;36(6):1147–1152.
   PubMed Web of Science ®Google Scholar
• Sukhavasi DS, Sushma DM. A study on efficacy of intravenous labetalol versus oral nifedipine in control of acute hypertension in severe pre-eclampsia/eclampsia. Int J Clin Obstet Gynecol. 2020;4(4):198–204
   Google Scholar
• Kumari A, Rohatgi R, Singh A, et al. Comparative study of intravenous hydralazine and labetalol in severe hypertensive disorders of pregnancy. Int J Reprod Contracept Obstet Gynecol. 2020;9(2):675.
   Google Scholar
• Zulfeen M, Tatapudi R, Sowjanya R. IV labetalol and oral nifedipine in acute control of severe hypertension in pregnancy-A randomized controlled trial. Eur J Obstet Gynecol Reprod Biol. 2019;236:46–52.
   PubMed Web of Science ®Google Scholar
• Krishna K, Shailaja N, Bhat BS, et al. A randomized cross over trial of oral nifedipine and intravenous labetalol in pregnant women with severe pre-eclampsia and eclampsia. Int J Reprod Contracept Obstet Gynecol. 2019;8(3):921.
   Google Scholar
• Jamil S, Sengupta M, Saha C, et al. Oral nifedipine versus intravenous labetalol in hypertensive emergencies of pregnancy- A randomised trial. J Evol Med Dent Sci. 2019;8(48):3588–3592.
   Web of Science ®Google Scholar
• Alam A, Zakaria SMA. Oral nifedipine versus intravenous labetalol for acute blood pressure control in hypertensive emergencies of pregnancy: a randomized controlled trial. Int J Reprod Contracept Obstet Gynecol. 2019;8(5):1921.
   Google Scholar
• Verma M, Gupta S, Bhagat BR, et al. Comparison of intravenous hydralazine and intravenous labetalol in the management of severe hypertensive disorders of pregnancy: a tertiary care centre study. Int J Reprod Contracept Obstet Gynecol. 2018;7(6):2251.
   Google Scholar
• Thalamati S, Bandaru S, Bhumireddy D. Assessment of safety and efficacy of oral nifedipine and intravenous labetalol in management of increased blood pressure in severe preeclampsia. Int J Reprod Contracept Obstet Gynecol. 2018;7(7):2645.
   Google Scholar
• MN SR, Qamar S, Zafar O. Acute management of hypertensive emergencies in pregnancy: oral nifedipine versus intravenous labetalol. Pak Armed Forces Med J. 2018;68(6):1664–1667.
   Google Scholar
• Patel P, Koli D, Maitra N, et al. Comparison of efficacy and safety of intravenous labetalol versus hydralazine for management of severe hypertension in pregnancy. J Obstet Gynaecol India. 2018;68(5):376–381.
   PubMed Web of Science ®Google Scholar
• Dey R, Mukhopadhyay A, Chandra Biswas S, et al. Intravenous labetalol versus oral nifedipine for acute blood pressure control in severe pregnancy-induced hypertension- a randomised trial. J Evol Med Dent Sci. 2017;6(92):6578–6582.
   Web of Science ®Google Scholar
• Shi DD, Yang FZ, Zhou L, et al. Oral nifedipine vs. intravenous labetalol for treatment of pregnancy-induced severe pre-eclampsia. J Clin Pharm Ther. 2016;41(6):657–661.
   PubMed Web of Science ®Google Scholar
• YS SS, Abbas G. Comparison of oral nifedipine with intravenous hydralazine for acute hypertensive emergencies of pregnancy. J Postgrad Med Inst. 2016. 30(4).
   Google Scholar
• Kumari VR, Saraswathi K, Srilaxmi A. Oral nifedipine versus intravenous labetalol for control of blood pressure in severe preeclampsia. J. Evolution Med.Dent. Sci. 2016;5(20):994–997.
   Google Scholar
• JR DBS. Oral nifedipine versus intravenous labetalol in hypertensive emergencies of pregnancy: a randomised trial. Res J Pharm Biol Chem Sci. 2015;6:1673–1681.
   Google Scholar
• BS DS, Das P, Mahapatra B. Comparative study of intravenous labetalol and oral nifedipine for control of blood pressure in severe preeclampsia. J Dent Med Sci. 2015;14:22–27.
   Google Scholar
• Shekhar S, Sharma C, Thakur S, et al. Oral nifedipine or intravenous labetalol for hypertensive emergency in pregnancy: a randomized controlled trial. Obstet Gynecol. 2013;122(5):1057–1063.
   PubMed Web of Science ®Google Scholar
• Raheem IA, Saaid R, Omar SZ, et al. Oral nifedipine versus intravenous labetalol for acute blood pressure control in hypertensive emergencies of pregnancy: a randomised trial. BJOG. 2012;119(1):78–85.
   PubMed Web of Science ®Google Scholar
• Dhali B, Bhattacharya S, Ganguly R, et al. A randomized trial of intravenous labetalol and oral nifedipine in severe pregnancy induced hypertension. Int J Reprod Contracept Obstet Gynecol. 2012;42–46. https://doi.org/10.5455/2320-1770.ijrcog001912
   Google Scholar