References
- Patel KP, Li Y-F, Hirooka Y. Role of nitric oxide in central sympathetic outflow. Exp Biol Med 2001; 226: 814–824
- Zanzinger J. Role of nitric oxide in the neural control of cardiovascular function. Cardiovasc Res 1999; 43: 639–649
- Guyenet PG. The sympathetic control of blood pressure. Nat Rev Neurosci 2006; 7: 335–346
- Dampney RAL. Functional organization of central pathways regulating the cardiovascular system. Physiol Rev 1994; 74: 323–364
- Chou T-C, Yen M-H, Li C-Y, Ding Y-A. Alteration of nitric oxide synthase expression with aging and hypertension in rats. Hypertension 1998; 31: 643–648
- Yamakawa H, Jerova M, Ando H, Saavedra JM. Normalization of endothelial and inducible nitric oxide synthase expression in brain microvessels of spontaneously hypertensive rats by angiotensin II AT1 receptor inhibition. J Cereb Blood Flow Metab 2003; 23: 371–380
- Sesso HD, Buring JE, Rifai N, Blake GJ, Gaziano JM, Ridker PM. C-reactive protein and the risk of developing hypertension. JAMA 2003; 290: 2945–2951
- Pedrinelli R, Dell'Omo G, Di Bello V, Pellegrini G, Pucci L, Del Prato S, Penno G. Low-grade inflammation and microalbuminuria in hypertension. Arterioscler Thromb Vasc Biol 2004; 24: 2414–2419
- Salles GF, Fiszman R, Cardoso CRL, Muxfeldt ES. Relation of left ventricular hypertrophy with systemic inflammation and endothelial damage in resistant hypertension. Hypertension 2007; 50: 723–728
- Kimura Y, Hirooka Y, Sagara Y, Ito K, Kishi T, Shimokawa H, Takeshita A, Sunagawa K. Overexpression of inducible nitric oxide synthase in rostral ventrolateral medulla causes hypertension and sympathoexcitation via an increase in oxidative stress. Circ Res 2005; 96: 252–260
- Hirooka Y, Shigematsu H, Kishi T, Kimua Y, Ueta Y, Takeshita A. Reduced nitric oxide synthase in the brainstem contributes to enhanced sympathetic drive in rats with heart failure. J Cardiovasc Pharmacol 2003; 42(suppl. 1)S111–S115
- Kishi T, Hirooka Y, Ito K, Sakai K, Shimokawa H, Takeshita A. Cardiovascular effects of overexpression of endothelial nitric oxide synthase in the rostral ventrolateral medulla in stroke-prone spontaneously hypertensive rats. Hypertension 2002; 39: 264–268
- Kishi T, Hirooka Y, Mukai Y, Shimokawa H, Takeshita A. Atorvastatin causes depressor and sympatho-inhibitory effects with upregulation of nitric synthases in stroke-prone spontaneously hypertensive rats. J Hypertens 2003; 21: 379–386
- Kishi T, Hirooka Y, Kimura Y, Ito K, Shimokawa H, Takeshita A. Increased reactive oxygen species in rostral ventrolateral medulla contribute to neural mechanisms of hypertension in stroke-prone spontaneously hypertensive rats. Circulation 2004; 109: 2357–2362
- Chan SHH, Wang L-L, Wang S-H, Chan JYH. Differential cardiovascular responses to blockade of nNOS or iNOS in rostral ventrolateral medulla of the rat. Br J Pharmacol 2001; 133: 606–614
- Chan JYH, Wang L-L, Wu KLH, Chan SHH. Reduced functional expression and molecular synthesis of inducible nitric oxide synthase in rostral ventrolateral medulla of spontaneously hypertensive rats. Circulation 2001; 104: 1676–1681
- Tai M-H, Wang L-L, Wu KLH, Chan JYH. Increased superoxide anion in rostral ventrolateral medulla contributes to hypertension in spontaneously hypertensive rats via interactions with nitric oxide. Free Rad Biol Med 2005; 38: 450–462
- Kimura Y, Hirooka Y, Sagara Y, Sunagawa K. Long-acting calcium channel blocker, azelnidipine, increases endothelial nitric oxide synthase in the brain and inhibits sympathetic nerve activity. Clin Exp Hypertens 2007; 29: 13–21
- Hirooka Y, Kimura Y, Nozoe M, Sagara Y, Ito K, Sunagawa K. Amlodipine-induced reduction of oxidative stress in the brain is associated with sympatho-inhibitory effects in stroke-prone spontaneously hypertensive rats. Hypertens Res 2006; 29: 49–56
- Sagara Y, Ito L, Kimura Y, Hirooka Y. Telmisartan reduces oxidative stress in the brain with sympathoinhibitory effects in stroke-prone spontaneously hypertensive rats. Circulation 2004; 110(suppl. III)265, abstract