References
- Alashi A, Smedira NG, Popovic ZB, Fava A, Thamilarasan M, Kapadia SR, Wierup P, Lever HM, Desai MY. Characteristics and outcomes of elderly patients with hypertrophic cardiomyopathy. J Am Heart Assoc. 2021;e018527. doi:https://doi.org/10.116/JAHA.120.018527.
- Mouton AJ, Li X, Hall ME, Hall JE.Obesity, hypertension, and cardiac dysfunction: novel roles of immunometabolism in macrophage activation and inflammation. Circ Res. 2020;126(6):789–806.doi:https://doi.org/10.1161/CIRCRESAHA.119.312321.
- Caillon A, Paradis P, Schiffrin EL.Role of immune cells in hypertension. Br J Pharmacol. 2019;176(12):1818–28.doi:https://doi.org/10.1111/bph.14427.
- Shah KH, Shi P, Giani JF, Janjulia T, Bernstein EA, Li Y, Zhao T, Harrison DG, Bernstein KE, Shen XZ, et al. Myeloid suppressor cells accumulate and regulate blood pressure in hypertension. Circ Res. 2015;117(10):858–69.doi:https://doi.org/10.1161/CIRCRESAHA.115.306539.
- Kain D, Amit U, Yagil C, Landa N, Naftali-Shani N, Molotski N, Aviv V, Feinberg MS, Goitein O, Kushnir T. Macrophages dictate the progression and manifestation of hypertensive heart disease. Int J Cardiol. 2016;203:381–95. doi:https://doi.org/10.1016/j.ijcard.2015.10.126.
- Wenzel U, Turner JE, Krebs C, Kurts C, Harrison DG, Ehmke H.Immune mechanisms in arterial hypertension. J Am Soc Nephrol. 2016;27(3):677–86.doi:https://doi.org/10.1681/ASN.2015050562.
- XuQ, ChoksiS, Qu J, Jang J, ChoeM, BanfiB, EngelhardtJF, LiuZG. NADPH oxidases are essential for macrophage differentiation. J Biol Chem. 2016;16:291(38):20030-41.doi:https://doi.org/10.1074/jbc.M116.731216.
- ThangLV, Demel SL, Crawford R, Kaminski NE, Swain GM,Rooijen NV, Galligan JJ. Macrophage depletion lowers blood pressure and restores sympathetic nerve α2-adrenergic receptor function in mesenteric arteries of DOCA-salt hypertensive rats. Am J Physiol Heart Circ Physiol. 2015;309(7):H1186–97.doi:https://doi.org/10.1152/ajpheart.00283.2015.
- Hulsmans M, Sam F, Nahrendorf M. Monocyte and macrophage contributions to cardiac remodeling. J Mol Cell Cardiol. 2016;93:149–55.doi:https://doi.org/10.1016/j.yjmcc.2015.11.015.
- Zhou MS, Schulman IH, Raij L.Role of angiotensin II and oxidative stress in vascular insulin resistance linked to hypertension. Am J Physiol Heart Circ Physiol. 2009;296(3):H833–9.doi:https://doi.org/10.1152/ajpheart.01096.2008.
- Wade B, Petrova G, Mattson DL.Role of immune factors in angiotensin II-induced hypertension and renal damage in Dahl salt-sensitive rats. Am J Physiol Regul Integr Comp Physiol. 2018;314(3):R323–R33.doi:https://doi.org/10.1152/ajpregu.00044.2017.
- Abdel Ghafar MT. An overview of the classical and tissue-derived renin-angiotensin-aldosterone system and its genetic polymorphisms in essential hypertension. Steroids. 2020;163:108701.doi:https://doi.org/10.1016/j.steroids.2020.108701.
- Jordan MB, van Rooijen N, Izui S, Kappler J, Marrack P.Liposomal clodronate as a novel agent for treating autoimmune hemolytic anemia in a mouse model. Blood. 2003;101(2):594–601.doi:https://doi.org/10.1182/blood-2001-11-0061.
- Huang L, Wang A, Hao Y, Li W, Liu C, Yang Z, Zheng F, Zhou MS. Macrophage depletion lowered blood pressure and attenuated hypertensive renal injury and fibrosis. Front Physiol. 2018;9:473. doi:https://doi.org/10.3389/fphys.2018.00473. eCollection 2018.
- Claassen I, Van Rooijen N, Claassen E.A new method for removal of mononuclear phagocytes from heterogeneous cell populations in vitro, using the liposome-mediated macrophage ‘suicide’ technique. J Immunol Methods. 1990;134(2):153–61.doi:https://doi.org/10.1016/0022-1759(90)90376-7.
- Zhou MS, Jaimes EA, Raij L.Vascular but not cardiac remodeling is associated with superoxide production in angiotensin II hypertension. J Hypertens. 2005;23(9):1737–43.doi:https://doi.org/10.1097/01.hjh.0000179513.71018.09.
- Zhou MS, Adam AG, Jaimes EA, Raij L.In salt-sensitive hypertension, increased superoxide production is linked to functional upregulation of angiotensin II. Hypertension. 2003;42(5):945–51.doi:https://doi.org/10.1161/01.HYP.0000094220.06020.C8.
- Pellieux C, Sauthier T, Aubert JF, Brunner HR, Pedrazzini T.Angiotensin II-induced cardiac hypertrophy is associated with different mitogen-activated protein kinase activation in normotensive and hypertensive mice. J Hypertens. 2000;18(9):1307–17.doi:https://doi.org/10.1097/00004872-200018090-00017.
- Wenzel P, Knorr M, Kossmann S, Stratmann J, Hausding M, Schuhmacher S, Karbach SH, Schwenk M, Yogev N, Schulz E, et al. Lysozyme M-positive monocytes mediate angiotensin II-induced arterial hypertension and vascular dysfunction. Circulation.2011;124(12):1370–81.doi:https://doi.org/10.1161/CIRCULATIONAHA.111.034470.
- Small HY, Migliarino S, Czesnikiewicz-Guzik M, Guzik TJ. Hypertension: focus on autoimmunity and oxidative stress. Free Radic Biol Med. 2018;125:104–15.
- Lafuse WP, Wozniak DJ, Rajaram MVS. Role of cardiac macrophages on cardiac inflammation, fibrosis and tissue repair. Cells. 2020;10:1.doi:https://doi.org/10.3390/cells10010051.
- Yang D, Liu HQ, Liu FY, Tang N, Guo Z, Ma SQ, An P, Wang M-Y, Wu H-M, Yang Z, et al. Critical roles of macrophages in pressure overload-induced cardiac remodeling. J Mol Med. 2021;99(1):33–46.doi:https://doi.org/10.1007/s00109-020-02002-w.
- Hu B, Song JT, Ji XF, Liu ZQ, Cong ML, Liu DX. Sodium ferulate protects against angiotensin II-induced cardiac hypertrophy in mice by regulating the MAPK/ERK and JNK pathways. Biomed Res Int. 2017;2017:3754942.doi:https://doi.org/10.1155/2017/3754942.
- Faraco G, Sugiyama Y, Lane D, Garcia-Bonilla L, Chang H, Santisteban MM, Racchumi G, Murphy M, Van Rooijen N, Anrather J, et al. Perivascular macrophages mediate the neurovascular and cognitive dysfunction associated with hypertension. J Clin Invest. 2016;126(12):4674–89.doi:https://doi.org/10.1172/JCI86950.
- Sriramula S, Francis J.Tumor necrosis factor - alpha is essential for angiotensin II-induced ventricular remodeling: role for oxidative stress. PLoS One.2015;10(9):e0138372.doi:https://doi.org/10.1371/journal.pone.0138372.
- Cai R, Hao Y, Liu YY, Huang L, Yao Y, Zhou MS. Tumor necrosis factor alpha deficiency improves endothelial function and cardiovascular injury in deoxycorticosterone acetate/salt-hypertensive mice. Biomed Res Int. 2020;2020:3921074.doi:https://doi.org/10.1155/2020/3921074.
- Gallo S, Vitacolonna A, Bonzano A, Comoglio P, Erk: CT, Key A. Player in the Pathophysiology of Cardiac Hypertrophy. Int J Mol Sci. 2019;20:9.doi:https://doi.org/10.3390/ijms20092164.
- Meijles DN, Cull JJ, Markou T, Cooper STE, Haines ZHR, Fuller SJ, O’Gara P, Sheppard MN, Harding SE, Sugden PH, et al. Redox regulation of cardiac ASK1 (Apoptosis Signal-Regulating Kinase 1) controls p38-MAPK (Mitogen-Activated Protein Kinase) and orchestrates cardiac remodeling to hypertension. Hypertension. 2020;76(4):1208–18.doi:https://doi.org/10.1161/HYPERTENSIONAHA.119.14556.
- Forrester SJ, Elliott KJ, Kawai T, Obama T, Boyer MJ, Preston KJ, Yan Z, Eguchi S, Rizzo V. Caveolin-1 deletion prevents hypertensive vascular remodeling induced by Angiotensin II. Hypertension. 2017;69(1):79–86.doi:https://doi.org/10.1161/HYPERTENSIONAHA.116.08278.
- Ding J, Tang Q, Luo B, Zhang L, Lin L, Han L, Hao M, Li M, Yu L, Li M, et al. Klotho inhibits angiotensin II-induced cardiac hypertrophy, fibrosis, and dysfunction in mice through suppression of transforming growth factor-beta1 signaling pathway. Eur J Pharmacol. 2019;859:172549.
- Han J, Ye S, Zou C, Chen T, Wang J, Li J, Jiang L, Xu J, Huang W, Wang Y, et al. Angiotensin II causes biphasic STAT3 activation through TLR4 to initiate cardiac remodeling. Hypertension. 2018;72(6):1301–11.doi:https://doi.org/10.1161/HYPERTENSIONAHA.118.11860.
- Ainscough JFX, Drinkhill MJ, Sedo A, Turner NA, Brooke DA, Balmforth J, Ball SG. Angiotensin II type-1 receptor activation in the adult heart causes blood pressure-independent hypertrophy and cardiac dysfunction. Cardiovasc Res. 2009;81(3):592–600.doi:https://doi.org/10.1093/cvr/cvn230.
- Kobayahsi A, Ishikawa K, Matsumoto H, Kimura S, Kamiyama Y, Muruyama Y.Synthegetic antioxidant and vasodilatory action of carbon monoxide in angiotensin II-induced cardiac hypertrophy. Hypertension.2007;50(6):1040–48.doi:https://doi.org/10.1161/HYPERTENSIONAHA.107.097006.