Techniques for the assessment of carcinogenic risk due to drinking water contaminants

References

• Anderson , E. L. and the Carcinogen Assessment Group of the U.S. Environmental Protection Agency . 1983 . Quantitative approaches in use to assess cancer risk . Risk Anal. , 3 : 277
   Google Scholar
• Cothern , C. R. and Van Ryzin , J. 1985 . “ Risk assessment for the regulation of carcinogens in the environment ” . In Hazard Assessment of Chemicals: Current Developments , Edited by: Saxena , J. Vol. 4 , 179 New York : Academic Press .
   Google Scholar
• Baughman , G. and Lassiter , R. 1978 . Prediction of Environmental Pollutant Concentration , Philadelphia, Pa. : American Society for Testing and Materials . ASTM STP 657
   Google Scholar
• 1980 . “ Quantitative risk assessment ” . In Proposed System for Food Safety Assessment , 137 Washington, D.C. : Food and Safety Council .
   Google Scholar
• Mackay , D. , Paterson , S. and Joy , M. 1983 . “ Application of fugacity models to the estimation of chemical distribution and persistence in the environment ” . In Fate of Chemicals in the Environment , ACS Symposium Series Edited by: Swann , R. L. and Eschenroeder , A. 175 Washington, D.C. : American Chemical Society .
   Google Scholar
• Onishi , Y. , Whelan , G. and Skaggs , R. L. 1982 . Development of a Multimedia Radionuclide Exposure Assessment Methodology for Low‐Level Waste Management , Athens, Ga. : Office of Research and Development, U.S. Environmental Protection Agency .
   Google Scholar
• Schnorr , J. L. , Rao , N. , Cartright , K. J. and Rutz‐Calzada , P. 1981 . Verification of a Toxic Organic Substance Transport and Bioaccumulation Model , Final Report Athens, Ga. : Office of Research and Development, U.S. Environmental Protection Agency .
   Google Scholar
• Scow , K. , Weschler , A. , Wood , M. and Callahan , M. 1979 . Identification and Evaluation of Waterborne Routes of Exposure from Other Than Food and Drinking Water , Report EPA‐440/4–79–016 Washington, D.C. : U.S. Environmental Protection Agency .
   Google Scholar
• Neely , W. B. and Blau , G. E. , eds. 1985 . Environmental Exposure from Chemicals , Vol. 2 , Boca Raton, Fla. : CRC Press .
   Google Scholar
• January 1985 . Risk Assessment and Risk Assessment Methods: The State of the Art , January , Washington, D.C. : Prepared for the Office of Management and Budget by the Division of Policy Research and Analysis, National Science Foundation . NSE/PRA‐84016
   Google Scholar
• Parsons , F. and Lage , G. B. 1985 . Chloronated organics in simulated groundwater environments . J. Am. Waterworks Assoc. , 77 : 52
   Web of Science ®Google Scholar
• Parsons , F. , Wood , P. R. and DeMarco , J. 1984 . Transformations of tetrachloroethane and trichloroethane . Microcosms and Groundwater , 76 : 56
   Google Scholar
• Weibull , W. 1951 . A statistical distribution function of wide applicability . J. Appl. Mech. , 18 : 293
   Web of Science ®Google Scholar
• Linaweaver , F. P. Jr. October 1963 . Report on Phase One, Residential Water House Research Project, reported in a study of flow reduction and treatment of wastewater from households , October , The Johns Hopkins University, Department of Sanitary Engineering .
   Google Scholar
• Bailer , J. R. 1969 . General Dynamics Report for the Federal Water Quality Administration
   Google Scholar
• Cothern , C. R. , Coniglio , W. A. and Marcus , W. L. 1984 . Techniques for the Assessment of the Carcinogenic Risk to the U.S. Population Due to Exposure from Selected Volatile Organic Compounds from Drinking Water Via the Ingestion, Inhalation and Dermal Routes, U.S. Environmental Protection Agency , Springfield, Va. : National Technical Information Service . EPA 570/ 9–85–001, NTIS Assession No. PB84 213941
   Google Scholar
• Canadian Environmental Health Directorate . 1981 . Tap Water Consumption in Canada , Ministry of National Health and Welfare . Publication 82EHD80
   Google Scholar
• U.S. Environmental Protection Agency . 1976 . National Interim Primary Drinking Water Regulations , Washington, D.C. : Office of Drinking Water . EPA‐570/ 9–76–003, WH‐550
   Google Scholar
• Hess , C. T. , Weiffenbach , C. V. and Norton , S. A. 1982 . Variations of airborne and waterborne Rn‐222 in houses in Maine . Environ. Int. , 8 : 59
   Google Scholar
• Kalos , H. and Asikainen , M. 1980 . Internal radiation doses from radioactivity in drinking water in Finland . Health Phys. , 39 : 108
   PubMed Web of Science ®Google Scholar
• 1982 . “ United Nations Scientific Committee on the Effects of Atomic Radiation — UNSCEAR ” . In Sources and Effects of Ionizing Radiation , New York : United Nations .
   Google Scholar
• Andelman , J. B. 1984 . Non‐Ingestion Exposure to Chemicals in Potable Water , Working Paper No. 84–03 Pittsburgh, Pa. : Center for Environmental Epidemiology, Graduate School of Public Health, University of Pittsburgh .
   Google Scholar
• Brown , H. S. , Bishop , D. R. and Rowan , C. A. 1984 . The role of skin adsorption as a route of exposure for volatile organic compounds (VOCs) in drinking water . Am. J. Public Health , 74 : 479
   PubMed Web of Science ®Google Scholar
• Maibach , H. I. and Feldman , R. J. 1969 . Effect of applied concentration on percutaneous adsorption in man . J. Invest. Dermatol. , 52 : 382
   Web of Science ®Google Scholar
• Maiback , H. I. and Anjo , D. M. 1981 . Pecutaneous penetration of benzene contained in solvents used in the rubber industry . Arch. Environ. Health , 36 : 256
   PubMedGoogle Scholar
• Wester , R. C. and Maibach , H. I. 1975 . Percutaneous adsorption in the rhesus monkey compared to man . Toxicol. Appl. Pharmacol. , 32 : 394
   PubMed Web of Science ®Google Scholar
• Wester , R. C. and Maibach , H. I. 1976 . Relationship of topical dose percutaneous absorption in rhesus monkey and man . J. Invest. Dermatol. , 67 : 518
   PubMed Web of Science ®Google Scholar
• Wester , R. C. and Maibach , H. I. 1977 . “ Percutaneous absorption in man and animals: a perspective ” . In Cutaneous Toxicology , Edited by: Drill , V. and Lazar , P. 111 New York : Academic Press .
   Google Scholar
• Wester , R. C. , Noonan , P. K. and Maibach , H. I. 1979 . Recent advances in percutaneous absorption using the rhesus monkey model . J. Soc. Cosmet. Chem. , 30 : 297
   Web of Science ®Google Scholar
• Wester , R. C. and Noonan , P. K. 1980 . Relevance of animal models for percutaneous absorption . Int. J. Pharmacol. , 7 : 99
   Web of Science ®Google Scholar
• Wester , R. C. and Maibach , H. I. 1983 . Cutaneous pharmacokinetic: 10 steps to percutaneous absorption . Drug Metab. Rev. , 14 : 169
   PubMed Web of Science ®Google Scholar
• Evans , R. D. 1974 . Radium in man . Health Phys. , 27 : 497
   Web of Science ®Google Scholar
• 1980 . International Commission on Radiological Protection , Report 30 Fairview Park, Elmsford, N.Y. : Pergamon Press .
   Google Scholar
• National Academy of Sciences . 1980 . The Effects on Populations of Exposure to Low Levels of Ionizing Radiation , (BEIR III Report) Washington, D.C. : National Academy Press .
   Google Scholar
• 1986 . Draft Criteria Document for Radon in Drinking Water , Office of Drinking Water (WH‐550) Washington, D.C. : U.S. Environmental Protection Agency .
   Google Scholar
• 1986 . Draft Criteria Document for Uranium in Drinking Water , Office of Drinking Water (WH‐550) Washington, D.C. : U.S. Environmental Protection Agency .
   Google Scholar
• 1986 . Draft Criteria Document for Radium in Drinking Water , Office of Drinking Water (WH‐550) Washington, D.C. : U.S. Environmental Protection Agency .
   Google Scholar
• 1986 . Draft Criteria Document for Man‐Made Radionuclides in Drinking Water , Office of Drinking Water (WH‐550) Washington, D.C. : U.S. Environmental Protection Agency .
   Google Scholar
• Cothern , C. R. , Lappenbusch , W. L. and Michel , J. 1986 . Drinking water contribution to natural background radiation . Health Phys. , 50 : 33
   PubMed Web of Science ®Google Scholar
• 1986 . Draft Recommended Maximum Contaminant Level (RMCL) Proposal , Office of Drinking Water (WH‐550) Washington, D.C. : U.S. Environmental Protection Agency .
   Google Scholar
• Hess , C. T. , Michel , J. , Horton , T. R. , Pritchard , H. M. and Coniglio , W. A. 1985 . The occurrence of radioactivity in public water supplies in the United States . Health Phys. , 48 : 50
   Web of Science ®Google Scholar
• Cothern , C. R. , Coniglio , W. A. and Marcus , W. L. Uncertainty in population risk estimates for environmental contaminants . Proc. of the 1984 Annu. Meet. Soc. Risk Analysis . New York : Plenum Press . in press
   Google Scholar
• Crouch , E. A. C. 1983 . Uncertainties in interspecies extrapolation of carcinogenicity . Environ. Health Perspect. , 50 : 321
   PubMed Web of Science ®Google Scholar
• Cothern , C. R. and Cothern , M. F. 1980 . Uncertainty — we do need it . Am. Biol. Teacher , 42 : 58
   Web of Science ®Google Scholar
• Beyth‐Marom , R. and Dekel , S. 1985 . An Elementary Approach to Thinking Under Uncertainty , Hillsdale, N.J. : Lawrence Erlbaum Assoc. .
   Google Scholar
• Giocoechea , A. , Krouse , M. R. and Antle , L. G. 1982 . An approach to risk and uncertainty in benefit‐cost analysis of water resource projects . Water Re sour. Res. , 18 : 791
   Web of Science ®Google Scholar
• Arrow , K. J. 1971 . The Theory of Risk Bearing , Chicago, Ill. : Markham Publishing .
   Google Scholar
• Morgan , M. G. , Henrion , M. , Morris , S. C. and Amaral , D. A. L. 1985 . Uncertainty in risk assessment . Environ. Sci. Technol. , 19 : 662
   PubMed Web of Science ®Google Scholar
• Cothern , C. R. and Schnare , D. W. The limitations of summary risk management data . paper given at the Symp. Scientific Praxis in Risk Management at the Annu. Meet. AAAS . May 1985 , Los Angeles. Washington, D.C. : U.S. Environmental Protection Agency . Office of Drinking Water, WH‐550
   Google Scholar
• Brown, R. N. and Lorentzen, R. J., private communication.
   Google Scholar
• U.S. Environmental Protection Agency . 1984 . Radionuclides Background Information Document for Final Rules, NESHAP , Vol. 1 , Washington, D.C. : Office of Radiation Programs . EPA‐520/1–84–022–1
   Google Scholar
• Layton , D. W. , Daniels , J. I. , Anspaugh , L. R. and O'Brien , K. D. 1983 . Health and Environmental Effects Document on Geothermal Energy — 1982 Update , Report UCRL‐53363 Livermore, Calif. : Lawrence Livermore Laboratory .
   Google Scholar
• Mackay , P. and Paterson , S. 1984 . Spatial concentration distributions . Environ. Sci. Technol. , 18 : 207A
   PubMed Web of Science ®Google Scholar
• U.S. Environmental Protecton Agency . 1980 . Upgrading Environmental Radiation Data , Washington, D.C. : Office of Radiation Programs (ANR 460) . EPA 520/1–80–012
   Google Scholar
• Scroggin , D. G. 1985 . EPA health risk policy will have broad impact . Legal Times , 19 July 15
   Google Scholar
• 1984 . Proposed guidelines for carcinogenic risk assessment . Fed. Regis. , 49 (227) : 46299
   Google Scholar
• Private communication, Office of Drinking Water (WH‐550), U.S. Environmental Protection Agency, Washington, D.C.
   Google Scholar
• Drury , J. S. , Reynolds , S. , Owen , P. T. , Ross , R. H. and Ensminger , J. T. 1981 . Uranium in U.S. Surface, Ground and Domestic Waters , Oak Ridge, Tenn. : Health and Environmental Studies Program, Information Center Complex, Oak Ridge National Laboratory . EPA 570/9081 ‐001, Report by the, available from NTIS, U.S. Department of Commerce, Springfield, Va.; the first volume is identified by the above number and the other three volumes of the 1980 page report list the data location and are identified by ORNL/EIS‐192
   Google Scholar
• Cothern , C. R. and Lappenbusch , W. L. 1983 . Occurrence of U in drinking water in the U.S. . Health Phys. , 45 : 89
   PubMed Web of Science ®Google Scholar
• Cothern , C. R. and Lappenbusch , W. L. 1984 . Compliance data for the occurrence of radium and gross alpha particle activity in drinking water supplies in the United States . Health Phys. , 46 : 503
   PubMed Web of Science ®Google Scholar
• King , P. T. , Michel , J. and Moore , W. S. 1982 . Groundwater geochemistry of 228Ra, 226Ra and 222Rn . Geochim. Cosmochim. Acta , 46 : 1173
   Web of Science ®Google Scholar
• Michel , J. and Pollman , C. D. 1982 . A Model for the Occurrence of ²²⁸Ra in Ground Water , Washington, D.C. : U.S. Environmental Protection Agency, Office of Drinking Water, WH‐550 . Environmental Science and Engineering Contract No. 81–227–270
   Google Scholar
• Michel , J. and Pollman , C. D. 1984 . A Model for the Occurence of ²²⁸Ra in Ground Water. II. Application to the North‐Central United States , Washington, D.C. : U.S. Environmental Protection Agency, Office of Drinking Water, WH‐550 . Environmental Science and Engineering Contract No. 81–227–270
   Google Scholar
• Cline , W. , Adamovitz , S. , Blackman , C. and Kahn , B. 1983 . Radium and uranium concentrations in the Georgia community water supplies . Health Phys. , 44 : 1
   PubMed Web of Science ®Google Scholar
• Horton , T. R. 1984 . Methods and Results of EPA's Study of Radon in Drinking Water , Montgomery, Ala. : Eastern Environmental Research Facility, U.S. Environmental Protection Agency, Office of Radiation Programs . EPA 520/5–83–027
   Google Scholar
• Krishniswami , S. , Graustein , W. C. , Turkeian , K. K. and Down , J. F. 1982 . Radium, thorium and radioactive lead isotopes in ground waters: application to the in‐situ determination of adsorption‐desorption rate constants and retardation factors . Water Resour. Res. , 18 : 1633
   Web of Science ®Google Scholar
• Langmuir , D. and Herman , J. S. 1981 . The mobility of thorium in natural waters at low temperatures . Geochim. Cosmochim. Acta , 44 : 1753
   Web of Science ®Google Scholar
• Kaufmann , R. F. , Eadie , G. G. and Russell , C. R. 1976 . Effects of U mining and milling on ground water in the Grants Mineral Belt, New Mexico . Ground Water , 14 : 86
   Google Scholar
• Rowland , R. E. , Stehney , A. F. and Lucas , H. F. Jr. 1983 . Dose‐response relationships for radium induced bone sarcomas . Health Phys. , 44 (Suppl. 1) : 15
   PubMed Web of Science ®Google Scholar
• Sharpe , W. D. 1983 . Chronic radium intoxication: radium osteilitis and cancer in relation to 226Ra burden . Health Phys. , 44 (Suppl. 1) : 149
   PubMed Web of Science ®Google Scholar
• Sullivan , R. E. , Nelson , N. S. , Ellett , W. H. , Dunning , D. E. Jr. , Leggett , R. W. , Yalcintas , M. G. and Eckerman , K. F. 1981 . Estimates of Health Risk From Exposure to Radioactivity Pollutants , Oak Ridge, Tenn. : Oak Ridge National Laboratory . ORNL/TM‐7745
   Google Scholar
• NIOSH, National Institute for Occupational Safety and Health/National Institute of Environmental Health Sciences . 1984 . Radon daughter exposure and respiratory cancer‐quantitative and temporal aspects , Joint Monograph No. 1 Springfield, Va. : NTIS, National Technical Information Service .
   Google Scholar
• National Academy of Sciences . 1976 . Health Effects of Alpha Emitting Particles in the Respiratory Tract , U.S. Environmental Protection Agency Document 520/4–76–013 Washington, D.C. : Office of Radiation Programs .
   Google Scholar
• Jorgensen , H. S. 1973 . A study of mortality from lung cancer among miners in Kiruna, 1950–1970 . Work Environ. Health , 10 : 126
   Google Scholar
• Snihs , J. O. 1975 . “ The significance of Radon and its progeny as natural radiation sources in Sweden ” . In Noble Gases , National Environmental Research Center Report CONF‐730915 Edited by: Stanley , R. E. and Moghissi , A. A. Springfield, Va. : National Technical Information Service .
   Google Scholar
• Renard , K. B. 1974 . Respiratory cancer mortality in an iron mine in northern Sweden . Ambio , 3 : 67
   Google Scholar
• Evans , R. D. , Harley , J. H. , Jacobi , W. , McLean , A. S. , Mills , W. A. and Stewart , C. G. 1981 . Estimate of risk from environmental exposure to radon‐222 and its decay products . Nature (London) , 290 : 98
   PubMed Web of Science ®Google Scholar
• Wright , E. S. and Couves , C. M. 1977 . Radiation induced carcinoma of the lung—the St. Lawrence tragedy . J. Thorac. Cardiovasc. Surg. , 74 : 495
   PubMed Web of Science ®Google Scholar
• Walsh , P. J. 1979 . Dose conversion factors for radon daughters . Health Phys. , 36 : 601
   PubMed Web of Science ®Google Scholar
• National Council on Radiation Protection and Measurements (NCRP) . 1984 . Evaluation of Occupational and Environmental Exposures to Radon and Radon Daughters in the United States , NCRP Report 78 Washington, D.C.
   Google Scholar
• U.S. Environmental Protection Agency . 1984 . “ Draft Final Report ” . In Evaluation of Waterborne Radon Impact on Indoor Air Quality and Assessment of Control Options , Research Triangle Park, N.C. : Hazardous Air and Industrial Technology Branch, Industrial Environmental Research Laboratory .
   Google Scholar
• Crawford‐Brown, D. J. and Cothern, C. R., in preparation.
   Google Scholar
• Lerman , A. 1972 . Strontium‐90 in the Great Lakes: concentration‐time model . J. Geophys. Res. , 77 : 3256
   Google Scholar
• Edgington, D., private communication.
   Google Scholar
• National Council on Radiation Protecton and Measurements . 1984 . Radiological Assessment: Predicting the Transport, Bioaccumulation and Uptake by Man of Radionuclides Released to the Environment , Report No. 76 Washington, D.C.
   Google Scholar
• Coniglio, W. A., private communication.
   Google Scholar
• National Toxicology Program (NTP) . May 1983 . NTP Technical Report on The Carcinogenicity Bioassay of 1,2‐Dichloropropane in F344/N Rats and B6C3F, Mice (Gavage Study) , May , National Institutes of Health Publication No. 83–2519 .
   Google Scholar
• Daly , I. W. , Hagan , G. K. and Plutnick , R. 1981 . An Eighteen‐Month Chronic Feeding Study of Alachlor in Mice: Project No. 77–1064 , Washington, D.C. : Monsanto Co. . Final Report, unpublished study received July 1, 1981 under EPA Reg. No. 524–285, submitted by, CDL: 070168‐A, 0700169
   Google Scholar
• Daly , I. W. , McCandless , J. B. and Jonassen , H. 1982 . A Chronic Feeding Study of Alachlor in Rats , Washington, D.C. : Monsanto Co. . Project No. 77–2065. Final Report, unpublished study received Jan. 5, 1982 under EPA Reg. No. 524–285, prepared by Bio‐Dynamics, Inc., submitted by, CDL:070586‐A, 070587,8,9 & 90
   Google Scholar
• Stout , L. D. 1983 . A Chronic Study of Alachlor Administered in Feed to Long Evans Rats , Washington, D.C. : Monsanto Co. . EHL #800218, Project #ML‐80–186, Report MSL‐3282/3284, Vol. 3, unpublished study received Feb. 28, 1984 under EPA Reg. No. 524–316, prepared by Monsanto Environmental Health Laboratory (EHL), submitted by, CDL:252498
   Google Scholar
• Hazelton Laboratories America, Inc. October 29 1977 . 104 Week Dietary Study in Rats, 1,2‐Dibromo‐3‐Chloropropane (DBCP) , Final Report October 29 , Midland, Mich. : DOW Chemical Co. . unpublished report submitted to
   Google Scholar
• Marcus, W. L., private communication.
   Google Scholar
• Johnston , P. , Letkiewicz , F. and Borum , D. 1984 . Occurrence of Pesticides in Drinking Water, Food and Air , Interim Draft Report Washington, D.C. : U.S. Enviromental Protection Agency . Prepared by JRB Associates, McLean, Va. for the Office of Drinking Water, WH‐550
   Google Scholar
• U.S. Environmental Protection Agency . 1983 . Ethylene Dibromide (EDB) Position Document 4 , Washington, D.C. : Office of Pesticides Programs .
   Google Scholar
• U.S. Environmental Protection Agency . 1984 . Ethylene Dibromide (EDB), Scientific Support and Decision Document for Grain and Grain Milling Fumigation Uses , Washington, D.C. : Office of Pesticides Programs .
   Google Scholar
• Marcus , W. L. and Cothern , C. R. 1985 . The characteristics of an adverse effect; using lead as an example . Drug Metab. Rev. , 16 : 423
   PubMed Web of Science ®Google Scholar
• Azar , A. , Trochimowicz , H. J. and Maxfield , M. E. Review of lead studies in animals carried out at Haskell Laboratory: two year feeding study and response to hemorrhage study . Environmental Health Aspects of Lead: Proc. Int. Symp. Edited by: Barth , D. , Berlin , A. , Engel , R. , Recht , P. and Smeets , J. pp. 199 Commission of the European Communities, Centre for Information & Documentation .
   Google Scholar
• Rowe , W. D. , ed. 1983 . Evaluation Methods for Environmental Standards , Boca Raton, Fla. : CRC Press .
   Google Scholar
• Selikoff , I. S. 1979 . Mortality experience of insulation workers in the United States and Canada, 1943–1976 . Ann. N.Y. Acad. Sci. , 330 : 91
   PubMedGoogle Scholar
• Doll , R. and Peto , J. 1985 . Asbestos Effects on Health of Exposure to Asbestos , Bootle, Merseyside : Health and Safety Commission, St. Hugh's House, Stanley Precinct . England
   Google Scholar
• National Academy of Sciences . 1983 . Drinking Water and Health Vol. 5 , Washington, D.C.
   Google Scholar
• Polissar , L. , Severson , R. K. , Boatman , E. S. and Hutchinson , F. 1984 . Case control study of asbestos in drinking water and cancer risk . Am. J. Epidemiol. , 119 : 456
   PubMed Web of Science ®Google Scholar
• National Toxicology Program . 1984 . Technical Report on the Toxicology and Carcinogenesis Studies of Chrysotile Asbestos in F344/N Rats , Research Triangle Park, N.C. : DHHS . NTP TR 295
   Google Scholar
• 1984 . Water‐Related Disease Outbreaks , Atlanta, Ga. : Centers for Disease Control, Enteric Diseases Branch, Division of Bacterial Diseases, Center for Infectious Diseases .
   Google Scholar
• Lumbers , J. P. and Harris , R. B. Risk and Uncertainty in the Master Planning of Sewerage and Sanitation for Developing Countries . paper presented at the meeting of the Metropolitan District Centre in London . January 22 . London, , England : Public Health and Water Resource Engineering, Imperial College .
   Google Scholar
• Gerba, C. P., unpublished report.
   Google Scholar
• U.S. Environmental Protection Agency . 1984 . Assessment of Chloroform Source Categories , Report to U.S. Environmental Protection Agency Standards and Engineering Division Research Triangle Park, N.C. : Office of Air Quality, Planning and Standards .
   Google Scholar
• Jorgenson , T. A. , Rushbrook , C. J. and Jones , D. C. L. 1982 . Dose‐response study of chloroform carcinogenesis in the mouse and rat, status report . Environ. Health Perspect. , 46 : 141
   PubMed Web of Science ®Google Scholar
• Jorgenson , T. A. , Meierhenry , E. F. , Rushbrook , C. J. , Bull , R. J. , Robinson , M. and Whitmore , C. E. 1985 . Carcinogenicity of chloroform in drinking water to male Osborne‐Mendel rats and female B6C3F1 mice . Fundam. Appl. Toxicol. , 5 : 760
   PubMedGoogle Scholar
• 1979 . NIPDWR: promulgation, trihalomethane . Fed. Regist. , 44 (23) : 68703
   Google Scholar
• Brown , L. and Rhead , M. 1979 . Liquid chromatographic determination of acrylamide monomer in natural and polluted aqueous environment . Analyst , 104 : 391
   Web of Science ®Google Scholar
• Johnson , K. A. , Gorzinski , S. J. , Bodner , K. M. and Campbell , R. A. 1984 . Acrylamide; a Two‐Year Drinking Water Chronic Toxicity‐Oncogenicity Study in Fischer 344 Rats , Final Report Midland, , U.S.A. : Mammalian and Environmental Toxicology Research Laboratory, Health and Environmental Sciences, DOW Chemical . Mich.
   Google Scholar
• Ruckelshaus , W. D. 1983 . Science Risk and Public Policy . speech before the National Academy of Sciences . June 22 1983 .
   Google Scholar
• National Research Council . 1983 . Risk Assessment in the Federal Government: Managing the Process , Washington, D.C. : National Academy Press .
   Google Scholar
• Taylor , M. R. 1984 . The role of law in risk management: a framework for managing uncertainty . Fundam. Appl. Toxicol. , 4 : 5408
   Google Scholar
• Cothern , C. R. and Marcus , W. L. 1985 . A discussion of some of the problems encountered in communicating risk assessments to decision makers . paper presented Annu. Meet. Society for Risk Analysis . October 1985 . to be published in the proceedings
   Google Scholar
• Beyth‐Marom , R. 1982 . How probable is probable? A numerical translation of verbal probability expressions . J. Forcasting , 1 : 257
   Web of Science ®Google Scholar
• Milvy , P. 1986 . A general guideline for management of risk from carcinogens . Risk Anal. , 6 : 69
   PubMed Web of Science ®Google Scholar
• Mills , W. A. 1985 . A regulatory consideration in radiation protection . Health Phys. , 48 : 701
   PubMed Web of Science ®Google Scholar
• Fiksel , J. , Barum , M. S. , Cox , L. A. and Miyares , R. F. September 7 1984 . Principles for Use of De Minimis Concepts in Risk Regulation , Draft Final Report September 7 , Washington, D.C. : submitted to the Division of Policy Research and Analysis, National Science Foundation .
   Google Scholar
• Golden , R. 1985 . Thresholds: to have or have not . presented Annu. Meet. AAAS . May 29 1985 , Los Angeles.
   Google Scholar
• Land , C. 1980 . Estimating cancer risks from low doses of ionizing radiation . Science , 209 : 1197
   PubMed Web of Science ®Google Scholar
• Cairns , T. 1980 . The ED01 study: introductions, objectives and experimental design . J. Environ. Pathol. Toxicol. , 3 : 1 and succeeding articles
   PubMed Web of Science ®Google Scholar
• National Council on Radiation Protection and Measurements, (NCRP) . 1975 . Natural Background Radiation in the United States , NCRP Report 45 Washington, D.C.
   Google Scholar
• National Council on Radiation Protection and Measurements, (NCRP) . 1984 . Exposures From the Uranium Series with Emphasis on Radon and Its Daughters , NCRP Report 77 Washington, D.C.
   Google Scholar
• The ideas and thoughts presented here are those of the author and do not necessarily reflect the policies of the U.S. Environmental Protection Agency.
   Google Scholar