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Research Article

Is There a Role for Twin Studies in the Molecular Genetics Era?

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Pages 318-323 | Published online: 03 Jul 2009

REFERENCES

  • Galton F. The history of twins as a criterion of the relative powers of nature and nurture. J Anthropol Inst 1875;6:391–406.
  • Merriman C. The intellectual resemblance of twins. Psychol Monogr 1924;33(5):1–58.
  • Rende RD, Plomin R, Vandenberg SG. Who discovered the twin method? Behav Genet 1990;20:277–85.
  • Watson JD, Crick FHC. A structure for deoxyribose nucleic acid. Nature 1953;171:737–8.
  • Plomin R. Nature and nurture: an introduction to human be- havioral genetics. Pacific Grove, California: Brooks/Cole, 1990.
  • Turkheimer E. Three laws of behavior genetics and what they mean. Curr Dir Psychol Sci 2000;9:160–4.
  • McGuffin P, Owen MJ, O’Donovan MC, Thapar A, Gottesman II, eds. Seminars in psychiatric genetics. London, England: Royal College of Psychiatrists, 1994.
  • Gottlieb G. Some conceptual deficiencies in “developmental” behavior genetics. Hum Devel 1995;38:131–41.
  • Gusella JF, Wexler NS, Conneally PM, Naylor SL, Anderson MA, Tanzi RE, et al. A polymorphic DNA marker genetically linked to Huntington’s disease. Nature 1983;306:234–8.
  • Beaudet A, Bowcock A, Buchwald M, Cavalli-Sforza L, Farrall M, King MC, et al. Linkage of cystic fibrosis to two tightly linked DNA markers: joint report from a collaborative study. Am J Hum Genet 1986;39:681–93.
  • Kunkel LM. Analysis of deletions in DNA from patients with Becker and Duchenne muscular dystrophy. Nature 1986; 322:73–7.
  • Sandbrink R, Hartmann T, Masters CL, Beyreuther K. Genes contributing to Alzheimer’s disease. Mol Psychiatry 1996; 1:27–40.
  • McPherson K, Steel CM, Dixon JM. ABC of breast diseases: breast cancer—epidemiology, risk factors and genetics. BMJ 1994;309:1003–6.
  • Crow TJ. Current status of linkage for schizophrenia: poly- genes of vanishingly small effect or multiple false positives? Am J Med Genet 1997;74:99–103.
  • Plomin R, Owen MJ, McGuffin P. The genetic basis of complex human behaviors. Science 1994;264:1733–9.
  • Schork NJ, Xu X. The use of twins in quantitative trait locus mapping. In: Spector TD, Snieder H, MacGregor AJ, eds. Ad- vances in twin and sib-pair analysis. London: Greenwich Med- ical Media, 2000:189–202.
  • Risch N. Genetic linkage and complex diseases, with special reference to psychiatric disorders. Genet Epidemiol 1990;7:3–16.
  • Gottesman II. Schizophrenia genesis: the origins of madness. New York: Freeman, 1991.
  • Tinbergen EA, Tinbergen N. Early childhood autism: an etho- logical approach. Berlin: Parey, 1972.
  • Folstein S, Rutter M. Genetic influences and infantile autism. Nature 1977;265:726–8.
  • Piven J. The broad autism phenotype: a complementary strat- egy for molecular genetic studies of autism. Am J Med Genet 2001;105:34–5.
  • Faraone SV, Green AI, Seidman LJ, Tsuang MT. “Schizotaxia”: clinical implications and new directions for research. Schizophr Bull 2001;27:1–18.
  • Arolt V, Lencer R, Nolte A, Mu¨ ller-Myhsok B, Purmann S, Schu¨ rmann M, et al. Eye tracking dysfunction is a putative phenotypic susceptibility marker of schizophrenia and maps to a locus on chromosome 6p in families with multiple occur- rence of the disease. Am J Med Genet 1996;67:564–79.
  • Freedman R, Coon H, Myles-Worsley M, Orr-Urtreger A, Olincy A, Davis A, et al. Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus. Proc Natl Acad Sci USA 1997;94:587–92.
  • Kaprio J, Koskenvuo M, Langinvainio H, Romanov K, Sarna S, Rose RJ. Genetic influences on use and abuse of alcohol: a study of 5638 adult Finnish twin brothers. Alcohol Clin Exp Res 1987;11:349–56.
  • Saccone NL, Kwon JM, Corbett J, Goate A, Rochberg N, Eden- berg HJ, et al. A genome screen of maximum number of drinks as an alcoholism phenotype. Am J Med Genet 2000;96:632–7.
  • Reich T, Edenberg HJ, Goate A, Williams JT, Rice JP, Van Eer- dewegh P, et al. Genome-wide search for genes affecting the risk for alcohol dependence. Am J Med Genet 1998;81:207–15.
  • Neale MC, Cardon LR. Methodology for genetic studies of twins and families. Dordrecht, Netherlands: Kluwer, 1992.
  • Cannon TD, Kaprio J, Lo¨nnqvist J, Huttunen M, Koskenvuo M. The genetic epidemiology of schizophrenia in a Finnish twin cohort: a population-based modeling study. Arch Gen Psychiatry 1998;55:67–74.
  • Plomin R, McClearn GE, eds. Nature, nurture, and psychol- ogy. Washington, DC: American Psychological Association, 1993.
  • Deater-Deckard K, Reiss D, Hetherington EM, Plomin R. Di- mensions and disorders of adolescent adjustment: a quantita- tive genetic analysis of unselected samples and selected ex- tremes. J Child Psychol Psychiatry 1997;38:515–25.
  • Livesley WJ, Jang KL, Vernon PA. Phenotypic and genetic structure of traits delineating personality disorder. Arch Gen Psychiatry 1998;55:941–8.
  • Reveley AM, Reveley MA, Clifford CA, Murray RM. Cerebral ventricular size in twins discordant for schizophrenia. Lancet 1982;1:540–1.
  • Suddath RL, Christison GW, Torrey EF, Casanova MF, Wein- berger DR. Anatomical abnormalities in the brains of mono- zygotic twins discordant for schizophrenia. N Engl J Med 1990;322:789–94.
  • McNeil TF, Cantor-Graae E, Torrey EF, Sjo¨stro¨m K, Bowler A, Taylor E, et al. Obstetric complications in histories of monozy- gotic twins discordant and concordant for schizophrenia. Acta Psychiatr Scand 1994;89:196–204.
  • Bracha HS, Torrey EF, Bigelow LB, Lohr JB, Linington BB. Subtle signs of prenatal maldevelopment of the hand ectoderm in schizophrenia: a preliminary monozygotic twin study. Biol Psychiatry 1991;30:719–25.
  • Gottesman II, Bertelsen A. Confirming unexpressed genotypes for schizophrenia: risks in offspring of Fischer’s Danish identi- cal and fraternal discordant twins. Arch Gen Psychiatry 1989; 46:867–72.
  • Stabenau JR, Pollin W. Heredity and environment in schizo- phrenia, revisited: the contribution of twin and high-risk stud- ies. J Nerv Ment Dis 1993;181:290–7.
  • Plomin R, Daniels D. Why are children in the same family so different from one another? Behav Brain Sci 1987;10:1–16.
  • Tsujita T, Niikawa N, Yamashita H, Imamura A, Hamada A, Nakane Y, et al. Genomic discordance between monozygotic twins discordant for schizophrenia. Am J Psychiatry 1998; 155:422–4.
  • MacGregor AJ, Snieder H, Schork NJ, Spector TD. Twins: novel uses to study complex traits and genetic diseases. Trends Genet 2000;16:131–4.
  • Anonymous. Gemini Genomics & large scale biology identify proteomic drug target leads in 5 common human diseases [Press release]. Cambridge, England: Gemini Genomics, 14 September 2000 [Available on the World Wide Web at http:// www.gemini_genomics.com/press/lsb.htm].

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