Advanced search
Publication Cover
Free Radical Research Volume 36, 2002 - Issue 10
Submit an article Journal homepage
40
Views
12
CrossRef citations to date
0
Altmetric
Research Article

Local Pharmacokinetic Analysis of a Stable Spin Probe in Mice by In Vivo L-band ESR with Surface-coil-type Resonators

Masayuki Kamatari Department of Analytical and Bioinorganic Chemistry, Kyoto Pharmaceutical University, 5 Nakauchi-cho, Misasagi, Yamashina-ku, Kyoto 607-8414, Japan
,
Hiroyuki Yasui Department of Analytical and Bioinorganic Chemistry, Kyoto Pharmaceutical University, 5 Nakauchi-cho, Misasagi, Yamashina-ku, Kyoto 607-8414, Japan
,
Tateaki Ogata Department of Chemistry and Chemical Engineering, Faculty of Engineering, Yamagata University, 4-9-16 Jyonan, Yonezawa, Yamagata 992-8510, Japan
&
Hiromu Sakurai Department of Chemistry and Chemical Engineering, Faculty of Engineering, Yamagata University, 4-9-16 Jyonan, Yonezawa, Yamagata 992-8510, Japan
Pages 1115-1125 | Published online: 07 Jul 2009

  • Halliwell, B. and Gutteridge, J.M.C. (1998) Free Radicals in Biology and Medicine, 3rd Ed. (Oxford Science Publications, London).
  • Rice-Evans, C.A., Burdern, R.H., eds, (1994) Free Radical Damage and its Control (Elsevier, Amsterdam).
  • Saifutdinov, R.G., Larina, L.I., Vakul'skaya, T.I. and Voronkov, M.G. (2001) Electron Paramagnetic Resonance in Biochemistry and Medicine (Kluwer Academic/Plenum Publishers, New York).
  • Ono, M., Ogata, T., Hsieh, K., Suzuki, M., Yoshida, E. and Kamada, H. (1986) "L-band ESR spectrometer using a loopgap resonator for in vivo analysis", Chem. Lett., 491-494.
  • Zweier, J.L. and Kuppusamy, P. (1998) "Electron paramagnetic resonance measurements of free radicals in the intact beating heart: a technique for detection and characterization of free radicals in whole biological tissues", Proc. Natl Acad. Sci. USA 85, 5703-5708.
  • Rosen, G.M., Halpern, H.J., Brunsting, L.A., Spencer, D.P., Strauss, K.E., Bowman, M.K. and Wechsler, A.S. (1988) "Direct measurement of nitroxide pharmacokinetics in isolated hearts situated in a low-frequency electron spin resonance spectrometer: implications for spin trapping and in vivo oxymetry", Proc. Natl Acad. Sci. USA 85, 7772-7776.
  • Hirata, H. and Ono, M. (1996) "Resonance frequency estimation of a bridged loop-gap resonator used for magnetic resonance measurements", Rev. Sci. Instrum. 67, 73-78.
  • Berliner, L.J. and Wan, X. (1989) "In vivo pharmacokinetics by electron magnetic resonance spectroscopy", Magn. Reson. Med. 9, 430-434.
  • Ferrari, M., Colacicchi, S., Gualtieri, G., Santini, M.T. and Sotgiu, A. (1990) "Whole mouse nitroxide free radical pharmacokinetics by low frequency electron paramagnetic resonance", Biochem. Biophys. Res. Commun. 166,168-173.
  • Kuppusamy, P., Chzhan, M., Vij, K., Shteynbuk, M., Lefer, D.J., Giannella, E. and Zweier, J.L. (1994) "Three-dimensional spectral-spatial EPR imaging of free radicals in the heart: a technique for imaging tissue metabolism", Proc. Natl Acad. Sci. USA 91, 3388-3392.
  • Halpern, HJ., Peric, M., Yu, C., Barth, E.D., Chandramouli, G.V.R., Makinen, M.W and Rosen, G.M. (1996) "In vivo spinlabel murine pharmacodynamics using low-frequency electron paramagnetic resonance imaging", Biophys. J. 71, 403-409.
  • Ishida, S., Matsumoto, S., Yokoyama, H., Mori, N., Kumashiro, H., Tsuchihashi, N., Ogata, T., Yamada, M., Ono, M., Kitajima, T., Kamada, H. and Yoshida, E. (1992) "An ESR-CT imaging of the head of a living rat receiving an administration of a nitroxide radical", Magn. Reson. Imaging 10,109-114.
  • Yokoyama, H., Ogata, T, Tsuchihashi, N., Hiramatsu, M. and Mori, N. (1996) "A spatiotemporal study on the distribution of intraperitoneally injected nitroxide radical in the rat head using an in vivo ESR imaging system", Magn. Reson. Imaging 14, 559-563.
  • Sano, H., Naruse, M., Matsumoto, K., Oi, T. and Utsumi, H. (2000) "A new nitroxyl-probe with high retention in the brain and its application for brain imaging", Free Radie. Biol. Med. 28, 959-969.
  • Yokoyama, H., Itoh, O., Ogata, T, Obara, H., OhyaNishiguchi, H. and Kamada, H. (1997) "Temporal brain imaging by a rapid scan ESR-CT system in rats receiving intraperitoneal injection of a methyl ester nitroxide radical", Magn. Reson. Imaging 15,1079-1084.
  • Togashi, H., Shinzawa, H., Ogata, T, Matsuo, T, Ohno, S., Saito, K., Yamada, N., Yokoyama, H., Noda, H., Oikawa, K., Kamada, H. and Takahashi, T. (1998) "Spatiotemporal measurement of free radical elimination in the abdomen using an in vivo ESR-CT imaging system", Free Radic. Biol. Med. 25,1-8.
  • Yokoyama, H., Lin, Y, Itoh, O., Ueda, Y, Nakajima, A., Ogata, T., Sato, T., Ohya-Nishiguchi, H. and Kamada, H. (1999) "EPR imaging for in vivo analysis of a half-life of a nitroxide radical in the hippocampus and cerebral cortex of rats after epileptic seizures", Free Radie. Biol. Med. 27, 442-448.
  • Miura, Y, Anzai, K., Takeshita, S. and Ozawa, T. (1997) "A novel lipophilic spin probe for the measurement of radiation damage in mouse brain using in vivo electron spin resonance (ESR)", FEBS Lett. 419, 99-102.
  • Phumala, N., Ide, T. and Utsumi, H. (1999) "Noninvasive evaluation of in vivo free radical reactions catalyzed by iron using in vivo ESR spectroscopy", Free Radic. Biol . Med. 26, 1209-1217.
  • Miura, Y, Anzai, K., Ueda, J.I. and Ozawa, T. (2001) "Pathophysiological significance of in OWO ESR signal decay in brain damage caused by X-irradiation: radiation effect on nitroxyl decay of a lipophilic spin probe in the head region", Biochim. Biophys. Acta 1525,167-172.
  • Nishino, N., Yasui, H. and Sakurai, H. (1999) "In vivo L-band ESR and quantitative pharmacokinetic analysis of stable spin probes in rats and mice", Free Radie. Res. 31, 35-51.
  • Quaresima, V., Alecci, M., Ferrari, M. and Sotgiu, A. (1992) "Whole rat electron paramagnetic resonance imaging of a nitroxide free radical by a radio frequency (280 MHz) spectrometer", Biochem. Biophys. Res. Commun. 183, 829-835.
  • Alecci, M., Ferrari, M., Quaresima, V, Sotgiu, A. and Ursini, C.L. (1994) "Simultaneous 280 MHz EPR Imaging of rat organs during nitroxide free radical clearance", Biophys. J. 67, 1274-1279.
  • Hirata, H., Iwai, H. and Ono, M. (1995) "Analysis of a flexible surface-coil-type resonator for magnetic resonance measurements", Rev. Sci. Instrum. 64, 4529-4534.
  • Lin, Y, Yokoyama, H., Ishida, S., Tsuchihashi, N. and Ogata, T. (1997) "In vivo spin resonance analysis of nitroxide radicals injected into a rat by a flexible surface-coil-type resonator as an endoscope- or a stethoscope-like device", Magn. Reson. Mater. Phys. Biol. Med. 5, 99-103.
  • Honzak, L., Sentjurc, M. and Swartz, H.M. (2000) "In vivo EPR of topical delivery of a hydrophilic substance encapsulated in multilamellar liposomes applied to the skin of hairless and normal mice", J. Control. Release 66, 221-228.
  • Tada, M., Yokoyama, H., Toyoda, Y, Ohya, H., Ito, T. and Ogata, T. (2000) "Surface-coil-type resonators for in vivo temporal ESR measurements in different organs of nitroxidetreated rats", Appl. Magn. Reson. 18, 575-582.
  • Yokoyama, H., Tada, M., Sato, T., Ohya, H. and Kamada, H. (2000) "Non-invasive ESR measurements for in vivo kinetic studies of a nitroxide radical in the liver of a rat by a surfacecoil-type resonator under a field gradient", Chem. Lett., 1000-1001.
  • Tada, M., Shiraishi, T, Yokoyama, H., Ohya, H., Ogata, T. and Kamada, H. (2001) "Nondestructive real-time monitoring of the redox status in a potted plant by using a surface-coil-type ESR resonator", Chem. Lett., 1122-1123.
  • Yamaoka, K., Tanigawara, Y and Nakagawa, T. (1981) "A pharmacokinetic analysis program (MULTI) for microcomputer", J. Pharmacobio-Dyn. 4, 879-885.
  • Cutler, DJ. (1978) "On the definition of the compartment model concept in pharmacokinetics", J. Theor. Biol. 73, 329-345.
  • Gibaldi, M. and Perrier, D. (1982) "Pharmacokinetics", Drug and the Pharmaceutical Sciences, 2nd ed. (Marcel Dekker, New York) Vol. 15, pp. 45-109.
  • Verotta, D., Sheiner, L.B., Ebling, W.F. and Stanski, D.R. (1989) "A semiparametric approach to physiological flow models", /. Pharmacokinet. Biopharm. 17, 463-491.
  • Björkman, S., Stanski, D.R., Harashima, H., Dowrie, R., Harapat, S.R., Wada, D.R. and Ebling, W.F. (1993) "Tissue distribution of fentanyl and alfentanil in the rat cannot be described by a blood flow limited model", J. Pharmacokinet. Biopharm. 21, 255-279.
  • Lassen, N.A. and Perl, W (1979) Tracer Kinetic Methods in Medical Physiology (Raven Press, New York), pp. 76-99.
  • McNamara, P.J., Fleishaker, J.C. and Hayden, T.L. (1987) "Mean residence time in peripheral tissue", J. Pharmacokinet. Biopharm. 15, 439-450.
  • He, Y.L., Tanigawara, Y, Yasuhara, M. and Hori, R. (1991) "Effect of folinic acid on tissue residence and excretion of methotrexate in rats", Drug Metab. Dispos. 19, 729-734.
  • Takechi, K., Tamura, H., Yamaoka, K. and Sakurai, H. (1997) "Pharmacokinetic analysis of free radicals by in vivo BCM (Blood Circulation Monitoring)-ESR method", Free Radie. Res. 26, 483-496.
  • Sakurai, H., Takechi, K., Tsuboi, H. and Yasui, H. (1999) "ESR characterization and metallokinetic analysis of Cr(V) in the blood of rats given carcinogen chromate(VI) compounds", J. Inorg. Biochem. 76, 71-80.
  • Yasui, H., Takechi, K. and Sakurai, H. (2000) "Metallokinetic analysis of disposition of vanadyl complexes as insulinmimetics in rats using BCM-ESR method", J. Inorg. Biochem. 78,185-196.
  • Takino, T., Yasui, H., Yoshitake, A., Hamajima, Y, Matsushita, R., Takada, J. and Sakurai, H. (2001) "A new halogenated antidiabetic vanadyl complex,bis(5-iodopicolinato) oxovanadium(IV): in vitro and in vivo insulinomimetic evaluations and metallokinetic analysis", J. Biol. Inorg. Chem. 6,133-142.
  • Quaresima, Y, Takehara, H., Tsushima, K., Ferrari, M. and Utsumi, H. (1996) "In vivo detection of mouse liver nitric oxide generation by spin trapping electron paramagnetic resonance spectroscopy", Biochem. Biophys. Res. Commun. 221, 729-734.
  • Yoshimura, T., Fujii, H., Takayama, F., Oikawa, K. and Kamada, H. (1996) "In vivo EPR detection and imaging of endogenous nitric oxide in lipopolysaccharide-treated mice", Nat. Biotechnol. 14, 992-994.
  • Wallis, G., Brackett, D., Lerner, M., Kotake, Y, Bolli, R. and McCay, RB. (1996) "In vivo spin trapping of nitric oxide generated in the small intestine, liver, and kidney during the development of endotoxemia: a time-course study", Shock 6, 274-278.
  • Takeshita, K., Utsumi, H. and Hamada, A. (1987) "Dynamic properties of the haptenic site of lipid haptens in phosphatidylcholine membranes. Their relation to the phase transition of the host lattice", Biophys. J. 52,187-197.
  • Vianello, F, Momo, F., Scarpa, M. and Rigp, A. (1995) "Kinetics of nitroxide spin label removal in biological systems: an in vitro and in vivo ESR study", Magn. Reson. Imaging 13, 219-226.
  • Fuchs, J., Groth, N., Herrling, T. and Zimmer, G. (1997) "Electron paramagnetic resonance studies on nitroxide radical 2,2,5,5-tetramethyl-4-piperidin-l-oxyl (TEMPO) redox reactions in human skin", Free Radie. Biol. Med. 22, 967-976.
  • Iannone, A., Tomasi, A. and Swartz, H.M. (1990) "Metabolism of nitroxide spin labels in subcellular fraction of rat liverI. Reduction by microsomes", Biochim. Biaphys. Ada 1034, 285-289.
  • Iannone, A., Tomasi, A., Vannini, V. and Swartz, H.M. (1990) "Metabolism of nitroxide spin labels in subcellular fractions of rat liver. II. Reduction in the cytosol", Biochim. Biophys. Acta 1034, 290-293.
  • Matsumoto, S., Mori, N., Tsuchihashi, N., Ogata, T., Lin, Y, Yokoyama, H. and Ishida, S. (1998) "Enhancement of nitroxide-reducing activity in rats after chronic administration of vitamin E, vitamin C, and idebenone examined by an in vivo electron spin resonance technique", Magn. Reson. Med. 40, 330-333.
  • Togashi, H., Matsuo, T., Shinzawa, H., Takeda, Y, Shao, L., Oikawa, K., Kamada, H. and Takahashi, T. (2000) "Ex vivo measurement of tissue distribution of a nitroxide radical after intravenous injection and its in vivo imaging using a rapid scan ESR-CT system", Magn. Reson. Imaging 18, 151-156.
  • Halpern, H.J., Yu, C., Barth, E., Peric, M. and Rosen, G.M. (1995) "In situ detection, by spin trapping, of hydroxyl radical markers produced from ionizing radiation in the tumor of a living mouse", Proc. Natl Acad. Sci. USA 92, 796-800.
  • Fink, B., Dikalov, S. and Bassenge, E. (2000) "A new approach for extracellular spin trapping of nitroglycerin-induced Superoxide radicals both in vitro and in vivo", Free Radie. Biol. Med. 28, 121-128.
  • Yokoyama, H., Itoh, O., Aoyama, M., Obara, H., Ohya, H. and Kamada, H. (2000) "In vivo EPR imaging by using an acylprotected hydroxylamine to analyze intracerebral oxidative stress in rats after epileptic seizures", Magn. Reson. Imaging 18, 875-879.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.