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Research Article

The Antioxidant Activity of Regularly Consumed Fruit and Vegetables Reflects their Phenolic and Vitamin C Composition

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Pages 217-233 | Published online: 07 Jul 2009

  • Macheix, J.-J., Fleuriet, A. and Billot, J. (1990) Fruit Phenolics(CRC Press, Boca Raton, FL).
  • Hertog, M.G.L., Hollman, P.C.H. and Katan, M.B. (1992)"Content of potentially anticarcinogenic flavonoids of 28vegetables and 9 fruits commonly consumed in The Netherlands", J. Agric.Food Chem. 40, 2379-2383.
  • Clifford, M.N. (1999) "Chlorogenic acids and other cinna-mates-nature, occurrence and dietary burden", J. Sci. FoodAgric. 79, 362-372.
  • Tomas-Barberan, F.A. and Clifford, M.N. (2000) "Flavanones,chalcones and dihydrochalcones--nature, occurrence anddietary burden", J. Sci. Food Agric. 80, 1073-1080.
  • Clifford, M.N. (2000) "Anthocyanins-nature, occurrenceand dietary burden", J. Sci. Food Agric. 80, 1063-1072.
  • Hollman, P.C.H. and Arts, I.C.W. (2000) "Flavonols, flavonesand flavanols--nature, occurrence and dietary burden", J. Sci.Food Agric. 80, 1081-1093.
  • Harborne, J.B. and Mabry, T.J. (1982) The Flavonoids:Advances in Research (Chapman & Hall, London).
  • Gey, K.F., Puska, P., Jordan, P. and Moser, U.K. (1991) "Inversecorrelation between plasma Vitamin E and mortality fromischemic-heart-disease in crosscultural epidemiology", Am.J. Clin. Nutr. 53, S326-S334.
  • Ziegler, R.G. (1991) "Vegetables, fruits and carotenoids andthe risk of cancer", Am. J. Clin. Nutr. 53, 251S-259S.
  • Gaziano, J.M., Manson, J.E., Buring, J.E. and Hennekens, C.H.(1992) "Dietary antioxidants and cardiovascular disease",Ann. New York Acad. Sci. 669, 249-259.
  • Gaziano, J.M. and Hennikens, C.H. (1996) "Update on dietary antioxidants and cancer", Pathol. Biol. 44, 42-45.
  • Gandini, S., Merzenich, H., Robertson, C. and Boyle, P. (2000) "Meta-analysis of studies on breast cancer risk and diet: the role of fruit and vegetable consumption and the intake of associated micronutrients", Eur. J. Cancer 36, 636-646.
  • Joseph, J.A., Shukitt-Hale, B., Desinova, N.A., Prior, R.L., Cao, G., Martin, A., Taglialatela, G. and Bickford, P.C. (1998) "Long-term dietary strawberry, spinach, or Vitamin E supplementation retards the onset of age-related neuronal signal-transduction and cognitive behavioural deficits", J. Neurosci. 18, 8047-8055.
  • Cao, Y. and Cao, R. (1999) "Angiogenesis inhibited by drinking tea", Nature 398, 381.
  • Fuhrman, B., Lavy, A. and Aviram, M. (1995) "Consumption of red wine with meals reduces the susceptibility of human plasma and LDL to lipid peroxidation", Am. J. Clin. Nutr. 61, 549-554.
  • Gaziano, J.M. (1996) "Antioxidants in cardiovascular disease: randomized trials", Nutrition 12, 583-588.
  • Hertog, M.G., Kromhout, D., Aravinis, C., Blackburn, H., Buzina, R., Fidanza, F., Giampaoli, S., Jansen, A., Menotti, A., Nedeljkovic, S., Pekkarinen, M., Simic, B.S., Toshima, H., Feskens, E.J.M., Hollman, P.C.H. and Katan, M.B. (1995) "Flavonoid intake and long-term risk of coronary-heartdisease and cancer in the seven countries study", Arch. Intern. Med. 155, 381-386.
  • Middleton, Jr., E., Kandaswami, C. and Theoharides, T.C. (2000) "The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer", Pharmacol. Rev. 52, 673-751.
  • Rice-Evans, C.A., Miller, N.J. and Paganga, G. (1996) "Structure-antioxidant activity relationships of flavonoids and phenolic acids", Free Radic. Biol. Med. 20, 933-956.
  • Visioli, F., Bellomo, G. and Galli, C. (1998) "Free radicalscavenging properties of olive oil polyphenols", Biochem. Biophys. Res. Commun. 247, 60-64.
  • Jovanovic, S.V., Steenken, S., Simic, M.C. and Hara, Y. (1998) "Antioxidant properties of flavonoids: reduction potentials and electron transfer reactions of flavonoids radicals", In: Rice-Evans, C.A. and Packer, L., eds, Flavonoids in Health and Disease (Marcel Dekker, New York), pp 137-161.
  • Paganga, G., Miller, N. and Rice-Evans, C. (1999) "The polyphenolic content of fruit and vegetables and their antioxidant activities. What does a serving constitute?", Free Radic. Res. 30, 153-162.
  • Cao, G., Sofic, E. and Prior, R.L. (1996) "Antioxidant capacity of tea and common vegetables", J. Agric. Food Chem. 44, 3426-3431.
  • Wang, H., Cao, G. and Prior, R.L. (1996) "Total antioxidant capacity of fruits", J. Agric. Food Chem. 44, 701-705.
  • Halliwell, B. and Gutteridge, J.M.C. (1999) Free Radicals in Biology and Medicine (Oxford University Press, New York).
  • Hollman, P.C.H. and Katan, M.B. (1997) "Absorption, metabolism and health effects of dietary flavonoids in man", Biomed. Pharmacother. 51, 305-310.
  • Nielsen, S.E., Kall, M., Justesen, U., Schou, A. and Dragsted, L.O. (1997) "Human absorption and excretion of flavonoids after broccoli consumption", Cancer Lett. 114, 173-174.
  • Olthof, M.R., Hollman, P.C.H. and Katan, M.B. (2001) "Chlorogenic acid and caffeic acid are absorbed in humans", J. Nutr. 131, 66-71.
  • Hollman, P.C.H., Gaag, M.V.D., Mengelers, M.J.B., van Trijp, J.M.P., de Vries, J.H.M. and Katan, M.B. (1996) "Absorption and disposition kinetics of the dietary antioxidant quercetin in man", Free Radic. Biol. Med. 21, 703-707.
  • Murkovic, M., Toplak, H., Adam, U. and Pfannhauser, W (2000) "Analysis of anthocyanins in plasma for determination of their bioavailability", J. Food Compos. Anal. 13, 291-296.
  • Scalbert, A. and Williamson, G. (2000) "Dietary intake and bioavailability of polyphenols", J. Nutr. 130, 2073S-2085S.
  • Rechner, A.R., Spencer, J.P.E., Kuhnle, G., Hahn, U. and RiceEvans, C.A. (2001) "Novel biomarkers of the metabolism of caffeic acid derivatives in vivo", Free Radic. Biol. Med. 30, 1213-1222.
  • Oldreive, C., Zhao, K.C., Paganga, G., Halliwell, B. and RiceEvans, C. (1998) "Inhibition of nitrous acid-dependent tyrosine nitration and DNA base deamination by flavonoids and other phenolic compounds", Chem. Res. Toxicol. 11, 1574-1579.
  • Speek, A.J., Schrijer, J. and Schreurs, W.H.P. (1984) "Fluorimetric determination of total Vitamin C in whole blood by high-performance liquid-chromatography with precolumn derivatization", J. Chromatogr. 305, 53-60.
  • Singleton, V.L. and Rossi, J.A. (1965) "Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents", Am. J. Enol. Vitic. 16, 144-158.
  • Re, R., Pellegrini, N., Proteggente, A.R., Pannala, A.S. and Rice-Evans, C.A. (1999) "Antioxidant activity applying an improved ABTS radical cation decolorization assay", Free Radic. Biol. Med. 26, 1231-1237.
  • Benzie, I.F.F. and Strain, J.J. (1999) "Ferric reducing/antioxidant power assay: direct measure of total antioxidant activity of biological fluids and modified version for simultaneous measurement of total antioxidant power and ascorbic acid concentration", Meth. Enzymol. 299, 15-27.
  • Cao, G., Verdon, C.P., Wu, A.H.B., Wang, H. and Prior, R.L. (1995) "Automated-assay of oxygen radical absorbance capacity with the COBAS FARA-II", Clin. Chem. 41, 1738-1744.
  • Hakkinen, S.H. and Torronen, A.R. (2000) "Content of flavonols and selected phenolic acid in strawberries and Vaccinium species: influence of cultivar, cultivation site and technique", Food Res. Int. 33, 517-524.
  • Merken, H.M. and Beecher, G.R. (2000) "Measurement of food flavonoids by high-performance liquid chromatography: a review" J. Agric. Food Chem. 48, 577-599.
  • Satue-Gracia, M.T., Heinonen, M. and Frankel, E.N. (1997) "Anthocyanins as antioxidants on human low-density lipoprotein and lecithin-liposome systems", J. Agric. Food Chem. 45, 3362-3367.
  • Ghiselli, A., Nardini, M., Baldi, A. and Scaccini, C. (1998) "Antioxidant activity of different phenolic fractions separated from an Italian red wine", J. Agric. Food Chem. 46, 361-367.
  • Bronner, W.E. and Beecher, G.R. (1995) "Extraction and measurement of prominent flavonoids in orange and grapefruit concentrates", J. Chromatogr. A 705, 247-256.
  • Justesen, U., Knuthsen, P. and Leth, T. (1998) "Quantitative analysis of flavonols, flavones and flavanones in fruits, vegetables and beverages by high-performance liquid chromatography with photo-diode array and mass spectrometric detection", J. Chromatogr. A 799, 101-110.
  • Moon, J.-H., Nakata, R., Oshima, S., Inakuma, T. and Terao, J. (2000) "Accumulation of quercetin conjugates in blood plasma after short-term ingestion of onion by women", Am. J. Physiol--Regulat., Integr. Camp. Physiol. 279, R461-R467.
  • Price, K.R., Casuscelli, F., Colquhoun, IJ. and Rhodes, M.J.C. (1997) "Hydroxycinnamic acid esters from broccoli florets", Phytochemistry 45, 1683-1687.
  • Ferreres, F., Castaner, M. and Tomás-Barberán, FA. (1997) "Acylated flavonol glycosides from spinach leaves (Spinacia oleracea)", Phytochemistry 45, 1701-1705.
  • Nielsen, J.K., Nørbaek, R. and Olsen, C.E. (1998) "Kaempferol tetraglucosides from cabbage leaves", Phytochemistry 49, 2171-2176.
  • Nielsen, J.K., Olsen, C.E. and Petersen, M.K. (1993) "Acylated flavonol glycosides from cabbage leaves", Phytochemistry 34, 539-544.
  • Plumb, G.W., Price, K.R., Rhodes, M.J.C. and Williamson, G. (1997) "Antioxidant properties of the major polyphenolic compounds in broccoli", Free Radic. Res. 27, 429-435.
  • Stewart, A.J., Bozonnet, S., Mullen, W., Jenkins, G.I., Lean, M.E.J. and Crozier, A. (2000) "Occurrence of flavonols in tomatoes and tomato-based products", J. Agric. Food Chem. 48, 2663-2669.
  • Heinonen, I.M., Meyer, A.S. and Frankel, E.N. (1998) "Antioxidant activity of berry phenolics on human lowdensity lipoprotein and liposome oxidation", J. Agric. Food Chem. 46, 4107-4112.
  • Kalt, W., Forney, C.F., Martin, A. and Prior, R.L. (1999) "Antioxidant capacity, Vitamin C, phenolics and anthocyanins after fresh storage of small fruits", J. Agric. Food Chem. 47, 4638-4644.
  • Wang, S. Y. and Lin, H.-S. (2000) "Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage", J. Agric. Food Chem. 48, 140-146.
  • Vinson, J.A., Hao, Y., Su, X. and Zubik, L. (1998) "Phenol antioxidant quantity and quality in foods: vegetables", J. Agric. Food Chem. 46, 3630-3634.
  • Sanoner, P., Guyot, S., Marnet, N., Molle, D. and Drilleau, J.-F.(1999) "Polyphenol profiles of French cider apple varieties (Malus domestica sp.)", J. Agric. Food Chem. 47, 4847-4853.
  • Chang, S., Tan, C., Frankel, E.N. and Barrett, D. (2000) "Lowdensity lipoprotein antioxidant activity of phenolic compounds and polyphenol oxidase activity in selected clingstone peach cultivars", J. Agric. Food Chem. 48, 147-151.
  • Gardner, P.T., White, T.A.C., McPhail, D.B. and Duthie, G.G.(2000) "The relative contributions of Vitamin C, carotenoids and phenolics to the antioxidant potential of fruit juices", Food Chem. 68, 471-474.
  • Prior, R.L., Cap, G., Martin, A., Sofic, E., McEwen, J., O'Brien, C., Lischner, N., Ehlenfeldt, M., Kalt, W., Krewer, G. and Mainland, C.M. (1998) "Antioxidant capacity as influenced by total phenolic and anthocyanin content, maturity, and variety of Vaccinium species", J. Agric. Food Chem. 46, 2686-2693.
  • Kahkonen, M.P., Hopia, A.I., Vuorela, H.J., Rauha, J.-P, Pihlaja, K., Kujala, T.S. and Heinonen, M. (1999) "Antioxidant activity of plants extracts containing phenolic compounds", J. Agric. Food Chem. 47, 3954-3962.
  • Pekkarinen, S.S., Stockmann, H., Schwarz, K., Heinonen, I.M. and Hopia, A.I. (1999) "Antioxidant activity and partitioning of phenolic acids in bulk and emulsified methyl linoleate", J. Agric. Food Chem. 47, 3036-3043.
  • Gerritsen, M.E., Carley, W.W., Ranges, G.E., Shen, C.P., Phan, S.A., Ligon, G.F. and Perry, C.A. (1995) "Flavonoids inhibit cytokine-induced endothelial cell adhesion protein gene expression", Am. J. Pathol. 147, 278-292.
  • Panes, J., Gerritsen, M.E., Anderson, D.C., Miyasaka, M. and Granger, D.M. (1996) "Apigenin inhibits tumor necrosis factor-induced intercellular adhesion molecule-1 upregulation in vivo", Microcirculation 3, 279-286.
  • Soriani, M., Rice-Evans, C.A. and Tyrrell, R.M. (1998) "Modulation of the UVA activation of haem oxygenase, collagenase and cyclooxygenase gene expression by epigallocatechin in human skin cells", FEBS Lett. 439, 253-257.
  • Schroeter, H., Williams, R.J., Matin, R., Iversen, L. and RiceEvans, C.A. (2000) "Phenolic antioxidants attenuate neuronal call death following uptake of oxidized low density lipoprotein", Free Radic. Biol. Med. 29, 1222-1233.
  • Spencer, J.P.E., Schroeter, H., Kuhnle, G., Srai, S.K.S., Tyrrell, R.M., Hahn, U. and Rice-Evans, C. (2001) "Epicatechin and its in vivo metabolite, 3'-O-methyl epicatechin, protect human fibroblasts from oxidative-stress-induced cell death involving caspace-3 activation", Biochem. J. 354, 493-500.
  • Schroeter, H., Spencer, J.P.E., Rice-Evans, C. and Williams, R.J. (2001) "Flavonoids protect neurones from oxidised low-density lipoprotein-induced apoptosis involving JNK, c-jun and caspase-3", Biochem. J., 358, 547-557.

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