Dual role of vitamin C in an oxygen-sensitive system: Discrepancy between DNA damage and dell death

References

• Gutteridge JM, Halliwell B. Free radicals and antioxidants in the year 2000. A historical look to the future. Ann N Y Acad Sci 2000;899:136–147.
   PubMed Web of Science ®Google Scholar
• Halliwell B, Gutteridge JMC. Free Radicals in Biology and Medicine. Oxford: Oxford University Press; 1999.
   Google Scholar
• Harman D. The aging process. Proc Natl Acad Sci USA 1981;78:7124–7128.
   PubMed Web of Science ®Google Scholar
• Ames BN. Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases. Science 1983;221:1256–1264.
   Google Scholar
• Poli G, Parola M. Oxidative damage and fibrogenesis. Free Radic Biol Med 1997;22:287–305.
   PubMed Web of Science ®Google Scholar
• Carney JM, Starke-Reed PE, Oliver CN, Landum RW, Cheng MS, Wu JF, Floyd RA. Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity, and loss in temporal and spatial memory by chronic administration of the spin-trapping compound N-tert-butyl-alpha-phenylnitrone. Proc Natl Acad Sci USA 1991;88:3633–3636.
   PubMed Web of Science ®Google Scholar
• Kong SW, Chae HZ, Seo MS, Kim K, Baines IC, Rhee SG. Mammalian permdredoxin isoforms can reduce hydrogen peroxide generated in response to growth factors and tumor necrosis factor-alpha. J Biol Chem 1998;273:6297–6302.
   PubMedGoogle Scholar
• Block G, Patterson B, Subar A. Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence. Nutr Cancer 1992;18:1–29.
   PubMed Web of Science ®Google Scholar
• Gaziano JM, Manson JE, Buring JE, Hennekens CH. Dietary antioxidants and cardiovascular disease. Ann N Y Acad Sci 1992;669:249–258.
   PubMed Web of Science ®Google Scholar
• Block G. Vitamin C and cancer prevention: the epidemiologic evidence. Am J Chin Nutr 1991;53:2705–2825.
   Google Scholar
• Drake IM, Davies MJ, Mapstone NP, Dixon MF, Schorah CJ, White KL, Chalmers DM, Axon AT. Ascorbic acid may protect against human gastric cancer by scavenging mucosal oxygen radicals. Carcinogenesis 1996;17:559–562.
   PubMed Web of Science ®Google Scholar
• Frei B, England L, Ames BN. Ascorbate is an outstanding antioxidant in human blood plasma. Proc Natl Acad Sci USA 1989;86:6377–6381.
   PubMed Web of Science ®Google Scholar
• Frei B, Forte TM, Ames BN, Cross CE. Gas phase oxidants of cigarette smoke induce lipid peroxidation and changes in lipoprotein properties in human blood plasma. Protective effects of ascorbic acid. Biochem J 1991;277:133–138.
   PubMed Web of Science ®Google Scholar
• Haliwell B. Vitamin C: antioxidant or pro-oxidant in vivo? Free Radic Res 1996;25:439–454.
   PubMedGoogle Scholar
• Sakagami H, Satoh K. Modulating factors of radical intensity and cytotoxic activity of ascorbate (review). Anticancer Res 1997;17:3513–3520.
   PubMed Web of Science ®Google Scholar
• Shamberger RJ. Genetic toxicology of ascorbic acid. Mutat Res 1984;133:135–159.
   PubMed Web of Science ®Google Scholar
• Podmore ID, Griffiths HR, Herbert KE, Mistry N, Mistry P, Lunec J. Vitamin C exhibits pro-oxidant properties. Nature 1998;392:559.
   PubMed Web of Science ®Google Scholar
• Carr A, Frei B. Does vitamin C act as a pro-oxidant under physiological conditions? FASEB J 1999;13:1007–1024.
   PubMed Web of Science ®Google Scholar
• Halliwell B. Vitamin C: poison, prophylactic or panacea? Trends Biochem Sci 1999;24:255–259.
   PubMed Web of Science ®Google Scholar
• Takeuchi T, Nakaya Y, Kato N, Watanabe K, Morimoto K. Induction of oxidative DNA damage in anaerobes. FEBS Lett 1999;450:178–180.
   Google Scholar
• Kasai H. Chemistry-based studies on oxidative DNA damage: formation, repair, and mutagenesis. Free Radic Biol Med 2002;33:450–456.
   PubMed Web of Science ®Google Scholar
• Dizdaroglu M. Oxidative damage to DNA in mammalian chromatin. Mutat Res 1992;275:331–342.
   PubMed Web of Science ®Google Scholar
• Floyd RA. The role of 8-hydroxyguanine in carcinogenesis. Carcinogenesis 1990;11:1447–1450.
   PubMed Web of Science ®Google Scholar
• Nakajima M, Takeuchi T, Morimoto K. Determination of 8-hydroxydeoxyguanosine in human cells under oxygen-free conditions. Carcinogenesis 1996;17: 787–791.
   Google Scholar
• Takeuchi T, Nakajima M, Ohta Y, Mure K, Takeshita T, Morimoto K. Evaluation of 8-hydroxydeoxyguanosine, a typical oxidative DNA damage, in human leukocytes. Carcinogenesis 1994;15:1519–1523.
   PubMed Web of Science ®Google Scholar
• Armitage WJ, Mazur P. Osmotic tolerance of human granulocytes. Am J Physiol 1984;247:C373–C381.
   Google Scholar
• Mishra KP. Cell membrane oxidative damage induced by gamma-radiation and apoptotic sensitivity. J Environ Pathol Toxicol Oncol 2004;23:61–66.
   PubMed Web of Science ®Google Scholar
• Rotman B, Papermaster BW. Membrane properties of living mammalian cells as studied by enzymatic hydrolysis of fluorogenic esters. Proc Natl Acad Sci USA 1966; 55:134–141.
   PubMed Web of Science ®Google Scholar
• Fukunaga K, Yoshida M, Nakazono N. A simple, rapid, highly sensitive and reproducible quantification method for plasma malondialdehyde by high-performance liquid chromato-graphy. Biomed Chromatogr 1998;12:300–303.
   Google Scholar
• Liaudet L, Pacher P, Mabley JG, Virag L, Soriano FG, Hasko G, Szabo C. Activation of poly (ADP-ribose) polymerase-1 is a central mechanism of lipopolysaccharide-induced acute lung inflammation. Am J Respir Grit Care Med 2002; 165:372–377.
   Google Scholar
• Takeuchi T, Kato N, Watanabe K, Morimoto K. Mechanism of oxidative DNA damage induction in a strict anaerobe Prevotella melaninogenica. FEMS Microbiol Lett 2000; 192:133–138.
   PubMedGoogle Scholar
• Halliwell B, Dizdaroglu M. The measurement of oxidative damage to DNA by HPLC and GC/MS techniques. Free Radic Res Commun 1992;16:75–87.
   PubMed Web of Science ®Google Scholar
• Halliwell B, Aruoma CH. DNA damage by oxygen-derived species. Its mechanism and measurement in mammalian systems. FEBS Lett 1991;281:9–19.
   PubMed Web of Science ®Google Scholar
• Shigenaga MK, Ames BN. Assays for 8-hydroxy-2'-deoxygua-nosine: a biomarker of in vivo oxidative DNA damage. Free Radic Biol Med 1991;10:211–216.
   PubMed Web of Science ®Google Scholar
• Halliwell B, Gutteridge JM. Role of free radicals and catalytic metal ions in human disease: an overview. Methods Enzymol 1990;186:1–85.
   PubMed Web of Science ®Google Scholar
• Halliwell B, Gutteridge JM. Oxygen toxicity, oxygen radicals, transition metals and disease. Biochem J 1984;219:1–14.
   PubMed Web of Science ®Google Scholar
• Lynch SR, Cook JD. Interaction of vitamin C and iron. Ann N Y Acad Sci 1980;355:32–44.
   PubMedGoogle Scholar
• Herbert V, Shaw S, Jayatilleke E. Vitamin C-driven free radical generation from iron. J Nutr 1996;126:1213S–1220S.
   Google Scholar
• Drouin R, Rodriguez H, Gao SW, Gebreyes Z, O'Connor TR, Holmquist GP, Akman SA. Cupric ion/ascorbate/hydrogen peroxide-induced DNA damage: DNA-bound copper ion primarily induces base modifications. Free Radic Biol Med 1996;21:261–273.
   Google Scholar
• Hu ML, Shih MK. Ascorbic acid inhibits lipid peroxidation but enhances DNA damage in rat liver nuclei incubated with iron ions. Free Radic Res 1997;26:585–592.
   PubMed Web of Science ®Google Scholar
• Woodmansee AN, Imlay JA. Reduced flavins promote oxidative DNA damage in non-respiring Escherichia coli by delivering electrons to intracellular free iron. J Biol Chem 2002;277:34055–34066.
   PubMedGoogle Scholar
• Srinivasan C, Liba A, Imlay JA, Valentine JS, Gralla EB. Yeast lacking superoxide dismutase(s) show elevated levels of "free iron" as measured by whole cell electron paramagnetic resonance. J Biol Chem 2000;275:29187–29192.
   Google Scholar
• Schafer FQ, Buettner GR. Acidic pH amplifies iron-mediated lipid peroxidation in cells. Free Radic Biol Med 2000; 28:1175–1181.
   PubMed Web of Science ®Google Scholar
• Wills ED. Mechanisms of lipid peroxide formation in animal tissues. Biochem J 1966;99:667–676.
   PubMed Web of Science ®Google Scholar
• Burhans WC, Weinberger M, Marchetti MA, Ramachandran L, D'Urso G, Huberman JA. Apoptosis-like yeast cell death in response to DNA damage and replication defects. Mutat Res 2003;532:227–243.
   Google Scholar
• Norbury CJ, Zhivotovsky B. DNA damage-induced apoptosis. Oncogene 2004;23:2797–2808.
   PubMed Web of Science ®Google Scholar
• Nissen SB, Tjonneland A, Stripp C, Olsen A, Christensen J, Overvad K, Dragsted LO, Thomsen B. Intake of vitamins A, C, and E from diet and supplements and breast cancer in postmenopausal women. Cancer Causes Control 2003;14:695–704.
   PubMed Web of Science ®Google Scholar
• Feskanich D, Willett WC, Hunter DJ, Colditz GA. Dietary intakes of vitamins A, C, and E and risk of melanoma in two cohorts of women. Br J Cancer 2003;88:1381–1387.
   PubMed Web of Science ®Google Scholar
• Epe B, Hegler J, Wild D. Singlet oxygen as an ultimately reactive species in Salmonella typhimurium DNA damage induced by methylene blue/visible light. Carcinogenesis 1989;10:2019–2024.
   Google Scholar
• Dahl TA, Midden WR, Hartman PE. Comparison of killing of gram-negative and gram-positive bacteria by pure singlet oxygen. J Bacteriol 1989;171:2188–2194.
   Google Scholar
• Dahl TA, Midden WR, Hartman PE. Pure exogenous singlet oxygen: nonmutagenicity in bacteria. Mutat Res 1988;201:127–136.
   Google Scholar
• Nakano M, Kambayashi Y, Tatsuzawa H, Komiyama T, Fujimori K. Useful 102 (ldelta g) generator, 3-(4'-methyl-l'-naphthyl)-propionic acid, 1',4'-endoperoxide (NEPO), for dioxygenation of squalence (a skin surface lipid) in an organic solvent and bacterial killing in aqueous medium. FEBS Lett 1998;432: 9–12.
   Google Scholar
• Chamberlain J, Moss SH. Lipid peroxidation and other membrane damage produced in Escherichia coli K1060 by near-UV radiation and deuterium oxide. Photochem Photo-biol 1987;45:625–630.
   PubMed Web of Science ®Google Scholar
• Bartoli GM, Galeotti T. Growth-related lipid peroxidation in tumour microsomal membranes and mitochondria. Biochim Biophys Acta 1979;574:537–541.
   PubMed Web of Science ®Google Scholar
• Bocking T, Barrow KD, Netting AG, Chilcott TC, Coster HG, Hofer M. Effects of singlet oxygen on membrane sterols in the yeast Saccharomyces cerevisiae. Eur J Biochem 2000;267:1607–1618.
   PubMedGoogle Scholar
• Chou PT, Khan AU. L-ascorbic acid quenching of singlet delta molecular oxygen in aqueous media: generalized antioxidant property of vitamin C. Biochem Biophys Res Commun 1983;115:932–937.
   PubMed Web of Science ®Google Scholar
• Bodannes RS, Chan PC. Ascorbic acid as a scavenger of singlet oxygen. FEBS Lett 1979;105:195–196.
   PubMed Web of Science ®Google Scholar
• Singh DP, Kshatriya K. NaCl-induced oxidative damage in the cyanobacterium Anabaena doliolum. Curr Microbiol 2002;44:411–417.
   PubMedGoogle Scholar
• Kawanishi S, Inoue S. Mechanism of DNA cleavage induced by sodium chromate (VI) in the presence of hydrogen peroxide. J Biol Chem 1986;261:5952–5958.
   PubMed Web of Science ®Google Scholar
• Takayama F, Egashira T, Yamanaka Y. Singlet oxygen generation from phosphatidylcholine hydroperoxide in the presence of copper. Life Sci 2001;68:1807–1815.
   Google Scholar
• Tanaka K, Miura T, Umezawa N, Urano Y, Kikuchi K, Higuchi T, Nagano T. Rational design of fluorescein-based fluorescence probes. Mechanism-based design of a maximum fluorescence probe for singlet oxygen. J Am Chem Soc 2001;123:2530–2536.
   Google Scholar
• Hvorup R, Chang AB, Saier Jr, MH. Bioinformatic analyses of the bacterial L-ascorbate phosphotransferase system permease family. J Mol Microbiol Biotechnol 2003; 6:191–205.
   PubMedGoogle Scholar
• Buettner GR, Jurkiewicz BA. Ascorbate free radical as a marker of oxidative stress: an EPR study. Free Radic Biol Med 1993;14:49–55.
   PubMed Web of Science ®Google Scholar
• O'Connor HJ, Schorah CJ, Habibzedah N, Axon AT, Cockel R. Vitamin C in the human stomach: relation to gastric pH, gastroduodenal disease, and possible sources. Gut 1989;30:436–442.
   PubMed Web of Science ®Google Scholar
• Wike-Hooley JI,, Haveman J, Reinhold HS. The relevance of tumour pH to the treatment of malignant disease. Radiother Oncol 1984;2:343–366.
   PubMed Web of Science ®Google Scholar
• Arndt H, Palitzsch KD, Scholmerich J. Leucocyte endothelial cell adhesion in indomethacin induced intestinal inflammation is correlated with faecal pH. Gut 1998;42:380–386.
   Google Scholar