Oxidative Status in Chronic Hepatitis C: The Influence of Antiviral Therapy and Prognostic Value of Serum Hydroperoxide Assay

References

• Poynard, T., Bedossa, P. and Opolon, P. (1997) "Natural history of liver fibrosis progression in patients with chronic hepatitis C", Lancet 349, 825–832.
   PubMed Web of Science ®Google Scholar
• Parola, M. and Rubino, G. (2001) "Oxidative stress-related molecules and liver fibrosis", J. Hepatol. 35, 297–306.
   PubMed Web of Science ®Google Scholar
• Sies, H. (2000) "What is oxidative stress?", In: Keaney, J.F., ed., Oxidative Stress and Vascular Disease (Kluwer Academic Publishers, Boston), pp 1–8.
   Google Scholar
• De Maria, N., Colantoni, A., Fagioli, S., Liu, G.J., Rogers, B.K., Farinati, F., et al. (1996) "Association between reactive oxygen species and disease activity in chronic hepatitis C", Free Radic. Biol. Med. 21, 291–295.
   PubMed Web of Science ®Google Scholar
• Shimoda, R., Nagashima, M., Sakamoto, M., Yamaguchi, N., Hirohashi, S., Yokota, J., et al. (1994) "Increased formation of oxidative DNA damage 8-hydroxydeoxyguanosine in human livers with chronic hepatitis", Cancer Res. 54, 3171–3172.
   PubMed Web of Science ®Google Scholar
• Baron, V. and Muriel, P. (1999) "Role of glutathione, lipid permddation and antioxidants on acute bile-duct obstruction in the rat", Biochim. Biophys. Acta 1472, 173–180.
   PubMed Web of Science ®Google Scholar
• Tsai, L.Y., Lee, K.T. and Liu, T.Z. (1998) "Evidence for accelerated generation of hydroxyl radicals in experimental obstructive jaundice of rats", Free Radic. Biol. Med. 24, 732–737.
   PubMed Web of Science ®Google Scholar
• Bianchi, G., Marchesini, G., Fabbri, A., Ronchi, M., Chianese, R. and Grossi, G. (1997) "Lipopermdde plasma levels in patients with liver cirrhosis", Hepatogastroenterology 44, 784–788.
   PubMedGoogle Scholar
• Lu, S.C. (1999) "Regulation of glutathione synthesis: current concepts and controversies", FASEB J. 13, 1169–1183.
   PubMed Web of Science ®Google Scholar
• Newsome, P.N., Beldon, I., Moussa, Y., Delahooke, T.E., Poulopoulos, G., Hayes, P.C., et al. (2000) "Low serum retinol levels are associated with hepatocellular carcinoma in patients with chronic liver disease", Aliment. Pharmacol. Ther. 14, 1295–1301.
   PubMed Web of Science ®Google Scholar
• Peres, W., Turion, M.J., Collado, P.S., Herrmann, S., Marroni, N. and Gonzàlez-Gallego, J. (2000) "The flavonoid quercetin ameliorates liver damage in rats with biliary obstruction", J. Hepatol. 33, 742–750.
   PubMed Web of Science ®Google Scholar
• Larrea, E., Beloqui, 0., Mutioz-Navas, M.A., Civeira, M.P. and Prieto, J. (1998) "Superoxide dismutase in patients with chronic hepatitis C virus infection", Free Radic. Biol. Med. 24, 1235–1241.
   PubMed Web of Science ®Google Scholar
• Loguercio, C., Tuccillo, C., Caporaso, N., Del Vecchio Blanco, G., Morisco, F., Guerriero, C., et al. (1998) "Determi-nation of plasma alpha-glutathione-S-transferases in patients with HCV-related chronic infection: its significance and possible clinical relevance", Liver 18, 166–172.
   PubMedGoogle Scholar
• Okuda, M., Li, K., Beard, M.R., Showalter, L.A., Scholle, F., Lemon, S.M., et al. (2002) "Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein", Gastroenterology 22, 366–375.
   Google Scholar
• McHutchison, J.G., Gordon, S.C., Schiff, E.R., Shiffman, M.L., Lee, W.M., Rustgi, V.K., et al. (1998) "IFN alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. Hepatitis Interventional Therapy Group", N. Engl. J. Med. 339, 1485–1492.
   PubMed Web of Science ®Google Scholar
• Davis, G.L., Esteban-Mur, R., Rustgi, V., Hoefs, J., Gordon, S.C., Trepo, C., et al. (1998) "IFN alfa-2b alone or in combination with ribavirin for the treatment of relapse of chronic hepatitis C. International Hepatitis Interventional Therapy Group", N. Engl. J. Med. 339, 1493–1499.
   PubMed Web of Science ®Google Scholar
• Farinati, F., Cardin, R., De Maria, N., Della Libera, G., Marafin, C., Lecis, E., et al. (1995) "Iron storage, lipid permddation and glutathione turnover in chronic anti-HCV positive hepatitis", J. Hepatol. 22, 449–456.
   PubMed Web of Science ®Google Scholar
• Mutlu-Turkoglu, U., Ademoglu, E., Turkoglu, S., Badur, S., Uysal, M. and Toker, G. (1997) "The effects of interferon-alpha on serum lipid peroxidation and total thiol content in patients with chronic active hepatitis C", Res. Commun. Mol. Pathol. Pharmacol. 96, 357–361.
   PubMedGoogle Scholar
• De Franceschi, L., Fattovich, G., Turrini, F., Ayi, K., Brugnara, C., Manzato, E, et al. (2000) "Hemolytic anemia induced by ribavirin therapy in patients with chronic hepatitis C virus infection: role of membrane oxidative damage", Hepatology 31, 997–1004.
   PubMed Web of Science ®Google Scholar
• Cesarone, M.R., Belcaro, G., Caratelli, M., Comelli, U., De Sanctis, M.T., Incandela, L., Barsotti, A., Terranova, R. and Nicolaides, A. (1999) "A simple test to monitor oxidative stress", Int. Ang. 18, 127–130.
   PubMed Web of Science ®Google Scholar
• Comelli, U., Terranova, R., Luca, S., Comelli, M. and Alberti, A. (2001) "Bioavailability and antioxidant activity of some food supplements in men and women using the D-Roms test as a marker of oxidative stress", J. Nutr. 131, 3208–3211.
   PubMed Web of Science ®Google Scholar
• Verde, V., Fogliano, V., Ritieni, A., Maiani, G., Morisco, F. and Caporaso, N. (2002) "Use of N,N-dimethyl-p-phenylene-diamine to evaluate the oxidative status of human serum", Free Radic. Res. 36, 869–873.
   PubMed Web of Science ®Google Scholar
• Alberti, A., Bolognini, L., Macciantelli, D. and Carratelli, M. (2000) "The radical cation of N,N-diethyl-para-phenilen-diamine: a possible indicator of oxidative stress in biological samples", Res. Chem. Intermed. 26, 253–267.
   Web of Science ®Google Scholar
• Knodell, R., Ishak, K., Black, W., Chen, T.S., Craig, R., Kaplowits, N., et al. (1981) "Formulation and application of numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis", Hepatology 1, 431–435.
   PubMed Web of Science ®Google Scholar
• Lai, M.M. (2002) "Hepatitis C virus proteins: direct link to hepatic oxidative stress, steatosis, carcinogenesis and more", Gastroenterology 122, 568–571.
   PubMed Web of Science ®Google Scholar
• Jain, S.K., Pemberton, P.W., Smith, A., McMahon, R.F.T., Burrows, P.C., Aboutwerat, A., et al. (2002) "Oxidative stress in chronic hepatitis C: not just a feature of late stage disease", J. Hepatol. 36, 805–811.
   PubMed Web of Science ®Google Scholar
• Conjeevaram, H.S., Everhart, J. and Hoofnagle, J.H. (1995) "Predictors of a sustained beneficial response to interferon alpha therapy in chronic hepatitis C", Hepatology 22, 1326–1329.
   PubMed Web of Science ®Google Scholar
• Vendemmiale, G., Grattagliano, I., Portincasa, P., Serviddio, G., Palasciano, G. and Altomare, E. (2001) "Oxidative stress in symptom-free HCV carriers: relation with ALT flare-up", Fur. J. Clin. Investig. 31, 54–63.
   Web of Science ®Google Scholar
• Loguercio, C., Caporaso, N., Tuccillo, C., Morisco, F., Del Vecchio Blanco, G. and Del Vecchio Blanco, C. (1998) "Alpha-glutathione transferases in HCV-related chronic hepatitis: a new predictive index of response to IFN therapy?", J. Hepatol. 28, 390–395.
   PubMed Web of Science ®Google Scholar
• Sumida, Y., Nakashima, T., Yot, T., Nakajima, Y., Ishikawa, H., Mitsuyoshi, H., et al. (2000) "Serum thioredoxin levels as an indicator of oxidative stress in patients with hepatitis C virus infection", J. Hepatol. 33, 616–622.
   PubMed Web of Science ®Google Scholar
• Barbaro, G., Di Lorenzo, G., Soldini, M., Parrotto, S., Bellomo, G., Belloni, G., et al. (1996) "Hepatic glutathione deficiency in chronic hepatitis C: quantitative evaluation in patients who are HIV positive and HIV negative and correlation with plasmatic and lymphocytic concentration and with activity of the liver disease", Am. J. Gastroenterol. 91, 2569–2573.
   PubMed Web of Science ®Google Scholar
• Beloqui, 0., Prieto, J., Suarez, M., Gil, B., Qian, C.H., Garcia, N., et al. (1993) "N-acetyl cysteine enhances the response to interferon-alpha in chronic hepatitis C: a pilot study", J. Interferon Res. 13, 279–282.
   PubMedGoogle Scholar
• Ideo, G., Bellobuono, A., Tampini, S., Mondazzi, L., Airoldi, A., Benetti, G., et al. (1999) "Antioxidant drugs combined with alpha-interferon in chronic hepatitis C not responsive to alpha-interferon alone: a randomised, multi-centre study", Fur. J. Gastroenterol. Hepatol. 11, 1203–1207.
   Google Scholar
• Look, M.P., Gerard, A., Rao, G.S., Sudhop, T., Fisher, H.P., Sauerbruch, T., et al. (1999) "Interferon / antimddant combi-nation therapy for chronic hepatitis C: a controlled pilot trial", Antiviral Res. 43, 113–122.
   PubMed Web of Science ®Google Scholar