Advanced search
Publication Cover
Free Radical Research Volume 38, 2004 - Issue 6
Submit an article Journal homepage
52
Views
36
CrossRef citations to date
0
Altmetric
Original Article

Do Mitochondria make Nitric Oxide? No?

Yvonne Mei Sian Tay Department of Biochemistry, Faculty of Medicine, National University of Singapore, MD 7 #, 8 Medical Drive, 117597, Singapore, SingaporeCorrespondence[email protected]
,
Kok Seong Lim Department of Biochemistry, Faculty of Medicine, National University of Singapore, MD 7 #, 8 Medical Drive, 117597, Singapore, Singapore
,
Fwu-Shan Sheu Department of Biological Sciences, Faculty of Science, National University of Singapore, 14 Science Drive 4, 117543, Singapore, Singapore
,
Andrew Jenner Department of Biochemistry, Faculty of Medicine, National University of Singapore, MD 7 #, 8 Medical Drive, 117597, Singapore, Singapore
,
Matthew Whiteman Department of Biochemistry, Faculty of Medicine, National University of Singapore, MD 7 #, 8 Medical Drive, 117597, Singapore, Singapore
,
Kim Ping Wong Department of Biochemistry, Faculty of Medicine, National University of Singapore, MD 7 #, 8 Medical Drive, 117597, Singapore, Singapore
&
Barry Halliwell Department of Biochemistry, Faculty of Medicine, National University of Singapore, MD 7 #, 8 Medical Drive, 117597, Singapore, Singapore
 show all
Pages 591-599 | Received 21 Jan 2004, Published online: 07 Jul 2009

References

  • Bredt, D.S. (1999) "Endogenous nitric oxide synthesis: biological functions and pathophysiology", Free Radic. Res. 31, 577–596.
  • Alderton, W.K., Cooper, CT. and Knowles, R.G. (2001) "Nitric oxide synthases: structure, function and inhibition", Biochem. J. 357, 593–615.
  • Bates, T.E., Loesch, A., Burnstock, G. and Clark, J.B. (1996) "Mitochondrial nitric oxide synthase: a ubiquitous regulator of oxidative phosphorylation?", Biochem. Biophys. Res. Com-mun. 218, 40–44.
  • Ghafourifar, P. and Richter, C. (1997) "Nitric oxide synthase activity in mitochondria", FEBS Lett. 418, 291–296.
  • Ghafourifar, P. and Richter, C. (1999) "Mitochondrial nitric oxide synthase regulates mitochondrial matrix pH", Biol. Chem. 380, 1025–1028.
  • Ghafourifar, P., Schenk, U., Klein, S.D. and Richter, C. (1999) "Mitochondrial nitric oxide synthase stimulation causes cytochrome c release from isolated mitochondria", J. Biol. Chem. 274, 31185–31188.
  • Giulivi, C. (1998) "Functional implications of nitric oxide produced by mitochondria in mitochondrial metabolism", Biochem. J. 332, 673–679.
  • Giulivi, C. (2003) "Characterization and function of mitochon-drial nitric-oxide synthase", Free Radic. Biol. Med. 34,397–408.
  • Guilivi, C., Poderoso, J.J. and Boveris, A. (1998) "Production of nitric oxide by mitochondria", J. Biol. Chem. 273, 11038–11043.
  • Elfering, S.L., Sarkela, T.M. and Giulivi, C. (2002) "Bio-chemistry of mitochondrial nitric-oxide synthase", J. Biol. Chem. 277, 38079–38086.
  • Lacza, Z., Snipes, J.A., Zhang, J., Horvith, EM., Figueroa, J.P., Szabó, C. and Busija, D.W. (2003) "Mitochondrial nitric oxide synthase is not eNOS, nNOS or iNOS", Free Radic. Biol. Med. 35, 1217–1228.
  • Brookes, P.S. (2004) "Mitochondrial nitric oxide synthase", Mitochondrion 3, 187–204.
  • Tang, J., Faustman, C., Lee, S. and Hoagland, T.A. (2003) "Effect of glutathione on oxymyoglobin oxidation", J. Agric. Food Chem. 51, 1691–1695.
  • Miao, H.H., Ye, J.S., Wong, S.L.Y., Wang, B.X., Li, X.Y. and Sheu, ES. (2000) "Oxidative modification of neurogranin by nitric oxide: an amperometric study", Bioelectrochemistry 51,163–173.
  • Brookes, P.S., Levonen, A.L., Shiva, S. and Darley-Usmar, V.M. (2002) "Mitochondria: regulators of signal transduction by reactive oxygen and nitrogen species", Free Radic. Biol. Med. 33, 755–764.
  • Brookes, P.S., Kraus, D.W., Shiva, S., Doeller, J.E., Barone, M.C., Patel, R.P., Lancaster, J.R., Jr. and Darley-Usmar, V.M. (2002) "Control of mitochondrial respiration by NO, effects of low oxygen and respiratory state", J. Biol. Chem. 278, 31603–31609.
  • Mital, S., Loke, K.E., Addonizio, L.J., Oz, M.C. and Hintze, T.H. (2000) "Left ventricular assist device implantation augments nitric oxide dependent control of mitochondrial respiration in failing human hearts", J. Am. Coll. Cardiol. 36, 1897–1902.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.