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Original Article

Involvement of Ceramide in the Mechanism of Cr(VI)-induced Apoptosis of CHO Cells

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Pages 613-621 | Received 10 Nov 2003, Published online: 07 Jul 2009

References

  • Stohs, S.J., Bagchi, D., Hassoun, E. and Bagchi, M. (2000) "Oxidative mechanisms in the toxicity of chromium and cadmium ions", J. Environ. Pathol. Toxicol. Oncol. 19, 201–213.
  • Rossi, S.C., Gorman, N. and Wetterhahn, K.E. (1988) "Mitochondrial reduction of the carcinogen chromate: formation of chromium (V)", Chem. Res. Toxicol. 1, 101–107.
  • Wetterhahn, K.E., Hamilton, J.W., Aiyar, J., Borges, K.M. and Floyd, R. (1989) "Mechanism of chromium (VI) carcinogen-esis. Reactive intermediates and effect on gene expression", Biol. Trace Elem. Res. 21, 405–411.
  • Klein, C.B., Frenkel, K. and Costa, M. (1991) "The role of oxidative processes in metal carcinogenesis", Chem. Res. Toxicol. 4, 592–604.
  • Rossi, S.C. and Wetterhahn, K.E. (1989) "Chromium(V) is produced upon reduction of chromate by mitochondrial electron transport chain complexes", Carcinogenesis 10, 913–920.
  • Ryberg, D. and Alexander, J. (1990) "Mechanisms of chromium toxicity in mitochondria", Chem. Biol. Interact. 75, 141–151.
  • Shi, X., Chiu, A., Chen, C.T., Halliwell, B., Castranova, V. and Vallyathan, V. (1999) "Reduction of chromium (VI) and its relationship to carcinogenesis", J. Toxicol. Environ. Health Part B Crit. Rev. 2, 87–104.
  • Ye, J., Wang, S., Leonard, S.S., Sun, Y, Butterworth, L., Antonini, J., Ding, M., Rojanasakul, Y., Vallyathan, V, Castranova, V. and Shi, X. (1999) "Role of reactive oxygen species and p53 in chromium(VI)-induced apoptosis", J. Biol. Chem. 274, 34974–34980.
  • Pritchard, D.E., Singh, J., Carlisle, D.L. and Patierno, S.R. (2000) "Cyclosporin A inhibits chromium (VI)-induced apoptosis and mitochondrial cytochrome c release and restores clonogenic survival in CHO cells", Carcinogenesis 21, 2027–2033.
  • Leonard, S.S., Vallyathan, V, Castranova, V. and Shi, X. (2002) "Generation of reactive oxygen species in the enzymatic reduction of PbCr04 and related DNA damage", Mol. Cell. Biochem. 234,235, 309–315.
  • Kawanishi, S., Inoue, S. and Sano, S. (1986) "Mechanism of DNA cleavage induced by sodium chromate(VI) in the presence of hydrogen peroxide", J. Biol. Chem. 261,5952–5958.
  • Green, D.R. and Reed, J.C. (1998) "Mitochondria and apoptosis", Science 281, 1309–1312.
  • Nishikimi, A., Kira, Y., Kasahara, E., Sato, E.F., Kanno, T., Utsumi, K. and Inoue, M. (2001) "Tributyltin interacts with mitochondria and induces cytochrome c release", Biochem.J. 356, 621–626.
  • Petronilli, V, Penzo, D., Scorrano, L., Bernardi, P. and Di Lisa, F. (2001) "The mitochondrial permeability transition, release of cytochrome c and cell death. Correlation with the duration of pore openings in situ", J. Biol. Chem. 276, 12030–12034.
  • Perry, D.K. (1999) "Ceramide and apoptosis", Biochem. Soc. Symp. 27, 399–404.
  • Richter, C. and Ghafourifar, P (1999) "Ceramide induces cytochrome c release from isolated mitochondria", Biochem. Soc. Symp. 66, 27–31.
  • Andrieu-Abadie, N., Gouaze, V, Salvayre, R. and Levade, T. (2001) "Ceramide in apoptosis signaling: relationship with oxidative stress", Free. Radic. Biol. Med. 31, 717–728.
  • Rytomaa, M., Lehmann, K. and Downward, J. (2000) "Matrix detachment induces caspase-dependent cytochrome c release from mitochondria: inhibition by PKB/Akt but not Rd signalling", Oncogene 19, 4461–4468.
  • Kim, D.S., Kim, S.Y., Moon, S.J., Chung, J.H., Kim, K.H., Cho, K.H. and Park, K.C. (2001) "Ceramide inhibits cell proliferation through Akt/PKB inactivation and decreases melanin synthesis in Mel-Ab cells", Pigm. Cell Res. 14, 110–115.
  • Zhang, L., Himi, T., Morita, I. and Murota, S. (2001) "Inhibition of phosphatidylinosito1-3 kinase/Akt or mitogen-activated protein kinase signaling sensitizes endothelial cells to TNF-alpha cytotoxicity", Cell Death Differ. 8, 528–536.
  • Zinda, M.J., Vlahos, C.J. and Lai, M.T. (2001) "Ceramide induces the dephosphorylation and inhibition of constitu-tively activated Akt in 1' EN negative U87 mg cells", Biochem. Biophys. Res. Commun. 280, 1107–1115.
  • Bourbon, N.A., Sandirasegarane, L. and Kester, M. (2002) "Ceramide-induced inhibition of Akt is mediated through protein kinase Czeta: implications for growth arrest", J. Biol. Chem. 277, 3286–3292.
  • Blankenship, L.J., Manning, F.C., Orenstein, J.M. and Patierno, S.R. (1994) "Apoptosis is the mode of cell death caused by carcinogenic chromium", Toxicol. Appl. Pharmacol. 126, 75–83.
  • Manning, F.C., Blankenship, L.J., Wise, J.P., Xu, J., Bridge-water, L.C. and Patierno, S.R. (1994) "Induction of inter-nudeosomal DNA fragmentation by carcinogenic chromate: relationship to DNA damage, genotoxicity, and inhibition of macromolecular synthesis", Environ. Health. Perspect 102\(Suppl. 3), 159–167.
  • Shimada, H., Shiao, Y.H., Shibata, M. and Waalkes, M.P. (1998) "Cadmium suppresses apoptosis induced by chromium", J. Toxicol. Environ. Health 54, 159–168.
  • Yuan, C., Kadiiska, M., Achanzar, W.E., Mason, RT. and Waalkes, M.P. (2000) "Possible role of caspase-3 inhibition in cadmium-induced blockage of apoptosis", Toxicol. Appl. Pharmacol. 164, 321–329.
  • Yabuki, M., Inai, Y., Yoshioka, T., Hamazaki, K., Yasuda, T., Inoue, M. and Utsumi, K. (1997) "Oxygen-dependent fragmentation of cellular DNA by nitric oxide", Free Rad. Res. 26, 245–255.
  • Arita, K., Utsumi, T., Kato, A., Kanno, T., Kobuchi, H., Inoue, M., Akiyama, J. and Utsumi, K. (2000) "Mechanism of Dibucaine-Induced Apoptosis in Promyelocytic Leukemia Cells (HL-60)", Biochem. Pharmacol. 60, 905–915.
  • Yabuki, M., Kariya, S., Inai, Y., Hamazaki, K., Yoshioka, T., Yasuda, T., Horton, A.A. and Utsumi, K. (1997) "Molecular mechanisms of apoptosis in HL-60 cells induced by a nitric oxide-releasing compound", Free Rad. Res. 27, 325–335.
  • Kariya, S., Ogawa, Y, Yoshida, S., Yabuki, M., Imajo, Y. and Utsumi, K. (1999) "X-irradiation enhances the expression of Bc1-2 in HL-60 cells: The resulting effects on apoptosis and radiosensitivity", Int. J. Mol. Med. 3, 145–152.
  • Bradford, M.M. (1976) "A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding", Anal. Biochem. 72,248–254.
  • Salvioli, S., Ardizzoni, A., Franceschi, C. and Cossarizza, A. (1997) "JC-1, but not Di0C6(3) or rhodamine 123, is a reliable fluorescent probe to assess delta psi changes in intact cells: implications for studies on mitochondrial functionality during apoptosis", FEBS Lett. 411, 77–82.
  • Wiegmann, K., Schutze, S., Machleidt, T., Witte, D. and Kronke, M. (1994) "Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling", Cell 78, 1005–1015.
  • Okazaki, T., Bielawska, A., Bell, R.M. and Hannun, Y.A. (1990) "Role of ceramide as a lipid mediator of 1 alpha,25-dihydroxyvitamin D3-induced HL-60 cell differen-tiation", J. Biol. Chem. 265, 15823–15831.
  • Bligh, E.G. and Dyer, W.J. (1959) "A rapid method of total lipid extraction and purification", Can. J. Biochem. Physiol. 37, 911–917.
  • Zoratti, M. and Szabo, I. (1995) "The mitochondrial permeability transition", Biochim. Biophys. Acta 1241, 139–176.
  • Malisan, F. and Testi, R. (1999) "Lipid signaling in CD95-mediated apoptosis", FEBS Lett. 452, 100–103.
  • Cole11, A., Morales, A., Fernandez-Checa, J.C. and Garcia-Ruiz, C. (2002) "Ceramide generated by acidic sphingo-myelinase contributes to tumor necrosis factor-alpha-mediated apoptosis in human colon HT-29 cells through glyco-sphingolipids formation.Possible role of ganglioside GD3", FEBS Lett. 526, 135–141.
  • Sable, C.L., Filippa, N., Hemmings, B. and Obberghen, E.V. (1997) "cAMP stimulate protein kinase B in a Wortmannin-insensitive manner", FEBS Lett. 409, 253–257.
  • Li, J., Yang, S. and Billiar, T.R. (2000) "Cyclic nucleotides suppress tumor necrosis factor-amediated apoptosis by inhibiting caspase activation and cytochrome c release in primary hepatocytes via a mechanism independent of Akt activation", J. Biol. Chem. 275, 13026–13034.
  • Inoki, Y, Miura, T., Kajimoto, T., Kawase, M., Kawase, Y., Yoshida, Y., Tsuji, S., Kinouchi, T., Endo, H., Kagawa, Y. and Hamamoto, T. (2000) "Ganglioside GD3 and its mimetics induce cytochrome c release from mitochondria", Biochem. Biophys. Res. Commun. 276, 1210–1216.
  • Schubert, K.M., Scheid, M.P. and Duronio, V. (2000) "Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473", J. Biol. Chem. 275, 13330–13335.
  • Rokhlin, 0.W., Guseva, N.V., Tagiyev, A.F., Glover, R.A. and Cohen, M.B. (2002) "Caspase-8 activation is necessary but not sufficient for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in the prostatic carcinoma cell line LNCaP", Prostate 52, 1–11.
  • Singh, R., Pervin, S. and Chaudhuri, G. (2002) "Caspase-8-mediated Bid cleavage and release of mitochondrial cytochrome c during Nomega-hydroxy-L-arginine-induced apoptosis in MDA-MB-468 cells.Antagonistic effects of L-ornithine", J. Biol. Chem. 277, 37630–37636.
  • Balamurugan, K., Rajaram, R., Ramasami, T. and Narayanan, S. (2002) "Chromium (IL)-induced apoptosis of lymphocytes: death decision by ROS and Src-family tyrosine kinases", Free Radic. Biol. Med. 33, 1622–1640.
  • Komatsu, M., Takahashi, T., Abe, T., Takahashi, I., Ida, H. and Takada, G. (2001) "Evidence for the association of ultraviolet-C and H(2)0(2)-induced apoptosis with acid sphingomyelinase activation", Biochim. Biophys. Acta. 1533, 47–54.
  • Martin, D., Salinas, M., Fujita, N., Tsuruo, T. and Cuadrado, A. (2002) "Ceramide and reactive oxygen species generated by H202 induce caspase-3-independent degradation of Akt/protein kinase B", J. Biol. Chem. 277, 42943–42952.
  • Garcia-Ruiz, C., Mari, M., Morales, A., Colell, A., Ardite, E. and Fernandez-Checa, J.C. (2000) "Human placenta sphingo-myelinase, an exogenous acidic pH-optimum sphingomyeli-nase, induces oxidative stress, glutathione depletion, and apoptosis in rat hepatocytes", Hepatology 32, 56–65.
  • Corda, S., Laplace, C., Vicaut, E. and Duranteau, J. (2001) "Rapid reactive oxygen species production by mitochondria in endothelial cells exposed to tumor necrosis factor-alpha is mediated by ceramide", Am. J. Respir. Cell Mol. Biol. 24, 762–768.

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