Helicobacter hepaticus Dps protein plays an important role in protecting DNA from oxidative damage

References

• Ward JM, Fox JG, Anver MR, Haines DC, George CV, Collins MJ, Jr, Gorelick PL, Nagashima K, Gonda MA, Gilden RV, et al. Chronic active hepatitis and associated liver tumors in mice caused by a persistent bacterial infection with a novel Helicobacter species. J Natl Cancer Inst 1994; 86(16)1222–1227
   PubMedGoogle Scholar
• Fox JG, Dewhirst FE, Tully JG, Paster BJ, Yan L, Taylor NS, Collins MJ, Jr, Gorelick PL, Ward JM. Helicobacter hepaticus sp. nov., a microaerophilic bacterium isolated from livers and intestinal mucosal scrapings from mice. J Clin Microbiol 1994; 32(5)1238–1245
   PubMed Web of Science ®Google Scholar
• Burich A, Hershberg R, Waggie K, Zeng W, Brabb T, Westrich G, Viney JL, Maggio-Price L. Helicobacter-induced inflammatory bowel disease in IL-10- and T cell-deficient mice. Am J Physiol Gastrointest Liver Physiol 2001; 281(3)G764–G778
   PubMed Web of Science ®Google Scholar
• Chin EY, Dangler CA, Fox JG, Schauer DB. Helicobacter hepaticus infection triggers inflammatory bowel disease in T cell receptor alpha beta mutant mice. Comp Med 2000; 50(6)586–594
   PubMedGoogle Scholar
• Maggio-Price L, Bielefeldt-Ohmann H, Treuting P, Iritani BM, Zeng W, Nicks A, Tsang M, Shows D, Morrissey P, Viney JL. Dual infection with Helicobacter bilis and Helicobacter hepaticus in p-glycoprotein-deficient mdr1a-/-mice results in colitis that progresses to dysplasia. Am J Pathol 2005; 166(6)1793–1806
   PubMed Web of Science ®Google Scholar
• Erdman SE, Poutahidis T, Tomczak M, Rogers AB, Cormier K, Plank B, Horwitz BH, Fox JG. CD4+ CD25+ regulatory T lymphocytes inhibit microbially induced colon cancer in Rag2-deficient mice. Am J Pathol 2003; 162(2)691–702
   PubMed Web of Science ®Google Scholar
• Fraser CM, Casjens S, Huang WM, Sutton GG, Clayton R, Lathigra R, White O, Ketchum KA, Dodson R, Hickey EK, et al. Genomic sequence of a Lyme disease Spirochaete, Borrelia burgdorferi. Nature 1997; 390(6660)580–586
   PubMedGoogle Scholar
• Rogers AB, Fox JG. Inflammation and cancer. I. Rodent models of infectious gastrointestinal and liver cancer. Am J Physiol Gastrointest Liver Physiol 2004; 286(3)G361–G366
   PubMed Web of Science ®Google Scholar
• Suerbaum S, Josenhans C, Sterzenbach T, Drescher B, Brandt P, Bell M, Droge M, Fartmann B, Fischer HP, Ge Z, et al. The complete genome sequence of the carcinogenic bacterium Helicobacter hepaticus. Proc Natl Acad Sci USA 2003; 100(13)7901–7906
   PubMed Web of Science ®Google Scholar
• Davies GR, Banatvala N, Collins CE, Sheaff MT, Abdi Y, Clements L, Rampton DS. Relationship between infective load of Helicobacter pylori and reactive oxygen metabolite production in antral mucosa. Scand J Gastroenterol 1994; 29(5)419–424
   PubMed Web of Science ®Google Scholar
• Burdon RH. Superoxide and hydrogen peroxide in relation to mammalian cell proliferation. Free Radic Biol Med 1995; 18(4)775–794
   PubMed Web of Science ®Google Scholar
• Storz G, Imlay JA. Oxidative stress. Curr Opin Microbiol 1999; 2(2)188–194
   PubMed Web of Science ®Google Scholar
• Zhang QM, Takemoto T, Mito S, Yonei S. Induction of repair capacity for oxidatively damaged DNA as a component of peroxide stress response in Escherichia coli. J Radiat Res 1996; 37(3)171–176, Tokyo
   PubMedGoogle Scholar
• Mehta NS, Benoit S, Mysore JV, Sousa RS, Maier RJ. Helicobacter hepaticus hydrogenase mutants are deficient in hydrogen-supported amino acid uptake and in causing liver lesions in A/J mice. Infect Immun 2005; 73(9)5311–5318
   PubMedGoogle Scholar
• Ge Z, Feng Y, Whary MT, Nambiar PR, Xu S, Ng V, Taylor NS, Fox JG. Cytolethal distending toxin is essential for Helicobacter hepaticus colonization in outbreed Swiss Webster mice. Infect Immun 2005; 73(6)3559–3567
   PubMed Web of Science ®Google Scholar
• Martinez A, Kolter R. Protection of DNA during oxidative stress by the nonspecific DNA-binding protein Dps. J Bacteriol 1997; 179(16)5188–5194
   PubMed Web of Science ®Google Scholar
• Altuvia S, Almiron M, Huisman G, Kolter R, Storz G. The dps promoter is activated by OxyR during growth and by IHF and sigma S in stationary phase. Mol Microbiol 1994; 13(2)265–272
   PubMed Web of Science ®Google Scholar
• Grant RA, Filman DJ, Finkel SE, Kolter R, Hogle JM. The crystal structure of Dps, a ferritin homology that binds and protects DNA. Nat Struct Biol 1998; 5(4)294–303
   PubMedGoogle Scholar
• Wolf SG, Frenkiel D, Arad T, Finkel SE, Kolter R, Minsky A. DNA protection by stress-induced biocrystallization. Nature 1999; 400(6739)83–85
   PubMed Web of Science ®Google Scholar
• Buda F, Ensing B, Gribnau MC, Baerends EJ. O2 evolution in the Fenton reaction. Chemistry 2003; 9(14)3436–3444
   PubMedGoogle Scholar
• Bozzi M, Mignogna G, Stefanini S, Barra D, Longhi C, Valenti P, Chiancone E. A novel non-heme iron-binding ferritin related to the DNA-binding proteins of the Dps family in Listeria innocua. J Biol Chem 1997; 272(6)3259–3265
   PubMedGoogle Scholar
• Yamamoto Y, Fukui K, Koujin N, Ohya H, Kimura K, Kamio Y. Regulation of the intracellular free iron pool by Dpr provides oxygen tolerance to Streptococcus mutans. J Bacteriol 2004; 186(18)5997–6002
   PubMedGoogle Scholar
• Gupta S, Chatterji D. Bimodal protection of DNA by Mycobacterium smegmatis DNA-binding protein from stationary phase cells. J Biol Chem 2003; 278(7)5235–5241
   PubMedGoogle Scholar
• Ueshima J, Shoji M, Ratnayake DB, Abe K, Yoshida S, Yamamoto K, Nakayama K. Purification, gene cloning, gene expression and mutants of Dps from the obligate anaerobe Porphyromonas gingivalis. Infect Immun 2003; 71(3)1170–1178
   PubMedGoogle Scholar
• Tonello F, Dundon WG, Satin B, Molinari M, Tognon G, Grandi G, Del Giudice G, Rappuoli R, Montecucco C. The Helicobacter pylori neutrophil-activating protein is an iron-binding protein with dodecameric structure. Mol Microbiol 1999; 34(2)238–246
   PubMedGoogle Scholar
• Ishikawa T, Mizunoe Y, Kawabata S, Takade A, Harada M, Wai SN, Yoshida S. The iron-binding protein Dps confers hydrogen peroxide stress resistance to Campylobacter jejuni. J Bacteriol 2003; 185(3)1010–1017
   PubMedGoogle Scholar
• Andrews SC. Iron storage in bacteria. Adv Microb Physiol 1998; 40: 281–351
   PubMed Web of Science ®Google Scholar
• Ceci P, Ilari A, Falvo E, Chiancone E. The Dps protein of Agrobacterium tumefaciens does not bind to DNA but protects it toward oxidative cleavage: X-ray crystal structure, iron binding and hydroxyl-radical scavenging properties. J Biol Chem 2003; 278(22)20319–20326
   PubMed Web of Science ®Google Scholar
• Ceci P, Cellai S, Falvo E, Rivetti C, Rossi GL, Chiancone E. DNA condensation and self-aggregation of Escherichia coli Dps are coupled phenomena related to the properties of the N-terminus. Nucleic Acids Res 2004; 32(19)5935–5944
   PubMedGoogle Scholar
• Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc Natl Acad Sci USA 1979; 76(9)4350–4354
   PubMed Web of Science ®Google Scholar
• Zirkle RE, Krieg NR. Development of a method based on alkaline gel electrophoresis for estimation of oxidative damage to DNA in Escherichia coli. J Appl Bacteriol 1996; 81(2)133–138
   PubMedGoogle Scholar
• Chen SK, Tsai MH, Hwang JJ, Chang WP. Determination of 8-oxoguanine in individual cell nucleus of gamma-irradiated mammalian cells. Radiat Res 2001; 155(6)832–836
   PubMedGoogle Scholar
• Yamamoto Y, Poole LB, Hantgan RR, Kamio Y. An iron-binding protein, Dpr, from Streptococcus mutans prevents iron-dependent hydroxyl radical formation in vitro. J Bacteriol 2002; 184(11)2931–2939
   PubMed Web of Science ®Google Scholar
• Almiron M, Link AJ, Furlong D, Kolter R. A novel DNA-binding protein with regulatory and protective roles in starved Escherichia coli. Genes Dev 1992; 6(12B)2646–2654
   PubMed Web of Science ®Google Scholar
• Wang Y, Taylor DE. Chloramphenicol resistance in Campylobacter coli: Nucleotide sequence, expression and cloning vector construction. Gene 1990; 94(1)23–28
   PubMedGoogle Scholar
• Chung MC. A specific iron stain for iron-binding proteins in polyacrylamide gels: Application to transferrin and lactoferrin. Anal Biochem 1985; 148(2)498–502
   PubMedGoogle Scholar
• Bacher A, Eberhardt S, Fischer M, Kis K, Richter G. Biosynthesis of vitamin B2 (riboflavin). Annu Rev Nutr 2000; 20: 153–167
   PubMed Web of Science ®Google Scholar
• Chen L, Helmann JD. Bacillus subtilis MrgA is a Dps(PexB) homologue: Evidence for metalloregulation of an oxidative-stress gene. Mol Microbiol 1995; 18(2)295–300
   PubMedGoogle Scholar
• Zhao G, Ceci P, Ilari A, Giangiacomo L, Laue TM, Chiancone E, Chasteen ND. Iron and hydrogen peroxide detoxification properties of DNA-binding protein from starved cells. A ferritin-like DNA-binding protein of Escherichia coli. J Biol Chem 2002; 277(31)27689–27696
   PubMed Web of Science ®Google Scholar
• Stefanini S, Cavallo S, Montagnini B, Chiancone E. Incorporation of iron by the unusual dodecameric ferritin from Listeria innocua. Biochem J 1999; 338(Pt 1)71–75
   PubMedGoogle Scholar
• Ilari A, Stefanini S, Chiancone E, Tsernoglou D. The dodecameric ferritin from Listeria innocua contains a novel intersubunit iron-binding site. Nat Struct Biol 2000; 7(1)38–43
   PubMedGoogle Scholar
• Stillman TJ, Upadhyay M, Norte VA, Sedelnikova SE, Carradus M, Tzokov S, Bullough PA, Shearman CA, Gasson MJ, Williams CH, et al. The crystal structures of Lactococcus lactis MG1363 Dps proteins reveal the presence of an N-terminal helix that is required for DNA binding. Mol Microbiol 2005; 57(4)1101–1112
   PubMedGoogle Scholar
• Cooksley C, Jenks PJ, Green A, Cockayne A, Logan RP, Hardie KR. NapA protects Helicobacter pylori from oxidative stress damage, and its production is influenced by the ferric uptake regulator. J Med Microbiol 2003; 52(Pt 6)461–469
   PubMedGoogle Scholar
• Olczak AA, Olson JW, Maier RJ. Oxidative-stress resistance mutants of Helicobacter pylori. J Bacteriol 2002; 184(12)3186–3193
   PubMedGoogle Scholar