Peroxynitrite as an alternative donor of oxygen in HIF-1α proline hydroxylation under low oxygen availability

References

• Semenza GL. HIF-1 and tumor progression: Pathophysiology and therapeutics. Trends Mol Med 2002; 8: S62–S67
   PubMed Web of Science ®Google Scholar
• Semenza GL. HIF-1 and mechanisms of hypoxia sensing. Curr Opin Cell Biol 2001; 13: 167–171
   PubMed Web of Science ®Google Scholar
• Huang LE, Arany Z, Livingston DM, Bunn HF. Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its α subunit. J Biol Chem 1996; 271: 32253–32259
   PubMed Web of Science ®Google Scholar
• Huang LE, Gu J, Schau M, Bunn HF. Regulation of hypoxia-inducible factor 1α is mediated by an O2-dependent degradation domain via the ubiquitin–proteasome pathway. Proc Natl Acad Sci USA 1998; 95: 7987–7992
   PubMed Web of Science ®Google Scholar
• Kallio PJ, Wilson WJ, O'Brien S, Makino Y, Poellinger L. Regulation of hypoxia-inducible factor 1α by the ubiquitin–proteasome pathway. J Biol Chem 2000; 274: 6519–6525
   Google Scholar
• Maxwell PH, Wiesener MS, Chang GW, Clifford SC, Vaux EC, Cockman ME, Wykoff CC, Pugh CW, Maher ER, Ratcliffe PJ. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 1999; 399: 271–275
   PubMed Web of Science ®Google Scholar
• Tanimoto K, Makino Y, Pereira T, Poellinger L. Mechanism of regulation of the hypoxia-inducible factor-1α by the von Hippel–Lindau tumor suppressor protein. EMBO J 2000; 19: 4298–4309
   PubMed Web of Science ®Google Scholar
• Epstein AC, Gleadle JM, McNeill LA, Hewitson KS, O'Rourke J, Mole DR, Mukherji M, Metzen E, Wilson MI, Dhanda A, Tian YM, Masson N, Hamilton D, Jaakkola LP, Barstead R, Hodgkin J, Maxwell PH, Pugh CW, Schofield CJ, Ratcliffe PJC. Elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell 2001; 107: 43–54
   PubMed Web of Science ®Google Scholar
• Ivan M, Kondo K, Yang H, Kim W, Valiando J, Ohh M, Salic A, Asara JM, Lane WS, Kaelin WG, Jr. HIF-1α targeted for VHL-mediated destruction by proline hydroxylation: Implications for O2 sensing. Science 2001; 292: 464–468
   PubMed Web of Science ®Google Scholar
• Goldberg MA, Dunning SP, Bunn HF. Regulation of the erythropoietin gene: Evidence that the oxygen sensor is a heme protein. Science 1998; 242: 1412–1415
   Google Scholar
• Quintero M, Brennan P, Thomas GJ, Moncada S. Nitric oxide is a factor in the stabilization of hypoxia-inducible factor-1α in cancer: Role of free radical formation. Cancer Res 2006; 66: 770–774
   PubMed Web of Science ®Google Scholar
• Sumbayev VV, Budde A, Zhou J, Brüne B. HIF-1α protein as a target for S-nitrosation. FEBS Lett 2003; 535: 106–112
   PubMed Web of Science ®Google Scholar
• Yasinska IM, Sumbayev VV. S-nitrossation of Cys-800 of HIF-1α protein activates its interaction with p300 and stimulates its transcriptional activity. FEBS Lett 2003; 549: 105–109
   PubMed Web of Science ®Google Scholar
• Metzen E, Zhou J, Jelkmann W, Fandrey J, Brüne B. Nitric oxide impairs normoxic degradation of HIF-1α by inhibition of prolyl hydroxylases. Mol Biol Cell 2003; 14: 3470–3481
   PubMed Web of Science ®Google Scholar
• Sumbayev VV, Yasinska IM. Regulation of MAP kinase-dependent apoptotic pathway: Implication of reactive oxygen and nitrogen species. Arch Biochem Biophys 2005; 436: 406–412
   PubMed Web of Science ®Google Scholar
• Huang EL, Willmore GW, Gu J, Goldberg MA, Bunn HF. Inhibition of hypoxia-inducible factor 1 activation by carbon monoxide and nitric oxide. Implications for oxygen sensing and signalling. J Biol Chem 1999; 274: 9038–9044
   PubMed Web of Science ®Google Scholar
• Agani FH, Puchowicz MJ, Chavez C, Pichiule P, LaManna J. Role of nitric oxide in the regulation of HIF-1α expression during hypoxia. Am J Physiol Cell Physiol 2002; 283: C178–C186
   PubMed Web of Science ®Google Scholar
• Sogawa K, Numayama-Tsuruta K, Ema M, Abe M, Abe H, Fujii-Kuriyama Y. Inhibition of hypoxia-inducible factor 1 activity by nitric oxide donors in hypoxia. Proc Natl Acad Sci USA 1998; 95: 7368–7373
   PubMed Web of Science ®Google Scholar
• Hagen T, Taylor CT, Lam F, Moncada S. Redistribution of intracellular oxygen in hypoxia by nitric oxide: Effect on HIF1alpha. Science 2003; 302: 1975–1978
   PubMed Web of Science ®Google Scholar
• Schroedl C, McClintock DS, Scott GR, Chandel NS. Hypoxic but not anoxic stabilization of HIF-1α requires mitochondrial reactive oxygen species. Am J Physiol Lung Cell Mol Physiol 2002; 283: L922–L931
   PubMedGoogle Scholar
• Wang F, Sekine H, Kikuchi Y, Takasaki C, Miura C, Heiwa O, Shuin T, Fujii-Kuriyama Y, Sogawa K. HIF-1alpha-prolyl hydroxylase: Molecular target of nitric oxide in the hypoxic signal transduction pathway. Biochem Biophys Res Commun 2002; 295: 657–662
   PubMedGoogle Scholar
• Kozhukhar AV, Yasinska IM, Sumbayev VV. Nitric oxide inhibits HIF-1α protein accumulation under hypoxic conditions: Implication of 2-oxoglutarate and iron. Biochimie 2005, in press
   PubMedGoogle Scholar
• Moncada S, Erusalimsky JD. Does nitric oxide modulate mitochondrial energy generation and apoptosis?. Nat Rev Mol Cell Biol 2002; 3: 214–220
   PubMed Web of Science ®Google Scholar
• Brennan T, Frenkel C. Involvement of hydrogen peroxide in the regulation of senescence in pear. Plant Physiol 1977; 59: 411–416
   PubMed Web of Science ®Google Scholar
• Callapina M, Zhou J, Schnitzer S, Metzen E, Lohr C, Deitmer JW, Brüne B. Nitric oxide reverses desferrioxamine- and hypoxia-evoked HIF-1α accumulation—implications for prolyl hydroxylase activity and iron. Exp Cell Res 2005; 306: 274–284
   PubMedGoogle Scholar
• Callapina M, Zhou J, Schmid T, Kohl R, Brüne B. NO restores HIF-1α prolyl-hydroxylation during hypoxia: Role of reactive oxygen species. Free Radic Biol Med 2005; 39: 925–936
   PubMedGoogle Scholar