The endogenous neurotransmitter, serotonin, modifies neuronal nitric oxide synthase activities

References

• Simpson KL, Waterhouse BD, Lin RC. Differential expression of nitric oxide in serotonergic projection neurons: Neurochemical identification of dorsal raphe inputs to rodent trigeminal somatosensory targets. J Comp Neurol 2003; 466: 495–512
   PubMedGoogle Scholar
• Sarchielli P, Alberti A, Russo S, Codini M, Panico R, Floridi A, Gallai V. Nitric oxide pathway, Ca2+ and serotonin content in platelets from patients suffering from chronic daily headache. Cephalalgia 1999; 19: 810–816
   PubMedGoogle Scholar
• Kadowaki M, Kuramoto H, Kuwahara A. Morphological relationship between serotoninergic neurons and nitrergic neurons for electrolytes secretion in the submucous plexus of the guinea pig distal colon. Brain Res 1999; 831: 288–291
   PubMedGoogle Scholar
• Alderton WK, Cooper CE, Knowles RG. Nitric oxide synthases: Structure, function and inhibition. Biochem J 2001; 357: 593–615
   PubMed Web of Science ®Google Scholar
• Weissman BA, Jones CL, Liu Q, Gross SS. Activation and inactivation of neuronal nitric oxide synthase: Characterization of Ca(2+)-dependent [125I]calmodulin binding. Eur J Pharmacol 2002; 435: 9–18
   PubMedGoogle Scholar
• Pou S, Keaton L, Surichamorn W, Rosen GM. Mechanism of superoxide generation by neuronal nitric-oxide synthase. J Biol Chem 1999; 274: 9573–9580
   PubMedGoogle Scholar
• Rosen GM, Tsai P, Weaver J, Porasuphatana S, Roman LJ, Starkov AA, Fiskum G, Pou S. The role of tetrahydrobiopterin in the regulation of neuronal nitric-oxide synthase-generated superoxide. J Biol Chem 2002; 277: 40275–40280
   PubMed Web of Science ®Google Scholar
• Tsai P, Weaver J, Cao GL, Pou S, Roman LJ, Starkov AA, Rosen GM. l-arginine regulates neuronal nitric oxide synthase production of superoxide and hydrogen peroxide. Biochem Pharmacol 2005; 69: 971–979
   PubMedGoogle Scholar
• Kuhn D, Arthur R. Inactivation of brain tryptophan hydroxylase by nitric oxide. J Neurochem 1996; 67: 1072–1077
   PubMed Web of Science ®Google Scholar
• Kuhn D, Arthur R. Inactivation of tryptophan hydroxylase by nitric oxide: Enhancement by tetrahydropterin. J Neurochem 1997; 68: 1495–1502
   PubMed Web of Science ®Google Scholar
• Ishida T, Kawashima S, Hirata K, Yokoyama M. Nitric oxide is produced via 5HT1B and 5HT2B receptor activation in human coronary artery endothelial cells. Kobe J Med Sci 1998; 44: 51–63
   PubMedGoogle Scholar
• Stoner M, Scherr A, Lee J, Wolfe L, Kellum J. Nitric oxide is a neurotransmitter in the chloride secretory response to serotonin in rat colon. Surgery 2000; 128: 240–245
   PubMed Web of Science ®Google Scholar
• Ramos AJ, Tagliaferro P, Lopez-Costa JJ, Lopez EM, Pecci Saavedra J, Brusco A. Neuronal and inducible nitric oxide synthase immunoreactivity following serotonin depletion. Brain Res 2002; 958: 112–121
   PubMedGoogle Scholar
• Murphy ME, Noack E. Nitric oxide assay using hemoglobin method. Methods Enzymol 1994; 233: 240–250
   PubMed Web of Science ®Google Scholar
• Zhao H, Joseph J, Zhang H, Karoui H, Kalyanaraman B. Synthesis and biochemical applications of a solid cyclic nitrone spin trap: A relatively superior trap for detecting superoxide anions and glutathiyl radicals. Free Radic Biol Med 2001; 31: 599–606
   PubMed Web of Science ®Google Scholar
• Ask K, Dijols S, Giroud C, Casse L, Frapart YM, Sari MA, Kim KS, Stuehr DJ, Mansuy D, Camus P, Boucher JL. Reduction of nilutamide by NO synthases: Implications for the adverse effects of this nitroaromatic antiandrogen drug. Chem Res Toxicol 2003; 16: 1547–1554
   PubMed Web of Science ®Google Scholar
• Stuehr DJ, Ikeda-Saito M. Spectral characterization of brain and macrophage nitric oxide synthases. Cytochrome P-450-like hemeproteins that contain a flavin semiquinone radical. J Biol Chem 1992; 267: 20547–20550
   PubMed Web of Science ®Google Scholar
• Bredt DS, Snyder SH. Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum. Proc Natl Acad Sci USA 1989; 86: 9030–9033
   PubMed Web of Science ®Google Scholar
• Feelisch M, Kubitzek D. The oxyhemoglobin assay. Methods in nitric oxide research, M Feelisch, JS Stamler. John Wiley & Sons Ltd. 1996; 455–477
   Google Scholar
• Heinzel B, John M, Klatt P, Bohme E, Mayer B. Ca2+/calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase. Biochem J 1992; 281(Pt 3)627–630
   PubMedGoogle Scholar
• Bielski BHJ, Allen AO. Mechanism of the disproportionation of superoxide radicals. J Phys Chem 1977; 81: 1048–1050
   Web of Science ®Google Scholar
• Tsai P, Ichikawa K, Mailer C, Pou S, Halpern HJ, Robinson BH, Nielsen R, Rosen GM. Esters of 5-carboxyl-5-methyl-l-pyrroline N-oxide: A family of spin traps for superoxide. J Org Chem 2003; 68: 7811–7817
   PubMed Web of Science ®Google Scholar
• Keszler A, Kalyanaraman B, Hogg N. Comparative investigation of superoxide trapping by cyclic nitrone spin traps: The use of singular value decomposition and multiple linear regression analysis. Free Radic Biol Med 2003; 35: 1149–1157
   PubMed Web of Science ®Google Scholar
• Pou S, Pou WS, Bredt DS, Snyder SH, Rosen GM. Generation of superoxide by purified brain nitric oxide synthase. J Biol Chem 1992; 267: 24173–24176
   PubMed Web of Science ®Google Scholar
• Blanchard B, Dendane M, Gallard J, Houee-Levin C, Karim A, Payen D, Launay J, Ducrocq C. Oxidation, nitrosation, nitration of serotonin by nitric oxide-derived nitrogen oxides: Biological implications in the rat vascular system. Nitric Oxide 1997; 1: 442–452
   PubMed Web of Science ®Google Scholar
• Kelm M, Dahmann R, Wink D, Feelisch M. The nitric oxide/superoxide assay. Insights into the biological chemistry of the NO/ interaction. J Biol Chem 1997; 272: 9922–9932
   PubMed Web of Science ®Google Scholar
• Sutton HC, Roberts PB, Winterbourn CC. The rate of reaction of superoxide radical ion with oxyhaemoglobin and methaemoglobin. Biochem J 1976; 155: 503–510
   PubMed Web of Science ®Google Scholar
• Schmidt K, Klatt P, Mayer B. Reaction of peroxynitrite with oxyhaemoglobin: Interference with photometrical determination of nitric oxide. Biochem J 1994; 301(Pt 3)645–647
   PubMedGoogle Scholar
• Romero N, Radi R, Linares E, Augusto O, Detweiler CD, Mason RP, Denicola A. Reaction of human hemoglobin with peroxynitrite. Isomerization to nitrate and secondary formation of protein radicals. J Biol Chem 2003; 278: 44049–44057
   PubMed Web of Science ®Google Scholar
• Weiss SJ. Neutrophil-mediated methemoglobin formation in the erythrocyte. The role of superoxide and hydrogen peroxide. J Biol Chem 1982; 257: 2947–2953
   PubMed Web of Science ®Google Scholar
• Cardounel AJ, Xia Y, Zweier JL. Endogenous methylarginines modulate superoxide as well as nitric oxide generation from neuronal nitric-oxide synthase: Differences in the effects of monomethyl- and dimethylarginines in the presence and absence of tetrahydrobiopterin. J Biol Chem 2005; 280: 7540–7549
   PubMedGoogle Scholar
• Kissner R, Nauser T, Bugnon P, Lye PG, Koppenol WH. Formation and properties of peroxynitrite as studied by laser flash photolysis, high-pressure stopped-flow technique, and pulse radiolysis. Chem Res Toxicol 1997; 10: 1285–1292
   PubMed Web of Science ®Google Scholar
• Pfeiffer S, Mayer B. Lack of tyrosine nitration by peroxynitrite generated at physiological pH. J Biol Chem 1998; 273: 27280–27285
   PubMed Web of Science ®Google Scholar
• Weaver J, Porasuphatana S, Tsai P, Pou S, Roman LJ, Rosen GM. A comparative study of neuronal and inducible nitric oxide synthases: Generation of nitric oxide, superoxide, and hydrogen peroxide. Biochim Biophys Acta 2005; 1726: 302–308
   PubMedGoogle Scholar
• Pignitter M, Gorren AC, Nedeianu S, Schmidt K, Mayer B. Inefficient spin trapping of superoxide in the presence of nitric-oxide: Implications for studies on nitric-oxide synthase uncoupling. Free Radic Biol Med 2006; 41: 455–463
   PubMedGoogle Scholar
• Kotsonis P, Frey A, Frohlich LG, Hofmann H, Reif A, Wink DA, Feelisch M, Schmidt HH. Autoinhibition of neuronal nitric oxide synthase: Distinct effects of reactive nitrogen and oxygen species on enzyme activity. Biochem J 1999; 340(Pt 3)745–752
   PubMedGoogle Scholar
• Palumbo A, Astarita G, d'Ischia M. Inhibition of neuronal nitric oxide synthase by 6-nitrocatecholamines, putative reaction products of nitric oxide with catecholamines under oxidative stress conditions. Biochem J 2001; 356: 105–110
   PubMedGoogle Scholar
• Leon J, Macias M, Escames G, Camacho E, Khaldy H, Martin M, Espinosa A, Gallo MA, Acuna-Castroviejo D. Structure-related inhibition of calmodulin-dependent neuronal nitric-oxide synthase activity by melatonin and synthetic kynurenines. Mol Pharmacol 2000; 58: 967–975
   PubMed Web of Science ®Google Scholar
• Demady DR, Jianmongkol S, Vuletich JL, Bender AT, Osawa Y. Agmatine enhances the NADPH oxidase activity of neuronal NO synthase and leads to oxidative inactivation of the enzyme. Mol Pharmacol 2001; 59: 24–29
   PubMed Web of Science ®Google Scholar
• Margolis AS, Porasuphatana S, Rosen GM. Role of paraquat in the uncoupling of nitric oxide synthase. Biochim Biophys Acta 2000; 1524: 253–257
   PubMedGoogle Scholar
• Vasquez-Vivar J, Martasek P, Hogg N, Masters BS, Pritchard KA, Jr., Kalyanaraman B. Endothelial nitric oxide synthase-dependent superoxide generation from adriamycin. Biochemistry 1997; 36: 11293–11297
   PubMed Web of Science ®Google Scholar
• Miller RT. Dinitrobenzene-mediated production of peroxynitrite by neuronal nitric oxide synthase. Chem Res Toxicol 2002; 15: 927–934
   PubMedGoogle Scholar
• Wrona MZ, Dryhurst G. Oxidation chemistry of 5-hydroxytryptamine. 1. Mechanism and products formed at micromolar concentrations. J Org Chem 1987; 52: 2817–2825
   Google Scholar
• Choi HJ, Kim SW, Im JH, Lee SG, Kim M, Hwang O. Utilization of exogenous tetrahydrobiopterin in nitric oxide synthesis in human neuroblastoma cell line. Neurosci Lett 2003; 352: 89–92
   PubMedGoogle Scholar