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Original

New method for the detection of reactive oxygen species in anti-tumoural activity of adriamycin: A comparison between hypoxic and normoxic cells

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Pages 124-134 | Received 17 Jul 2007, Published online: 07 Jul 2009

References

  • Gewirtz DA. A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. Biochem Pharmacol 1999; 57: 727–741
  • Minotti G, Menna P, Salvatorelli E, Cairo G, Gianni L. Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol Rev 2004; 56: 185–229
  • Cullinane C, Cutts SM, van Rosmalen A, Phillips DR. Formation of adriamycin-DNA adducts in vitro. Nucleic Acids Res 1994; 22: 2296–2303
  • Davies KJA, Doroshow JH. Redox cycling of anthracyclines by cardiac mitochondria. I. Anthracycline radical formation by NADH dehydrogenase. J Biol Chem 1986; 261: 3060–3067
  • Doroshow JH, Davies KJA. Redox cycling of anthracyclines by cardiac mitochondria. II. Formation of superoxide anion, hydrogen peroxide and hydroxyl radical. J Biol Chem 1986; 261: 3068–3074
  • Quiles JL, Huertas JR, Battino M, Mataix J, Ramirez-Tortosa MC. Antioxidant nutrients and adriamycin toxicity. Toxicology 2002; 180: 79–95
  • Teicher BA, Holden SA, Al-Achi A, Herman TS. Classification of antineoplastic treatments by their differential toxicity toward putative oxygenated and hypoxic tumor subpopulations in vivo in the FSaIIC murine fibrosarcoma. Cancer Res 1990; 50: 3339–3344
  • Frederiksen LJ, Siemens DR, Heaton JP, Maxwell LR, Adams MA, Graham CH. Hypoxia induced resistance to doxorubicin in prostate cancer cells is inhibited by low concentrations of glyceryl trinitrate. J Urol 2003; 170: 1003–1007
  • Song X, Liu X, Chi W, Liu Y, Wei L, Wang X, Yu J. Hypoxia-induced resistance to cisplatin and doxorubicin in non-small cell lung cancer is inhibited by silencing of HIF-1a gene. Cancer Chemother Pharmacol 2006; 58: 776–784
  • Höckel M, Vaupel P. Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects. J Natl Cancer Inst 2001; 93: 266–276
  • Wheeler RH, Dirks JW, Lunardi I, Nemiroff MJ. Effect of hyperbaric oxygen on the cytotoxicity of adriamycin and nitrogen mustard in cultured Burkitt's lymphoma cells. Cancer Res 1979; 39: 370–375
  • Kalns J, Krock L, Piepmeier EJ. The effect of hyperbaric oxygen on growth and chemosensitivity of metastatic prostate cancer. Anticancer Res 1998; 18: 363–368
  • Rharass T, Ribou AC, Vigo J, Salmon JM. Effect of adriamycin treatment on the lifetime of pyrene butyric acid in single living cells. Free Radic Res 2005; 39: 581–588
  • Rharass T, Vigo J, Salmon JM, Ribou AC. Variation of 1-pyrenebutyric acid fluorescence lifetime in single living cells with molecules increasing or decreasing reactive oxygen species levels. Anal Biochem 2006; 357: 1–8
  • Lautier D, Lahmy S, Canitrot Y, Vigo J, Viallet P, Salmon JM. Detection of human leukemia cells with multidrug resistant phenotype using multilabeling with fluorescent dyes. Anticancer Res 1993; 13: 1557–1564
  • Rocchi E, Vigo J, Viallet P, Bonnard I, Salmon JM. Multiwavelength videomicrofluorimetric study of cytotoxic effects of a marine peptide didemnin B on a normal and MDR resistant CCRF-CEM cell lines. Anticancer Res 2000; 20: 987–996
  • Savatier J, Vigo J, Salmon JM. Monitoring cell cycle distributions in living cells by videomicrofluorometry and discriminant factorial analysis. Cytometry A 2003; 55A: 8–14
  • Vigo J, Salmon JM, Lahmy S, Viallet P. Fluorescent image cytometry: from qualitative to quantitative measurements. Anal Cell Pathol 1991; 3: 145–165
  • Ribou AC, Vigo J, Salmon JM. Lifetime of fluorescent pyrene butyric acid probe in single living cells for measurement of oxygen fluctuation. Photochem Photobiol 2004; 80: 274–280
  • Nelder JA, Mead R. Numerical recipes; minimization or maximization of function. Comput J 1965; 7: 308–313
  • Stern O, Volmer M. The extinction period of fluorescence. Phys Z 1919; 20: 183–188
  • Zamzami N, Marchetti P, Castedo M, Zanin C, Vayssière JC, Petit PX, Kroemer G. Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo. J Exp Med 1995; 181: 1661–1672
  • Hagen TM, Yowe DL, Bartholomew JC, Wehr CM, Do KL, Park JY, Ames BN. Mitochondrial decay in hepatocytes from old rats: membrane potential declines, heterogeneity and oxidants increase. Proc Natl Acad Sci USA 1997; 94: 3064–3069
  • Robinson H, Gao YG, Bauer C, Roberts C, Switzer C, Wang A. H. 2'-deoxyisoguanosine adopts more than one tautomer to form base pairs with thymidine observed by high-resolution crystal structure analysis. Biochemistry 1998; 37: 10897–10905
  • Fossati G, Moulding DA, Spiller DG, Moots RJ, White MRH, Edwards SW. The mitochondrial network of human neutrophils: role in chemotaxis, phagocytosis, respiratory burst activation, and commitment to apoptosis. J Immunol 2003; 170: 1964–1972
  • Robertson JD, Orrenius S, Zhivotovsky B. Nuclear events in apoptosis. J Struct Biol 2000; 129: 346–358
  • Proskuryakov SY, Konoplyannikov AG, Gabai VL. Necrosis: a specific form of programmed cell death?. Exp Cell Res 2003; 283: 1–16
  • Duranteau J, Chandel NS, Kulisz A, Shao Z, Schumacker PT. Intracellular signaling by reactive oxygen species during hypoxia in cardiomyocytes. J Biol Chem 1998; 273: 11619–11624
  • Guzy RD, Hoyos B, Robin E, Chen H, Liu L, Mansfield KD, Simon MC, Hammerling U, Schumacker PT. Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing. Cell Metab 2005; 1: 401–408
  • Vaux EC, Metzen E, Yeates KM, Ratcliffe PJ. Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain. Blood 2001; 98: 296–302
  • Michelakis ED, Thebaud B, Weir EK, Archer SL. Hypoxic pulmonary vasoconstriction: redox regulation of O2-sensitive K+ channels by a mitochondrial O2-sensor in resistance artery smooth muscle cells. J Mol Cell Cardiol 2004; 37: 1119–1136
  • Göhde W, Meistrich M, Meyn R, Schumann J, Johnston D, Barlogie B. Cell-cycle phase-dependence of drug-induced cycle progression delay. J Histochem Cytochem 1979; 27: 470–473
  • Traganos F, Israel M, Silber R, Seshadri R, Kirschenbaum S, Potmesil M. Effects of new N-alkyl analogues of adriamycin on in vitro survival and cell cycle progression of L1210 cells. Cancer Res 1985; 45: 6273–6279
  • Gebhardt MC, Kusuzaki K, Mankin HJ, Springfield DS. An assay to measure adriamycin binding in osteosarcoma cells. J Orthop Res 1994; 12: 621–627
  • Swift LP, Rephaeli A, Nudelman A, Phillips DR, Cutts SM. Doxorubicin-DNA adducts induce a non-topoisomerase II-mediated form of cell death. Cancer Res 2006; 66: 4863–4871
  • Skladanowski A, Konopa J. Adriamycin and daunomycin induce programmed cell death (apoptosis) in tumour cells. Biochem Pharmacol 1993; 46: 375–382
  • Ling YH, Priebe W, Perez-Soler R. Apoptosis induced by anthracycline antibiotics in P388 parent and multidrug-resistant cells. Cancer Res 1993; 53: 1845–1852
  • Müller I, Jenner A, Bruchell G, Niethammer D, Halliwell B. Effect of concentration on the cytotoxic mechanism of doxorubicin—apoptosis and oxidative DNA damage. Biochem Biophys Res Commun 1997; 230: 254–257
  • Hockenbery DM, Oltvai ZN, Yin XM, Milliman CL, Korsmeyer SJ. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 1993; 75: 241–251
  • Slater AFG, Nobel CSI, Orrenius S. The role of intracellular oxidants in apoptosis. Biochim Biophys Acta 1995; 1271: 59–62

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