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Original

Effects of amyloid-beta peptides on hydrogen peroxide-metabolizing enzymes in rat brain in vivo

, DSc &
Pages 564-573 | Received 23 Mar 2008, Published online: 07 Jul 2009

References

  • Suo Z, Fang C, Crawford F, Mullan M. Superoxide free radical and intracellular calcium mediate A beta(1–42) induced endothelial toxicity. Brain Res 1997; 762: 144–152
  • Parks JK, Smith TS, Trimmer PA, Bennett JP, Jr, Parker WD, Jr. Neurotoxic Abeta peptides increase oxidative stress in vivo through NMDA-receptor and nitric-oxide-synthase mechanisms, and inhibit complex IV activity and induce a mitochondrial permeability transition in vitro. J Neurochem 2001; 76: 1050–1056
  • Hirai K, Hayako H, Kato K, Miyamoto M. Idebenone protects hippocampal neurons against amyloid beta-peptide-induced neurotoxicity in rat primary cultures. Naunyn-Schmiedeberg. s Arch Pharmacol 1998; 358: 582–585
  • Cheah KS, Chance B. The oxidase systems of Ascaris-muscle mitochondria. Biochim Biophys Acta 1970; 223: 55–60
  • Youdim MB, Finberg JP, Tipton KF. Monoamine oxidase. Hbk Exp Pharmacol 1988; 90: 119–192
  • Paxinos G, Watson C. The rat brain in stereotaxic coordinates–The new coronal set5th ed. Academic Press, New York 2004
  • Podolski IYA, Podlubnaya ZA, Kosenko EA, Mugantseva EA, Makarova EG, Marsagishvili LG, Shpagina MD, Kaminsky YUG, Andrievsky GV, Klochkov VK. Effects of hydrated forms of C60 fullerene on amyloid β-peptide fibrillization in vitro and performance of the cognitive task. J Nanosci Nanotechnol 2007; 7: 1479–1485
  • Olariu A, Yamada K, Mamiya T, Hefco V, Nabeshima T. Memory impairment induced by chronic intracerebroventricular infusion of beta-amyloid (1–40) involves downregulation of protein kinase C. Brain Res 2002; 957: 278–286
  • Kosenko E, Kaminsky Y, Stavrovskaya IG, Felipo V. Alteration of mitochondrial calcium homeostasis by ammonia-induced activation of NMDA receptors in rat brain in vivo. Brain Res 2000; 880: 139–146
  • Kosenko E, Felipo V, Montoliu C, Grisolia S, Kaminsky Yu. Effects of acute hyperammonemia in vivo on oxidative metabolism in nonsynaptic rat brain mitochondria. Metabol Brain Dis 1996; 12: 69–82
  • Kosenko E, Venediktova N, Kaminsky Y, Montoliu C, Felipo V. Preparation and handling of brain mitochondria useful to study uptake and release of calcium. Brain Res. Brain Res Protocols 2001; 7: 248–254
  • Loschen G, Flohe L, Chance B. Respiratory chain linked H2O2 production in pigeon heart mitochondria. FEBS Lett 1971; 18: 261–264
  • Aebi HE. Catalase. Methods of enzymatic analysis. Vol. 3, HU Bergmeyer. Wiley, New York 1984; 273–286
  • Beckman JS, Parks DA, Pearson JD, Marshall PA, Freeman BA. A sensitive fluorometric assay for measuring xanthine dehydrogenase and oxidase in tissues. Free Radic Biol Med 1989; 6: 607–615
  • Lawrence RA, Burk RF. Glutathione peroxidase activity in selenium-deficient rat liver. Biochem Biophys Res Commun 1976; 71: 952–958
  • Kosenko E, Venediktova N, Kaminsky Y, Montoliu C, Felipo V. Sources of oxygen radicals in brain in acute ammonia intoxication in vivo. Brain Res 2003; 981: 193–200
  • Beauchamp C, Fridovich I. Improved assaus and an assay applicable to acrylamide gels. Anal Biochem 1971; 44: 276–287
  • Rashidi MR, Smith JA, Clarke SE, Beedham C. In vitro oxidation of famciclovir and 6-deoxypenciclovir by aldehyde oxidase from human, guinea pig, rabbit, and rat liver. Drug Metab Dispos Biol Fate Chem 1997; 25: 805–813
  • LeVine H., 3rd. Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution. Protein Sci 1993; 2: 404–410
  • Boveris A. Mitochondrial production of superoxide radical and hydrogen peroxide. Adv Exp Med Biol 1977; 78: 67–82
  • Behl C, Dis JB, Lesley R, Schubert D. Hydrogen peroxide mediates amyloid beta protein toxicity. Cell 1994; 77: 817–827
  • Harris ME, Hensley K, Butterfield DA, Leedle RA, Carney JM. Direct evidence of oxidative injury produced by the Alzheimer's beta-amyloid peptide (1–40) in cultured hippocampal neurons. Exp Neurol 1995; 131: 193–202
  • Aliev G, Smith MA, de la Torre JC, Perry G. Mitochondria as a primary target for vascular hypoperfusion and oxidative stress in Alzheimer's disease. Mitochondrion 2004; 4: 649–663
  • Manczak M, Anekonda TS, Henson E, Park BS, Quinn J, Red PH. Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression. Human Mol Genet 2006; 15: 1437–1449
  • Aleardi AM, Benard G, Augereau O, Malgat M, Talbot JC, Mazat JP, Letellier T, Dachary-Prigent J, Solaini GC, Rossignol R. Gradual alteration of mitochondrial structure and function by beta-amyloids: importance of membrane viscosity changes, energy deprivation, reactive oxygen species production, and cytochrome c release. J Bioenerget Biomemb 2005; 37: 207–225
  • Moreira PI, Santos MS, Sena C, Nunes E, Seica R, Oliveira CR. CoQ10 therapy attenuates amyloid beta-peptide toxicity in brain mitochondria isolated from aged diabetic rats. Exp Neurol 2005; 196: 112–119
  • Xu J, Chen S, Ku G, Ahmed SH, Xu J, Chen H, Hsu CY. Amyloid beta peptide-induced cerebral endothelial cell death involves mitochondrial dysfunction and caspase activation. J Cerebr Blood Flow Metab 2001; 21: 702–710
  • Pereira C, Santos MS, Oliveira C. Mitochondrial function impairment induced by amyloid beta-peptide on PC12 cells. Neuroreport 1998; 9: 1749–1755
  • Pike CJ, Walencewicz-Wasserman AJ, Kosmoski J, Cribbs DH, Glabe CG, Cotman CW. Structure-activity analyses of beta-amyloid peptides: contributions of the beta 25–35 region to aggregation and neurotoxicity. J Neurochem 1995; 64: 253–265
  • Shearman MS, Ragan CI, Iversen LL. Inhibition of PC12 cell redox activity is a specific, early indicator of the mechanism of beta-amyloid-mediated cell death. Proc Natl Acad Sci USA 1994; 91: 1470–1474
  • Hensley K, Carney JM, Mattson MP, Aksenova M, Harris M, Wu JF, Floyd RA, Butterfield DA. A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease. Proc Natl Acad Sci USA 1994; 91: 3270–3274
  • Blackley HK, Sanders G, Davies MC, Roberts CJ, Tendler SJ, Wilkinson MJ. In-situ atomic force microscopy study of beta-amyloid fibrillization. J Mol Biol 2000; 298: 833–840
  • Hughes E, Burke RM, Doig AJ. Inhibition of toxicity in the β-amyloid peptide fragment β-(25–35) using N-methylated derivatives. A general strategy to prevent amyloid formation. J Biol Chem 2000; 275: 25109–25115
  • Yankner BA, Dawes LR, Fisher S, Villa-Komaroff L, Oster-Granite ML, Neve RL. Neurotoxicity of a fragment of amyloid precursor associated with Alzheimer's disease. Science 1989; 245: 417–420
  • Kaneko I, Yamada N, Sakuraba Y, Kamenosono M, Tutumi S. Suppression of mitochondrial succinate dehydrogenase, a primary target of β-amyloid, and its derivative racemized at Ser residue. J Neurochem 1995; 65: 2585–2593
  • Kubo T, Nishimura S, Kumagae Y, Kaneko I. In vivo conversion of racemized β-amyloid ([D-Ser26]Aβ1–40) to truncated and toxic fragments ([D-Ser26]A(25–35/40) and fragment presence in the brains of Alzheimer's patients. J Neurosci Res 2002; 70: 474–483
  • Shapira R, Austin GE, Mirra SS. Neuritic plaque amyloid in Alzheimer's disease is highly racemized. J Neurochem 1988; 50: 69–74
  • Kaneko I, Morimoto K, Kubo T. Drastic neuronal loss in vivo by β-amyloid racemized at Ser(26) residue: conversion of non-toxic [D-Ser(26)] β-amyloid 1–40 to toxic and proteinase-resistant fragments. Neuroscience 2001; 104: 1003–1011
  • Kubo T, Kumagae Y, Miller CA, Kaneko I. β-amyloid racemized at the Ser26 residue in the brains of patients with Alzheimer disease: implications in the pathogenesis of Alzheimer disease. J Neuropathol Exp Neurol 2003; 62: 248–254
  • Gelfanova V, Higgs RE, Dean RA, Holtzman DM, Farlow MR, Sierners ER, Boodhoo A, Qian YW, He X, Jin Z, Fisher DL, Cox KL, Hale JE. Quantitative analysis of amyloid-β peptides in cerebrospinal fluid using immunoprecipitation and MALDI-Tof mass spectrometry. Breef Funct Genom Proteom 2007; 6: 149–158
  • Lanz TA, Himes CS, Pallante G, Adams L, Yamazaki S, Amore B, Merchant KM. The gamma-secretase inhibitor N-[N-(3,5-difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester reduces A beta levels in vivo in plasma and cerebrospinal fluid in young (plaque-free) and aged (plaque-bearing) Tg2576 mice. J Pharmacol Exp Therapeut 2003; 305: 864–871
  • Lanz TA, Karmilowicz MJ, Wood KM, Pozdnyakov N, Du P, Piotrowski MA, Brown TM, Nolan CE, Richter KE, Finley JE, Fei Q, Ebinghaus CF, Chen YL, Spracklin DK, Tate B, Geoghegan KF, Lau LF, Auperin DD, Schachter JB. Concentration-dependent modulation of amyloid-β in vivo and in vitro using the γ-secretase inhibitor, LY-450139. J Pharmacol Exp Therapeut 2006; 319: 924–933
  • Beglopoulos V, Sun X, Saura CA, Lemere CA, Kim RD, Shen J. Reduced beta-amyloid production and increased inflammatory responses in presenilin conditional knock-out mice. J Biol Chem 2004; 279: 46907–46914
  • Li Y, Qin HQ, Chen QS, Wang JJ. Neurochemical and behavioral effects of the intrahippocampal co-injection of beta-amyloid protein 1–40 and ibotenic acid in rats. Life Sci 2005; 76: 1189–1197
  • Ghiso J, Shayo M, Calero M, Ng D, Tomidokoro Y, Gandy S, Rostagno A, Frangione B. Systemic catabolism of Alzheimer's Aβ40 and Aβ42. J Biol Chem 2004; 279: 45897–45908
  • Saez-Valero J, de Ceballos ML, Small DH, de Felipe C. Changes in molecular isoform distribution of acetylcholinesterase in rat cortex and cerebrospinal fluid after intracerebroventricular administration of amyloid beta-peptide. Neurosci Lett 2002; 325: 199–202
  • Aksenov MY, Aksenova MV, Markesbery WR, Butterfield DA. Amyloid beta-peptide (1–40)-mediated oxidative stress in cultured hippocampal neurons. Protein carbonyl formation, CK BB expression, and the level of Cu, Zn, and Mn SOD mRNA. J Mol Neurosci 1998; 10: 181–192
  • Anantharaman M, Tangpong J, Keller JN, Murphy MP, Markesbery WR, Kiningham KK, St Clair DK. Beta-amyloid mediated nitration of manganese superoxide dismutase: implication for oxidative stress in a APPNLH/NLH X PS-1P264L/P264L double knock-in mouse model of Alzheimer's disease. Am J Pathol 2006; 168: 1608–1618
  • Westlund KN, Krakower TJ, Kwan SW, Abell CW. Intracellular distribution of monoamine oxidase A in selected regions of rat and monkey brain and spinal cord. Brain Res 1993; 612: 221–230
  • Levitt P, Pintar JE, Breakefield XO. Immunocytochemical demonstration of monoamine oxidase B in brain astrocytes and serotonergic neurons. Proc Natl Acad Sci USA 1982; 79: 6385–6389
  • Thomas T. Monoamine oxidase-B inhibitors in the treatment of Alzheimer's disease. Neurobiol Aging 2000; 21: 343–348
  • Sramek JJ, Cutler NR. Recent developments in the drug treatment of Alzheimer's disease. Drugs Aging 1999; 14: 359–373
  • Song W, Zhou LJ, Zheng SX, Zhu XZ. Amyloid-beta 25–35 peptide induces expression of monoamine oxidase B in cultured rat astrocytes. Acta Pharmacol Sinica 2000; 21: 557–563
  • Brigelius-Flohe R. Glutathione peroxidases and redox-regulated transcription factors. Biol Chem 2006; 387: 1329–1335
  • Kosenko E, Kaminsky Y, Kaminsky A, Valencia M, Lee L, Hermenegildo C, Felipo V. Superoxide production and antioxidant enzymes in ammonia intoxication in rats. Free Radic Res 1997; 27: 637–644
  • Kosenko E, Kaminsky Y, Lopata O, Muravyov N, Kaminsky A, Hermenegildo C, Felipo V. Nitroarginine, an inhibitor of nitric oxide synthase, prevents changes in superoxide radical and antioxidant enzymes induced by ammonia intoxication. Metab Brain Dis 1998; 13: 29–41
  • Kosenko E, Kaminsky Y, Stavroskaya IG, Felipo V. Alteration of mitochondrial calcium homeostasis by ammonia-induced activation of NMDA receptors in rat brain in vivo. Brain Res 2000; 880: 139–146
  • Venediktova NI, Kosenko EA, Kaminsky YG. Antioxidant enzymes, hydrogen peroxide metabolism, and respiration in rat heart during experimental hyperammonemia. Biol Bull 2006; 33: 281–286
  • Wang X, Su B, Perry G, Smith MA, Zhu X. Insights into amyloid-beta-induced mitochondrial dysfunction in Alzheimer disease. Free Radic Biol Med 2007; 43: 1569–1573
  • Caspersen C, Wang N, Yao J, Sosunov A, Chen X, Lustbader JW, Xu HW, Stern D, McKhann G, Yan SD. Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease. FASEB J 2005; 19: 2040–2041
  • Xiao XQ, Wang R, Han YF, Tang XC. Protective effects of huperzine A on beta-amyloid(25–35) induced oxidative injury in rat pheochromocytoma cells. Neurosci Lett 2000; 286: 155–158
  • Corte ED, Stirpe F. The regulation of rat liver xanthine oxidase. Involvement of thiol groups in the conversion of the enzyme activity from dehydrogenase (type D) into oxidase (type O) and purification of the enzyme. Biochem J 1972; 126: 739–745
  • Kaminsky YG, Kosenko EA, Venediktova NI, Kaminsky AY, Suvorova MM, Maltsev AV, Ataullakhanov FI, Karnaukhov VN, Karnaukhova EV. The role of glutamate receptors and mitochondria in neurodegeneration on Alzheimer's disease models. Almanakh ‘Gerontologia I Geriatria’ 2004;3:89–93. In Russian.

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