RNA oxidation: A contributing factor or an epiphenomenon in the process of neurodegeneration

References

• Lin MT, Beal MF. Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 2006; 443: 787–795
   PubMed Web of Science ®Google Scholar
• Juurlink BH, Paterson PG. Review of oxidative stress in brain and spinal cord injury: suggestions for pharmacological and nutritional management strategies. J Spinal Cord Med 1998; 21: 309–334
   PubMedGoogle Scholar
• Patel M. Mitochondrial dysfunction and oxidative stress: cause and consequence of epileptic seizures. Free Radic Biol Med 2004; 37: 1951–1962
   PubMed Web of Science ®Google Scholar
• Fiala ES, Conaway CC, Mathis JE. Oxidative DNA and RNA damage in the livers of Sprague- Dawley rats treated with the hepatocarcinogen 2-nitropropane. Cancer Res 1989; 49: 5518–5522
   PubMed Web of Science ®Google Scholar
• Wamer WG, Yin JJ, Wei RR. Oxidative damage to nucleic acids photosensitized by titanium dioxide. Free Radic Biol Med 1997; 23: 851–858
   PubMed Web of Science ®Google Scholar
• Nunomura A, Perry G, Pappolla MA, Wade R, Hirai K, Chiba S, Smith MA. RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease. J Neurosci 1999; 19: 1959–1964
   PubMed Web of Science ®Google Scholar
• Zhang J, Perry G, Smith MA, Robertson D, Olson SJ, Graham DG, Montine TJ. Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons. Am J Pathol 1999; 154: 1423–1429
   PubMed Web of Science ®Google Scholar
• Nunomura A, Perry G, Pappolla MA, Friedland RP, Hirai K, Chiba S, Smith MA. Neuronal oxidative stress precedes amyloid-beta deposition in Down syndrome. J Neuropathol Exp Neurol 2000; 59: 1011–1017
   PubMed Web of Science ®Google Scholar
• Nunomura A, Chiba S, Kosaka K, Takeda A, Castellani RJ, Smith MA, Perry G. Neuronal RNA oxidation is a prominent feature of dementia with Lewy bodies. Neuroreport 2002; 13: 2035–2039
   PubMed Web of Science ®Google Scholar
• Guentchev M, Siedlak SL, Jarius C, Tagliavini F, Castellani RJ, Perry G, Smith MA, Budka H. Oxidative damage to nucleic acids in human prion disease. Neurobiol Dis 2002; 9: 275–281
   PubMed Web of Science ®Google Scholar
• Petersen RB, Siedlak SL, Lee HG, Kim YS, Nunomura A, Tagliavini F, Ghetti B, Cras P, Moreira PI, Castellani RJ, Guentchev M, Budka H, Ironside JW, Gambetti P, Smith MA, Perry G. Redox metals and oxidative abnormalities in human prion diseases. Acta Neuropathol (Berl) 2005; 110: 232–238
   PubMed Web of Science ®Google Scholar
• Hayashi M, Arai N, Satoh J, Suzuki H, Katayama K, Tamagawa K, Morimatsu Y. Neurodegenerative mechanisms in subacute sclerosing panencephalitis. J Child Neurol 2002; 17: 725–730
   PubMed Web of Science ®Google Scholar
• Hayashi M, Araki S, Kohyama J, Shioda K, Fukatsu R. Oxidative nucleotide damage and superoxide dismutase expression in the brains of xeroderma pigmentosum group A and Cockayne syndrome. Brain Dev 2005; 27: 34–38
   PubMed Web of Science ®Google Scholar
• Lin CL, Chang Y, Shan X, Lai L, Tian G. Messenger RNA oxidation occurs early in disease pathogenesis and promotes motor neuron degeneration in ALS. Soc Neurosci Abstr 2007; 489: 17
   Google Scholar
• Abe T, Tohgi H, Isobe C, Murata T, Sato C. Remarkable increase in the concentration of 8- hydroxyguanosine in cerebrospinal fluid from patients with Alzheimer's disease. J Neurosci Res 2002; 70: 447–450
   PubMed Web of Science ®Google Scholar
• Abe T, Isobe C, Murata T, Sato C, Tohgi H. Alteration of 8-hydroxyguanosine concentrations in the cerebrospinal fluid and serum from patients with Parkinson's disease. Neurosci Lett 2003; 336: 105–108
   PubMed Web of Science ®Google Scholar
• Nunomura A, Perry G, Aliev G, Hirai K, Takeda A, Balraj EK, Jones PK, Ghanbari H, Wataya T, Shimohama S, Chiba S, Atwood CS, Petersen RB, Smith MA. Oxidative damage is the earliest event in Alzheimer disease. J Neuropathol Exp Neurol 2001; 60: 759–767
   PubMed Web of Science ®Google Scholar
• Nunomura A, Chiba S, Lippa CF, Cras P, Kalaria RN, Takeda A, Honda K, Smith MA, Perry G. Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease. Neurobiol Dis 2004; 17: 108–113
   PubMed Web of Science ®Google Scholar
• Ding Q, Markesbery WR, Chen Q, Li F, Keller JN. Ribosome dysfunction is an early event in Alzheimer's disease. J Neurosci 2005; 25: 9171–9175
   PubMed Web of Science ®Google Scholar
• Shan X, Chang Y, Lin CL. Messenger RNA oxidation is an early event preceding cell death and causes reduced protein expression. FASEB J 2007; 21: 2753–2764
   PubMed Web of Science ®Google Scholar
• Shan X, Tashiro H, Lin CL. The identification and characterization of oxidized RNAs in Alzheimer's disease. J Neurosci 2003; 23: 4913–4921
   PubMed Web of Science ®Google Scholar
• Shan X, Lin CL. Quantification of oxidized RNAs in Alzheimer's disease. Neurobiol Aging 2006; 27: 657–662
   PubMed Web of Science ®Google Scholar
• Cao X, Yeo G, Muotri AR, Kuwabara T, Gage FH. Noncoding RNAs in the mammalian central nervous system. Annu Rev Neurosci 2006; 29: 77–103
   PubMed Web of Science ®Google Scholar
• Honda K, Smith MA, Zhu X, Baus D, Merrick WC, Tartakoff AM, Hattier T, Harris PL, Siedlak SL, Fujioka H, Liu Q, Moreira PI, Miller FP, Nunomura A, Shimohama S, Perry G. Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron. J Biol Chem 2005; 280: 20978–20986
   PubMed Web of Science ®Google Scholar
• Gajewski E, Rao G, Nackerdien Z, Dizdaroglu M. Modification of DNA bases in mammalian chromatin by radiation-generated free radicals. Biochemistry 1990; 29: 7876–7882
   PubMed Web of Science ®Google Scholar
• Demple B, Harrison L. Repair of oxidative damage to DNA: enzymology and biology. Annu Rev Biochem 1994; 63: 915–948
   PubMed Web of Science ®Google Scholar
• Yanagawa H, Ogawa Y, Ueno M. Redox ribonucleosides. Isolation and characterization of 5- hydroxyuridine, 8-hydroxyguanosine, and 8-hydroxyadenosine from Torula yeast RNA. J Biol Chem 1992; 267: 13320–13326
   PubMed Web of Science ®Google Scholar
• Tanaka M, Chock PB, Stadtman ER. Oxidized messenger RNA induces translation errors. Proc Natl Acad Sci USA 2007; 104: 66–71
   PubMed Web of Science ®Google Scholar
• Ding Q, Martin S, Dimayuga E, Bruce-Keller AJ, Keller JN. LMP2 knock-out mice have reduced proteasome activities and increased levels of oxidatively damaged proteins. Antioxid Redox Signal 2006; 8: 130–135
   PubMed Web of Science ®Google Scholar
• Ding Q, Dimayuga E, Keller JN. Oxidative stress alters neuronal RNA- and protein-synthesis: implications for neural viability. Free Radic Res 2007; 41: 903–910
   PubMed Web of Science ®Google Scholar
• Ishibashi T, Hayakawa H, Ito R, Miyazawa M, Yamagata Y, Sekiguchi M. Mammalian enzymes for preventing transcriptional errors caused by oxidative damage. Nucleic Acids Res 2005; 33: 3779–3784
   Google Scholar
• Taddei F, Hayakawa H, Bouton M, Cirinesi A, Matic I, Sekiguchi M, Radman M. Counteraction by MutT protein of transcriptional errors caused by oxidative damage. Science 1997; 278: 128–130
   PubMed Web of Science ®Google Scholar
• Hayakawa H, Kuwano M, Sekiguchi M. Specific binding of 8-oxoguanine-containing RNA to polynucleotide phosphorylase protein. Biochemistry 2001; 40: 9977–9982
   Google Scholar
• Hayakawa H, Uchiumi T, Fukuda T, Ashizuka M, Kohno K, Kuwano M, Sekiguchi M. Binding capacity of human YB-1 protein for RNA containing 8-oxoguanine. Biochemistry 2002; 41: 12739–12744
   PubMedGoogle Scholar
• Aas PA, Otterlei M, Falnes PO, Vågbø CB, Skorpen F, Akbari M, Sundheim O, Bjørås M, Slupphaug G, Seeberg E, Krokan HE. Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA. Nature 2003; 421: 859–863
   PubMed Web of Science ®Google Scholar
• Bellacosa A, Moss EG. RNA repair: damage control. Curr Biol 2003; 13: R482–R484
   PubMed Web of Science ®Google Scholar