333
Views
4
CrossRef citations to date
0
Altmetric
Original Articles

Tissue distribution, hormonal regulation, ontogeny, diurnal expression, and induction of mouse cystine transporters Slc3a1 and Slc7a9

, &
Pages 525-534 | Received 10 Apr 2020, Accepted 10 Aug 2020, Published online: 01 Sep 2020

References

  • Orrenius S, Ormstad K, Thor H, et al. Turnover and functions of glutathione studied with isolated hepatic and renal cells. Fed Proc. 1983;42(15):3177–3188.
  • Christensen HN. Role of amino acid transport and countertransport in nutrition and metabolism. Physiol Rev. 1990;70(1):43–77.
  • Chillaron J, Estevez R, Mora C, et al. Obligatory amino acid exchange via systems bo,+-like and y + L-like. A tertiary active transport mechanism for renal reabsorption of cystine and dibasic amino acids. J Biol Chem. 1996;271(30):17761–17770.
  • Chairoungdua A, Segawa H, Kim JY, et al. Identification of an amino acid transporter associated with the cystinuria-related type II membrane glycoprotein. J Biol Chem. 1999;274(41):28845–28848.
  • Calonge MJ, Volpini V, Bisceglia L, et al. Genetic heterogeneity in cystinuria: the SLC3A1 gene is linked to type I but not to type III cystinuria. Proc Natl Acad Sci U S A. 1995;92(21):9667–9671.
  • Fernandez E, Carrascal M, Rousaud F, et al. rBAT-b(0,+)AT heterodimer is the main apical reabsorption system for cystine in the kidney. Am J Physiol Renal Physiol. 2002;283(3):F540–8.
  • Furriols M, Chillaron J, Mora C, et al. rBAT, related to L-cysteine transport, is localized to the microvilli of proximal straight tubules, and its expression is regulated in kidney by development. J Biol Chem. 1993;268(36):27060–27068.
  • Bertran J, Werner A, Moore ML, et al. Expression cloning of a cDNA from rabbit kidney cortex that induces a single transport system for cystine and dibasic and neutral amino acids. Proc Natl Acad Sci USA. 1992;89(12):5601–5605.
  • Bannai S, Kitamura E. Transport interaction of L-cystine and L-glutamate in human diploid fibroblasts in culture. J Biol Chem. 1980;255(6):2372–2376.
  • Sato H, Tamba M, Kuriyama-Matsumura K, et al. Molecular cloning and expression of human xCT, the light chain of amino acid transport system xc-. Antioxid Redox Signal. 2000;2(4):665–671.
  • Dun Y, Mysona B, Van Ells T, et al. Expression of the cystine-glutamate exchanger (xc-) in retinal ganglion cells and regulation by nitric oxide and oxidative stress. Cell Tissue Res. 2006;324(2):189–202.
  • Sato H, Kuriyama-Matsumura K, Hashimoto T, et al. Effect of oxygen on induction of the cystine transporter by bacterial lipopolysaccharide in mouse peritoneal macrophages. J Biol Chem. 2001;276(13):10407–10412.
  • Burdo J, Dargusch R, Schubert D. Distribution of the cystine/glutamate antiporter system xc- in the brain, kidney, and duodenum. J Histochem Cytochem. 2006;54(5):549–557.
  • Taguchi K, Tamba M, Bannai S, et al. Induction of cystine/glutamate transporter in bacterial lipopolysaccharide induced endotoxemia in mice. J Inflamm (Lond). 2007;4:20.
  • Buckley DB, Klaassen CD. Mechanism of gender-divergent UDP-glucuronosyltransferase mRNA expression in mouse liver and kidney. Drug Metab Dispos. 2009;37(4):834–840.
  • Wu KC, Zhang Y, Klaassen CD. Nrf2 protects against diquat-induced liver and lung injury. Free Radic Res. 2012;46(10):1220–1229.
  • Hartley DP, Klaassen CD. Detection of chemical-induced differential expression of rat hepatic cytochrome P450 mRNA transcripts using branched DNA signal amplification technology. Drug Metab Dispos. 2000;28(5):608–616.
  • Cuadrado A, Moreno-Murciano P, Pedraza-Chaverri J. The transcription factor Nrf2 as a new therapeutic target in Parkinson's disease. Expert Opin Ther Targets. 2009;13(3):319–329.
  • Mizoguchi K, Cha SH, Chairoungdua A, et al. Human cystinuria-related transporter: localization and functional characterization. Kidney Int. 2001;59(5):1821–1833.
  • Chen RS, Song YM, Zhou ZY, et al. Disruption of xCT inhibits cancer cell metastasis via the caveolin-1/beta-catenin pathway. Oncogene. 2009;28(4):599–609.
  • Lo M, Ling V, Wang YZ, et al. The xc- cystine/glutamate antiporter: a mediator of pancreatic cancer growth with a role in drug resistance. Br J Cancer. 2008;99(3):464–472.
  • Srivastava S, Chan C. Application of metabolic flux analysis to identify the mechanisms of free fatty acid toxicity to human hepatoma cell line. Biotechnol Bioeng. 2008;99(2):399–410.
  • Huang Y, Dai Z, Barbacioru C, et al. Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity and chemoresistance. Cancer Res. 2005;65(16):7446–7454.
  • Savaskan NE, Heckel A, Hahnen E, et al. Small interfering RNA-mediated xCT silencing in gliomas inhibits neurodegeneration and alleviates brain edema. Nat Med. 2008;14(6):629–632.
  • Dave MH, Schulz N, Zecevic M, et al. Expression of heteromeric amino acid transporters along the murine intestine. J Physiol (Lond). 2004;558(Pt 2):597–610.
  • Duan LP, Wang HH, Ohashi A, et al. Role of intestinal sterol transporters Abcg5, Abcg8, and Npc1l1 in cholesterol absorption in mice: gender and age effects. Am J Physiol Gastrointest Liver Physiol. 2006;290(2):G269–76.
  • Martens K, Jaeken J, Matthijs G, et al. Multi-system disorder syndromes associated with cystinuria type I. Curr Mol Med. 2008;8(6):544–550.
  • Neuschwander-Tetri BA, Rozin T. Diurnal variability of cysteine and glutathione content in the pancreas and liver of the mouse. Comp Biochem Physiol B, Biochem Mol Biol. 1996;114(1):91–95.
  • Blanco RA, Ziegler TR, Carlson BA, et al. Diurnal variation in glutathione and cysteine redox states in human plasma. Am J Clin Nutr. 2007;86(4):1016–1023.
  • Boutros M, Vicanek C, Rozen R, et al. Transient neonatal cystinuria. Kidney Int. 2005;67(2):443–448.
  • Bock KW, Kohle C. The mammalian aryl hydrocarbon (Ah) receptor: from mediator of dioxin toxicity toward physiological functions in skin and liver. Biol Chem. 2009;390(12):1225–1235.
  • di Masi A, De Marinis E, Ascenzi P, et al. Nuclear receptors CAR and PXR: molecular, functional, and biomedical aspects. Mol Aspects Med. 2009;30(5):297–343.
  • Eder K, Ringseis R. The role of peroxisome proliferator-activated receptor alpha in transcriptional regulation of novel organic cation transporters. Eur J Pharmacol. 2010;628(1-3):1–5.
  • Klaassen CD, Reisman SA. Nrf2 the rescue: effects of the antioxidative/electrophilic response on the liver. Toxicol Appl Pharmacol. 2010;244(1):57–65.
  • Sasaki H, Sato H, Kuriyama-Matsumura K, et al. Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression. J Biol Chem. 2002;277(47):44765–44771.
  • Takahata Y, Takarada T, Iemata M, et al. Functional expression of beta2 adrenergic receptors responsible for protection against oxidative stress through promotion of glutathione synthesis after Nrf2 upregulation in undifferentiated mesenchymal C3H10T1/2 stem cells. J Cell Physiol. 2009;218(2):268–275.
  • Drechsel DA, Patel M. Differential contribution of the mitochondrial respiratory chain complexes to reactive oxygen species production by redox cycling agents implicated in parkinsonism. Toxicol Sci. 2009;112(2):427–434.
  • Hinson JA, Roberts DW, James LP. Mechanisms of acetaminophen-induced liver necrosis. Handb Exp Pharmacol. 2010;196:369–405.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.