References
- Zappa C, Mousa SA. Non-small cell lung cancer: current treatment and future advances. Transl Lung Cancer Res. 2016;5(3):288–300.
- Kalluri R, Weinberg RA. The basics of epithelial-mesenchymal transition. J Clin Invest. 2009;119(6):1420–1428.
- Baranwal S, Alahari SK. Molecular mechanisms controlling E-cadherin expression in breast cancer. Biochem Biophys Res Commun. 2009;384(1):6–11.
- Nagaraja SS, Nagarajan D. Radiation-Induced Pulmonary Epithelial-Mesenchymal Transition: A Review on Targeting Molecular Pathways and Mediators. Curr Drug Targets. 2018;19(10):1191–1204.
- Nagarajan D, Melo T, Deng Z, et al. ERK/GSK3β/Snail signaling mediates radiation-induced alveolar epithelial-to-mesenchymal transition. Free Radic Biol Med. 2012;52(6):983–992.
- Serrano-Gomez SJ, Maziveyi M, Alahari SK. Regulation of epithelial-mesenchymal transition through epigenetic and post-translational modifications. Mol Cancer. 2016;15:18.
- Shrishrimal S, Kosmacek EA, Oberley-Deegan RE. Reactive oxygen species drive epigenetic changes in radiation-induced fibrosis. Oxid Med Cell Longev. 2019;2019:4278658.
- Li R, Ong SL, Tran LM, et al. Chronic IL-1beta-induced inflammation regulates epithelial-to-mesenchymal transition memory phenotypes via epigenetic modifications in non-small cell lung cancer. Sci Rep. 2020;10(1):377.
- Chen Y, Liu W, Wang P, et al. Halofuginone inhibits radiotherapy-induced epithelial-mesenchymal transition in lung cancer. Oncotarget. 2016;7(44):71341–71352.
- Ji Q, Liu X, Han Z, et al. Resveratrol suppresses epithelial-to-mesenchymal transition in colorectal cancer through TGF-β1/Smads signaling pathway mediated Snail/E-cadherin expression. BMC Cancer. 2015;15:97.
- Elseweidy MM, Askar ME, Elswefy SE, et al. Vanillin as a new modulator candidate for renal injury induced by cisplatin in experimental rats. Cytokine. 2017;99:260–265.
- Zabad IEM, Amin MN, El-Shishtawy MM. Protective effect of vanillin on diabetic nephropathy by decreasing advanced glycation end products in rats. Life Sci. 2019;239:117088.
- Bese NS, Umay C, Yildirim S, et al. The effects of tamoxifen on radiation-induced pulmonary fibrosis in Wistar albino rats: Results of an experimental study. Breast. 2006;15:456–460.
- Beaudry F, Ross A, Lema PP, et al. Pharmacokinetics of vanillin and its effects on mechanical hypersensitivity in a rat model of neuropathic pain. Phytother Res. 2010;24(4):525–530.
- Ben Saad H, Driss D, Ellouz Chaabouni S, et al. Vanillin mitigates potassium bromate-induced molecular, biochemical and histopathological changes in the kidney of adult mice. Chem Biol Interact. 2016;252:102–113.
- Zhang J, Cui R, Feng Y, et al. Serotonin Exhibits Accelerated Bleomycin-Induced Pulmonary Fibrosis through TPH1 Knockout Mouse Experiments. Mediators Inflamm. 2018;2018:7967868
- Sharma SH, Kumar JS, Chellappan DR, et al. Molecular chemoprevention by morin - A plant flavonoid that targets nuclear factor kappa B in experimental colon cancer. Biomed Pharmacother. 2018;100:367–373.
- Nagaraja SS, Krishnamoorthy V, Raviraj R, et al. Effect of Trichostatin A on radiation induced epithelial-mesenchymal transition in A549 cells. Biochem Biophys Res Commun. 2017;493(4):1534–1541.
- Chowdhury S, Ghosh S, Rashid K, et al. Deciphering the role of ferulic acid against streptozotocin-induced cellular stress in the cardiac tissue of diabetic rats. Food Chem Toxicol. 2016;97:187–198.
- Chowdhury S, Ghosh S, Das AK, et al. Ferulic acid protects hyperglycemia-induced kidney damage by regulating oxidative insult, inflammation and autophagy. Front Pharmacol. 2019;10:27.
- Rahman I, Kode A, Biswas SK. Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method. Nat Protoc. 2006;1(6):3159–3165.
- Mannervik B, Alin P, Guthenberg C, et al. Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties. Proc Natl Acad Sci USA. 1985;82(21):7202–7206.
- Bradley PP, Priebat DA, Christensen RD, et al. Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. J Invest Dermatol. 1982;78(3):206–209.
- Levine RL, Garland D, Oliver CN, et al. Determination of carbonyl content in oxidatively modified proteins. Meth Enzymol. 1990;186:464–478.
- Meyer KC, Raghu G. Bronchoalveolar lavage for the evaluation of interstitial lung disease: is it clinically useful?. Eur Respir J. 2011;38(4):761–769.
- Gao L, Tang H, He H, et al. Glycyrrhizic acid alleviates bleomycin-induced pulmonary fibrosis in rats. Front Pharmacol. 2015;6:215.
- Trujillo KA, Heaphy CM, Mai M, et al. Markers of fibrosis and epithelial to mesenchymal transition demonstrate field cancerization in histologically normal tissue adjacent to breast tumors. Int J Cancer. 2011;129(6):1310–1321.
- Dong C, Wu Y, Wang Y, et al. Interaction with Suv39H1 is critical for Snail-mediated E-cadherin repression in breast cancer. Oncogene. 2013;32(11):1351–1362.
- Wang JS, Wang HJ, Qian HL. Biological effects of radiation on cancer cells. Mil Med Res. 2018;5(1):20.
- Ping Z, Peng Y, Lang H, et al. Oxidative stress in radiation-induced cardiotoxicity. Oxid Med Cell Longev. 2020;2020:3579143
- Sharma P, Jha AB, Dubey RS, et al. Reactive oxygen species, oxidative damage, and antioxidative defense mechanism in plants under stressful conditions. Journal of Botany. 2012;2012:1–26.
- Giuranno L, Ient J, De Ruysscher D, et al. Radiation-Induced Lung Injury (RILI). Front Oncol. 2019;9:877.
- Sunil Gowda NS, Raviraj R, Nagarajan D, et al. Radiation-induced lung injury: impact on macrophage dysregulation and lipid alteration - a review. Immunopharmacol Immunotoxicol. 2019;41(3):370–379.
- Chen L, Deng H, Cui H, et al. Inflammatory responses and inflammation-associated diseases in organs. Oncotarget. 2018;9(6):7204–7218.
- Salton F, Volpe MC, Confalonieri M. Epithelial(-)Mesenchymal Transition in the pathogenesis of idiopathic pulmonary fibrosis. Medicina. 2019;55.
- Sundararajan V, Tan M, Tan TZ, et al. SNAI1 recruits HDAC1 to suppress SNAI2 transcription during epithelial to mesenchymal transition. Sci Rep. 2019;9(1):8295.
- Hyun K, Jeon J, Park K, et al. Writing, erasing and reading histone lysine methylations. Exp Mol Med. 2017;49(4):e324.
- Chaturvedi CP, Somasundaram B, Singh K, et al. Maintenance of gene silencing by the coordinate action of the H3K9 methyltransferase G9a/KMT1C and the H3K4 demethylase Jarid1a/KDM5A. Proc Natl Acad Sci Usa. 2012;109(46):18845–18850.
- Kaniskan HU, Martini ML, Jin J. Inhibitors of protein methyltransferases and demethylases. Chem Rev. 2018;118(3):989–1068.
- Simon-Tillaux N, Hertig A. Snail and kidney fibrosis. Nephrology, dialysis, transplantation: official publication of the European dialysis and transplant association. European Renal Assoc. 2017;32:224–233.
- Skrypek N, Goossens S, De Smedt E, et al. Epithelial-to-mesenchymal transition: epigenetic reprogramming driving cellular plasticity. Trends Genet. 2017;33(12):943–959.
- Ben Saad H, Ben Amara I, Krayem N, et al. Ameliorative effects of vanillin on potassium bromate induces bone and blood disorders in vivo. Cell. Mol. Biol. (Noisy-le-Grand). 2015;61(7):12–22.
- Rawat C, Kukal S, Dahiya UR, et al. Cyclooxygenase-2 (COX-2) inhibitors: future therapeutic strategies for epilepsy management. J Neuroinflammation. 2019;16(1):197.
- Makni M, Chtourou Y, Fetoui H, et al. Evaluation of the antioxidant, anti-inflammatory and hepatoprotective properties of vanillin in carbon tetrachloride-treated rats. Eur J Pharmacol. 2011;668(1-2):133–139.
- Guo T, Su Z, Wang Q, et al. Vanillin protects lipopolysaccharide-induced acute lung injury by inhibiting ERK1/2, p38 and NF-κB pathway. Future Med Chem. 2019;11(16):2081–2094.