Time course of dopaminergic cell death and changes in iron, ferritin and transferrin levels in the rat substantia nigra after 6-hydroxydopamine (6-OHDA) lesioning

References

• Halliwell B. Reactive oxygen species and the central nervous system. Journal of Neurochemistry 1992; 59: 1609–1623
   PubMed Web of Science ®Google Scholar
• Dexter D.T., Cater C.J., Wells F.R., Javoy-Agid F., Agid Y., Lees A., Jenner P., Marsden C.D. Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease. Journal of Neurochemistry 1989; 52: 381–389
   PubMed Web of Science ®Google Scholar
• Dwork A.J., Schon E.A., Herbert J. Nonidentical distribution of transferrin and ferric iron in human brain. Neuroscience 1988; 27: 333–345
   PubMed Web of Science ®Google Scholar
• Gerlach M., Riederer P. The pathophysiological basis of Parkinson's disease. Inhibitors of Monoamine Oxidase B. Pharmacology and Clinical Use in Neurodegenerative Disorders, I. Szelenyi. Birkhäuser, Basel 1993; 26–50, In
   Google Scholar
• Jenner P. Oxidative stess as a cause of Parkinson's disease. Acta Neurologica Scandinavica 1991; 136: 6–15, (Suppl.)
   Google Scholar
• Lange K.W., Youdim M.B.H., Riederer P. Neurotoxicity and neuroprotection in Parkinson's disease. Journal of Neural Transmission 1992; 38: 27–44, (Suppl.)
   Google Scholar
• Sofic E., Riederer P., Heinsen H., Bechmann H., Reynolds G.P., Hebenstreit G., Youdim M.B.H. Increased iron (III) and total iron content in post mortem substantia nigra of parkinsonian brain. Journal of Neural Transmission 1988; 74: 199–205
   PubMed Web of Science ®Google Scholar
• Halliwell B., Gutteridge J. Oxygen radicals and the nervous system. Trends in Neuroscience 1985; 8: 22–29
   Web of Science ®Google Scholar
• Olanow C.W. Oxidation reactions in Parkinson's disease. Neurology 1990; 40: 32–37
   PubMed Web of Science ®Google Scholar
• Galazka-Friedman J., Bauminger E.R., Friedman A., Barcikowska M., Hechel D., Nowik I. Iron in parkinsonian and control substantia nigra: a Mössbauer spectroscopy study. Movement Disorders 1996; 11: 8–16
   PubMed Web of Science ®Google Scholar
• Sofic E., Paulus W., Jellinger K., Riederer P., Youdim M.B.H. Selective increase of iron in substantia nigra zona compacta of parkinsonian brains. Journal of Neurochemistry 1991; 56: 978–982
   PubMed Web of Science ®Google Scholar
• Riederer P., Sofic E., Rausch W.D., Schmidt B., Reynolds G.P., Jellinger K., Youdim M.B.H. Transition metals, ferritin, glutathione, and ascorbic acid in parkinsonian brains. Journal of Neurochemistry 1989; 52: 515–520
   PubMed Web of Science ®Google Scholar
• Good P.F., Olanow C.W., Perl D.P. Neuromelanin-containing neurons of the substantia nigra accumulate iron and aluminum in Parkinson's disease: a LAMMA study. Brain Research 1992; 593: 343–346
   PubMed Web of Science ®Google Scholar
• Mochizuki H., Imai H., Endo K., Yokomizo K., Murata Y., Hattori N., Mizuno Y. Iron accumulation in the substantia nigra of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced hemiparkinsonian monkeys. Neuroscience Letters 1994; 168: 251–253
   PubMed Web of Science ®Google Scholar
• Temlett J.A., Landsberg J.P., Watt F., Grime G.W. Increased iron in the substantia nigra compacta of the MPTP-lesioned hemiparkinsonian african green monkey: evidence from proton microprobe elemental microanalysis. Journal of Neurochemistry 1994; 62: 134–146
   PubMed Web of Science ®Google Scholar
• Oestreicher E., Sengstock G.J., Riederer P., Olanow C.W., Dunn A.J., Arendash G.W. Degeneration of nigrostriatal dopaminergic neurones increases iron within the substantia nigra: a histochemical and neurochemical study. Brain Research 1994; 660: 8–18
   PubMed Web of Science ®Google Scholar
• He Y., Thong P.S.P., Lee T., Leong S.K., Shi C.Y., Wong P.T.H., Yuan S.Y., Watt F. Increased iron in the substantia nigra of 6-OHDA induced parkinsonian rats: a nuclear microscopy study. Brain Research 1996; 735: 149–153
   PubMed Web of Science ®Google Scholar
• Ben-Shachar D., Youdim M.B.H. Intranigral iron injection induces behavioral and biochemical “parkinsonism” in rats. Journal of Neurochemistry 1991; 57: 2133–2135
   PubMed Web of Science ®Google Scholar
• Sengstock G.W., Olanow C.W., Menzies R.A., Dunn A.J., Arendash G.W. Infusion of iron into the rat substantia nigra: nigral pathology and dose dependent loss of dopaminergic markers. Journal of Neuroscience Research 1993; 35: 67–82
   PubMed Web of Science ®Google Scholar
• Faucheux B.A., Nillesse N., Damier P., Spik G., Pierce A., Leveugle B., Kubis N., Hauw J.J., Agid Y., Hirsch E.C. Expression of lactoferrin receptors is increased in the mesencephalon of patients with Parkinson's disease. Proceedings of the National Academy of Science of the United States 1995; 92: 9603–9607
   PubMed Web of Science ®Google Scholar
• Leveugle B., Faucheux B.A., Bouras C., Nillesse N., Spk G., Hirsch E.C., Agid Y., Hof P.R. Cellular distribution of the iron-binding protein lactotransferrin in the mesencephalon of Parkinson's disease cases. Acta Neuropathology 1996; 91: 566–572
   PubMed Web of Science ®Google Scholar
• Aisen P. Entry of iron into cells: A new role for the transferrin receptor in modulating iron release from transferrin. Annals Neurology 1992; 32: S62–S68
   Web of Science ®Google Scholar
• Connor J.R., Snyder B.S., Beard J.L., Fine R.E., Mufson E.J. The regional distribution of iron and iron regulatory proteins in the brain in aging and Alzheimer's disease. Journal of Neuroscience Research 1992; 31: 327–335
   PubMed Web of Science ®Google Scholar
• Theil E.C. Ferrintin: structure, gene regulation, and cellular function in animals, plants and microorganisms. Annual Review of Biochemistry 1987; 56: 289–315
   PubMed Web of Science ®Google Scholar
• Iancu T.C. Ferritin and hemosiderin in pathological tissures. Electron Microscopy Review 1992; 5: 209–229
   PubMedGoogle Scholar
• Boyd D., Vecoli C., Belcher D.M., Jain S.K., Drysdale J.W. Structural and functional relationships of human ferritin H and L chains deduced from cDNA clones. Journal of Biological Chemistry 1985; 260: 11755–11761
   PubMed Web of Science ®Google Scholar
• Paxinos G., Watson C. The Rat Brain in Stereotaxic Coordinates. Academic Press, New York 1986
   Google Scholar
• Connor J.R., Menzies S.L., St. Martin S.L., Mufson E.J. Cellular distribution of transferrin, ferritin and iron in normal and aged human brains. Journal of Neuroscience Research 1990; 27: 595–611
   PubMed Web of Science ®Google Scholar
• Hill J.M., Switzer R.C. The regional distribution and cellular localisation of iron in the rat brain. Neuroscience 1984; 11: 595–603
   PubMed Web of Science ®Google Scholar
• Levine S.M., Machlin W.B. Iron-enriched oligodendrocytes: a reexamination of their spatial distribution. Journal of Neuroscience Research 1990; 26: 508–512
   PubMed Web of Science ®Google Scholar
• Koeppen A.H. The history of iron in the brain. Journal of Neurological Science 1995; 134: 1–9, (s)
   PubMed Web of Science ®Google Scholar
• Uitti R.J., Rajput A.H., Rozdilsky B., Bickis M., Wollin T., Yuen W.K. Regional metal concentrations in Parkinson's disease, other chronic neurological disease, and control brains. Canadian Journal of Neurological Science 1989; 16: 310–314
   PubMed Web of Science ®Google Scholar
• Connor J.R., Boeshore K., Benkovic S.A., Menzies S.L. Isoforms of ferritin have a specific cellular distribution in the brain. Journal of Neuroscience Research 1994; 37: 461–465
   PubMed Web of Science ®Google Scholar
• Leveugle B., Spik G., Perl D.P., Bouras C., Fillit H.M., Hof P.R. The iron binding protein lactotransferrin is present in pathologic lesions in a variety of neurodegenerative disorders: a comparative immunohistochemical analysis. 1994
   Google Scholar
• Brain Research, 650: 20–31
   PubMed Web of Science ®Google Scholar
• Bloch B., Popocici T., Levin M.J., Tuil D., Kahn A. Transferrin gene expression visualized in oligodendrocytes of the rat brain using in situ hybridization and immunohistochemistry. Proceedings of the National Academy of Science of the United States 1985; 82: 6706–6710
   PubMed Web of Science ®Google Scholar
• Morris C.M., Candy J.M., Bloxham C.A., Edwardson J.A. Immunocytochemical localisation of transferrin in the human brain. Acta Anatomy 1992; 143: 14–18
   Google Scholar
• van-Kamp G.J., Mulder K., Kuiper M., Wolters E.C. Changed transferrin sialylation in Parkinson's disease. Clinica Chimica Acta 1995; 235: 159–167
   PubMed Web of Science ®Google Scholar
• Cabrera-Valdivia F., Jimenez-Jimenez F.J., Molina J.A., Fernandez-Calle P., Vazquen A., Canizares-Liebana F., Laurmbe-Bobalde S., Ayuso-Peralta L., Rabasa M., Codoceo R. Peripheral iron metabolism in patients with Parkinson's disease. Journal of Neurological Science 1994; 125: 82–86
   PubMed Web of Science ®Google Scholar
• Loeffler D.A., Connor J.R., Juneau P.L., Snyder B.S., Kanaley L., DeMaggio A.J., Nguyen H., Brickman C.M., LeWitt P.A. Transferrin and iron in normal, Alzheimer's disease, and Parkinson's disease brain regions. Journal of Neurochemistry 1995; 65: 710–716
   PubMed Web of Science ®Google Scholar
• Dexter D.T., Carter C.J., Bidailhet M., Rubert M., Agid F., Agid Y., Lees A.J., Wells F.R., Jenner P., Marsden C.D. Decreased ferrintin levels in brain in Parkinson's disease. Journal of Neurochemistry 1990; 55: 16–20
   PubMed Web of Science ®Google Scholar
• Pantopoulos K., Weiss G., Hentze M.W. Nitric oxide activates iron regulatory factor and affects the post-transcriptional control of cellular iron metabolism. The biology of Nitric Oxide, S. Moncada, M. Feelisch, R. Busse, E.A. Higgs. Portland Press, London 1994; 24–31, In
   Google Scholar
• Jellinger K., Paulus W., Grundke-Iqbal I., Riederer P., Youdim M.B.H. Brain iron and ferritin in Parkinson's and Alzheimer's diseases. Journal of Neural Transmission — Parkinsons Disease and Dementia Section 1990; 2: 327–340
   PubMedGoogle Scholar
• Connor J.R., Snyder B.S., Arosio P., Loeffler D.A., LeWitt P. A quantitative analysis of isoferritins in select regions of aged, Parkinsonian, and Alzheimer's disease brains. Journal of Neurochemistry 1995; 65: 717–724
   PubMed Web of Science ®Google Scholar
• Goto K., Mochizuki H., Imai H., Akiyama H., Mizuno Y. An immunohistochemical study of ferritin in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)-induced hemiparkinsonian monkeys. Brain Research 1996; 724: 125–128
   PubMed Web of Science ®Google Scholar
• Youshida T., Tanaka M., Sotomatsu A., Hirai S. Activated microglia cause superoxide-mediated release of iron from ferritin. Neuroscience Letters 1995; 190: 21–24
   PubMed Web of Science ®Google Scholar